| Publication |
Sentence |
Publish Date |
Extraction Date |
Species |
| Alvin Ibarra, Kaisa Olli, Wilrike Pasman, Henk Hendriks, Esa Alhoniemi, Ghulam Shere Raza, Karl-Heinz Herzig, Kirsti Tiihone. Effects of polydextrose with breakfast or with a midmorning preload on food intake and other appetite-related parameters in healthy normal-weight and overweight females: An acute, randomized, double-blind, placebo-controlled, and crossover study. Appetite. vol 110. 2018-01-02. PMID:27916475. |
gastric emptying rates and the blood concentrations of glucose, insulin, cholecystokinin, ghrelin, glucagon-like peptide 1 (glp-1), and peptide tyrosine-tyrosine were measured in the group that received pdx as part of their breakfast. |
2018-01-02 |
2023-08-13 |
human |
| Alvin Ibarra, Kaisa Olli, Wilrike Pasman, Henk Hendriks, Esa Alhoniemi, Ghulam Shere Raza, Karl-Heinz Herzig, Kirsti Tiihone. Effects of polydextrose with breakfast or with a midmorning preload on food intake and other appetite-related parameters in healthy normal-weight and overweight females: An acute, randomized, double-blind, placebo-controlled, and crossover study. Appetite. vol 110. 2018-01-02. PMID:27916475. |
pdx intake with breakfast tended to elevate blood glucose (p = 0.06) during the postabsorptive phase, significantly lowered insulin by 15.7% (p = 0.04), and increased glp-1 by 39.9% (p = 0.02); no other effects on blood parameters or gastric emptying rates were observed. |
2018-01-02 |
2023-08-13 |
human |
| Alexander A Moghadam, Timothy H Moran, Megan J Daile. Alterations in circadian and meal-induced gut peptide levels in lean and obese rats. Experimental biology and medicine (Maywood, N.J.). vol 242. issue 18. 2018-01-02. PMID:29191090. |
the aim of this study was to identify the degree to which high-fat diet-induced obesity would alter the daily rhythm of gut peptide plasma levels (glucagon-like peptide-1 [glp-1], peptide yy [pyy], insulin or amylin [amy]) or meal-induced levels in the middle of the light or dark cycle. |
2018-01-02 |
2023-08-13 |
rat |
| Hong-Yan Cai, Jun-Ting Yang, Zhao-Jun Wang, Jun Zhang, Wei Yang, Mei-Na Wu, Jin-Shun Q. Lixisenatide reduces amyloid plaques, neurofibrillary tangles and neuroinflammation in an APP/PS1/tau mouse model of Alzheimer's disease. Biochemical and biophysical research communications. vol 495. issue 1. 2017-12-29. PMID:29175324. |
glucagon-like peptide-1 (glp-1) is an incretin hormone, normalises insulin signaling and acts as a neuroprotective growth factor. |
2017-12-29 |
2023-08-13 |
mouse |
| Linda Sundström, Susanna Myhre, Monika Sundqvist, Andrea Ahnmark, William McCoull, Piotr Raubo, Sam D Groombridge, Magnus Polla, Ann-Christin Nyström, Lisbeth Kristensson, Mats Någård, Maria Sörhede Winzel. The acute glucose lowering effect of specific GPR120 activation in mice is mainly driven by glucagon-like peptide 1. PloS one. vol 12. issue 12. 2017-12-29. PMID:29206860. |
exendin 9-39, a glp-1 receptor antagonist, abolished the gpr120 induced effects on glucose and insulin following an intravenous glucose challenge. |
2017-12-29 |
2023-08-13 |
mouse |
| Elena Previti, Serenella Salinari, Alessandro Bertuzzi, Esmeralda Capristo, Stephan Bornstein, Geltrude Mingron. Glycemic control after metabolic surgery: a Granger causality and graph analysis. American journal of physiology. Endocrinology and metabolism. vol 313. issue 5. 2017-12-27. PMID:28698280. |
twenty-four-hour plasma glucose, nefa, insulin, c-peptide, glucagon-like peptide-1 (glp-1), and gastric inhibitory polypeptide (gip) time courses were obtained and analyzed by granger causality and graph analyses. |
2017-12-27 |
2023-08-13 |
human |
| Elena Previti, Serenella Salinari, Alessandro Bertuzzi, Esmeralda Capristo, Stephan Bornstein, Geltrude Mingron. Glycemic control after metabolic surgery: a Granger causality and graph analysis. American journal of physiology. Endocrinology and metabolism. vol 313. issue 5. 2017-12-27. PMID:28698280. |
finally, not only did glp-1 levels play a central role, but also insulin and c-peptide levels had a comparable relevance in the network of healthy controls. |
2017-12-27 |
2023-08-13 |
human |
| Yoon Young Choi, Sung Hoon Noh, Ji Yeong A. A randomized controlled trial of Roux-en-Y gastrojejunostomy vs. gastroduodenostomy with respect to the improvement of type 2 diabetes mellitus after distal gastrectomy in gastric cancer patients. PloS one. vol 12. issue 12. 2017-12-26. PMID:29216250. |
diabetes medication status, biochemical and hormonal data including blood glucose, hba1c, insulin, c-peptide, homa-ir, ghrelin, leptin, glp-1, pyy, and gip were evaluated for 12 months after surgery. |
2017-12-26 |
2023-08-13 |
Not clear |
| Rilu Feng, Cheng Qian, Qianjing Liu, Yunqiu Jin, Lianyong Liu, Shengxian Li, Yu Liao, Huan Zhou, Wei Liu, Chris K Rayner, Jing M. Expression of sweet taste receptor and gut hormone secretion in modelled type 2 diabetes. General and comparative endocrinology. vol 252. 2017-12-22. PMID:28782537. |
blood samples were taken for measurement of blood glucose, plasma insulin, and glp-1 concentrations. |
2017-12-22 |
2023-08-13 |
rat |
| Neha Shrestha, Francisca Araújo, Mohammad-Ali Shahbazi, Ermei Mäkilä, Maria João Gomes, Mikko Airavaara, Esko I Kauppinen, Janne Raula, Jarno Salonen, Jouni Hirvonen, Bruno Sarmento, Hélder A Santo. Oral hypoglycaemic effect of GLP-1 and DPP4 inhibitor based nanocomposites in a diabetic animal model. Journal of controlled release : official journal of the Controlled Release Society. vol 232. 2017-12-20. PMID:27091697. |
glucagon-like peptide-1 (glp-1), an incretin hormone, is used for type 2 diabetes mellitus (t2dm) treatment because of its ability to stimulate insulin secretion and release in a glucose-dependent manner. |
2017-12-20 |
2023-08-13 |
rat |
| E Fernández-Millán, M A Martín, L Goya, E Lizárraga-Mollinedo, F Escrivá, S Ramos, C Álvare. Glucagon-like peptide-1 improves beta-cell antioxidant capacity via extracellular regulated kinases pathway and Nrf2 translocation. Free radical biology & medicine. vol 95. 2017-12-19. PMID:26968794. |
glucose-stimulated insulin secretion was also preserved in beta-cells challenged with tert-booh but pre-treated with glp-1, probably through the down-regulation of the mitochondrial uncoupling-protein2 (ucp2). |
2017-12-19 |
2023-08-13 |
Not clear |
| Rachael S Rigda, Laurence G Trahair, Tanya J Little, Tongzhi Wu, Scott Standfield, Christine Feinle-Bisset, Christopher K Rayner, Michael Horowitz, Karen L Jone. Regional specificity of the gut-incretin response to small intestinal glucose infusion in healthy older subjects. Peptides. vol 86. 2017-12-19. PMID:27780735. |
blood glucose, serum insulin and plasma glp-1, gip and cck responses were assessed. |
2017-12-19 |
2023-08-13 |
human |
| Rachael S Rigda, Laurence G Trahair, Tanya J Little, Tongzhi Wu, Scott Standfield, Christine Feinle-Bisset, Christopher K Rayner, Michael Horowitz, Karen L Jone. Regional specificity of the gut-incretin response to small intestinal glucose infusion in healthy older subjects. Peptides. vol 86. 2017-12-19. PMID:27780735. |
gp was associated with minimal glp-1 response (p=0.05), but substantial increases in gip, cck and insulin (p<0.001 for all). |
2017-12-19 |
2023-08-13 |
human |
| Rachael S Rigda, Laurence G Trahair, Tanya J Little, Tongzhi Wu, Scott Standfield, Christine Feinle-Bisset, Christopher K Rayner, Michael Horowitz, Karen L Jone. Regional specificity of the gut-incretin response to small intestinal glucose infusion in healthy older subjects. Peptides. vol 86. 2017-12-19. PMID:27780735. |
gpd and gd both stimulated glp-1, gip, cck and insulin (p<0.001 for all). |
2017-12-19 |
2023-08-13 |
human |
| Takeshi Osonoi, Miyoko Saito, Natsuyo Hariya, Moritaka Goto, Kazuki Mochizuk. Add-on therapy with anagliptin in Japanese patients with type-2 diabetes mellitus treated with metformin and miglitol can maintain higher concentrations of biologically active GLP-1/total GIP and a lower concentration of leptin. Peptides. vol 86. 2017-12-19. PMID:27780736. |
metformin, α-glucosidase inhibitors (α-gis), and dipeptidyl peptidase 4 inhibitors (dpp-4is) reduce hyperglycemia without excessive insulin secretion, and enhance postprandial plasma concentration of glucagon-like peptide-1 (glp-1) in type-2 diabetes mellitus (t2dm) patients. |
2017-12-19 |
2023-08-13 |
Not clear |
| M Saqui-Salces, Z Luo, P E Urriola, B J Kerr, G C Shurso. Effect of dietary fiber and diet particle size on nutrient digestibility and gastrointestinal secretory function in growing pigs. Journal of animal science. vol 95. issue 6. 2017-12-19. PMID:28727063. |
pigs were fed finely (374 ± 29 µm) or coarsely (631 ± 35 µm) ground corn-soybean meal (csb), csb + 35% corn dried distillers' grains with solubles (ddgs), and csb with 21% soybean hulls (sbh) diets for 49 d. diet composition, nutrient digestibility, along with fasting plasma concentrations of gastrin, insulin, glucagon-like peptide-1 (glp-1), glucose-dependent insulinotropic peptide (gip), tba, cholesterol, and glucose were measured. |
2017-12-19 |
2023-08-13 |
Not clear |
| M Saqui-Salces, Z Luo, P E Urriola, B J Kerr, G C Shurso. Effect of dietary fiber and diet particle size on nutrient digestibility and gastrointestinal secretory function in growing pigs. Journal of animal science. vol 95. issue 6. 2017-12-19. PMID:28727063. |
the dc and ps affected plasma gastrin, insulin and tba but not gip, glp-1, glucose, and cholesterol. |
2017-12-19 |
2023-08-13 |
Not clear |
| Eva Tudurí, Miguel López, Carlos Diéguez, Angel Nadal, Rubén Nogueira. Glucagon-Like Peptide 1 Analogs and their Effects on Pancreatic Islets. Trends in endocrinology and metabolism: TEM. vol 27. issue 5. 2017-12-18. PMID:27062006. |
glp-1 stimulates glucose-stimulated insulin secretion and protects β cells, while its extrapancreatic effects include cardioprotection, reduction of hepatic glucose production, and regulation of satiety. |
2017-12-18 |
2023-08-13 |
Not clear |
| Eva Tudurí, Miguel López, Carlos Diéguez, Angel Nadal, Rubén Nogueira. Glucagon-Like Peptide 1 Analogs and their Effects on Pancreatic Islets. Trends in endocrinology and metabolism: TEM. vol 27. issue 5. 2017-12-18. PMID:27062006. |
based on the results from in vitro and in vivo studies in humans and animal models, we describe the specific actions of glp-1 analogs on the synthesis, processing, and secretion of insulin, islet morphology, and β cell proliferation and apoptosis. |
2017-12-18 |
2023-08-13 |
Not clear |
| Giulia Cantini, Edoardo Mannucci, Michaela Lucon. Perspectives in GLP-1 Research: New Targets, New Receptors. Trends in endocrinology and metabolism: TEM. vol 27. issue 6. 2017-12-18. PMID:27091492. |
the incretin hormone glucagon-like peptide-1 (glp-1) binds to and activates its g-protein-coupled-receptor glp-1r to reduce glycaemia through the stimulation of insulin and suppression of pancreatic glucagon secretion. |
2017-12-18 |
2023-08-13 |
Not clear |