| Publication |
Sentence |
Publish Date |
Extraction Date |
Species |
| L E Lie-Injo, A R Herrera, R V Lebo, K Hassan, C G Lope. Gene mapping of Malaysian alpha thalassemias with alpha and zeta globin gene probes. American journal of hematology. vol 18. issue 3. 1985-04-04. PMID:2983536. |
restriction enzyme analysis of the alpha and zeta globin genes was carried out in four cases of hb bart's hydrops fetalis, in three patients with hb h disease without hb cosp, in three patients with hb h disease with hb cosp, in 47 individuals with alpha thalassemia trait, and in 47 normal individuals. |
1985-04-04 |
2023-08-11 |
Not clear |
| L E Lie-Injo, A R Herrera, R V Lebo, K Hassan, C G Lope. Gene mapping of Malaysian alpha thalassemias with alpha and zeta globin gene probes. American journal of hematology. vol 18. issue 3. 1985-04-04. PMID:2983536. |
all four cases of hb bart's hydrops fetalis resulted from deletions of alpha 1 and alpha 2 globin genes which did not extend to the psi zeta 1 and zeta 2 globin genes. |
1985-04-04 |
2023-08-11 |
Not clear |
| L E Lie-Injo, A R Herrera, R V Lebo, K Hassan, C G Lope. Gene mapping of Malaysian alpha thalassemias with alpha and zeta globin gene probes. American journal of hematology. vol 18. issue 3. 1985-04-04. PMID:2983536. |
on another front, bgl ii restriction analysis of all four hb bart's hydrops fetalis cases and the alpha thal1 trait carriers showed a 10.5-kb bgl ii restriction fragment, in the hydrops fetalis as a single band, while in the carriers this 10.5-kb fragment was accompanied by the usual normal 12.5-kb and 11.3-kb fragments. |
1985-04-04 |
2023-08-11 |
Not clear |
| S Shimasak. A new hemoglobin variant, hemoglobin Nunobiki [alpha 141 (HC3) Arg----Cys]. Notable influence of the carboxy-terminal cysteine upon various physico-chemical characteristics of hemoglobin. The Journal of clinical investigation. vol 75. issue 2. 1985-04-03. PMID:3973024. |
cysteinyl residue at alpha 141 in hb nunobiki did not seem to be involved in the formation of either intermolecular or intramolecular disulfide bonds under physiologic conditions. |
1985-04-03 |
2023-08-11 |
Not clear |
| R J Trent, J Yakas, P E Brock, H Kronenber. The molecular and hematological heterogeneity of alpha thalassemia. Australian and New Zealand journal of medicine. vol 14. issue 5. 1985-03-25. PMID:6099115. |
in contrast, hb bart's (gamma 4) is a useful marker for alpha alpha/-alpha in cord blood samples. |
1985-03-25 |
2023-08-12 |
Not clear |
| S A Liebhaber, F E Cas. Locus assignment of alpha-globin structural mutations by hybrid-selected translation. The Journal of clinical investigation. vol 75. issue 1. 1985-02-21. PMID:2981252. |
we have used this technique to localize the two alpha-globin mutants, alpha 125pro (hb quong sze) and alpha 47his (hb hasharon), to the alpha 2 locus. |
1985-02-21 |
2023-08-11 |
human |
| Y Blouquit, N Arous, D Lena, J Delanoe-Garin, C Lacombe, J Bardakdjian, L Vovan, A Orsini, J Rosa, F Galactero. Hb Marseille [alpha 2 beta 2 N methionyl-2 (NA2) His----Pro]: a new beta chain variant having an extended N-terminus. FEBS letters. vol 178. issue 2. 1985-02-14. PMID:6548977. |
hb marseille [alpha 2 beta 2 n methionyl-2 (na2) his----pro]: a new beta chain variant having an extended n-terminus. |
1985-02-14 |
2023-08-12 |
Not clear |
| J R Shaeffer, M J McDonald, S M Turci, D M Dinda, H F Bun. Dimer-monomer dissociation of human hemoglobin A. The Journal of biological chemistry. vol 259. issue 23. 1985-01-10. PMID:6501305. |
isolated 3h-labeled human hemoglobin alpha chains were incubated with unlabeled carbonmonoxyhemoglobin a for 72 h in 0.01 m potassium phosphate, ph 7.0, at 25 degrees c. following separation of the free alpha chain monomers and hb a (alpha 2 beta 2) tetramers by electrophoresis on cellulose acetate strips or by chromatography on deae-cellulose columns, analysis of radioactivity showed a slow transfer of 3h-labeled alpha chains into hb a. |
1985-01-10 |
2023-08-12 |
human |
| J R Shaeffer, M J McDonald, S M Turci, D M Dinda, H F Bun. Dimer-monomer dissociation of human hemoglobin A. The Journal of biological chemistry. vol 259. issue 23. 1985-01-10. PMID:6501305. |
separation of the globin chains of the isolated [3h] hb a on a cm-cellulose column in 8 m urea showed that the radioactivity was in structurally intact alpha chains. |
1985-01-10 |
2023-08-12 |
human |
| J R Shaeffer, M J McDonald, S M Turci, D M Dinda, H F Bun. Dimer-monomer dissociation of human hemoglobin A. The Journal of biological chemistry. vol 259. issue 23. 1985-01-10. PMID:6501305. |
these results indicate that the free 3h-labeled alpha chain monomers were incorporated into hb a by exchange with pre-existing unlabeled alpha chain subunits according to the scheme, alpha 2 beta 2 in equilibrium 2 alpha beta in equilibrium 2 alpha + 2 beta. |
1985-01-10 |
2023-08-12 |
human |
| R A Stinso. Asymmetric hybrids formed with hemoglobin British Columbia (alpha 2 beta 2101Glu----Lys). Hemoglobin. vol 8. issue 5. 1985-01-09. PMID:6500987. |
thus, the single hb recovered from agarose is probably the asymmetric hybrid alpha 2 delta beta british columbia. |
1985-01-09 |
2023-08-12 |
Not clear |
| L Maccioni, R Galanello, M A Melis, A Ca. Hemoglobin constitution of double heterozygotes for alpha or beta-thalassemia and Hb J Sardegna. Hemoglobin. vol 8. issue 5. 1985-01-09. PMID:6548732. |
hemoglobin constitution of double heterozygotes for alpha or beta-thalassemia and hb j sardegna. |
1985-01-09 |
2023-08-12 |
Not clear |
| L Maccioni, R Galanello, M A Melis, A Ca. Hemoglobin constitution of double heterozygotes for alpha or beta-thalassemia and Hb J Sardegna. Hemoglobin. vol 8. issue 5. 1985-01-09. PMID:6548732. |
then, we correlated the hb pattern with the alpha and beta-globin genotype. |
1985-01-09 |
2023-08-12 |
Not clear |
| L Maccioni, R Galanello, M A Melis, A Ca. Hemoglobin constitution of double heterozygotes for alpha or beta-thalassemia and Hb J Sardegna. Hemoglobin. vol 8. issue 5. 1985-01-09. PMID:6548732. |
in heterozygotes for hb j sardegna with a deletion of a single alpha-globin gene (alpha alpha/-alpha) the amount of the abnormal hb was significantly (p much less than 0.001) higher than in heterozygotes for this variant with a full complement of 4 alpha-globin structural genes (27.5% versus 20.4%). |
1985-01-09 |
2023-08-12 |
Not clear |
| H H Knox-Macaulay, A F Fleming, J Lamb, E C Mb. Haemoglobin GPhiladelphia and its interaction with haemoglobin S and alpha-thalassaemia in Nigerians. Clinical and laboratory haematology. vol 6. issue 2. 1984-12-18. PMID:6488738. |
in one of the families, fingerprints of the globin peptides and amino acid analysis confirmed that the mutant haemoglobin was hb gphiladelphia (alpha 2 68 asn----lys beta 2 a). |
1984-12-18 |
2023-08-12 |
Not clear |
| K Adachi, H Vonk, M P Reilly, H Adachi, W A Schroeder, E Schwartz, T Asakur. Relationship between tetramer-dimer assembly and the stability of Hb Malmö (alpha 2 beta 2 97Gln). Biochimica et biophysica acta. vol 790. issue 2. 1984-12-04. PMID:6487633. |
relationship between tetramer-dimer assembly and the stability of hb malmö (alpha 2 beta 2 97gln). |
1984-12-04 |
2023-08-12 |
Not clear |
| K Adachi, H Vonk, M P Reilly, H Adachi, W A Schroeder, E Schwartz, T Asakur. Relationship between tetramer-dimer assembly and the stability of Hb Malmö (alpha 2 beta 2 97Gln). Biochimica et biophysica acta. vol 790. issue 2. 1984-12-04. PMID:6487633. |
the effects of the mutation of the alpha 1 beta 2 contact in hb malmö (alpha 2 beta 2 97(fg4)his----gln) on oxygen-binding properties, ease of dissociation into dimeric hemoglobin and stability were studied. |
1984-12-04 |
2023-08-12 |
Not clear |
| K Adachi, H Vonk, M P Reilly, H Adachi, W A Schroeder, E Schwartz, T Asakur. Relationship between tetramer-dimer assembly and the stability of Hb Malmö (alpha 2 beta 2 97Gln). Biochimica et biophysica acta. vol 790. issue 2. 1984-12-04. PMID:6487633. |
the instability of hb malmö depends on a greater alpha 1 beta 2 dissociation constant compared with that of hb a. |
1984-12-04 |
2023-08-12 |
Not clear |
| I Iuchi, S Shimasaki, K Hidaka, W Mizut. Hb Albany-Suma (alpha 11 [A9] Lys----Asn), a hemoglobin variant with slightly elevated oxygen affinity in Japan. Hemoglobin. vol 8. issue 4. 1984-11-09. PMID:6434493. |
hb albany-suma (alpha 11 [a9] lys----asn), a hemoglobin variant with slightly elevated oxygen affinity in japan. |
1984-11-09 |
2023-08-12 |
Not clear |
| F Xiong, K G Yang, C C Liang, Y W Huang, R X Wang, N J Zhan. A case of Hb J-Camaguey or alpha 2141(HC3)Arg----Gly beta 2 in a Chinese family. Hemoglobin. vol 8. issue 4. 1984-11-09. PMID:6480361. |
a case of hb j-camaguey or alpha 2141(hc3)arg----gly beta 2 in a chinese family. |
1984-11-09 |
2023-08-12 |
Not clear |