| Publication |
Sentence |
Publish Date |
Extraction Date |
Species |
| X Jia, J C Brown, P Ma, R A Pederson, C H McIntos. Effects of glucose-dependent insulinotropic polypeptide and glucagon-like peptide-I-(7-36) on insulin secretion. The American journal of physiology. vol 268. issue 4 Pt 1. 1995-06-01. PMID:7733263. |
the effects of natural (np) and synthetic porcine (sp) gip, synthetic human (sh) gip, and glp-i-(7-36) on insulin secretion from the perfused rat pancreas were compared using gradient perfusion. |
1995-06-01 |
2023-08-12 |
human |
| J A Roe, A S Baba, J M Harper, P J Butter. Effects of growth factors and gut regulatory peptides on nutrient uptake in ovine muscle cell cultures. Comparative biochemistry and physiology. Part A, Physiology. vol 110. issue 2. 1995-05-10. PMID:7704622. |
gastrin, gastric inhibitory polypeptide (gip), bombesin and somatostatin had no action in either the absence or presence of insulin. |
1995-05-10 |
2023-08-12 |
cattle |
| Y T Kruszynska, M A Ghatei, S R Bloom, N McIntyr. Insulin secretion and plasma levels of glucose-dependent insulinotropic peptide and glucagon-like peptide 1 [7-36 amide] after oral glucose in cirrhosis. Hepatology (Baltimore, Md.). vol 21. issue 4. 1995-05-09. PMID:7705803. |
oral glucose is a better stimulant to insulin secretion than intravenous (iv) glucose in part because of release of gut peptides, notably glucose-dependent insulinotropic peptide (gip) and glucagon-like peptide 1 [7-36 amide] (glp-1 [7-36 amide]). |
1995-05-09 |
2023-08-12 |
human |
| Y T Kruszynska, M A Ghatei, S R Bloom, N McIntyr. Insulin secretion and plasma levels of glucose-dependent insulinotropic peptide and glucagon-like peptide 1 [7-36 amide] after oral glucose in cirrhosis. Hepatology (Baltimore, Md.). vol 21. issue 4. 1995-05-09. PMID:7705803. |
because impaired release of or resistance to these gut peptides could explain impaired insulin secretion after oral glucose, we measured insulin secretion, plasma gip, and glp-1 [7-36 amide] levels, basally and after 75 g oral glucose, in 10 cirrhotics and 10 controls. |
1995-05-09 |
2023-08-12 |
human |
| J G Schwartz, C A McMahan, G M Green, W T Phillip. Gastric emptying in Mexican Americans compared to non-Hispanic whites. Digestive diseases and sciences. vol 40. issue 3. 1995-04-21. PMID:7895557. |
serum insulin, plasma glucose, and gip levels were measured in fasting and postprandial blood samples collected at 15-min intervals for 2 hr. |
1995-04-21 |
2023-08-12 |
human |
| P J Jones, G L Namchuk, R A Pederso. Meal frequency influences circulating hormone levels but not lipogenesis rates in humans. Metabolism: clinical and experimental. vol 44. issue 2. 1995-03-28. PMID:7869919. |
on day 2 (08:00 h) of each diet period, 0.7 g deuterium (d) oxide/kg body water was administered and blood was collected every 4 hours over 48 hours for measurement of plasma insulin and glucose-dependent insulinotropic polypeptide (gip) levels. |
1995-03-28 |
2023-08-12 |
human |
| P J Jones, G L Namchuk, R A Pederso. Meal frequency influences circulating hormone levels but not lipogenesis rates in humans. Metabolism: clinical and experimental. vol 44. issue 2. 1995-03-28. PMID:7869919. |
insulin and gip levels were elevated over daytime periods in subjects fed three versus six meals per day. |
1995-03-28 |
2023-08-12 |
human |
| R M Elliott, L M Morgan, J A Tredger, S Deacon, J Wright, V Mark. Glucagon-like peptide-1 (7-36)amide and glucose-dependent insulinotropic polypeptide secretion in response to nutrient ingestion in man: acute post-prandial and 24-h secretion patterns. The Journal of endocrinology. vol 138. issue 1. 1995-03-10. PMID:7852887. |
plasma gip, insulin and glucose levels increased after all three meals, the largest increase being observed following glucose and the smallest following the barley meal. |
1995-03-10 |
2023-08-12 |
human |
| F Kolligs, H C Fehmann, R Göke, B Gök. Reduction of the incretin effect in rats by the glucagon-like peptide 1 receptor antagonist exendin (9-39) amide. Diabetes. vol 44. issue 1. 1995-02-07. PMID:7813808. |
in contrast, the glp-1 antagonist left the insulin response after an intravenous glucose or glucose plus gip (60 pmol) load unaltered. |
1995-02-07 |
2023-08-12 |
rat |
| G Varga, T E Adrian, D H Coy, R D Reidelberge. Bombesin receptor subtype mediation of gastroenteropancreatic hormone secretion in rats. Peptides. vol 15. issue 4. 1994-11-22. PMID:7937351. |
bombesin is a potent releaser of many gut and pancreatic hormones including gastrin, glucose-dependent insulinotropic polypeptide (gip), pancreatic polypeptide (pp), cholecystokinin (cck), enteroglucagon, and insulin. |
1994-11-22 |
2023-08-12 |
rat |
| G Varga, T E Adrian, D H Coy, R D Reidelberge. Bombesin receptor subtype mediation of gastroenteropancreatic hormone secretion in rats. Peptides. vol 15. issue 4. 1994-11-22. PMID:7937351. |
we used a highly potent, selective antagonist of the grp-preferring receptor, [d-phe6]bombesine(6-13)-methylester ([d-phe6]bn(6-13)ome), to determine the receptor subtype mediating bombesin-induced secretion of gastrin, gip, pp, peptide yy (pyy), and insulin, as well as the importance of endogenous bombesin-like peptides in controlling basal secretion of these hormones. |
1994-11-22 |
2023-08-12 |
rat |
| G Varga, T E Adrian, D H Coy, R D Reidelberge. Bombesin receptor subtype mediation of gastroenteropancreatic hormone secretion in rats. Peptides. vol 15. issue 4. 1994-11-22. PMID:7937351. |
plasma gastrin, gip, pp, pyy, and insulin were measured by specific radioimmunoassays. |
1994-11-22 |
2023-08-12 |
rat |
| G Varga, T E Adrian, D H Coy, R D Reidelberge. Bombesin receptor subtype mediation of gastroenteropancreatic hormone secretion in rats. Peptides. vol 15. issue 4. 1994-11-22. PMID:7937351. |
[d-phe6]bn(6-13)ome alone reduced basal insulin levels by 28% (p < 0.05) but did not alter basal levels of plasma pp, gip, pyy, or gastrin (p > 0.05 for each). |
1994-11-22 |
2023-08-12 |
rat |
| G Varga, T E Adrian, D H Coy, R D Reidelberge. Bombesin receptor subtype mediation of gastroenteropancreatic hormone secretion in rats. Peptides. vol 15. issue 4. 1994-11-22. PMID:7937351. |
[d-phe6]bn(6-13)ome completely blocked bombesin-induced increases in pp, insulin, and gastrin, and almost completely blocked increases in gip and pyy (p < 0.01 for each). |
1994-11-22 |
2023-08-12 |
rat |
| G Varga, T E Adrian, D H Coy, R D Reidelberge. Bombesin receptor subtype mediation of gastroenteropancreatic hormone secretion in rats. Peptides. vol 15. issue 4. 1994-11-22. PMID:7937351. |
our results suggest that (a) exogenous bombesin significantly stimulates pp, insulin, gip, pyy, and gastrin secretion, (b) bombesin-induced secretion of these hormones is primarily mediated by the grp-preferring receptor, and (c) an endogenous bombesin-like peptide acting at this receptor subtype plays an important physiological role in control of basal secretion of insulin but not pp, gip, pyy, or gastrin. |
1994-11-22 |
2023-08-12 |
rat |
| G R Greenberg, S Pokol-Danie. Neural modulation of glucose-dependent insulinotropic peptide (GIP) and insulin secretion in conscious dogs. Pancreas. vol 9. issue 4. 1994-11-04. PMID:7937701. |
neural modulation of glucose-dependent insulinotropic peptide (gip) and insulin secretion in conscious dogs. |
1994-11-04 |
2023-08-12 |
Not clear |
| G R Greenberg, S Pokol-Danie. Neural modulation of glucose-dependent insulinotropic peptide (GIP) and insulin secretion in conscious dogs. Pancreas. vol 9. issue 4. 1994-11-04. PMID:7937701. |
in four conscious dogs, plasma gip, plasma insulin, and plasma glucose responses were measured after intraduodenal administration of a defined formula diet, after glucose was perfused intraduodenally, and after insulin-mediated hypoglycemia with and without bilateral cryogenic blockade of the cervical vagus nerves. |
1994-11-04 |
2023-08-12 |
Not clear |
| G R Greenberg, S Pokol-Danie. Neural modulation of glucose-dependent insulinotropic peptide (GIP) and insulin secretion in conscious dogs. Pancreas. vol 9. issue 4. 1994-11-04. PMID:7937701. |
intravenous atropine (50 micrograms/kg) did not modify the gip responses to intraduodenal perfusions of the defined formula diet or to glucose, but did suppress plasma insulin responses to baseline values. |
1994-11-04 |
2023-08-12 |
Not clear |
| G R Greenberg, S Pokol-Danie. Neural modulation of glucose-dependent insulinotropic peptide (GIP) and insulin secretion in conscious dogs. Pancreas. vol 9. issue 4. 1994-11-04. PMID:7937701. |
insulin hypoglycemia without or with vagal blockade had no effect on basal concentrations of plasma gip. |
1994-11-04 |
2023-08-12 |
Not clear |
| G R Greenberg, S Pokol-Danie. Neural modulation of glucose-dependent insulinotropic peptide (GIP) and insulin secretion in conscious dogs. Pancreas. vol 9. issue 4. 1994-11-04. PMID:7937701. |
these results indicate that vagal muscarinic and nonvagal muscarinic pathways participate in the control of the intestinal phase of insulin secretion, but the regulation of gip secretion is independent of vagal or muscarinic neural control mechanisms. |
1994-11-04 |
2023-08-12 |
Not clear |