| Publication |
Sentence |
Publish Date |
Extraction Date |
Species |
| L Morgan, J Arendt, D Owens, S Folkard, S Hampton, S Deacon, J English, D Ribeiro, K Taylo. Effects of the endogenous clock and sleep time on melatonin, insulin, glucose and lipid metabolism. The Journal of endocrinology. vol 157. issue 3. 1998-08-10. PMID:9691977. |
during each cr salivary melatonin and plasma glucose, triacylglycerol (tag), non-essential fatty acids (nefa), insulin, gastric inhibitory peptide (gip) and glucagon-like peptide-1 (glp-1) were measured hourly. |
1998-08-10 |
2023-08-12 |
human |
| N N Kok, L M Morgan, C M Williams, M B Roberfroid, J P Thissen, N M Delzenn. Insulin, glucagon-like peptide 1, glucose-dependent insulinotropic polypeptide and insulin-like growth factor I as putative mediators of the hypolipidemic effect of oligofructose in rats. The Journal of nutrition. vol 128. issue 7. 1998-07-23. PMID:9649591. |
because glucose, insulin, insulin-like growth factor i (igf-i) and gut peptides [i.e., glucose-dependent insulinotropic polypeptide (gip) and glucagon-like peptide-1 (glp-1)]) are factors involved in the metabolic response to nutrients, this paper analyzes their putative role in the hypolipidemic effect of oligofructose. |
1998-07-23 |
2023-08-12 |
rat |
| N N Kok, L M Morgan, C M Williams, M B Roberfroid, J P Thissen, N M Delzenn. Insulin, glucagon-like peptide 1, glucose-dependent insulinotropic polypeptide and insulin-like growth factor I as putative mediators of the hypolipidemic effect of oligofructose in rats. The Journal of nutrition. vol 128. issue 7. 1998-07-23. PMID:9649591. |
male wistar rats were fed a nonpurified diet with or without 10% oligofructose for 30 d. glucose, insulin, igf-i and gip concentrations were measured in the serum of rats after eating. |
1998-07-23 |
2023-08-12 |
rat |
| R A Pederson, M Satkunarajah, C H McIntosh, L A Scrocchi, D Flamez, F Schuit, D J Drucker, M B Wheele. Enhanced glucose-dependent insulinotropic polypeptide secretion and insulinotropic action in glucagon-like peptide 1 receptor -/- mice. Diabetes. vol 47. issue 7. 1998-07-10. PMID:9648827. |
furthermore, gip perfusion of mice pancreas and isolated islets in the presence of elevated glucose concentrations elicited a significantly greater insulin response in glp-1r -/- than in +/+ mice (p < or = 0.02-0.05). |
1998-07-10 |
2023-08-12 |
mouse |
| L Ranganath, F Norris, L Morgan, J Wright, V Mark. Delayed gastric emptying occurs following acarbose administration and is a further mechanism for its anti-hyperglycaemic effect. Diabetic medicine : a journal of the British Diabetic Association. vol 15. issue 2. 1998-04-14. PMID:9507911. |
peak plasma glucose, insulin, and glucose-dependent insulinotropic polypeptide (gip) responses were reduced when sucrose was given with acarbose. |
1998-04-14 |
2023-08-12 |
human |
| A M Svensson, S Efendic, C G Ostenson, L Jansso. Gastric inhibitory polypeptide and splanchnic blood perfusion: augmentation of the islet blood flow increase in hyperglycemic rats. Peptides. vol 18. issue 7. 1998-01-05. PMID:9357066. |
both doses of gip potentiated basal and glucose-stimulated insulin release. |
1998-01-05 |
2023-08-12 |
rat |
| D Gefel, Y Barg, R Zimlichma. Glucagon-like peptide-1 structure, function and potential use for NIDDM. Israel journal of medical sciences. vol 33. issue 10. 1997-12-31. PMID:9397146. |
glp-1 and gastric inhibitory peptide (gip) which has also been termed glucose-dependent insulinotropic peptide appear to account for most of the incretin effect in the augmentation of glucose-stimulated insulin secretion. |
1997-12-31 |
2023-08-12 |
Not clear |
| R Gama, F Norris, L Morgan, S Hampton, J Wright, V Mark. Elevated post-prandial gastric inhibitory polypeptide concentrations in hypertriglyceridaemic subjects. Clinical science (London, England : 1979). vol 93. issue 4. 1997-12-29. PMID:9404226. |
serum triglycerides and plasma glucose gip, glp-1 and immunoreactive insulin (iri) concentrations were measured before and after a mixed meal in 15 hypertriglyceridaemic patients and in eight healthy normotriglyceridaemic control subjects. |
1997-12-29 |
2023-08-12 |
human |
| R Gama, F Norris, L Morgan, S Hampton, J Wright, V Mark. Elevated post-prandial gastric inhibitory polypeptide concentrations in hypertriglyceridaemic subjects. Clinical science (London, England : 1979). vol 93. issue 4. 1997-12-29. PMID:9404226. |
we found no association between gip and insulin. |
1997-12-29 |
2023-08-12 |
human |
| J Pierluissi, R M de Pierluiss. Effect of glucose-dependent insulinotropic polypeptide (GIP) on insulin response to glucose in acromegalics. Acta cientifica venezolana. vol 46. issue 2. 1997-12-08. PMID:9279024. |
effect of glucose-dependent insulinotropic polypeptide (gip) on insulin response to glucose in acromegalics. |
1997-12-08 |
2023-08-12 |
human |
| M P van der Burg, P T van Suylichem, O R Guicherit, M Frölich, H H Lemkes, H G Goosze. Glucoregulation after canine islet transplantation: contribution of insulin secretory capacity, insulin action, and the entero-insular axis. Cell transplantation. vol 6. issue 5. 1997-11-14. PMID:9331501. |
infusion of gip had no effect, but glp-1 nearly doubled glucose-stimulated insulin. |
1997-11-14 |
2023-08-12 |
human |
| M A Nauck, J J Holst, B Willms, W Schmiege. Glucagon-like peptide 1 (GLP-1) as a new therapeutic approach for type 2-diabetes. Experimental and clinical endocrinology & diabetes : official journal, German Society of Endocrinology [and] German Diabetes Association. vol 105. issue 4. 1997-10-02. PMID:9285204. |
enprostil, a prostaglandin e2 analogue, fully suppresses gip responses, while only marginally affecting insulin secretion and glucose tolerance after oral glucose, suggesting compensatory hypersecretion of additional insulinotropic peptides, possibly including glp-1. |
1997-10-02 |
2023-08-12 |
Not clear |
| R W Gelling, D H Coy, R A Pederson, M B Wheeler, S Hinke, T Kwan, C H McIntos. GIP(6-30amide) contains the high affinity binding region of GIP and is a potent inhibitor of GIP1-42 action in vitro. Regulatory peptides. vol 69. issue 3. 1997-09-22. PMID:9226399. |
gip (glucose-dependent insulinotropic polypeptide) is an important regulator of insulin secretion. |
1997-09-22 |
2023-08-12 |
Not clear |
| B Ahrén, H Larsson, J J Hols. Reduced gastric inhibitory polypeptide but normal glucagon-like peptide 1 response to oral glucose in postmenopausal women with impaired glucose tolerance. European journal of endocrinology. vol 137. issue 2. 1997-09-17. PMID:9272099. |
the gastrointestinal hormones, gastric inhibitory polypeptide (gip) and glucagon-like peptide 1 (glp-1), are both released from the gut after oral glucose ingestion and stimulate insulin secretion. |
1997-09-17 |
2023-08-12 |
human |
| M O Boylan, L I Jepeal, L A Jarboe, M M Wolf. Cell-specific expression of the glucose-dependent insulinotropic polypeptide gene in a mouse neuroendocrine tumor cell line. The Journal of biological chemistry. vol 272. issue 28. 1997-08-14. PMID:9211887. |
glucose-dependent insulinotropic polypeptide (gip) is a 42-amino acid gastrointestinal regulatory peptide that, in the presence of glucose, stimulates insulin secretion. |
1997-08-14 |
2023-08-12 |
mouse |
| Y Miura, M Kato, K Ogino, H Matsu. Impaired cytosolic Ca2+ response to glucose and gastric inhibitory polypeptide in pancreatic beta-cells from triphenyltin-induced diabetic hamster. Endocrinology. vol 138. issue 7. 1997-07-24. PMID:9202216. |
in the present study, to test the possibility that the impaired insulin secretion induced by triphenyltin compounds could result from an impaired ca2+ response in pancreatic beta-cells, we investigated the effect of triphenyltin-chloride (tptcl) administration on the changes in the cytoplasmic ca2+ concentration ([ca2+]i) induced by secretagogues, such as glucose, high k+, gastric inhibitory polypeptide (gip), and acetylcholine (ach) in hamster pancreatic beta-cells. |
1997-07-24 |
2023-08-12 |
Not clear |
| Y Miura, M Kato, K Ogino, H Matsu. Impaired cytosolic Ca2+ response to glucose and gastric inhibitory polypeptide in pancreatic beta-cells from triphenyltin-induced diabetic hamster. Endocrinology. vol 138. issue 7. 1997-07-24. PMID:9202216. |
tptcl administration also impaired the insulin secretion in islet cells induced by 27.8 mm glucose, 100 nm gip in the presence of 5.5 mm glucose, and 100 microm ach in the presence of 5.5 mm glucose (p < 0.05, n = 9-16). |
1997-07-24 |
2023-08-12 |
Not clear |
| C Limb, W V Tamborlane, R S Sherwin, R Pederson, S Capri. Acute incretin response to oral glucose is associated with stimulation of gastric inhibitory polypeptide, not glucagon-like peptide in young subjects. Pediatric research. vol 41. issue 3. 1997-07-01. PMID:9078536. |
the time course of the rise in plasma gip and insulin was nearly identical. |
1997-07-01 |
2023-08-12 |
human |
| C Limb, W V Tamborlane, R S Sherwin, R Pederson, S Capri. Acute incretin response to oral glucose is associated with stimulation of gastric inhibitory polypeptide, not glucagon-like peptide in young subjects. Pediatric research. vol 41. issue 3. 1997-07-01. PMID:9078536. |
we conclude that the gip response to a modest oral glucose load may play an important physiologic role in glucose-stimulated insulin secretion in healthy young subjects. |
1997-07-01 |
2023-08-12 |
human |
| W G Ding, E Renström, P Rorsman, K Buschard, J Gromad. Glucagon-like peptide I and glucose-dependent insulinotropic polypeptide stimulate Ca2+-induced secretion in rat alpha-cells by a protein kinase A-mediated mechanism. Diabetes. vol 46. issue 5. 1997-05-28. PMID:9133546. |
the islet hormone somatostatin inhibited the stimulatory action of glp-i(7-36) amide and gip via a cyclic amp-independent mechanism, whereas insulin had no effect on exocytosis. |
1997-05-28 |
2023-08-12 |
rat |