| Publication |
Sentence |
Publish Date |
Extraction Date |
Species |
| Ashley I Taylor, Nigel Irwin, Aine M McKillop, Steven Patterson, Peter R Flatt, Victor A Gaul. Evaluation of the degradation and metabolic effects of the gut peptide xenin on insulin secretion, glycaemic control and satiety. The Journal of endocrinology. vol 207. issue 1. 2010-10-12. PMID:20631047. |
xenin also exerted an additive effect on gip, glp1 and neurotensin-mediated insulin secretion. |
2010-10-12 |
2023-08-12 |
mouse |
| Seema Hooda, J Jacques Matte, Thavaratnam Vasanthan, Ruurd T Zijlstr. Dietary oat beta-glucan reduces peak net glucose flux and insulin production and modulates plasma incretin in portal-vein catheterized grower pigs. The Journal of nutrition. vol 140. issue 9. 2010-09-16. PMID:20660287. |
net glucose and scfa flux and insulin secretion into the portal vein might be associated with the incretins glucose-dependent insulinotropic polypeptide (gip) and glucagon-like peptide-1 (glp-1). |
2010-09-16 |
2023-08-12 |
Not clear |
| Seema Hooda, J Jacques Matte, Thavaratnam Vasanthan, Ruurd T Zijlstr. Dietary oat beta-glucan reduces peak net glucose flux and insulin production and modulates plasma incretin in portal-vein catheterized grower pigs. The Journal of nutrition. vol 140. issue 9. 2010-09-16. PMID:20660287. |
in conclusion, dietary supplementation of 6% oat beta-glucan concentrate decreased net glucose flux, increased net scfa flux, and decreased peak apparent insulin production, changes that were associated with gip and glp-1 mediation. |
2010-09-16 |
2023-08-12 |
Not clear |
| Divya Sugunan, Anup K Nair, Harish Kumar, Anilkumar Gopalakrishnapilla. A case-control analysis of common variants in GIP with type 2 diabetes and related biochemical parameters in a South Indian population. BMC medical genetics. vol 11. 2010-09-03. PMID:20673334. |
glucose-dependent insulinotropic polypeptide (gip) is one of the incretins, which plays a crucial role in the secretion of insulin upon food stimulus and in the regulation of postprandial glucose level. |
2010-09-03 |
2023-08-12 |
Not clear |
| Burton M Wice, Songyan Wang, Dan L Crimmins, Kelly A Diggs-Andrews, Matthew C Althage, Eric L Ford, Hung Tran, Matthew Ohlendorf, Terry A Griest, Qiuling Wang, Simon J Fisher, Jack H Ladenson, Kenneth S Polonsk. Xenin-25 potentiates glucose-dependent insulinotropic polypeptide action via a novel cholinergic relay mechanism. The Journal of biological chemistry. vol 285. issue 26. 2010-08-24. PMID:20421298. |
the intestinal peptides glp-1 and gip potentiate glucose-mediated insulin release. |
2010-08-24 |
2023-08-12 |
mouse |
| Burton M Wice, Songyan Wang, Dan L Crimmins, Kelly A Diggs-Andrews, Matthew C Althage, Eric L Ford, Hung Tran, Matthew Ohlendorf, Terry A Griest, Qiuling Wang, Simon J Fisher, Jack H Ladenson, Kenneth S Polonsk. Xenin-25 potentiates glucose-dependent insulinotropic polypeptide action via a novel cholinergic relay mechanism. The Journal of biological chemistry. vol 285. issue 26. 2010-08-24. PMID:20421298. |
like humans with t2dm, "gip/dt" animals exhibited a normal insulin secretory response to exogenous glp-1 but a blunted response to gip. |
2010-08-24 |
2023-08-12 |
mouse |
| Marzieh Salehi, Benedict Aulinger, Ronald L Prigeon, David A D'Alessi. Effect of endogenous GLP-1 on insulin secretion in type 2 diabetes. Diabetes. vol 59. issue 6. 2010-08-10. PMID:20215429. |
the incretins glucagon-like peptide-1 (glp-1) and glucose-dependent insulinotropic polypeptide (gip) account for up to 60% of postprandial insulin release in healthy people. |
2010-08-10 |
2023-08-12 |
Not clear |
| Ruby L C Hoo, Jessica Y S Chu, Y Yuan, C M Yeung, Kathy Y Y Chan, Billy K C Cho. Functional identification of an intronic promoter of the human glucose-dependent insulinotropic polypeptide gene. Gene. vol 463. issue 1-2. 2010-08-03. PMID:20452407. |
glucose-dependent insulinotropic polypeptide (gip), a physiological incretin and enterogastrone, plays a vital role in regulating glucose-dependent insulin release from the pancreas and gastric acid secretion from the stomach. |
2010-08-03 |
2023-08-12 |
mouse |
| Samuel Grossma. Differentiating incretin therapies based on structure, activity, and metabolism: focus on liraglutide. Pharmacotherapy. vol 29. issue 12 Pt 2. 2010-08-02. PMID:19947814. |
the incretin effect, mediated by glucagon-like peptide-1 (glp-1) and glucose-dependent insulinotropic polypeptide (gip), plays an important role in the regulation of insulin secretion in response to oral glucose. |
2010-08-02 |
2023-08-12 |
Not clear |
| Brian Furman, Wee Kiat Ong, Nigel J Pyn. Cyclic AMP signaling in pancreatic islets. Advances in experimental medicine and biology. vol 654. 2010-06-24. PMID:20217503. |
cyclic 3'5'amp (camp) is an important physiological amplifier of glucose-induced insulin secretion by the pancreatic islet beta-cell, where it is formed by the activity of adenylyl cyclases, which are stimulated by glucose, through elevation in intracellular calcium concentrations, and by the incretin hormones (glp-1 and gip). |
2010-06-24 |
2023-08-12 |
Not clear |
| Paul Lidder, Daniel Flanagan, Simon Fleming, Mark Russell, Noel Morgan, Tim Wheatley, Jo Rahamin, Steve Shaw, Stephen Lewi. Combining enteral with parenteral nutrition to improve postoperative glucose control. The British journal of nutrition. vol 103. issue 11. 2010-06-18. PMID:20211036. |
differences between the two intervention groups were assessed for continuous glucose measurement, insulin sensitivity using insulin tolerance tests (itt) and homeostasis model analysis (homa), the incretin glucose-dependent insulinotropic polypeptide (gip) and intestinal permeability. |
2010-06-18 |
2023-08-12 |
Not clear |
| Paul Lidder, Daniel Flanagan, Simon Fleming, Mark Russell, Noel Morgan, Tim Wheatley, Jo Rahamin, Steve Shaw, Stephen Lewi. Combining enteral with parenteral nutrition to improve postoperative glucose control. The British journal of nutrition. vol 103. issue 11. 2010-06-18. PMID:20211036. |
the combination of pn with en resulted in lower interstitial glucose concentrations (p = 0.002), reduced insulin resistance, improved insulin sensitivity (homa-insulin resistance (ir) p = 0.045; homa beta p = 0.037; itt p = 0.006), improved intestinal permeability (p < 0.001) and increased gip (p = 0.01) when compared with pn alone. |
2010-06-18 |
2023-08-12 |
Not clear |
| Giovanni Pacini, Karl Thomaseth, Bo Ahré. Dissociated effects of glucose-dependent insulinotropic polypeptide vs glucagon-like peptide-1 on beta-cell secretion and insulin clearance in mice. Metabolism: clinical and experimental. vol 59. issue 7. 2010-06-17. PMID:20153002. |
glucagon-like peptide-1 (glp-1) and glucose-dependent insulinotropic polypeptide (gip) potently augment insulin response to glucose. |
2010-06-17 |
2023-08-12 |
mouse |
| Giovanni Pacini, Karl Thomaseth, Bo Ahré. Dissociated effects of glucose-dependent insulinotropic polypeptide vs glucagon-like peptide-1 on beta-cell secretion and insulin clearance in mice. Metabolism: clinical and experimental. vol 59. issue 7. 2010-06-17. PMID:20153002. |
the aims of this study were the quantification of c-peptide secretion and the evaluation of insulin clearance after administration of gip with glucose. |
2010-06-17 |
2023-08-12 |
mouse |
| Giovanni Pacini, Karl Thomaseth, Bo Ahré. Dissociated effects of glucose-dependent insulinotropic polypeptide vs glucagon-like peptide-1 on beta-cell secretion and insulin clearance in mice. Metabolism: clinical and experimental. vol 59. issue 7. 2010-06-17. PMID:20153002. |
insulin clearance, previously shown to be abridged by 46% with glp-1, was reduced only by a nonsignificant (p = .27) 21% with gip. |
2010-06-17 |
2023-08-12 |
mouse |
| Giovanni Pacini, Karl Thomaseth, Bo Ahré. Dissociated effects of glucose-dependent insulinotropic polypeptide vs glucagon-like peptide-1 on beta-cell secretion and insulin clearance in mice. Metabolism: clinical and experimental. vol 59. issue 7. 2010-06-17. PMID:20153002. |
insulin clearance with gip is not significantly reduced. |
2010-06-17 |
2023-08-12 |
mouse |
| Norio Harada, Nobuya Inagak. [Incretin and incretin-based therapies]. Nihon rinsho. Japanese journal of clinical medicine. vol 68. issue 5. 2010-05-27. PMID:20446595. |
gip and glp-1 potentiate glucose-induced insulin secretion by binding gip receptor and glp-1 receptor, respectively, on pancreatic beta-cell and increasing intracellular camp concentration (incretin effect). |
2010-05-27 |
2023-08-12 |
human |
| Norio Harada, Nobuya Inagak. [Incretin and incretin-based therapies]. Nihon rinsho. Japanese journal of clinical medicine. vol 68. issue 5. 2010-05-27. PMID:20446595. |
gip and glp-1 have not only pancreatic effect, such as potentiation of insulin secretion, but also many extrapancreatic effects. |
2010-05-27 |
2023-08-12 |
human |
| Yukihiro Fujita, Rhonda D Wideman, Ali Asadi, Gary K Yang, Robert Baker, Travis Webber, Tianjiao Zhang, Rennian Wang, Ziliang Ao, Garth L Warnock, Yin Nam Kwok, Timothy J Kieffe. Glucose-dependent insulinotropic polypeptide is expressed in pancreatic islet alpha-cells and promotes insulin secretion. Gastroenterology. vol 138. issue 5. 2010-05-07. PMID:20138041. |
glucose-dependent insulinotropic polypeptide (gip) and the proglucagon product glucagon-like peptide-1 (glp-1) are gastrointestinal hormones that are released in response to nutrient intake and promote insulin secretion. |
2010-05-07 |
2023-08-12 |
Not clear |
| Georgios Valsamakis, Alexandra Margeli, Nikolaos Vitoratos, Anastassios Boutsiadis, Evangelos G Sakkas, George Papadimitriou, Nasser M Al-Daghri, Dimitrios Botsis, Sudhesh Kumar, Ioannis Papassotiriou, George Creatsas, George Mastorako. The role of maternal gut hormones in normal pregnancy: fasting plasma active glucagon-like peptide 1 level is a negative predictor of fetal abdomen circumference and maternal weight change. European journal of endocrinology. vol 162. issue 5. 2010-05-07. PMID:20194524. |
gut peptides (glucagon-like peptide 1 (glp1), glucose-dependent insulinotropic peptide (gip), ghrelin, and peptide yy (pyy)) have been related to insulin sensitivity and secretion, weight control, and adipose tissue metabolism. |
2010-05-07 |
2023-08-12 |
Not clear |