| Publication |
Sentence |
Publish Date |
Extraction Date |
Species |
| J Pagnier, J Elion, C Lapouméroulie, C Vigneron, D Labi. Homozygous deletional alpha + thalassaemia associated with unequal expression of the two remaining alpha 1 genes (alpha 1A and alpha 1Q). British journal of haematology. vol 52. issue 1. 1982-12-03. PMID:7115621. |
a cambodian family presenting several haemoglobinopathies, hb e, hb q and alpha + thalassaemia, has been investigated. |
1982-12-03 |
2023-08-12 |
Not clear |
| V S Sharma, M E John, M R Waterma. Functional studies on hemoglobin opossum. Conclusions drawn regarding the role of the distal histidine. The Journal of biological chemistry. vol 257. issue 20. 1982-12-03. PMID:7118915. |
comparison of kinetic studies of opossum hemoglobin with normal human hemoglobin shows that alpha chains in hb opossum, despite the lack of distal histidine, do not differ significantly in co-combination rates in either the t or r states. |
1982-12-03 |
2023-08-12 |
human |
| D M Hunt, D R Higgs, P Winichagoon, J B Clegg, D J Weatheral. Haemoglobin Constant Spring has an unstable alpha chain messenger RNA. British journal of haematology. vol 51. issue 3. 1982-10-12. PMID:7104225. |
haemoglobin constant spring (hb cs) is a variant with an elongated alpha-chain associated with an alpha + thalassaemia phenotype. |
1982-10-12 |
2023-08-12 |
Not clear |
| D M Hunt, D R Higgs, P Winichagoon, J B Clegg, D J Weatheral. Haemoglobin Constant Spring has an unstable alpha chain messenger RNA. British journal of haematology. vol 51. issue 3. 1982-10-12. PMID:7104225. |
the amount of alpha mrna relative to beta mrna in reticulocytes was reduced in carriers of hb cs by an amount equivalent to the reduction observed in carriers of alpha + thalassaemia. |
1982-10-12 |
2023-08-12 |
Not clear |
| J M Friedman, R A Stepnoski, M Stavola, M R Ondrias, R L Con. Ligation and quaternary structure induced changes in the heme pocket of hemoglobin: a transient resonance Raman study. Biochemistry. vol 21. issue 9. 1982-09-10. PMID:7093226. |
with respect to the structural parameter responsible for variations in the pi orbital electron density of the porphyrin, the degree of alteration of the heme pocket configuration relative to deoxy-hb(t) follows the sequence: liganded hb(r) greater than liganded hb(r) + ihp greater than liganded hb(t) [alpha chain greater than beta chain] greater than deoxy-hb(r). |
1982-09-10 |
2023-08-12 |
Not clear |
| T B Shih, R T Jones, C S Johnso. Functional properties of Hb Pasadena, alpha 2 beta 2 75(E 19) Leu replaced by Arg. Hemoglobin. vol 6. issue 2. 1982-09-10. PMID:7096106. |
functional properties of hb pasadena, alpha 2 beta 2 75(e 19) leu replaced by arg. |
1982-09-10 |
2023-08-12 |
Not clear |
| D K Bowden, L Pressley, D R Higgs, J B Clegg, D J Weatheral. alpha-globin gene deletions associated with Hb J Tongariki. British journal of haematology. vol 51. issue 2. 1982-08-14. PMID:6979350. |
three identical alpha + thalassemia genes, one of which always carried the hb j tongariki mutation, have been observed in vanuatuans. |
1982-08-14 |
2023-08-12 |
Not clear |
| D R Higgs, J Lamb, B E Aldridge, J B Clegg, D J Weatherall, B E Serjeant, G R Serjean. Inadequacy of Hb Bart's as an indicator of alpha thalassaemia. British journal of haematology. vol 51. issue 1. 1982-07-22. PMID:6896154. |
inadequacy of hb bart's as an indicator of alpha thalassaemia. |
1982-07-22 |
2023-08-12 |
Not clear |
| M B Gardiner, J Carver, B L Abraham, J B Wilson, T H Huisma. Further studies on the quantitation of the hemoglobins A, S, C, and F in newborn babies with different hemoglobinopathies using high pressure liquid chromatography. Hemoglobin. vol 6. issue 1. 1982-06-21. PMID:6175601. |
data for a few hundred cord blood samples indicate a great variability in the relative quantities of hb s or hb c in heterozygotes which prevents a definitive diagnosis of a simultaneously occurring alpha-thalassemia except perhaps of the homozygous form of alpha-thalassemia-2 (alpha o alpha/alpha o alpha). |
1982-06-21 |
2023-08-12 |
Not clear |
| Y Ohba, Y Hattori, M Matsuoka, T Miyaji, K Fuyun. HB Kokura [alpha 47 (CE 5) Asp leads to Gly]: a slightly unstable variant. Hemoglobin. vol 6. issue 1. 1982-06-21. PMID:7068437. |
hb kokura [alpha 47 (ce 5) asp leads to gly]: a slightly unstable variant. |
1982-06-21 |
2023-08-12 |
Not clear |
| A M Li, F T Lee, D Tod. The screening of Chinese cord blood for haemoglobinopathies. Human heredity. vol 32. issue 1. 1982-06-14. PMID:6896042. |
3 out of 4 other babies had different haemoglobin variants, namely hb alpha q, hb j and hb new york. |
1982-06-14 |
2023-08-12 |
Not clear |
| Y T Zeng, S Z Huang, L Xu, G F Long, H Lam, J B Wilson, T H Huisma. Hb Wuming or alpha 2 11(A9)Lys substituting for Gln beta 2. Hemoglobin. vol 5. issue 7-8. 1982-06-14. PMID:7338470. |
hb wuming or alpha 2 11(a9)lys substituting for gln beta 2. |
1982-06-14 |
2023-08-12 |
Not clear |
| Y T Zen. [Hb Wuming (alpha 11 (A9) Lys leads to Glu)---a new variant found in China (author's transl)]. Zhonghua yi xue za zhi. vol 61. issue 10. 1982-05-27. PMID:6800600. |
[hb wuming (alpha 11 (a9) lys leads to glu)---a new variant found in china (author's transl)]. |
1982-05-27 |
2023-08-12 |
Not clear |
| J E Fuhr, E Bamberger, C B Lozzio, B B Lozzio, A E Felice, G Altay, B B Webber, A L Reese, S M Mayson, T H Huisma. Identification and quantitation of embryonic and three types of fetal hemoglobin produced on induction of the human pluripotent leukemia cell line K-562 with hemin. American journal of hematology. vol 12. issue 1. 1982-05-21. PMID:6175208. |
zone 1: alpha 2 epsilon 2, or hb gower-2; zone 2: zeta 2 epsilon 2, or hb gower-1; zone 3: zeta 2 gamma 2, or hb portland-i; zone 4: hb f, or alpha 2 gamma 2; zone 5: a mixture of acetylated hb portland-i and hb f; zone 6: hb bart's, or gamma 4. |
1982-05-21 |
2023-08-12 |
human |
| L E Lie-Injo, A Solai, A R Herrera, L Nicolaisen, Y W Kan, W P Wan, K Hasa. Hb Bart's level in cord blood and deletions of alpha-globin genes. Blood. vol 59. issue 2. 1982-04-12. PMID:6895707. |
all 16 dna samples from cord blood with hb bart's below 3% and no other abnormal hemoglobin had one alpha-globin gene deletion (alpha thal2), except one which had two alpha-globin gene deletions (alpha thal1). |
1982-04-12 |
2023-08-12 |
Not clear |
| L E Lie-Injo, A Solai, A R Herrera, L Nicolaisen, Y W Kan, W P Wan, K Hasa. Hb Bart's level in cord blood and deletions of alpha-globin genes. Blood. vol 59. issue 2. 1982-04-12. PMID:6895707. |
all 14 cases with hb bart's between 3.5% and 8.5% and no other abnormal hemoglobin had two alpha-globin gene deletions (alpha thal1), except one that did not have any alpha-globin gene deletion and one that had one alpha-globin gene deletion. |
1982-04-12 |
2023-08-12 |
Not clear |
| L E Lie-Injo, A Solai, A R Herrera, L Nicolaisen, Y W Kan, W P Wan, K Hasa. Hb Bart's level in cord blood and deletions of alpha-globin genes. Blood. vol 59. issue 2. 1982-04-12. PMID:6895707. |
sixty-five dna samples from cord blood without hb bart's or other abnormal hemoglobin had no alpha-globin gene deletions, except one that had one alpha-globin gene deletion (alpha thal2). |
1982-04-12 |
2023-08-12 |
Not clear |
| H Mizukoshi, M Itoh, S Matsukawa, K Mawatari, Y Yoneyam. Tryptophan fluorescence of human hemoglobin. II. Effect of inositol hexaphosphate on the T-R transition. Biochimica et biophysica acta. vol 700. issue 2. 1982-04-12. PMID:7055577. |
the fluorescence intensity of hba, hb kempsey (beta 99 asp-asn), hb chesapeake (alpha 92 arg-leu) and nes-des-arg hb (des-141 alpha arg and beta 93 cys-n-ethylsuccinimide derivative) in the presence of inositol hexaphosphate exhibits a considerable decrease in the deoxy to oxy transition, while no or slight fluorescence intensity change was observed in the deoxy to oxy transition of hb kempsey and nes-des-arg hb in the absence of inositol hexaphosphate. |
1982-04-12 |
2023-08-12 |
human |
| K Nagai, Y Enoki, S Tomita, T Teshim. Trypsin-catalyzed synthesis of peptide bond in human hemoglobin. Oxygen binding characteristics of Gly-NH2(142 alpha) Hb. The Journal of biological chemistry. vol 257. issue 4. 1982-04-12. PMID:7056733. |
oxygen binding characteristics of gly-nh2(142 alpha) hb. |
1982-04-12 |
2023-08-12 |
human |
| K Nagai, Y Enoki, S Tomita, T Teshim. Trypsin-catalyzed synthesis of peptide bond in human hemoglobin. Oxygen binding characteristics of Gly-NH2(142 alpha) Hb. The Journal of biological chemistry. vol 257. issue 4. 1982-04-12. PMID:7056733. |
structural analyses, including digestion with trypsin and carboxypeptidases a and b, have shown that one is unmodified hb a and the other is gly-nh2(142 alpha) hb in which gly-nh2 is bound to the cooh-terminal residue of the alpha subunit (arg 141 alpha) via peptide bond. |
1982-04-12 |
2023-08-12 |
human |