Publication |
Sentence |
Publish Date |
Extraction Date |
Species |
J G Chang, T C Liu, L I Perng, S S Chiou, T P Chen, P H Chen, C P Li. Rapid molecular characterization of Hb H disease in Chinese by polymerase chain reaction. Annals of hematology. vol 68. issue 1. 1994-03-29. PMID:8110877. |
one hundred and one cases of hb h disease from different families were studied: all of the cases had one allele of --sea deletion, while the other allele showed that 52/101 were -alpha 3.7, 41/101 were alpha cs alpha, 7/101 were -alpha 4.2, and 1/101 was -alpha g. taichung. |
1994-03-29 |
2023-08-12 |
Not clear |
R Motterlini, V W Macdonal. Cell-free hemoglobin potentiates acetylcholine-induced coronary vasoconstriction in rabbit hearts. Journal of applied physiology (Bethesda, Md. : 1985). vol 75. issue 5. 1994-03-17. PMID:7508430. |
we investigated the effects of human hb interdimerically cross-linked with bis-(3,5-dibromosalicyl)fumarate (alpha alpha hb) on the coronary vasomotor response to acetylcholine (ach) in isolated perfused rabbit hearts. |
1994-03-17 |
2023-08-12 |
human |
R Motterlini, V W Macdonal. Cell-free hemoglobin potentiates acetylcholine-induced coronary vasoconstriction in rabbit hearts. Journal of applied physiology (Bethesda, Md. : 1985). vol 75. issue 5. 1994-03-17. PMID:7508430. |
infusion of 0.1 g/dl alpha alpha hb altered the dose-dependent response to ach, decreasing the calculated ic50 (ach concn at which coronary pressure is 50% of its maximal value) from 3.96 +/- 0.34 to 0.85 +/- 0.06 microm (p < 0.01). |
1994-03-17 |
2023-08-12 |
human |
R Motterlini, V W Macdonal. Cell-free hemoglobin potentiates acetylcholine-induced coronary vasoconstriction in rabbit hearts. Journal of applied physiology (Bethesda, Md. : 1985). vol 75. issue 5. 1994-03-17. PMID:7508430. |
this augmented sensitivity to ach was only partially reversed upon washout of alpha alpha hb (ic50 1.93 +/- 0.13 microm). |
1994-03-17 |
2023-08-12 |
human |
R Motterlini, V W Macdonal. Cell-free hemoglobin potentiates acetylcholine-induced coronary vasoconstriction in rabbit hearts. Journal of applied physiology (Bethesda, Md. : 1985). vol 75. issue 5. 1994-03-17. PMID:7508430. |
simultaneous infusion of 60 microm deferoxamine mesylate with alpha alpha hb attenuated this response (ic50 decreased from 3.86 +/- 0.27 to 1.73 +/- 0.38 microm), which was completely reversed after removal of alpha alpha hb (ic50 3.41 +/- 0.17 microm). |
1994-03-17 |
2023-08-12 |
human |
R Motterlini, V W Macdonal. Cell-free hemoglobin potentiates acetylcholine-induced coronary vasoconstriction in rabbit hearts. Journal of applied physiology (Bethesda, Md. : 1985). vol 75. issue 5. 1994-03-17. PMID:7508430. |
ng-nitro-l-arginine methyl ester (50 microm) and cross-linked cyanomethemoglobin (cnmet alpha alpha hb, 0.1 g/dl) induced a significant (p < 0.05) increase in ach-induced vasoconstriction accompanied by a reduction in myocardial functions in the same range as that caused by alpha alpha hb. |
1994-03-17 |
2023-08-12 |
human |
R Motterlini, V W Macdonal. Cell-free hemoglobin potentiates acetylcholine-induced coronary vasoconstriction in rabbit hearts. Journal of applied physiology (Bethesda, Md. : 1985). vol 75. issue 5. 1994-03-17. PMID:7508430. |
infusion of deferoxamine mesylate (60 microm) with cnmet alpha alpha hb completely prevented the reduction in ic50 elicited by the infusion of cnmet alpha alpha hb alone. |
1994-03-17 |
2023-08-12 |
human |
R Motterlini, V W Macdonal. Cell-free hemoglobin potentiates acetylcholine-induced coronary vasoconstriction in rabbit hearts. Journal of applied physiology (Bethesda, Md. : 1985). vol 75. issue 5. 1994-03-17. PMID:7508430. |
these data demonstrate that alpha alpha hb can alter coronary vasomotor responsiveness and suggest the involvement of at least two mechanisms, one that is related to an accessible ferrous heme and is reversible and another that does not require an open heme site and is irreversible. |
1994-03-17 |
2023-08-12 |
human |
J Svasti, R Surarit, C Srisomsap, P Pravatmuang, P Wasi, S Fucharoen, Y Blouquit, F Galacteros, J Ros. Identification of Hb Anantharaj [alpha 11(A9)Lys->Glu] as Hb J-Wenchang-Wuming [alpha 11(A9)Lys->Gln]. Hemoglobin. vol 17. issue 5. 1994-02-25. PMID:7904985. |
identification of hb anantharaj [alpha 11(a9)lys->glu] as hb j-wenchang-wuming [alpha 11(a9)lys->gln]. |
1994-02-25 |
2023-08-12 |
Not clear |
H Wajcman, G Kalmès, P Groff, D Promé, J Riou, F Galactero. Hb Melusine [alpha 114(GH2)Pro-->Ser]: a new neutral hemoglobin variant. Hemoglobin. vol 17. issue 5. 1994-02-25. PMID:8294199. |
hb melusine [alpha 114(gh2)pro-->ser]: a new neutral hemoglobin variant. |
1994-02-25 |
2023-08-12 |
Not clear |
H Wajcman, G Kalmès, P Groff, D Promé, J Riou, F Galactero. Hb Melusine [alpha 114(GH2)Pro-->Ser]: a new neutral hemoglobin variant. Hemoglobin. vol 17. issue 5. 1994-02-25. PMID:8294199. |
hb melusine [alpha 114(gh2)pro-->ser] was found in an algerian patient during a systematic screening for hemoglobinopathies performed in luxembourg. |
1994-02-25 |
2023-08-12 |
Not clear |
H Wajcman, G Kalmès, P Groff, D Promé, J Riou, F Galactero. Hb Melusine [alpha 114(GH2)Pro-->Ser]: a new neutral hemoglobin variant. Hemoglobin. vol 17. issue 5. 1994-02-25. PMID:8294199. |
the structural abnormality of hb melusine concerns position alpha 114(gh2) that belongs to a cluster of hydrophobic residues localized in the n-terminal half of the alpha t-12b tryptic peptide. |
1994-02-25 |
2023-08-12 |
Not clear |
H Wajcman, G Kalmès, P Groff, D Promé, J Riou, F Galactero. Hb Melusine [alpha 114(GH2)Pro-->Ser]: a new neutral hemoglobin variant. Hemoglobin. vol 17. issue 5. 1994-02-25. PMID:8294199. |
it has been shown in the case of another variant of that position (hb nouakchott), that the replacement of the pro gh2 by a leu was responsible for a dramatic increase in the retention time of the alpha polypeptide chain during reversed phase high performance liquid chromatography, much higher than that reported for similar substitutions in other regions of the hemoglobin molecule. |
1994-02-25 |
2023-08-12 |
Not clear |
H Wajcman, J Kister, A M'Rad, M C Marden, J Riou, F Galactero. Hb Val de Marne [alpha 133(H16)Ser-->Arg]: a new hemoglobin variant with moderate increase in oxygen affinity. Hemoglobin. vol 17. issue 5. 1994-02-25. PMID:8294200. |
hb val de marne [alpha 133(h16)ser-->arg]: a new hemoglobin variant with moderate increase in oxygen affinity. |
1994-02-25 |
2023-08-12 |
Not clear |
H Wajcman, J Kister, A M'Rad, M C Marden, J Riou, F Galactero. Hb Val de Marne [alpha 133(H16)Ser-->Arg]: a new hemoglobin variant with moderate increase in oxygen affinity. Hemoglobin. vol 17. issue 5. 1994-02-25. PMID:8294200. |
hb val de marne [alpha 133(h16)ser-->arg] was found in a french family during a neonatal hemoglobinopathy screening program. |
1994-02-25 |
2023-08-12 |
Not clear |
Postnikov YuV, T P Molchanova, T H Huisma. Allele-specific amplification for the identification of several hemoglobin variants. Hemoglobin. vol 17. issue 5. 1994-02-25. PMID:8294203. |
these are mutants of the a gamma (hb f-sardinia), the delta (hb b2), the alpha (hb g-philadelphia), and the beta (hbs s, c, e, d-los angeles, o-arab) globin genes. |
1994-02-25 |
2023-08-12 |
Not clear |
J J Malcorra-Azpiazu, J B Wilson, T P Molchanova, D D Pobedimskaya, T H Huisma. Hb Porto Alegre or alpha 2 beta 29(A6)Ser->Cys in unrelated families of the Canary Islands. Hemoglobin. vol 17. issue 5. 1994-02-25. PMID:8294204. |
hb porto alegre or alpha 2 beta 29(a6)ser->cys in unrelated families of the canary islands. |
1994-02-25 |
2023-08-12 |
Not clear |
H Gilch, R Schweitzer-Stenner, W Dreybrod. Structural heterogeneity of the Fe(2+)-N epsilon (HisF8) bond in various hemoglobin and myoglobin derivatives probed by the Raman-active iron histidine stretching mode. Biophysical journal. vol 65. issue 4. 1994-02-04. PMID:8274641. |
moreover we have reanalyzed other raman bands from the literature, namely the nu fe-his band of the isolated hemoglobin subunits alpha sh- and beta sh-hba, various hemoglobin mutants (i.e., hb(tyrc7 alpha-->phe), hb(tyrc7 alpha-->his), hb m-boston and hb m-iwate), n-ethylmaleimide-des(arg141 alpha) hemoglobin (nes-des(arg141 alpha)hba) and photolyzed carbonmonoxide hemoglobin (hb*co) measured 25 ps and 10 ns after photolysis. |
1994-02-04 |
2023-08-12 |
Not clear |
H Gilch, R Schweitzer-Stenner, W Dreybrod. Structural heterogeneity of the Fe(2+)-N epsilon (HisF8) bond in various hemoglobin and myoglobin derivatives probed by the Raman-active iron histidine stretching mode. Biophysical journal. vol 65. issue 4. 1994-02-04. PMID:8274641. |
additional sublines were found to contribute to the nu fe-his band of nes-des(arg141 alpha) hba and the hb*co species. |
1994-02-04 |
2023-08-12 |
Not clear |
F Prouchayret, E Dellacheri. Low oxygen affinity derivatives of human hemoglobin by fixation of polycarboxylic dextran to the oxyform. Biopolymers. vol 33. issue 12. 1994-01-31. PMID:7505635. |
the chemical modification that has been the most studied during the last few years is the cross-linking of the protein between its two alpha beta dimers, in order, first, to hamper their diffusion through the kidney and therefore increase the plasma persistence of hb, and second, to decrease its oxygen affinity. |
1994-01-31 |
2023-08-12 |
human |