| Publication |
Sentence |
Publish Date |
Extraction Date |
Species |
| M A Nauck, J Siemsglüss, C Orskov, J J Hols. Release of glucagon-like peptide 1 (GLP-1 [7-36 amide]), gastric inhibitory polypeptide (GIP) and insulin in response to oral glucose after upper and lower intestinal resections. Zeitschrift fur Gastroenterologie. vol 34. issue 3. 1996-07-19. PMID:8650968. |
glp-1[7-36 amide], insulin c-peptide, gip and glucagon (specific (rias) were measured over 240 min. |
1996-07-19 |
2023-08-12 |
Not clear |
| N Fukase, H Manaka, K Sugiyama, H Takahashi, M Igarashi, M Daimon, K Yamatani, M Tominaga, H Sasak. Response of truncated glucagon-like peptide-1 and gastric inhibitory polypeptide to glucose ingestion in non-insulin dependent diabetes mellitus. Effect of sulfonylurea therapy. Acta diabetologica. vol 32. issue 3. 1996-04-01. PMID:8590785. |
following ogtt, plasma glucose, gip, glp-1nt, and glp-1ct in type 2 patients increased more markedly than in controls, despite the lower response of insulin. |
1996-04-01 |
2023-08-12 |
human |
| B Thoren. Glucagon-like peptide-1 and control of insulin secretion. Diabete & metabolisme. vol 21. issue 5. 1996-03-27. PMID:8586147. |
gip stimulation of insulin secretion depends on the presence of specific beta-cell receptors and requires glucose at a concentration at least equal to or higher than the normoglycaemic level of approximately 5 mm. |
1996-03-27 |
2023-08-12 |
Not clear |
| Y Yamada, T Hayami, K Nakamura, P J Kaisaki, Y Someya, C Z Wang, S Seino, Y Sein. Human gastric inhibitory polypeptide receptor: cloning of the gene (GIPR) and cDNA. Genomics. vol 29. issue 3. 1996-03-14. PMID:8575774. |
gastric inhibitory polypeptide (gip), which is released from the gastrointestinal tract, stimulates insulin secretion from pancreatic beta cells and plays a crucial role in the regulation of insulin secretion during the postprandial phase. |
1996-03-14 |
2023-08-12 |
human |
| K Moens, H Heimberg, D Flamez, P Huypens, E Quartier, Z Ling, D Pipeleers, S Gremlich, B Thorens, F Schui. Expression and functional activity of glucagon, glucagon-like peptide I, and glucose-dependent insulinotropic peptide receptors in rat pancreatic islet cells. Diabetes. vol 45. issue 2. 1996-02-21. PMID:8549871. |
in conclusion, these data show that stimulation of glucagon, glp-i, and gip receptors in rat beta-cells causes camp production required for insulin release, while adenylate cyclase in alpha-cells is positively regulated by gip. |
1996-02-21 |
2023-08-12 |
rat |
| J Schirra, M Katschinski, C Weidmann, T Schäfer, U Wank, R Arnold, B Gök. Gastric emptying and release of incretin hormones after glucose ingestion in humans. The Journal of clinical investigation. vol 97. issue 1. 1996-02-16. PMID:8550855. |
this study investigated in eight healthy male volunteers (a) the gastric emptying pattern of 50 and 100 grams of glucose; (b) its relation to the phase of interdigestive motility (phase i or ii) existing when glucose was ingested; and (c) the interplay between gastric emptying or duodenal perfusion of glucose (1.1 and 2.2 kcal/min; identical total glucose loads as orally given) and release of glucose-dependent insulinotropic peptide (gip), glucagon-like peptide-1(7-36)amide (glp-1), c-peptide, insulin, and plasma glucose. |
1996-02-16 |
2023-08-12 |
human |
| J Schirra, M Katschinski, C Weidmann, T Schäfer, U Wank, R Arnold, B Gök. Gastric emptying and release of incretin hormones after glucose ingestion in humans. The Journal of clinical investigation. vol 97. issue 1. 1996-02-16. PMID:8550855. |
oral administration of glucose yielded higher glp-1 and insulin releases but an equal gip release compared with the isocaloric duodenal perfusion. |
1996-02-16 |
2023-08-12 |
human |
| H C Fehmann, B Gök. Characterization of GIP(1-30) and GIP(1-42) as stimulators of proinsulin gene transcription. Peptides. vol 16. issue 6. 1996-02-01. PMID:8532600. |
insulin release from rin 1046-38 cells stimulated by both gip forms was identical. |
1996-02-01 |
2023-08-12 |
Not clear |
| H C Fehmann, B Gök. Characterization of GIP(1-30) and GIP(1-42) as stimulators of proinsulin gene transcription. Peptides. vol 16. issue 6. 1996-02-01. PMID:8532600. |
gip not only enhances insulin secretion but also insulin gene expression and, therefore, it is a true insulinotropic hormone. |
1996-02-01 |
2023-08-12 |
Not clear |
| P R Ellis, F G Roberts, A G Low, L M Morga. The effect of high-molecular-weight guar gum on net apparent glucose absorption and net apparent insulin and gastric inhibitory polypeptide production in the growing pig: relationship to rheological changes in jejunal digesta. The British journal of nutrition. vol 74. issue 4. 1995-12-28. PMID:7577892. |
the present study was designed to determine the quantitative effects of starchy meals containing guar gum on rates of net apparent glucose absorption and net apparent insulin and gastric inhibitory polypeptide (gip) production in growing pigs. |
1995-12-28 |
2023-08-12 |
Not clear |
| P R Ellis, F G Roberts, A G Low, L M Morga. The effect of high-molecular-weight guar gum on net apparent glucose absorption and net apparent insulin and gastric inhibitory polypeptide production in the growing pig: relationship to rheological changes in jejunal digesta. The British journal of nutrition. vol 74. issue 4. 1995-12-28. PMID:7577892. |
both concentrations of guar gum significantly reduced (p < 0.05) glucose absorption and insulin and gip secretion rates over the 4 h postprandial period. |
1995-12-28 |
2023-08-12 |
Not clear |
| A Volz, R Göke, B Lankat-Buttgereit, H C Fehmann, H P Bode, B Gök. Molecular cloning, functional expression, and signal transduction of the GIP-receptor cloned from a human insulinoma. FEBS letters. vol 373. issue 1. 1995-11-24. PMID:7589426. |
glucose-dependent insulinotropic polypeptide (gip) plays an important role in the regulation of postprandial insulin secretion and proinsulin gene expression of pancreatic beta-cells. |
1995-11-24 |
2023-08-12 |
human |
| A Zampelas, L M Morgan, N Furlonger, C M William. Effects of dietary fatty acid composition on basal and hormone-stimulated hepatic lipogenesis and on circulating lipids in the rat. The British journal of nutrition. vol 74. issue 3. 1995-11-21. PMID:7547851. |
effects of dietary fatty acid composition on in vitro rates of [u-14c]glucose incorporation into hepatic total lipids and into hepatic triacylglycerol were measured under basal, insulin (4 nm)-, gastric inhibitory polypeptide (gip; 6 nm)- and insulin + gip (4 nm + 6 nm)-stimulated conditions. |
1995-11-21 |
2023-08-12 |
rat |
| A Zampelas, L M Morgan, N Furlonger, C M William. Effects of dietary fatty acid composition on basal and hormone-stimulated hepatic lipogenesis and on circulating lipids in the rat. The British journal of nutrition. vol 74. issue 3. 1995-11-21. PMID:7547851. |
effects of the three diets on postprandial plasma triacylglycerol, cholesterol, insulin and gip concentrations were also measured. |
1995-11-21 |
2023-08-12 |
rat |
| A Zampelas, L M Morgan, N Furlonger, C M William. Effects of dietary fatty acid composition on basal and hormone-stimulated hepatic lipogenesis and on circulating lipids in the rat. The British journal of nutrition. vol 74. issue 3. 1995-11-21. PMID:7547851. |
the presence of insulin + gip in the incubation medium stimulated glucose incorporation into hepatic total lipids in the maize-oil (p < 0.01) and fish-oil groups (p < 0.05), as well as into hepatic triacylglycerol in the maize-oil group (p < 0.005). |
1995-11-21 |
2023-08-12 |
rat |
| S Gremlich, A Porret, E H Hani, D Cherif, N Vionnet, P Froguel, B Thoren. Cloning, functional expression, and chromosomal localization of the human pancreatic islet glucose-dependent insulinotropic polypeptide receptor. Diabetes. vol 44. issue 10. 1995-10-24. PMID:7556958. |
glucose-dependent insulinotropic polypeptide (gip) is a hormone secreted by the endocrine k-cells from the duodenum that stimulates glucose-induced insulin secretion. |
1995-10-24 |
2023-08-12 |
human |
| R Tedde, A Pala, A Melis, G Sechi, F Bilotta, G Reald. Hyperinsulinemia and hypertension. Do intestinal hormones play a role? American journal of hypertension. vol 8. issue 2. 1995-06-29. PMID:7755955. |
plasma glucose, serum insulin (iri), and gip were evaluated after a mixed meal containing a total of 82 g of carbohydrates, and 2 g sodium chloride. |
1995-06-29 |
2023-08-12 |
human |
| P Fieseler, S Bridenbaugh, R Nustede, J Martell, C Orskov, J J Holst, M A Nauc. Physiological augmentation of amino acid-induced insulin secretion by GIP and GLP-I but not by CCK-8. The American journal of physiology. vol 268. issue 5 Pt 1. 1995-06-29. PMID:7762650. |
physiological augmentation of amino acid-induced insulin secretion by gip and glp-i but not by cck-8. |
1995-06-29 |
2023-08-12 |
human |
| P Fieseler, S Bridenbaugh, R Nustede, J Martell, C Orskov, J J Holst, M A Nauc. Physiological augmentation of amino acid-induced insulin secretion by GIP and GLP-I but not by CCK-8. The American journal of physiology. vol 268. issue 5 Pt 1. 1995-06-29. PMID:7762650. |
gip and glp-i-(7--36) amide further stimulated insulin (1.8-fold, p = 0.0001 and 0.004, respectively) and c-peptide (1.3-fold, p = 0.0003 and 0.013, respectively), with a subsequent slight reduction in plasma glucose (p < 0.0001). |
1995-06-29 |
2023-08-12 |
human |
| C Herrmann, R Göke, G Richter, H C Fehmann, R Arnold, B Gök. Glucagon-like peptide-1 and glucose-dependent insulin-releasing polypeptide plasma levels in response to nutrients. Digestion. vol 56. issue 2. 1995-06-22. PMID:7750665. |
in response to an intraduodenal infusion of a small glucose load (5.34 g within 120 min) a rapid, short-lasting glp-1 response occurred whereas plasma gip and insulin levels remained unaltered. |
1995-06-22 |
2023-08-12 |
human |