| Publication |
Sentence |
Publish Date |
Extraction Date |
Species |
| T Nakatsuji, J B Wilson, T H Huisma. Hb Cordele alpha(2)47 (CE5)Asp----Ala beta 2. A mildly unstable variant observed in black twins. Hemoglobin. vol 8. issue 1. 1984-06-25. PMID:6547117. |
hb cordele, which has an asp----ala substitution at position 47 (ce5) of the alpha chain, was discovered in black twins living in cordele, georgia. |
1984-06-25 |
2023-08-12 |
Not clear |
| T Nakatsuji, J B Wilson, T H Huisma. Hb Cordele alpha(2)47 (CE5)Asp----Ala beta 2. A mildly unstable variant observed in black twins. Hemoglobin. vol 8. issue 1. 1984-06-25. PMID:6547117. |
hb cordele has a normal oxygen affinity, but is mildly unstable at 60 degrees c. some of its properties have been compared with those of hb kokura (alpha 47 asp----gly), hb hasharon (alpha 47 asp----his), and hb arya (alpha 47 asp----asn). |
1984-06-25 |
2023-08-12 |
Not clear |
| J W Bender, M P Reilly, T Asakur. Molecular stability and function of hemoglobins Hasharon (alpha(2)47 (CD5)Asp----His beta 2) and Hasharon (alpha(2)47 (CD5)Asp----His delta 2). Hemoglobin. vol 8. issue 1. 1984-06-25. PMID:6724992. |
the molecular stability and function of hemoglobin (hb) hasharon (alpha 2 h beta 2) and hb hasharon2 (alpha 2 h delta 2) were studied and compared to hbs a, a2 and s. hb hasharon and hb hasharon2 had slightly lower p50 values than hb a and hb a2 but had normal responses to organic phosphates. |
1984-06-25 |
2023-08-12 |
Not clear |
| M D Rhoda, Y Blouquit, J Caburi-Martin, N Monplaisir, F Galacteros, M C Garel, J Ros. Effects of the alpha 20 mutation on the polymerization of Hb S. Biochimica et biophysica acta. vol 786. issue 1-2. 1984-06-18. PMID:6712958. |
effects of the alpha 20 mutation on the polymerization of hb s. the contribution of the alpha 20 residues in intermolecular contacts present in hemoglobin s fibers was investigated with mixtures of hb le lamentin alpha 2(20)his----gln beta 2a and of hemoglobin s alpha 2a beta 2(6)glu----val and with artificial hybrids alpha 2(20)his----gln beta 2(6)glu----val. |
1984-06-18 |
2023-08-12 |
Not clear |
| M D Rhoda, Y Blouquit, J Caburi-Martin, N Monplaisir, F Galacteros, M C Garel, J Ros. Effects of the alpha 20 mutation on the polymerization of Hb S. Biochimica et biophysica acta. vol 786. issue 1-2. 1984-06-18. PMID:6712958. |
this study showed an increased solubility and delay time of polymerization of hb s in solution only when the mutation at the alpha 20 residue is cis to the beta 6 val contact. |
1984-06-18 |
2023-08-12 |
Not clear |
| M D Rhoda, Y Blouquit, J Caburi-Martin, N Monplaisir, F Galacteros, M C Garel, J Ros. Effects of the alpha 20 mutation on the polymerization of Hb S. Biochimica et biophysica acta. vol 786. issue 1-2. 1984-06-18. PMID:6712958. |
this result is in agreement with the crystal model of wishner and love, who showed that one of the two alpha 20 residues of the hb s tetramer was involved in an axial contact between hemoglobin s molecules in the crystals of hb s ( wishner , b.c., ward, k.b., lattman , e.e. |
1984-06-18 |
2023-08-12 |
Not clear |
| T Harano, K Harano, S Shibata, S Ueda, H Mori, M Sek. Hemoglobin Aichi [alpha 50(CE8) His----Arg]: a new slightly unstable hemoglobin variant discovered in Japan. FEBS letters. vol 169. issue 2. 1984-06-13. PMID:6714429. |
a new abnormal hemoglobin, hb aichi [alpha 50(ce8) his----arg], was discovered in a young japanese man. |
1984-06-13 |
2023-08-12 |
Not clear |
| R Galanello, L Maccioni, M C Rosatelli, P Ibba, A M Nurchi, A Ca. A genetic combination of silent beta-thalassaemia, high Hb A2 beta-thalassaemia, and single alpha globin gene deletion causing mild thalassaemia intermedia. Journal of medical genetics. vol 21. issue 2. 1984-06-12. PMID:6716419. |
a genetic combination of silent beta-thalassaemia, high hb a2 beta-thalassaemia, and single alpha globin gene deletion causing mild thalassaemia intermedia. |
1984-06-12 |
2023-08-12 |
Not clear |
| R Galanello, L Maccioni, M C Rosatelli, P Ibba, A M Nurchi, A Ca. A genetic combination of silent beta-thalassaemia, high Hb A2 beta-thalassaemia, and single alpha globin gene deletion causing mild thalassaemia intermedia. Journal of medical genetics. vol 21. issue 2. 1984-06-12. PMID:6716419. |
this paper reports a sardinian patient, who was a compound heterozygote for silent beta-thalassaemia and high hb a2 beta o-thalassaemia with the clinical phenotype of mild thalassaemia intermedia; alpha globin gene mapping showed a single alpha globin gene deletion. |
1984-06-12 |
2023-08-12 |
Not clear |
| M Nagai, Y Yoneyam. Enzymatic reduction of hemoglobins M. Biomedica biochimica acta. vol 42. issue 11-12. 1984-06-06. PMID:6675686. |
these three enzymatic reduction systems did not reduce hbs m with an alpha chain anomaly such as hb m iwate and hb m boston. |
1984-06-06 |
2023-08-12 |
human |
| C S Johnson, W A Schroeder, J B Shelton, J R Shelto. The first example of a deletion in the human alpha chain: hemoglobin Boyle Heights or alpha 2 6 (A4) Asp----to O beta 2. Hemoglobin. vol 7. issue 2. 1984-05-14. PMID:6671902. |
like hb sawara (alpha 6 asp leads to ala), hb boyle heights has increased oxygen affinity. |
1984-05-14 |
2023-08-12 |
human |
| C S Johnson, W A Schroeder, J B Shelton, J R Shelto. The first example of a deletion in the human alpha chain: hemoglobin Boyle Heights or alpha 2 6 (A4) Asp----to O beta 2. Hemoglobin. vol 7. issue 2. 1984-05-14. PMID:6671902. |
it is likely that the bohr effect will be altered because the deletion in hb boyle heights should alter the configuration of val alpha 1 and influence its participation in the bohr effect. |
1984-05-14 |
2023-08-12 |
human |
| T Harano, K Harano, S Shibata, S Ueda, K Imai, A Tsuneshige, E Uchida, K Horiuch. Hb Le Lamentin [alpha 20 (B 1) His----Gln] in Japan: structure, function and biosynthesis. Hemoglobin. vol 7. issue 2. 1984-05-14. PMID:6671903. |
hb le lamentin [alpha 20 (b 1) his----gln] in japan: structure, function and biosynthesis. |
1984-05-14 |
2023-08-12 |
Not clear |
| P Bogoevski, G D Efremov, J Kezic, H Lam, J B Wilson, T H Huisma. Hb Sabine or alpha 2 beta 2 91 (F7) Leu----Pro in a Yugoslavian boy. Hemoglobin. vol 7. issue 2. 1984-05-14. PMID:6671906. |
hb sabine or alpha 2 beta 2 91 (f7) leu----pro in a yugoslavian boy. |
1984-05-14 |
2023-08-12 |
Not clear |
| R J Trent, M G Harris, P J Fleming, K Wyatt, W G Hughes, H Kronenber. Haemoglobin D Punjab. Interaction with alpha thalassaemia and diagnosis by gene mapping. Scandinavian journal of haematology. vol 32. issue 3. 1984-04-25. PMID:6322284. |
a family which illustrates the inheritance of hb d punjab (a beta globin chain variant) and alpha thalassaemia is described. |
1984-04-25 |
2023-08-12 |
Not clear |
| R J Trent, M G Harris, P J Fleming, K Wyatt, W G Hughes, H Kronenber. Haemoglobin D Punjab. Interaction with alpha thalassaemia and diagnosis by gene mapping. Scandinavian journal of haematology. vol 32. issue 3. 1984-04-25. PMID:6322284. |
interaction between hb d punjab and alpha thalassaemia is observed since levels of hb d vary according to the number of alpha globin genes deleted. |
1984-04-25 |
2023-08-12 |
Not clear |
| R J Trent, M G Harris, P J Fleming, K Wyatt, W G Hughes, H Kronenber. Haemoglobin D Punjab. Interaction with alpha thalassaemia and diagnosis by gene mapping. Scandinavian journal of haematology. vol 32. issue 3. 1984-04-25. PMID:6322284. |
the technique of gene mapping has been utilised in the current study to provide definitive evidence of alpha thalassaemia and also demonstrates a novel way to identify hb d punjab. |
1984-04-25 |
2023-08-12 |
Not clear |
| J Rochette, B Varet, J P Boissel, K Clough, D Labie, H Wajcman, B Bohn, P Magne, C Poyar. Structure and function of Hb Saint-Jacques (alpha 2 beta 2 140 (H18) Ala----Thr): a new high-oxygen-affinity variant with altered bisphosphoglycerate binding. Biochimica et biophysica acta. vol 785. issue 1-2. 1984-04-17. PMID:6546525. |
structure and function of hb saint-jacques (alpha 2 beta 2 140 (h18) ala----thr): a new high-oxygen-affinity variant with altered bisphosphoglycerate binding. |
1984-04-17 |
2023-08-12 |
Not clear |
| R T Francis, R R Becke. Two hemoglobin-binding proteins identified in the plasma of the amphibian Taricha granulosa. Comparative biochemistry and physiology. B, Comparative biochemistry. vol 77. issue 2. 1984-04-16. PMID:6697692. |
taricha hemoglobin not only failed to dissociate into alpha beta dimers as did human hb, but formed alpha beta octamers. |
1984-04-16 |
2023-08-12 |
human |
| R Galanello, M A Melis, L Maccioni, M Pirastu, A Ca. Longitudinal study of a newborn with a combination of deletion and nondeletion alpha-thalassemia-2. Pediatric research. vol 18. issue 2. 1984-04-11. PMID:6322098. |
because the deletion of one, two, or three alpha-globin structural genes is associated with 1-2%, 5-6%, or 25%, hb bart's respectively, these findings suggest that the non-deletion chromosome [(alpha alpha)th] contains two alpha-globin structural genes that are less active than a single alpha gene (-alpha). |
1984-04-11 |
2023-08-12 |
Not clear |