| Publication |
Sentence |
Publish Date |
Extraction Date |
Species |
| T Nakatsuji, J Carver, J B Wilson, H Lam, A L Reese, S Nagle, S Miwa, T H Huisma. alpha Chain and gamma chain abnormal hemoglobins in newborn babies: structural and genetic aspects. American journal of hematology. vol 14. issue 2. 1983-05-05. PMID:6188374. |
the relative amount of the alpha x containing abnormal hb f of the hb g-philadelphia and hb winnipeg babies was less than observed in heterozygous adults, which may indicate a decreased rate of assembly of the alpha x-gamma dimer over that of the alpha x-beta dimer. |
1983-05-05 |
2023-08-12 |
Not clear |
| R Gambar. [Expression of genes for human globin in the cell line K-562: an experimental model for the study of fetal erythropoiesis]. Bollettino della Societa italiana di biologia sperimentale. vol 58. issue 22. 1983-05-05. PMID:7165753. |
k-562(s6) cells accumulate, upon exposure to 75 microm hemin, mostly hb gower 1 (zeta 2 epsilon 2) and low amounts of hb x (epsilon 2 gamma 2) and hb portland (zeta 2 gamma 2), being suitable for studies focused on the expression of embryonic globin genes and on the molecular mechanisms controlling the switching from embryonic-type to fetal-type hemoglobin accumulation, when in the human embryo zeta and epsilon globin genes become less active, being sharply increased accumulation of alpha and gamma globin chains. |
1983-05-05 |
2023-08-12 |
human |
| G Trabuchet, F Morle, G Verdier, J Godet, M Benabadji, V M Nigo. Mapping the alpha-globin genes in Hb J Mexico carriers. Human genetics. vol 62. issue 2. 1983-04-21. PMID:6298095. |
the organization of the alpha-globin genes was studied by restriction endonuclease mapping, in subjects carrying the alpha variant hb j mexico. |
1983-04-21 |
2023-08-12 |
human |
| G Trabuchet, F Morle, G Verdier, J Godet, M Benabadji, V M Nigo. Mapping the alpha-globin genes in Hb J Mexico carriers. Human genetics. vol 62. issue 2. 1983-04-21. PMID:6298095. |
a subject homozygous for hb j synthesized both hb j (about 55%) and hb a and had two alpha loci per chromosome. |
1983-04-21 |
2023-08-12 |
human |
| G Trabuchet, F Morle, G Verdier, J Godet, M Benabadji, V M Nigo. Mapping the alpha-globin genes in Hb J Mexico carriers. Human genetics. vol 62. issue 2. 1983-04-21. PMID:6298095. |
we have also mapped the dna of a compound heterozygote for hb j and alpha-thalassemia, who synthesizes 38% hb j and we have found a single alpha gene corresponding to a - alpha 3.7 haplotype on one chromosome and two alpha genes, respectively alpha j and alpha a, on the other. |
1983-04-21 |
2023-08-12 |
human |
| G Martínez, R Menénde. Differences in affinity of beta and delta hemoglobin chains for alpha chains. A possible explanation for the variation in the percentages of hemoglobin A2 in thalassemia and other disorders. Biochimica et biophysica acta. vol 743. issue 2. 1983-04-21. PMID:6824703. |
when alpha chains were present in an amount equal to or greater than that of the mixture of beta and delta chains, the amount of hb a2 was similar to that of hb a. |
1983-04-21 |
2023-08-12 |
human |
| G Martínez, R Menénde. Differences in affinity of beta and delta hemoglobin chains for alpha chains. A possible explanation for the variation in the percentages of hemoglobin A2 in thalassemia and other disorders. Biochimica et biophysica acta. vol 743. issue 2. 1983-04-21. PMID:6824703. |
when alpha chains were in limiting concentrations, more hb a than a2 was always formed with gradually decreasing amounts of hb a2. |
1983-04-21 |
2023-08-12 |
human |
| M D Rhoda, J Martin, Y Blouquit, M C Garel, S J Edelstein, J Ros. Sickle cell hemoglobin fiber formation strongly inhibited by the Stanleyville II mutation (alpha 78 Asn leads to Lys). Biochemical and biophysical research communications. vol 111. issue 1. 1983-04-15. PMID:6681956. |
a double mutant hemoglobin possessing both the hb s (beta 6 glu leads to val) and the hb stanleyville ii (alpha 78 asn leads to lys) mutations has been purified from the blood of a donor heterozygous for both of the mutations. |
1983-04-15 |
2023-08-12 |
Not clear |
| G Efremov, N Stojanovski, B Nastev, C Zisovsk. [Alpha thalassemia in Macedonia]. Bilten za hematologiju i transfuziju. vol 9. issue 1-3. 1983-04-15. PMID:7349757. |
the frequency of alpha thalassemia in sr macedonia was determined with studies of hb bart's in 1.140 newborn babies. |
1983-04-15 |
2023-08-12 |
Not clear |
| G Efremov, N Stojanovski, B Nastev, C Zisovsk. [Alpha thalassemia in Macedonia]. Bilten za hematologiju i transfuziju. vol 9. issue 1-3. 1983-04-15. PMID:7349757. |
biosynthetic studies of family members of the eight individuals with hb h disease showed that one parent is heterozygous alpha thal1 while the other is heterozygous alpha thal2. |
1983-04-15 |
2023-08-12 |
Not clear |
| G Efremov, N Stojanovski, B Nastev, C Zisovsk. [Alpha thalassemia in Macedonia]. Bilten za hematologiju i transfuziju. vol 9. issue 1-3. 1983-04-15. PMID:7349757. |
the mean alpha/beta total activity ratio in individuals with hb h disease was 0.51 (+/- 0.08), in heterozygous alpha thal1 0.74 (+/- 0.06), and in heterozygous alpha thal2 0.86 (+/- 0.06). |
1983-04-15 |
2023-08-12 |
Not clear |
| G Efremov, N Stojanovski, B Nastev, C Zisovsk. [Alpha thalassemia in Macedonia]. Bilten za hematologiju i transfuziju. vol 9. issue 1-3. 1983-04-15. PMID:7349757. |
these results support previously published data that in hb h disease and alpha thalassemia trait, there is quantitative deficit in alpha globin mrnk, which is a consequence of deleted alpha globin genes. |
1983-04-15 |
2023-08-12 |
Not clear |
| T Nakatsuji, H Lam, J B Wilson, B B Webber, T H Huisma. Hb F-Columbus-Ga or alpha 2 G gamma 2 94(FGl) Asp replaced by Asn. Hemoglobin. vol 6. issue 6. 1983-04-07. PMID:6186636. |
hb f-columbus-ga or alpha 2 g gamma 2 94(fgl) asp replaced by asn. |
1983-04-07 |
2023-08-12 |
Not clear |
| T Nakatsuji, M Headlee, H Lam, J B Wilson, T H Huisma. Hb F-Bonaire-Ga or alpha 2 A gamma 2 39(C5) Gln replaced by Arg, characterized by high pressure liquid chromatographic and microsequencing procedures. Hemoglobin. vol 6. issue 6. 1983-04-07. PMID:6186637. |
hb f-bonaire-ga or alpha 2 a gamma 2 39(c5) gln replaced by arg, characterized by high pressure liquid chromatographic and microsequencing procedures. |
1983-04-07 |
2023-08-12 |
Not clear |
| D Barra, R Petruzzelli, F Bossa, M Brunor. Primary structure of hemoglobin from trout (Salmo irideus) amino acid sequence of the beta chain of trout Hb I. Biochimica et biophysica acta. vol 742. issue 1. 1983-04-07. PMID:6824687. |
the amino acid sequence of the beta chain of trout hb i is presented; it adds to the previously reported sequence of the alpha chain (bossa et al. |
1983-04-07 |
2023-08-12 |
human |
| T Harano, K Harano, S Shibata, S Ueda, Y Nakashima, K Imai, M Sek. Hemoglobin variant with slight instability and increased oxygen affinity, Hb Etobicoke [alpha 84 (F5) Ser replaced by Arg]: the first case detected in Japan. Hemoglobin. vol 6. issue 6. 1983-04-07. PMID:6926746. |
hemoglobin variant with slight instability and increased oxygen affinity, hb etobicoke [alpha 84 (f5) ser replaced by arg]: the first case detected in japan. |
1983-04-07 |
2023-08-12 |
Not clear |
| C Romero, A Muñoz, I Fernández Fuertes, M Hernández-Jodra, J L Navarr. First association in Spain of Hb J Baltimore alpha A2 beta 2 16 (A13) Gly replaced by Asp and beta o thalassemia. Hemoglobin. vol 6. issue 6. 1983-04-07. PMID:7161107. |
first association in spain of hb j baltimore alpha a2 beta 2 16 (a13) gly replaced by asp and beta o thalassemia. |
1983-04-07 |
2023-08-12 |
Not clear |
| Y T Zeng, S Z Huang, X D Zhou, X K Qiu, Q Y Dong, M Y Li, J H Ba. Hb Shenyang (alpha 26 (B7) Ala replaced by Glu): a new unstable variant found in China. Hemoglobin. vol 6. issue 6. 1983-04-07. PMID:7161109. |
hb shenyang (alpha 26 (b7) ala replaced by glu): a new unstable variant found in china. |
1983-04-07 |
2023-08-12 |
Not clear |
| M A Zago, F F Costa, C Bottur. Thalassaemia intermedia in a family with beta 0-thalassaemia and Hb Hasharon. Journal of medical genetics. vol 19. issue 6. 1983-03-17. PMID:7154040. |
a brazilian family of italian descent is described in which the beta-thalassaemia gene is interacting with an alpha chain variant hb hasharon (alpha 47 asp leads to his). |
1983-03-17 |
2023-08-12 |
Not clear |
| M A Zago, F F Costa, C Bottur. Thalassaemia intermedia in a family with beta 0-thalassaemia and Hb Hasharon. Journal of medical genetics. vol 19. issue 6. 1983-03-17. PMID:7154040. |
her haemolysate contained 8.6% hb f hasharon (alpha 2 hasharon gamma 2) and 1.1% hb a2, the remaining haemoglobin being hb f. hb a was not detected. |
1983-03-17 |
2023-08-12 |
Not clear |