| Publication |
Sentence |
Publish Date |
Extraction Date |
Species |
| Tassia Gomide Braga, Maria das Graças Coelho de Souza, Priscila Alves Maranhão, Michel Menezes, Ludmilla Dellatorre-Teixeira, Eliete Bouskela, Carel W Le Roux, Luiz Guilherme Kraemer-Aguia. Evaluation of Heart Rate Variability and Endothelial Function 3 Months After Bariatric Surgery. Obesity surgery. vol 30. issue 6. 2021-04-14. PMID:31916132. |
glucagon-like peptide 1 (glp-1), insulin, and glucose at fasting and 30 and 60 min after a standard 300-kcal meal were also analyzed. |
2021-04-14 |
2023-08-13 |
Not clear |
| Tassia Gomide Braga, Maria das Graças Coelho de Souza, Priscila Alves Maranhão, Michel Menezes, Ludmilla Dellatorre-Teixeira, Eliete Bouskela, Carel W Le Roux, Luiz Guilherme Kraemer-Aguia. Evaluation of Heart Rate Variability and Endothelial Function 3 Months After Bariatric Surgery. Obesity surgery. vol 30. issue 6. 2021-04-14. PMID:31916132. |
changes in glp-1 and insulin resistance markers did not correlate with hrv. |
2021-04-14 |
2023-08-13 |
Not clear |
| Jessica A Huthmacher, Juris J Meier, Michael A Nauc. Efficacy and Safety of Short- and Long-Acting Glucagon-Like Peptide 1 Receptor Agonists on a Background of Basal Insulin in Type 2 Diabetes: A Meta-analysis. Diabetes care. vol 43. issue 9. 2021-04-13. PMID:32910778. |
to compare the efficacy and safety of short- and long-acting glucagon-like peptide 1 receptor agonists (glp-1 ras), both used in combination with basal insulin, in patients with type 2 diabetes. |
2021-04-13 |
2023-08-13 |
Not clear |
| Alessandro Matarese, Jessica Gambardella, Angela Lombardi, Xujun Wang, Gaetano Santull. miR-7 Regulates GLP-1-Mediated Insulin Release by Targeting β-Arrestin 1. Cells. vol 9. issue 7. 2021-04-12. PMID:32640511. |
glucagon-like peptide-1 (glp-1) has been shown to potentiate glucose-stimulated insulin secretion binding glp-1 receptor on pancreatic β cells. |
2021-04-12 |
2023-08-13 |
Not clear |
| Alessandro Matarese, Jessica Gambardella, Angela Lombardi, Xujun Wang, Gaetano Santull. miR-7 Regulates GLP-1-Mediated Insulin Release by Targeting β-Arrestin 1. Cells. vol 9. issue 7. 2021-04-12. PMID:32640511. |
then, we verified that glp-1 was indeed able to regulate the transcription of mir-7 and βarr1, and that mir-7 significantly regulated glp-1-induced insulin release and cyclic amp (camp) production in β cells. |
2021-04-12 |
2023-08-13 |
Not clear |
| Takumi Nakamura, Kazuki Harada, Taichi Kamiya, Mai Takizawa, Jim Küppers, Kazuo Nakajima, Michael Gütschow, Tetsuya Kitaguchi, Kunihiro Ohta, Tadafumi Kato, Takashi Tsubo. Glutamine-induced signaling pathways via amino acid receptors in enteroendocrine L cell lines. Journal of molecular endocrinology. vol 64. issue 3. 2021-04-08. PMID:31940281. |
glucagon-like peptide-1 (glp-1), secreted by gastrointestinal enteroendocrine l cells, induces insulin secretion and is important for glucose homeostasis. |
2021-04-08 |
2023-08-13 |
Not clear |
| Huanliang Liu, Lijie Tian, Dayong Wan. Notch receptor GLP-1 regulates toxicity of simulated microgravity stress by activating germline-intestine communication of insulin signaling in C. elegans. Biochemical and biophysical research communications. vol 534. 2021-04-08. PMID:33280816. |
notch receptor glp-1 regulates toxicity of simulated microgravity stress by activating germline-intestine communication of insulin signaling in c. elegans. |
2021-04-08 |
2023-08-13 |
caenorhabditis_elegans |
| Huanliang Liu, Lijie Tian, Dayong Wan. Notch receptor GLP-1 regulates toxicity of simulated microgravity stress by activating germline-intestine communication of insulin signaling in C. elegans. Biochemical and biophysical research communications. vol 534. 2021-04-08. PMID:33280816. |
in simulated microgravity treated worms, germline rnai knockdown of glp-1 decreased expressions of daf-28, ins-39, and ins-8 encoding insulin peptides, and resistance to simulated microgravity toxicity could be detected in daf-28(rnai), ins-39(rnai), and ins-8(rnai) worms. |
2021-04-08 |
2023-08-13 |
caenorhabditis_elegans |
| Maria Mirabelli, Eusebio Chiefari, Vera Tocci, Patrizia Caroleo, Stefania Giuliano, Emanuela Greco, Raul Miguel Luque, Luigi Puccio, Daniela Patrizia Foti, Antonio Aversa, Antonio Brunett. Clinical Effectiveness and Safety of Once-Weekly GLP-1 Receptor Agonist Dulaglutide as Add-On to Metformin or Metformin Plus Insulin Secretagogues in Obesity and Type 2 Diabetes. Journal of clinical medicine. vol 10. issue 5. 2021-04-08. PMID:33801192. |
clinical effectiveness and safety of once-weekly glp-1 receptor agonist dulaglutide as add-on to metformin or metformin plus insulin secretagogues in obesity and type 2 diabetes. |
2021-04-08 |
2023-08-13 |
Not clear |
| Maria Mirabelli, Eusebio Chiefari, Vera Tocci, Patrizia Caroleo, Stefania Giuliano, Emanuela Greco, Raul Miguel Luque, Luigi Puccio, Daniela Patrizia Foti, Antonio Aversa, Antonio Brunett. Clinical Effectiveness and Safety of Once-Weekly GLP-1 Receptor Agonist Dulaglutide as Add-On to Metformin or Metformin Plus Insulin Secretagogues in Obesity and Type 2 Diabetes. Journal of clinical medicine. vol 10. issue 5. 2021-04-08. PMID:33801192. |
the aim of this monocentric retrospective observational study was to evaluate the 18-month safety and effectiveness of glp-1 receptor agonist (glp-1 ra) dulaglutide (du) 1.5 mg/once weekly as an add-on to metformin (met) or met plus conventional insulin secretagogues in a study cohort with excess body weight and type 2 diabetes (t2d). |
2021-04-08 |
2023-08-13 |
Not clear |
| Ian Rollo, Javier T Gonzalez, Cas J Fuchs, Luc J C van Loon, Clyde William. Primary, Secondary, and Tertiary Effects of Carbohydrate Ingestion During Exercise. Sports medicine (Auckland, N.Z.). vol 50. issue 11. 2021-04-05. PMID:32936440. |
the intestinal mucosa has carbohydrate sensors that stimulate the release of two 'incretin' hormones (gip and glp-1) whose actions range from the secretion of insulin to appetite regulation. |
2021-04-05 |
2023-08-13 |
Not clear |
| Matthew P Gilbert, Richard E Pratle. GLP-1 Analogs and DPP-4 Inhibitors in Type 2 Diabetes Therapy: Review of Head-to-Head Clinical Trials. Frontiers in endocrinology. vol 11. 2021-03-29. PMID:32308645. |
in patients with type 2 diabetes (t2dm), an impaired insulin response to glp-1 and gip contributes to hyperglycemia. |
2021-03-29 |
2023-08-13 |
human |
| Sodai Kubota, Yanyan Liu, Katsumi Iizuka, Hitoshi Kuwata, Yutaka Seino, Daisuke Yab. A Review of Recent Findings on Meal Sequence: An Attractive Dietary Approach to Prevention and Management of Type 2 Diabetes. Nutrients. vol 12. issue 9. 2021-03-29. PMID:32825124. |
meal sequence, i.e., consumption of protein and/or fat before carbohydrate, promotes secretion of glucagon-like peptide-1 (glp-1) from the gut and ameliorates secretions of insulin and glucagon and delays gastric emptying, thereby improving postprandial glucose excursion. |
2021-03-29 |
2023-08-13 |
Not clear |
| Thinzar Min, Stephen C Bai. The Role of Tirzepatide, Dual GIP and GLP-1 Receptor Agonist, in the Management of Type 2 Diabetes: The SURPASS Clinical Trials. Diabetes therapy : research, treatment and education of diabetes and related disorders. vol 12. issue 1. 2021-03-23. PMID:33325008. |
however, emerging evidence has illustrated that co-infusion of glp-1 and gip has a synergetic effect, resulting in significantly increased insulin response and glucagonostatic response, compared with separate administration of each hormone. |
2021-03-23 |
2023-08-13 |
Not clear |
| Tianmin Yuan, Zhujun Yin, Zhixiang Yan, Qing Hao, Jin Zeng, Li Li, Junning Zha. Tetrahydrocurcumin ameliorates diabetes profiles of db/db mice by altering the composition of gut microbiota and up-regulating the expression of GLP-1 in the pancreas. Fitoterapia. vol 146. 2021-03-22. PMID:32531320. |
serum insulin levels, the expression of glp-1 in the pancreas, the histopathology of pancreas and the composition of gut microbiota were evaluated at the end of the experiment. |
2021-03-22 |
2023-08-13 |
mouse |
| Tianmin Yuan, Zhujun Yin, Zhixiang Yan, Qing Hao, Jin Zeng, Li Li, Junning Zha. Tetrahydrocurcumin ameliorates diabetes profiles of db/db mice by altering the composition of gut microbiota and up-regulating the expression of GLP-1 in the pancreas. Fitoterapia. vol 146. 2021-03-22. PMID:32531320. |
compared to the diabetic group, thc treatment decreased significantly blood glucose, increased the secretion of insulin and the expression of glp-1 in the pancreas. |
2021-03-22 |
2023-08-13 |
mouse |
| Tuğba Bal, Yasemin Inceoglu, Erdal Karaoz, Seda Kizile. Sensitivity Study for the Key Parameters in Heterospheroid Preparation with Insulin-Secreting β-Cells and Mesenchymal Stem Cells. ACS biomaterials science & engineering. vol 5. issue 10. 2021-03-22. PMID:33455228. |
insulin secretion was further promoted with glucagon like peptide-1 (glp-1) incorporation within peg hydrogel structure. |
2021-03-22 |
2023-08-13 |
Not clear |
| Tuğba Bal, Yasemin Inceoglu, Erdal Karaoz, Seda Kizile. Sensitivity Study for the Key Parameters in Heterospheroid Preparation with Insulin-Secreting β-Cells and Mesenchymal Stem Cells. ACS biomaterials science & engineering. vol 5. issue 10. 2021-03-22. PMID:33455228. |
overall, this study comprehensively presents the optimum conditions for the preparation of min6-msc spheroids, utilizes mscs and glp-1 functional peg hydrogels as a scaffold to retain insulin secretion function and further demonstrates protection of heterospheroids exposed to proinflammatory cytokines. |
2021-03-22 |
2023-08-13 |
Not clear |
| Geremia B Bolli, Francesca Porcellati, Juris J Meie. Switching From Insulin Bolus Treatment to GLP-1 RAs Added to Continued Basal Insulin in People With Type 2 Diabetes on Basal-Bolus Insulin. Diabetes care. vol 43. issue 10. 2021-03-15. PMID:32958617. |
switching from insulin bolus treatment to glp-1 ras added to continued basal insulin in people with type 2 diabetes on basal-bolus insulin. |
2021-03-15 |
2023-08-13 |
Not clear |
| Fiona M Gribble, Frank Reiman. Metabolic Messengers: glucagon-like peptide 1. Nature metabolism. vol 3. issue 2. 2021-03-15. PMID:33432200. |
glucagon like peptide-1 (glp-1), a peptide hormone from the intestinal tract, plays a central role in the coordination of postprandial glucose homeostasis through actions on insulin secretion, food intake and gut motility. |
2021-03-15 |
2023-08-13 |
human |