| Publication |
Sentence |
Publish Date |
Extraction Date |
Species |
| S A Liebhaber, F E Cas. Locus assignment of alpha-globin structural mutations by hybrid-selected translation. The Journal of clinical investigation. vol 75. issue 1. 1985-02-21. PMID:2981252. |
we have used this technique to localize the two alpha-globin mutants, alpha 125pro (hb quong sze) and alpha 47his (hb hasharon), to the alpha 2 locus. |
1985-02-21 |
2023-08-11 |
human |
| Y Blouquit, N Arous, D Lena, J Delanoe-Garin, C Lacombe, J Bardakdjian, L Vovan, A Orsini, J Rosa, F Galactero. Hb Marseille [alpha 2 beta 2 N methionyl-2 (NA2) His----Pro]: a new beta chain variant having an extended N-terminus. FEBS letters. vol 178. issue 2. 1985-02-14. PMID:6548977. |
hb marseille [alpha 2 beta 2 n methionyl-2 (na2) his----pro]: a new beta chain variant having an extended n-terminus. |
1985-02-14 |
2023-08-12 |
Not clear |
| J R Shaeffer, M J McDonald, S M Turci, D M Dinda, H F Bun. Dimer-monomer dissociation of human hemoglobin A. The Journal of biological chemistry. vol 259. issue 23. 1985-01-10. PMID:6501305. |
isolated 3h-labeled human hemoglobin alpha chains were incubated with unlabeled carbonmonoxyhemoglobin a for 72 h in 0.01 m potassium phosphate, ph 7.0, at 25 degrees c. following separation of the free alpha chain monomers and hb a (alpha 2 beta 2) tetramers by electrophoresis on cellulose acetate strips or by chromatography on deae-cellulose columns, analysis of radioactivity showed a slow transfer of 3h-labeled alpha chains into hb a. |
1985-01-10 |
2023-08-12 |
human |
| J R Shaeffer, M J McDonald, S M Turci, D M Dinda, H F Bun. Dimer-monomer dissociation of human hemoglobin A. The Journal of biological chemistry. vol 259. issue 23. 1985-01-10. PMID:6501305. |
separation of the globin chains of the isolated [3h] hb a on a cm-cellulose column in 8 m urea showed that the radioactivity was in structurally intact alpha chains. |
1985-01-10 |
2023-08-12 |
human |
| J R Shaeffer, M J McDonald, S M Turci, D M Dinda, H F Bun. Dimer-monomer dissociation of human hemoglobin A. The Journal of biological chemistry. vol 259. issue 23. 1985-01-10. PMID:6501305. |
these results indicate that the free 3h-labeled alpha chain monomers were incorporated into hb a by exchange with pre-existing unlabeled alpha chain subunits according to the scheme, alpha 2 beta 2 in equilibrium 2 alpha beta in equilibrium 2 alpha + 2 beta. |
1985-01-10 |
2023-08-12 |
human |
| R A Stinso. Asymmetric hybrids formed with hemoglobin British Columbia (alpha 2 beta 2101Glu----Lys). Hemoglobin. vol 8. issue 5. 1985-01-09. PMID:6500987. |
thus, the single hb recovered from agarose is probably the asymmetric hybrid alpha 2 delta beta british columbia. |
1985-01-09 |
2023-08-12 |
Not clear |
| L Maccioni, R Galanello, M A Melis, A Ca. Hemoglobin constitution of double heterozygotes for alpha or beta-thalassemia and Hb J Sardegna. Hemoglobin. vol 8. issue 5. 1985-01-09. PMID:6548732. |
hemoglobin constitution of double heterozygotes for alpha or beta-thalassemia and hb j sardegna. |
1985-01-09 |
2023-08-12 |
Not clear |
| L Maccioni, R Galanello, M A Melis, A Ca. Hemoglobin constitution of double heterozygotes for alpha or beta-thalassemia and Hb J Sardegna. Hemoglobin. vol 8. issue 5. 1985-01-09. PMID:6548732. |
then, we correlated the hb pattern with the alpha and beta-globin genotype. |
1985-01-09 |
2023-08-12 |
Not clear |
| L Maccioni, R Galanello, M A Melis, A Ca. Hemoglobin constitution of double heterozygotes for alpha or beta-thalassemia and Hb J Sardegna. Hemoglobin. vol 8. issue 5. 1985-01-09. PMID:6548732. |
in heterozygotes for hb j sardegna with a deletion of a single alpha-globin gene (alpha alpha/-alpha) the amount of the abnormal hb was significantly (p much less than 0.001) higher than in heterozygotes for this variant with a full complement of 4 alpha-globin structural genes (27.5% versus 20.4%). |
1985-01-09 |
2023-08-12 |
Not clear |
| H H Knox-Macaulay, A F Fleming, J Lamb, E C Mb. Haemoglobin GPhiladelphia and its interaction with haemoglobin S and alpha-thalassaemia in Nigerians. Clinical and laboratory haematology. vol 6. issue 2. 1984-12-18. PMID:6488738. |
in one of the families, fingerprints of the globin peptides and amino acid analysis confirmed that the mutant haemoglobin was hb gphiladelphia (alpha 2 68 asn----lys beta 2 a). |
1984-12-18 |
2023-08-12 |
Not clear |
| K Adachi, H Vonk, M P Reilly, H Adachi, W A Schroeder, E Schwartz, T Asakur. Relationship between tetramer-dimer assembly and the stability of Hb Malmö (alpha 2 beta 2 97Gln). Biochimica et biophysica acta. vol 790. issue 2. 1984-12-04. PMID:6487633. |
relationship between tetramer-dimer assembly and the stability of hb malmö (alpha 2 beta 2 97gln). |
1984-12-04 |
2023-08-12 |
Not clear |
| K Adachi, H Vonk, M P Reilly, H Adachi, W A Schroeder, E Schwartz, T Asakur. Relationship between tetramer-dimer assembly and the stability of Hb Malmö (alpha 2 beta 2 97Gln). Biochimica et biophysica acta. vol 790. issue 2. 1984-12-04. PMID:6487633. |
the effects of the mutation of the alpha 1 beta 2 contact in hb malmö (alpha 2 beta 2 97(fg4)his----gln) on oxygen-binding properties, ease of dissociation into dimeric hemoglobin and stability were studied. |
1984-12-04 |
2023-08-12 |
Not clear |
| K Adachi, H Vonk, M P Reilly, H Adachi, W A Schroeder, E Schwartz, T Asakur. Relationship between tetramer-dimer assembly and the stability of Hb Malmö (alpha 2 beta 2 97Gln). Biochimica et biophysica acta. vol 790. issue 2. 1984-12-04. PMID:6487633. |
the instability of hb malmö depends on a greater alpha 1 beta 2 dissociation constant compared with that of hb a. |
1984-12-04 |
2023-08-12 |
Not clear |
| I Iuchi, S Shimasaki, K Hidaka, W Mizut. Hb Albany-Suma (alpha 11 [A9] Lys----Asn), a hemoglobin variant with slightly elevated oxygen affinity in Japan. Hemoglobin. vol 8. issue 4. 1984-11-09. PMID:6434493. |
hb albany-suma (alpha 11 [a9] lys----asn), a hemoglobin variant with slightly elevated oxygen affinity in japan. |
1984-11-09 |
2023-08-12 |
Not clear |
| F Xiong, K G Yang, C C Liang, Y W Huang, R X Wang, N J Zhan. A case of Hb J-Camaguey or alpha 2141(HC3)Arg----Gly beta 2 in a Chinese family. Hemoglobin. vol 8. issue 4. 1984-11-09. PMID:6480361. |
a case of hb j-camaguey or alpha 2141(hc3)arg----gly beta 2 in a chinese family. |
1984-11-09 |
2023-08-12 |
Not clear |
| R Galanello, L Maccioni, R Ruggeri, L Perseu, A Ca. Alpha thalassaemia in Sardinian newborns. British journal of haematology. vol 58. issue 2. 1984-11-09. PMID:6548148. |
infants with two alpha-globin genes deleted (- alpha/- alpha and --/ alpha alpha genotypes) had microcytosis, low mch and hb bart's in the 2.0-7.1% range. |
1984-11-09 |
2023-08-12 |
Not clear |
| R Galanello, L Maccioni, R Ruggeri, L Perseu, A Ca. Alpha thalassaemia in Sardinian newborns. British journal of haematology. vol 58. issue 2. 1984-11-09. PMID:6548148. |
a minority (38.9%) of infants with the (- alpha/ alpha alpha) globin genotype had detectable hb bart's, in the 0.78-2.5% range, frequently associated with minimal microcytosis while the remainder (61.1%) were completely silent. |
1984-11-09 |
2023-08-12 |
Not clear |
| R Galanello, L Maccioni, R Ruggeri, L Perseu, A Ca. Alpha thalassaemia in Sardinian newborns. British journal of haematology. vol 58. issue 2. 1984-11-09. PMID:6548148. |
infants carriers of a non-deletion type of alpha-thalassaemia showed hb bart's levels within the range found in the (- alpha / alpha alpha) genotype. |
1984-11-09 |
2023-08-12 |
Not clear |
| H J Li, D X Liu, Z G Liu, P Li, L Li, J Chen, S Z Ho. A new fast-moving hemoglobin variant, Hb J-Tashikuergan alpha 19(AB1) Ala----Glu. Hemoglobin. vol 8. issue 4. 1984-11-09. PMID:6548207. |
a new fast-moving hemoglobin variant, hb j-tashikuergan alpha 19(ab1) ala----glu. |
1984-11-09 |
2023-08-12 |
Not clear |
| S Miura, C H. Proton nuclear magnetic resonance investigation of cross-linked asymmetrically modified hemoglobins: influence of the salt bridges on tertiary and quaternary structures of hemoglobin. Biochemistry. vol 23. issue 11. 1984-11-02. PMID:6477880. |
asymmetrically modified hemoglobins, [alpha(des-arg)beta]a[alpha beta]cxl, [alpha(des-arg-tyr)beta]a[alpha beta]cxl, [alpha(des-arg)beta(nes)]a[alpha beta]cxl, and [alpha(des-arg)beta]a[alpha beta(nes)]cxl, have been prepared from chemically modified human normal adult hemoglobin (hb a) and mutant hemoglobin c (beta 6glu----lys), where the subscript a or c denotes that the alpha beta dimer is from either hb a or hb c, respectively, and xl symbolizes a cross-linked hemoglobin prepared by reaction with a bifunctional cross-linking reagent, bis(3,5-dibromosalicyl) fumarate. |
1984-11-02 |
2023-08-12 |
human |