| Publication |
Sentence |
Publish Date |
Extraction Date |
Species |
| S J Gatenby, P R Ellis, L M Morgan, P A Jud. Effect of partially depolymerized guar gum on acute metabolic variables in patients with non-insulin-dependent diabetes. Diabetic medicine : a journal of the British Diabetic Association. vol 13. issue 4. 1997-05-27. PMID:9162612. |
guar gum bread significantly reduced the postprandial rise in blood glucose, plasma insulin, and, except for bread containing low mw guar gum, plasma gip levels compared to the control. |
1997-05-27 |
2023-08-12 |
Not clear |
| W G Ding, J Gromad. Protein kinase A-dependent stimulation of exocytosis in mouse pancreatic beta-cells by glucose-dependent insulinotropic polypeptide. Diabetes. vol 46. issue 4. 1997-04-25. PMID:9075801. |
the mechanisms by which glucose-dependent insulinotropic polypeptide (gip) stimulates insulin secretion were investigated by measurements of whole-cell ca2+ currents, the cytoplasmic ca2+ concentration, and cell capacitance as an indicator of exocytosis in individual mouse pancreatic beta-cells maintained in short-term culture. |
1997-04-25 |
2023-08-12 |
mouse |
| W G Ding, J Gromad. Protein kinase A-dependent stimulation of exocytosis in mouse pancreatic beta-cells by glucose-dependent insulinotropic polypeptide. Diabetes. vol 46. issue 4. 1997-04-25. PMID:9075801. |
collectively, our data indicate that the insulinotropic hormone gip stimulates insulin secretion from pancreatic beta-cells, through the camp/pka signaling pathway, by interacting with the secretory machinery at a level distal to an elevation in [ca2+]i. |
1997-04-25 |
2023-08-12 |
mouse |
| J Gómez-Cerezo, M C Garcés, R Codoceo, A Soto, F Arnalich, J Barbado, J J Vázque. Postprandial glucose-dependent insulinotropic polypeptide and insulin responses in patients with chronic pancreatitis with and without secondary diabetes. Regulatory peptides. vol 67. issue 3. 1997-04-09. PMID:8988521. |
to study gip and insulin release after a test meal in patients with chronic pancreatitis with and without secondary diabetes mellitus. |
1997-04-09 |
2023-08-12 |
Not clear |
| M L Doong, J W Wang, S C Chung, J Y Liu, C Hwang, C Y Hwang, C H Day, Y F Liu, T K Young, L L Ho, P S Wan. Regulation of thyroid hormones in the secretion of insulin and gastric inhibitory polypeptide in male rats. Metabolism: clinical and experimental. vol 46. issue 2. 1997-03-04. PMID:9030821. |
the effect of thyroid hormones on glucose-induced secretion of gastric inhibitory polypeptide (gip) and insulin was studied. |
1997-03-04 |
2023-08-12 |
rat |
| M L Doong, J W Wang, S C Chung, J Y Liu, C Hwang, C Y Hwang, C H Day, Y F Liu, T K Young, L L Ho, P S Wan. Regulation of thyroid hormones in the secretion of insulin and gastric inhibitory polypeptide in male rats. Metabolism: clinical and experimental. vol 46. issue 2. 1997-03-04. PMID:9030821. |
plasma levels of gip and insulin were measured by specific radioimmunoassays (rias). |
1997-03-04 |
2023-08-12 |
rat |
| M L Doong, J W Wang, S C Chung, J Y Liu, C Hwang, C Y Hwang, C H Day, Y F Liu, T K Young, L L Ho, P S Wan. Regulation of thyroid hormones in the secretion of insulin and gastric inhibitory polypeptide in male rats. Metabolism: clinical and experimental. vol 46. issue 2. 1997-03-04. PMID:9030821. |
thyroidectomy-induced hypothyroidism increased the basal level of plasma gip, but decreased that of insulin. |
1997-03-04 |
2023-08-12 |
rat |
| M L Doong, J W Wang, S C Chung, J Y Liu, C Hwang, C Y Hwang, C H Day, Y F Liu, T K Young, L L Ho, P S Wan. Regulation of thyroid hormones in the secretion of insulin and gastric inhibitory polypeptide in male rats. Metabolism: clinical and experimental. vol 46. issue 2. 1997-03-04. PMID:9030821. |
furthermore, glucose-stimulated insulin secretion was unaltered by pretreatment with t3, whereas the glucose-induced increase in plasma gip was completely abolished by preinjection of t3 in thyroid-intact rats. |
1997-03-04 |
2023-08-12 |
rat |
| M L Doong, J W Wang, S C Chung, J Y Liu, C Hwang, C Y Hwang, C H Day, Y F Liu, T K Young, L L Ho, P S Wan. Regulation of thyroid hormones in the secretion of insulin and gastric inhibitory polypeptide in male rats. Metabolism: clinical and experimental. vol 46. issue 2. 1997-03-04. PMID:9030821. |
these results suggest that thyroid functions are involved in the regulation of insulin and gip secretion in rats. |
1997-03-04 |
2023-08-12 |
rat |
| R Gama, F Norris, J Wright, L Morgan, S Hampton, S Watkins, V Mark. The entero-insular axis in polycystic ovarian syndrome. Annals of clinical biochemistry. vol 33 ( Pt 3). 1997-02-27. PMID:8791980. |
we measured plasma glucose, gastric inhibitory polypeptide (gip), glucagon-like peptide-1 (7-36 amide) (glp-1(7-36) amide), immunoreactive insulin (iri), intact proinsulin (ipi), and c-peptide concentrations during a 75 g oral glucose tolerance test in seven normal weight women with pcos and eight healthy women. |
1997-02-27 |
2023-08-12 |
human |
| B Gallwitz, M Witt, C Morys-Wortmann, U R Fölsch, W E Schmid. GLP-1/GIP chimeric peptides define the structural requirements for specific ligand-receptor interaction of GLP-1. Regulatory peptides. vol 63. issue 1. 1997-02-13. PMID:8795084. |
the gastrointestinal hormones glucagon-like peptide-1 (glp-1) and gastric inhibitory polypeptide (gip) strongly stimulate insulin release. |
1997-02-13 |
2023-08-12 |
Not clear |
| C C Tseng, T J Kieffer, L A Jarboe, T B Usdin, M M Wolf. Postprandial stimulation of insulin release by glucose-dependent insulinotropic polypeptide (GIP). Effect of a specific glucose-dependent insulinotropic polypeptide receptor antagonist in the rat. The Journal of clinical investigation. vol 98. issue 11. 1997-01-23. PMID:8958204. |
postprandial stimulation of insulin release by glucose-dependent insulinotropic polypeptide (gip). |
1997-01-23 |
2023-08-12 |
rat |
| C C Tseng, T J Kieffer, L A Jarboe, T B Usdin, M M Wolf. Postprandial stimulation of insulin release by glucose-dependent insulinotropic polypeptide (GIP). Effect of a specific glucose-dependent insulinotropic polypeptide receptor antagonist in the rat. The Journal of clinical investigation. vol 98. issue 11. 1997-01-23. PMID:8958204. |
glucose-dependent insulinotropic polypeptide (gip) is a 42-amino acid peptide produced by k cells of the mammalian proximal small intestine and is a potent stimulant of insulin release in the presence of hyperglycemia. |
1997-01-23 |
2023-08-12 |
rat |
| C C Tseng, T J Kieffer, L A Jarboe, T B Usdin, M M Wolf. Postprandial stimulation of insulin release by glucose-dependent insulinotropic polypeptide (GIP). Effect of a specific glucose-dependent insulinotropic polypeptide receptor antagonist in the rat. The Journal of clinical investigation. vol 98. issue 11. 1997-01-23. PMID:8958204. |
in fasted anesthetized rats, gip (1-42) stimulated insulin release in a concentration-dependent manner, an effect abolished by the concomitant intraperitoneal administration of gip (7-30)-nh2 (100 nmol/ kg). |
1997-01-23 |
2023-08-12 |
rat |
| C C Tseng, T J Kieffer, L A Jarboe, T B Usdin, M M Wolf. Postprandial stimulation of insulin release by glucose-dependent insulinotropic polypeptide (GIP). Effect of a specific glucose-dependent insulinotropic polypeptide receptor antagonist in the rat. The Journal of clinical investigation. vol 98. issue 11. 1997-01-23. PMID:8958204. |
in contrast, glucose-, glp-1-, and arginine-stimulated insulin release were not affected by gip (7-30)-nh2. |
1997-01-23 |
2023-08-12 |
rat |
| C C Tseng, T J Kieffer, L A Jarboe, T B Usdin, M M Wolf. Postprandial stimulation of insulin release by glucose-dependent insulinotropic polypeptide (GIP). Effect of a specific glucose-dependent insulinotropic polypeptide receptor antagonist in the rat. The Journal of clinical investigation. vol 98. issue 11. 1997-01-23. PMID:8958204. |
in separate experiments, gip (7-30)-nh2 (100 nmol/kg) reduced postprandial insulin release in conscious rats by 72%. |
1997-01-23 |
2023-08-12 |
rat |
| C C Tseng, T J Kieffer, L A Jarboe, T B Usdin, M M Wolf. Postprandial stimulation of insulin release by glucose-dependent insulinotropic polypeptide (GIP). Effect of a specific glucose-dependent insulinotropic polypeptide receptor antagonist in the rat. The Journal of clinical investigation. vol 98. issue 11. 1997-01-23. PMID:8958204. |
it is concluded that gip (7-30)-nh2 is a gip-specific receptor antagonist and that gip plays a dominant role in mediating postprandial insulin release. |
1997-01-23 |
2023-08-12 |
rat |
| S M Hampton, L M Morgan, N Lawrence, T Anastasiadou, F Norris, S Deacon, D Ribeiro, J Arend. Postprandial hormone and metabolic responses in simulated shift work. The Journal of endocrinology. vol 151. issue 2. 1997-01-02. PMID:8958786. |
plasma glucose, insulin, glucose-dependent insulinotropic polypeptide (gip), glucagon-like peptide-1 (glp-1), triacylglycerol (tag) and non-esterified fatty acids (nefas) were determined at intervals for 6 h after each test meal. |
1997-01-02 |
2023-08-12 |
human |
| S M Hampton, L M Morgan, N Lawrence, T Anastasiadou, F Norris, S Deacon, D Ribeiro, J Arend. Postprandial hormone and metabolic responses in simulated shift work. The Journal of endocrinology. vol 151. issue 2. 1997-01-02. PMID:8958786. |
postprandial plasma glucose, insulin, gip and glp-1 profiles were evaluated by calculating areas under the curve (auc) for the first 2 h and the last 4 h of the sampling together with total auc. |
1997-01-02 |
2023-08-12 |
human |
| K Yasuda, Y Sein. [Gastric inhibitory polypeptide (GIP) and GIP receptor (GIPR)]. Nihon rinsho. Japanese journal of clinical medicine. vol 54. issue 4. 1996-12-31. PMID:8920677. |
in vivo and in vitro experiments have indicated that gip auguments glucose-stimulated insulin secretion, suggesting that gip plays an important role in the regulation of insulin secretion as an incretin. |
1996-12-31 |
2023-08-12 |
rat |