| Publication |
Sentence |
Publish Date |
Extraction Date |
Species |
| Kenji Kozuka, Ying He, Samantha Koo-McCoy, Padmapriya Kumaraswamy, Baoming Nie, Karen Shaw, Priscilla Chan, Michael Leadbetter, Limin He, Jason G Lewis, Ziyang Zhong, Dominique Charmot, Marwan Balaa, Andrew J King, Jeremy S Caldwell, Matthew Siege. Development and Characterization of a Human and Mouse Intestinal Epithelial Cell Monolayer Platform. Stem cell reports. vol 9. issue 6. 2018-07-17. PMID:29153987. |
the cultures secreted serotonin, glp-1, and fgf19 and upregulated the epithelial sodium channel in response to known biologically active agents, suggesting intact secretory and absorptive functions. |
2018-07-17 |
2023-08-13 |
mouse |
| Nuria Martinez-Saez, Christina Maria Hochkogler, Veronika Somoza, Maria Dolores Del Castill. Biscuits with No Added Sugar Containing Stevia, Coffee Fibre and Fructooligosaccharides Modifies α-Glucosidase Activity and the Release of GLP-1 from HuTu-80 Cells and Serotonin from Caco-2 Cells after In Vitro Digestion. Nutrients. vol 9. issue 7. 2018-04-09. PMID:28677657. |
biscuits with no added sugar containing stevia, coffee fibre and fructooligosaccharides modifies α-glucosidase activity and the release of glp-1 from hutu-80 cells and serotonin from caco-2 cells after in vitro digestion. |
2018-04-09 |
2023-08-13 |
human |
| Dina Ripken, Nikkie van der Wielen, Heleen M Wortelboer, Jocelijn Meijerink, Renger F Witkamp, Henk F J Hendrik. Nutrient-induced glucagon like peptide-1 release is modulated by serotonin. The Journal of nutritional biochemistry. vol 32. 2017-10-09. PMID:27142747. |
glucagon like peptide-1 (glp-1) and serotonin are both involved in food intake regulation. |
2017-10-09 |
2023-08-13 |
Not clear |
| Dina Ripken, Nikkie van der Wielen, Heleen M Wortelboer, Jocelijn Meijerink, Renger F Witkamp, Henk F J Hendrik. Nutrient-induced glucagon like peptide-1 release is modulated by serotonin. The Journal of nutritional biochemistry. vol 32. 2017-10-09. PMID:27142747. |
glp-1 release is stimulated upon nutrient interaction with g-protein coupled receptors by enteroendocrine cells (eec), whereas serotonin is released from enterochromaffin cells (ecc). |
2017-10-09 |
2023-08-13 |
Not clear |
| Dina Ripken, Nikkie van der Wielen, Heleen M Wortelboer, Jocelijn Meijerink, Renger F Witkamp, Henk F J Hendrik. Nutrient-induced glucagon like peptide-1 release is modulated by serotonin. The Journal of nutritional biochemistry. vol 32. 2017-10-09. PMID:27142747. |
the central hypothesis for the current study was that nutrient-induced glp-1 release from eecs is modulated by serotonin through a process involving serotonin receptor interaction. |
2017-10-09 |
2023-08-13 |
Not clear |
| Dina Ripken, Nikkie van der Wielen, Heleen M Wortelboer, Jocelijn Meijerink, Renger F Witkamp, Henk F J Hendrik. Nutrient-induced glucagon like peptide-1 release is modulated by serotonin. The Journal of nutritional biochemistry. vol 32. 2017-10-09. PMID:27142747. |
this was studied by assessing the effects of serotonin reuptake inhibition by fluoxetine on nutrient-induced glp-1, pyy and cck release from isolated pig intestinal segments. |
2017-10-09 |
2023-08-13 |
Not clear |
| Dina Ripken, Nikkie van der Wielen, Heleen M Wortelboer, Jocelijn Meijerink, Renger F Witkamp, Henk F J Hendrik. Nutrient-induced glucagon like peptide-1 release is modulated by serotonin. The Journal of nutritional biochemistry. vol 32. 2017-10-09. PMID:27142747. |
exposure of ileal tissue segments to serotonin (30μm) stimulated glp-1 release whereas it did not induce pyy and cck release. |
2017-10-09 |
2023-08-13 |
Not clear |
| Dina Ripken, Nikkie van der Wielen, Heleen M Wortelboer, Jocelijn Meijerink, Renger F Witkamp, Henk F J Hendrik. Nutrient-induced glucagon like peptide-1 release is modulated by serotonin. The Journal of nutritional biochemistry. vol 32. 2017-10-09. PMID:27142747. |
serotonin (30 and 100μm) also stimulated glp-1 release from stc-1 cells, which was inhibited by the non-specific 5ht receptor antagonist asenapine (1 and 10μm). |
2017-10-09 |
2023-08-13 |
Not clear |
| Dina Ripken, Nikkie van der Wielen, Heleen M Wortelboer, Jocelijn Meijerink, Renger F Witkamp, Henk F J Hendrik. Nutrient-induced glucagon like peptide-1 release is modulated by serotonin. The Journal of nutritional biochemistry. vol 32. 2017-10-09. PMID:27142747. |
these data suggest that nutrient-induced glp-1 release is modulated by serotonin through a receptor mediated process. |
2017-10-09 |
2023-08-13 |
Not clear |
| Linda J Fothergill, Brid Callaghan, Billie Hunne, David M Bravo, John B Furnes. Costorage of Enteroendocrine Hormones Evaluated at the Cell and Subcellular Levels in Male Mice. Endocrinology. vol 158. issue 7. 2017-09-29. PMID:28430903. |
cga and 5-ht were frequently expressed in eecs that contained combinations of glp-1, ghrelin, secretin, and cck. |
2017-09-29 |
2023-08-13 |
mouse |
| Linda J Fothergill, Brid Callaghan, Billie Hunne, David M Bravo, John B Furnes. Costorage of Enteroendocrine Hormones Evaluated at the Cell and Subcellular Levels in Male Mice. Endocrinology. vol 158. issue 7. 2017-09-29. PMID:28430903. |
separate subcellular stores of 5-ht, cga, secretin, cck, ghrelin, and glp-1 were identified. |
2017-09-29 |
2023-08-13 |
mouse |
| Rozita H Anderberg, Jennifer E Richard, Kim Eerola, Lorena López-Ferreras, Elin Banke, Caroline Hansson, Hans Nissbrandt, Filip Berqquist, Fiona M Gribble, Frank Reimann, Ingrid Wernstedt Asterholm, Christophe M Lamy, Karolina P Skibick. Glucagon-Like Peptide 1 and Its Analogs Act in the Dorsal Raphe and Modulate Central Serotonin to Reduce Appetite and Body Weight. Diabetes. vol 66. issue 4. 2017-06-13. PMID:28057699. |
glucagon-like peptide 1 (glp-1) and serotonin play critical roles in energy balance regulation. |
2017-06-13 |
2023-08-13 |
rat |
| Rozita H Anderberg, Jennifer E Richard, Kim Eerola, Lorena López-Ferreras, Elin Banke, Caroline Hansson, Hans Nissbrandt, Filip Berqquist, Fiona M Gribble, Frank Reimann, Ingrid Wernstedt Asterholm, Christophe M Lamy, Karolina P Skibick. Glucagon-Like Peptide 1 and Its Analogs Act in the Dorsal Raphe and Modulate Central Serotonin to Reduce Appetite and Body Weight. Diabetes. vol 66. issue 4. 2017-06-13. PMID:28057699. |
here we investigated mechanisms by which glp-1 and serotonin interact at the level of the central nervous system. |
2017-06-13 |
2023-08-13 |
rat |
| Rozita H Anderberg, Jennifer E Richard, Kim Eerola, Lorena López-Ferreras, Elin Banke, Caroline Hansson, Hans Nissbrandt, Filip Berqquist, Fiona M Gribble, Frank Reimann, Ingrid Wernstedt Asterholm, Christophe M Lamy, Karolina P Skibick. Glucagon-Like Peptide 1 and Its Analogs Act in the Dorsal Raphe and Modulate Central Serotonin to Reduce Appetite and Body Weight. Diabetes. vol 66. issue 4. 2017-06-13. PMID:28057699. |
serotonin depletion impaired the ability of exendin-4, a clinically used glp-1 analog, to reduce body weight in rats, suggesting that serotonin is a critical mediator of the energy balance impact of glp-1 receptor (glp-1r) activation. |
2017-06-13 |
2023-08-13 |
rat |
| Patricia Martins, Josiane Fakhry, Enio Chaves de Oliveira, Billie Hunne, Linda J Fothergill, Mitchell Ringuet, Débora d'Ávila Reis, Jens F Rehfeld, Brid Callaghan, John B Furnes. Analysis of enteroendocrine cell populations in the human colon. Cell and tissue research. vol 367. issue 2. 2017-05-31. PMID:27844204. |
only four hormones, 5-hydroxytryptamine (5-ht), glucagon-like peptide 1 (glp-1), peptide yy (pyy) and somatostatin, were common in enteroendocrine cells of the human colon. |
2017-05-31 |
2023-08-13 |
human |
| Patricia Martins, Josiane Fakhry, Enio Chaves de Oliveira, Billie Hunne, Linda J Fothergill, Mitchell Ringuet, Débora d'Ávila Reis, Jens F Rehfeld, Brid Callaghan, John B Furnes. Analysis of enteroendocrine cell populations in the human colon. Cell and tissue research. vol 367. issue 2. 2017-05-31. PMID:27844204. |
the most numerous cells were 5-ht cells, some of which also contained pyy or somatostatin and very rarely glp-1. |
2017-05-31 |
2023-08-13 |
human |
| Yohan Reynaud, Josiane Fakhry, Linda Fothergill, Brid Callaghan, Mitchell Ringuet, Billie Hunne, David M Bravo, John B Furnes. The chemical coding of 5-hydroxytryptamine containing enteroendocrine cells in the mouse gastrointestinal tract. Cell and tissue research. vol 364. issue 3. 2017-03-06. PMID:26803512. |
small proportions of 5-ht cells contained gastrin or somatostatin in the stomach, pyy or glp-1 in the small intestine and glp-1 or somatostatin in the large intestine. |
2017-03-06 |
2023-08-13 |
mouse |
| Rozita H Anderberg, Jennifer E Richard, Caroline Hansson, Hans Nissbrandt, Filip Bergquist, Karolina P Skibick. GLP-1 is both anxiogenic and antidepressant; divergent effects of acute and chronic GLP-1 on emotionality. Psychoneuroendocrinology. vol 65. 2016-12-13. PMID:26724568. |
acute central glp-1 receptor stimulation also altered serotonin signaling in the amygdala. |
2016-12-13 |
2023-08-13 |
rat |
| Rozita H Anderberg, Jennifer E Richard, Caroline Hansson, Hans Nissbrandt, Filip Bergquist, Karolina P Skibick. GLP-1 is both anxiogenic and antidepressant; divergent effects of acute and chronic GLP-1 on emotionality. Psychoneuroendocrinology. vol 65. 2016-12-13. PMID:26724568. |
collectively we show a striking impact of central glp-1 on emotionality and the amygdala serotonin signaling that is divergent under acute versus chronic glp-1 activation conditions. |
2016-12-13 |
2023-08-13 |
rat |
| Katsunori Nonogaki, Takao Kaj. The acute anorexic effect of liraglutide, a GLP-1 receptor agonist, does not require functional leptin receptor, serotonin, and hypothalamic POMC and CART activities in mice. Diabetes research and clinical practice. vol 120. 2016-12-13. PMID:27585115. |
the acute anorexic effect of liraglutide, a glp-1 receptor agonist, does not require functional leptin receptor, serotonin, and hypothalamic pomc and cart activities in mice. |
2016-12-13 |
2023-08-13 |
mouse |