| Publication |
Sentence |
Publish Date |
Extraction Date |
Species |
| Elizabeth Adams, Pauline Genter, Emma Keefe, Kevin Sandow, Virginia Gray, Jerome I Rotter, Yii-Der Ida Chen, Eli Ip. The GLP-1 response to glucose does not mediate beta and alpha cell dysfunction in Hispanics with abnormal glucose metabolism. Diabetes research and clinical practice. vol 135. 2018-05-04. PMID:29155153. |
glucagon-like peptide-1 (glp-1) contributes to insulin secretion after meals. |
2018-05-04 |
2023-08-13 |
Not clear |
| Nikki Cassie, Richard L Anderson, Dana Wilson, Anne Pawsey, Julian G Mercer, Perry Barret. Body weight loss, effective satiation and absence of homeostatic neuropeptide compensation in male Sprague Dawley rats schedule fed a protein crosslinked diet. Appetite. vol 117. 2018-05-03. PMID:28687371. |
compared to rats fed a solid diet, acute responses in circulating glp-1, leptin and insulin were eliminated or attenuated in rats fed a liquid or crosslinked diet. |
2018-05-03 |
2023-08-13 |
human |
| Anders Albèr, Andreas Brønden, Filip K Kno. Short-acting glucagon-like peptide-1 receptor agonists as add-on to insulin therapy in type 1 diabetes: A review. Diabetes, obesity & metabolism. vol 19. issue 7. 2018-05-02. PMID:28211611. |
glucagon-like peptide-1 (glp-1) receptor agonists (ras) are the focus of increasing interest as a possible adjunctive treatment to insulin in type 1 diabetes because of their glucagonostatic and extrapancreatic effects. |
2018-05-02 |
2023-08-13 |
Not clear |
| Daniel Sterzi, Sébastien Auziere, Marie Markert Jensen, Sandra Lope. Diabetes injectable therapy: type 2 diabetes management in Danish practice. Current medical research and opinion. vol 33. issue 12. 2018-05-01. PMID:28875722. |
gps felt more comfortable with initiating the first injectable therapy (defined as a glucagon-like peptide-1 receptor agonist (glp-1 ra) or basal insulin) than the second (defined as adding a basal insulin in patients treated with a glp-1 ra (± oral anti-diabetic treatments [oads]), or adding either a glp-1 ra or a bolus insulin in patients treated with basal insulin (± oads). |
2018-05-01 |
2023-08-13 |
Not clear |
| Dan Kawamori, Jun Shirakawa, Chong Wee Liew, Jiang Hu, Tomoaki Morioka, Alokesh Duttaroy, Bryan Burkey, Rohit N Kulkarn. GLP-1 signalling compensates for impaired insulin signalling in regulating beta cell proliferation in βIRKO mice. Diabetologia. vol 60. issue 8. 2018-04-30. PMID:28526921. |
glp-1 signalling compensates for impaired insulin signalling in regulating beta cell proliferation in βirko mice. |
2018-04-30 |
2023-08-13 |
mouse |
| Dan Kawamori, Jun Shirakawa, Chong Wee Liew, Jiang Hu, Tomoaki Morioka, Alokesh Duttaroy, Bryan Burkey, Rohit N Kulkarn. GLP-1 signalling compensates for impaired insulin signalling in regulating beta cell proliferation in βIRKO mice. Diabetologia. vol 60. issue 8. 2018-04-30. PMID:28526921. |
we aimed to investigate potential interactions between insulin and glucagon-like peptide (glp)-1 signalling pathways in the regulation of beta cell-cycle dynamics in vivo, in the context of the therapeutic potential of glp-1 to modulate impaired beta cell function. |
2018-04-30 |
2023-08-13 |
mouse |
| Renata A Bagarolli, Natália Tobar, Alexandre G Oliveira, Tiago G Araújo, Bruno M Carvalho, Guilherme Z Rocha, Juliana F Vecina, Kelly Calisto, Dioze Guadagnini, Patrícia O Prada, Andrey Santos, Sara T O Saad, Mario J A Saa. Probiotics modulate gut microbiota and improve insulin sensitivity in DIO mice. The Journal of nutritional biochemistry. vol 50. 2018-04-30. PMID:28968517. |
blood was drawn to determine levels of glucose, insulin, lps, cytokines and glp-1. |
2018-04-30 |
2023-08-13 |
mouse |
| Fang-Hong Shi, Hao Li, Min Cui, Zai-Li Zhang, Zhi-Chun Gu, Xiao-Yan Li. Efficacy and safety of once-weekly semaglutide for the treatment of type 2 diabetes: Protocol for a systematic review and meta-analysis. Medicine. vol 97. issue 16. 2018-04-24. PMID:29668601. |
glucagon-like peptide-1 (glp-1) receptor agonists (glp-1 ras) can stimulate glucose-dependent insulin while inhibit glucagon secretion, delay gastric emptying, reduce appetite, and energy intake. |
2018-04-24 |
2023-08-13 |
Not clear |
| Hari B Keshava, Ashkan Mowla, Leslie J Heinberg, Philip R Schauer, Stacy A Brethauer, Ali Aminia. Bariatric surgery may reduce the risk of Alzheimer's diseases through GLP-1 mediated neuroprotective effects. Medical hypotheses. vol 104. 2018-04-23. PMID:28673587. |
glp-1 improves insulin secretion, inhibits apoptosis and induce pancreatic islet neogenesis, promotes satiety, and can regulate heart rate and blood pressure. |
2018-04-23 |
2023-08-13 |
Not clear |
| Jiping Yue, Xuewen Gou, Yuanyuan Li, Barton Wicksteed, Xiaoyang W. Engineered Epidermal Progenitor Cells Can Correct Diet-Induced Obesity and Diabetes. Cell stem cell. vol 21. issue 2. 2018-04-23. PMID:28777946. |
glp-1 induction from engineered mouse cells grafted onto immunocompetent hosts increased insulin secretion and reversed high-fat-diet-induced weight gain and insulin resistance. |
2018-04-23 |
2023-08-13 |
mouse |
| Jenq-Lin Yang, Wei-Yu Chen, Shang-Der Che. The Emerging Role of GLP-1 Receptors in DNA Repair: Implications in Neurological Disorders. International journal of molecular sciences. vol 18. issue 9. 2018-04-23. PMID:28846606. |
glucagon-like peptide-1 (glp-1) is originally found as a metabolic hormone (incretin) that is able to regulate blood-glucose levels via promoting synthesis and secretion of insulin. |
2018-04-23 |
2023-08-13 |
rat |
| Christian Anholm, Preman Kumarathurai, Lene R Pedersen, Olav W Nielsen, Ole P Kristiansen, Mogens Fenger, Sten Madsbad, Ahmad Sajadieh, Steen B Haugaar. Liraglutide effects on beta-cell, insulin sensitivity and glucose effectiveness in patients with stable coronary artery disease and newly diagnosed type 2 diabetes. Diabetes, obesity & metabolism. vol 19. issue 6. 2018-04-03. PMID:28124822. |
the aims of the study were to investigate the effects of the glp-1 receptor agonist liraglutide as add-on to metformin on insulin sensitivity (si) and glucose effectiveness (sg) in addition to its positive effects on beta-cell function in overweight/obese patients with coronary artery disease (cad) and type 2 diabetes mellitus (t2dm). |
2018-04-03 |
2023-08-13 |
Not clear |
| Genevieve E Fava, Emily W Dong, Hongju W. Intra-islet glucagon-like peptide 1. Journal of diabetes and its complications. vol 30. issue 8. 2018-03-28. PMID:27267264. |
glucagon-like peptide-1 (glp-1) is originally identified in the gut as an incretin hormone, and it is potent in stimulating insulin secretion in the pancreas. |
2018-03-28 |
2023-08-13 |
Not clear |
| M Sani, E Ayub. Comments on "Insulin resistance, postprandial GLP-1 and adaptive immunity are the main predictors of NAFLD in a homogeneous population at high cardiovascular risk". Nutrition, metabolism, and cardiovascular diseases : NMCD. vol 27. issue 1. 2018-03-27. PMID:28061944. |
comments on "insulin resistance, postprandial glp-1 and adaptive immunity are the main predictors of nafld in a homogeneous population at high cardiovascular risk". |
2018-03-27 |
2023-08-13 |
Not clear |
| Sergei Pechenov, Himanshu Bhattacharjee, Daniel Yin, Sachin Mittal, J Anand Subramon. Improving drug-like properties of insulin and GLP-1 via molecule design and formulation and improving diabetes management with device & drug delivery. Advanced drug delivery reviews. vol 112. 2018-03-20. PMID:28153578. |
improving drug-like properties of insulin and glp-1 via molecule design and formulation and improving diabetes management with device & drug delivery. |
2018-03-20 |
2023-08-13 |
Not clear |
| Sergei Pechenov, Himanshu Bhattacharjee, Daniel Yin, Sachin Mittal, J Anand Subramon. Improving drug-like properties of insulin and GLP-1 via molecule design and formulation and improving diabetes management with device & drug delivery. Advanced drug delivery reviews. vol 112. 2018-03-20. PMID:28153578. |
the discovery of insulin revolutionized the management of diabetes, the revelation of glucagon-like peptide-1 (glp-1) and introduction of glp-1 receptor agonists to clinical practice was another breakthrough. |
2018-03-20 |
2023-08-13 |
Not clear |
| Sergei Pechenov, Himanshu Bhattacharjee, Daniel Yin, Sachin Mittal, J Anand Subramon. Improving drug-like properties of insulin and GLP-1 via molecule design and formulation and improving diabetes management with device & drug delivery. Advanced drug delivery reviews. vol 112. 2018-03-20. PMID:28153578. |
advances in self-administration of insulin and glp-1 receptor agonist therapies with use of drug-device combination products have further improved the outcomes of diabetes management and quality of life for diabetic patients. |
2018-03-20 |
2023-08-13 |
Not clear |
| Sergei Pechenov, Himanshu Bhattacharjee, Daniel Yin, Sachin Mittal, J Anand Subramon. Improving drug-like properties of insulin and GLP-1 via molecule design and formulation and improving diabetes management with device & drug delivery. Advanced drug delivery reviews. vol 112. 2018-03-20. PMID:28153578. |
the synergies of insulin and glp-1 receptor agonist actions have led to development of devices that can deliver both molecules simultaneously. |
2018-03-20 |
2023-08-13 |
Not clear |
| Sergei Pechenov, Himanshu Bhattacharjee, Daniel Yin, Sachin Mittal, J Anand Subramon. Improving drug-like properties of insulin and GLP-1 via molecule design and formulation and improving diabetes management with device & drug delivery. Advanced drug delivery reviews. vol 112. 2018-03-20. PMID:28153578. |
the objective of this review is to summarize molecular designs to improve the drug-like properties of insulin and glp-1 and to highlight the continued advancement of drug-device combination products to improve diabetes management. |
2018-03-20 |
2023-08-13 |
Not clear |
| M Elsabagh, Y Inabu, T Obitsu, T Sugin. Response of plasma glucagon-like peptide-2 to feeding pattern and intraruminal administration of volatile fatty acids in sheep. Domestic animal endocrinology. vol 60. 2018-03-20. PMID:28431319. |
in both experiments, plasma glp-2, glucagon-like peptide-1 (glp-1), glucose, insulin, and β-hydroxy butyric acid (bhba) levels were measured. |
2018-03-20 |
2023-08-13 |
Not clear |