| Publication |
Sentence |
Publish Date |
Extraction Date |
Species |
| Imre Farkas, Csaba Vastagh, Erzsébet Farkas, Flóra Bálint, Katalin Skrapits, Erik Hrabovszky, Csaba Fekete, Zsolt Liposit. Glucagon-Like Peptide-1 Excites Firing and Increases GABAergic Miniature Postsynaptic Currents (mPSCs) in Gonadotropin-Releasing Hormone (GnRH) Neurons of the Male Mice via Activation of Nitric Oxide (NO) and Suppression of Endocannabinoid Signaling Pathways. Frontiers in cellular neuroscience. vol 10. 2016-09-27. PMID:27672360. |
furthermore, glp-1 immunoreactive (ir) axons innervated gnrh neurons in the hypothalamus suggesting that glp-1 of both peripheral and neuronal sources can modulate gnrh neurons. |
2016-09-27 |
2023-08-13 |
mouse |
| Jazyra Zynat, Yuyu Guo, Yingli Lu, Dongping Li. The Improvement of Hyperglycemia after RYGB Surgery in Diabetic Rats Is Related to Elevated Hypothalamus GLP-1 Receptor Expression. International journal of endocrinology. vol 2016. 2016-09-20. PMID:27648071. |
the improvement of hyperglycemia after rygb surgery in diabetic rats is related to elevated hypothalamus glp-1 receptor expression. |
2016-09-20 |
2023-08-13 |
rat |
| Jazyra Zynat, Yuyu Guo, Yingli Lu, Dongping Li. The Improvement of Hyperglycemia after RYGB Surgery in Diabetic Rats Is Related to Elevated Hypothalamus GLP-1 Receptor Expression. International journal of endocrinology. vol 2016. 2016-09-20. PMID:27648071. |
this study aimed to explore the expression of glp-1 receptor in hypothalamus and gastrointestinal tissues after roux-en-y gastric bypass (rygb) surgery in diabetic rats. |
2016-09-20 |
2023-08-13 |
rat |
| Jazyra Zynat, Yuyu Guo, Yingli Lu, Dongping Li. The Improvement of Hyperglycemia after RYGB Surgery in Diabetic Rats Is Related to Elevated Hypothalamus GLP-1 Receptor Expression. International journal of endocrinology. vol 2016. 2016-09-20. PMID:27648071. |
rygb efficiently promoted serum glp-1 levels and the expression of glp-1 receptor in the hypothalamus in diabetic rats. |
2016-09-20 |
2023-08-13 |
rat |
| Jazyra Zynat, Yuyu Guo, Yingli Lu, Dongping Li. The Improvement of Hyperglycemia after RYGB Surgery in Diabetic Rats Is Related to Elevated Hypothalamus GLP-1 Receptor Expression. International journal of endocrinology. vol 2016. 2016-09-20. PMID:27648071. |
these data suggest that the hypothalamus glp-1r may play an important role in the glp-1 system for improving glucose homeostasis after reconstruction of the gastrointestinal tract. |
2016-09-20 |
2023-08-13 |
rat |
| Djordje S Popovic, Edita Stokic, Stevan L Popovi. GLP-1 Receptor Agonists and Type 1 Diabetes - Where Do We Stand? Current pharmaceutical design. vol 21. issue 36. 2016-08-15. PMID:26438316. |
glp-1 exerts its effects through the interaction with glp-1 receptor expressed in the pancreatic islets, lung, hypothalamus, stomach, heart and kidney. |
2016-08-15 |
2023-08-13 |
Not clear |
| N Gallo-Paye. Central (mainly) actions of GPCRs in energy homeostasis/balance: view from the Chair. International journal of obesity supplements. vol 4. issue Suppl 1. 2016-05-06. PMID:27152161. |
presentations were focused on melanocortin-3 receptor (mc3r) and melanin-concentrating hormone (mch) as anorexigenic and orexigenic components of the hypothalamus, on endocannabinoid receptors, initially as a central neuromodulatory signal, and on glucagon-like peptide-1 (glp-1) and gastric inhibitory polypeptide (gip) as peripheral signals. |
2016-05-06 |
2023-08-13 |
Not clear |
| Jennifer E Richard, Rozita H Anderberg, Andreas Göteson, Fiona M Gribble, Frank Reimann, Karolina P Skibick. Activation of the GLP-1 receptors in the nucleus of the solitary tract reduces food reward behavior and targets the mesolimbic system. PloS one. vol 10. issue 3. 2016-02-09. PMID:25793511. |
the gut/brain peptide, glucagon like peptide 1 (glp-1), suppresses food intake by acting on receptors located in key energy balance regulating cns areas, the hypothalamus or the hindbrain. |
2016-02-09 |
2023-08-13 |
rat |
| Verónica Outeiriño-Iglesias, Marina Romaní-Pérez, Lucas C González-Matías, Eva Vigo, Federico Mall. GLP-1 Increases Preovulatory LH Source and the Number of Mature Follicles, As Well As Synchronizing the Onset of Puberty in Female Rats. Endocrinology. vol 156. issue 11. 2016-02-02. PMID:26252058. |
in adult rats, glp-1 receptor expression varies during the estrous cycle at the hypothalamus, pituitary, and ovary. |
2016-02-02 |
2023-08-13 |
rat |
| Miguel López, Carlos Diéguez, Rubén Nogueira. Hypothalamic GLP-1: the control of BAT thermogenesis and browning of white fat. Adipocyte. vol 4. issue 2. 2015-07-13. PMID:26167417. |
our group has recently reported that stimulation of brain glp-1 receptors in the ventromedial nucleus of the hypothalamus is essential for the activation not only of bat thermogenesis, but also browning of white fat. |
2015-07-13 |
2023-08-13 |
Not clear |
| Baptist Gallwit. Extra-pancreatic effects of incretin-based therapies. Endocrine. vol 47. issue 2. 2015-06-24. PMID:24604239. |
glp-1 as well as a treatment with glp-1 ra also induces a stable body weight loss by affecting glp-1 signaling in the hypothalamus and by slowing gastric emptying. |
2015-06-24 |
2023-08-12 |
Not clear |
| Jörgen A Engel, Elisabet Jerlha. Role of appetite-regulating peptides in the pathophysiology of addiction: implications for pharmacotherapy. CNS drugs. vol 28. issue 10. 2015-06-04. PMID:24958205. |
this gut-brain hormone reduces food intake as well as regulates glucose homeostasis, foremost via glp-1 receptors in hypothalamus and brain stem. |
2015-06-04 |
2023-08-13 |
human |
| Meera Shah, Adrian Vell. Effects of GLP-1 on appetite and weight. Reviews in endocrine & metabolic disorders. vol 15. issue 3. 2015-03-30. PMID:24811133. |
glucagon-like peptide 1 (glp-1) is a cleavage product of the pre-proglucagon gene which is expressed in the α-cells of the pancreas, the l-cells of the intestine, and neurons located in the caudal brainstem and hypothalamus. |
2015-03-30 |
2023-08-13 |
Not clear |
| India A Reddy, Gregg D Stanwood, Aurelio Gall. Moving beyond energy homeostasis: new roles for glucagon-like peptide-1 in food and drug reward. Neurochemistry international. vol 73. 2015-02-02. PMID:24140429. |
historically this central role has largely been attributed to glp-1 receptor signaling in the brainstem and hypothalamus. |
2015-02-02 |
2023-08-12 |
Not clear |
| Sze Wa Chan, Zengbing Lu, Ge Lin, David Tai Wai Yew, Chi Kong Yeung, John A Rud. The differential antiemetic properties of GLP-1 receptor antagonist, exendin (9-39) in Suncus murinus (house musk shrew). Neuropharmacology. vol 83. 2015-01-29. PMID:24726308. |
previous studies using suncus murinus revealed that the glp-1 receptor agonist, exendin-4, induces emesis via the brainstem and/or hypothalamus. |
2015-01-29 |
2023-08-13 |
Not clear |
| Janine J Geerling, Mariëtte R Boon, Sander Kooijman, Edwin T Parlevliet, Louis M Havekes, Johannes A Romijn, Illiana M Meurs, Patrick C N Rense. Sympathetic nervous system control of triglyceride metabolism: novel concepts derived from recent studies. Journal of lipid research. vol 55. issue 2. 2014-09-28. PMID:24285857. |
various neuronal populations, such as neuropeptide y (npy)-expressing neurons and melanocortin-expressing neurons, as well as peripherally produced hormones (i.e., glp-1, leptin, and insulin), modulate sympathetic outflow from the hypothalamus toward target organs and thereby influence peripheral tg metabolism. |
2014-09-28 |
2023-08-12 |
Not clear |
| Noemi González-Abuín, Neus Martínez-Micaelo, Mayte Blay, Anna Ardévol, Montserrat Pinen. Grape-seed procyanidins prevent the cafeteria-diet-induced decrease of glucagon-like peptide-1 production. Journal of agricultural and food chemistry. vol 62. issue 5. 2014-07-18. PMID:24410268. |
in the same context, gspe avoided the decrease on intestinal dipeptidyl-peptidase 4 (dpp4) activity and modulated the gene expression of glp-1 and its receptor in the hypothalamus. |
2014-07-18 |
2023-08-12 |
rat |
| Rémy Burceli. [New insights into adipose cell biology]. Bulletin de l'Academie nationale de medecine. vol 197. issue 1. 2014-04-23. PMID:24672981. |
we then found that the enteric-vagal nervous system transmits this nutritional information towards the brain stem and hypothalamus, where leptin, neuropeptide y and glp-1 relay the enteric signal to control the endocrine pancreas (insulin-glucagon secretion), the liver (glycogen metabolism), the vascular system (vasodilation, arterial flow), and muscle metabolism. |
2014-04-23 |
2023-08-12 |
mouse |
| Mona A Abraham, Jessica T Y Yue, Mary P LaPierre, Guy A Rutter, Peter E Light, Beatrice M Filippi, Tony K T La. Hypothalamic glucagon signals through the KATP channels to regulate glucose production. Molecular metabolism. vol 3. issue 2. 2014-03-17. PMID:24634823. |
insulin, leptin and glp-1 signal in the mediobasal hypothalamus (mbh) to lower hepatic glucose production (gp). |
2014-03-17 |
2023-08-12 |
Not clear |
| Karolina P Skibick. The central GLP-1: implications for food and drug reward. Frontiers in neuroscience. vol 7. 2014-02-18. PMID:24133407. |
in accordance with the classical model of food intake control glp-1 action on feeding has been primarily ascribed to receptor populations in the hypothalamus and the hindbrain. |
2014-02-18 |
2023-08-12 |
Not clear |