| Publication |
Sentence |
Publish Date |
Extraction Date |
Species |
| Meena Asmar, Ali Asmar, Lene Simonsen, Flemming Dela, Jens Juul Holst, Jens Bülo. GIP-induced vasodilation in human adipose tissue involves capillary recruitment. Endocrine connections. vol 8. issue 6. 2020-09-28. PMID:31063975. |
eight lean healthy volunteers were studied before and after 1 h infusion of gip or saline during a hyperglycemic-hyperinsulinemic clamp, raising plasma glucose and insulin to postprandial levels. |
2020-09-28 |
2023-08-13 |
human |
| Akiko Taira, Emiko Arita, Eriko Matsumoto, Ayano Oohira, Katsuro Iwase, Takaki Hiwasa, Koutaro Yokote, Shigenobu Shibata, Masaki Takiguch. Systemic oscillator-driven and nutrient-responsive hormonal regulation of daily expression rhythms for gluconeogenic enzyme genes in the mouse liver. Chronobiology international. vol 36. issue 5. 2020-08-21. PMID:30714432. |
in addition to prolonged fasting, a high-fat diet and a high-carbohydrate (no-protein) diet caused modification of daily expression rhythms of the genes, with characteristic changes in profiles of glucoregulatory hormones such as corticosterone, glucagon, and insulin, as well as their modulators including ghrelin, leptin, resistin, glucose-dependent insulinotropic polypeptide (gip), and glucagon-like peptide-1 (glp-1). |
2020-08-21 |
2023-08-13 |
mouse |
| Yanjiao Zhang, Runqing Xiang, Shandan Fang, Kuan Huang, Yuan Fan, Tao Li. Experimental Study on the Effect of Tibetan Medicine Triphala on the Proliferation and Apoptosis of Pancreatic Islet β Cells through Incretin-cAMP Signaling Pathway. Biological & pharmaceutical bulletin. vol 43. issue 2. 2020-08-04. PMID:31813891. |
compared with the model group, in the treatment group, blood glucose decreased, body weight increased, incretin-camp signaling pathway related factors glucose-dependent insulin-promoting polypeptide (gip), glucagon-like peptide-1 (glp-1), glp-1r, camp, p-protein kinase a (pka), akt were up-regulated, insulin secretion was increased, liporing protein interaction protein (txnip) expression was down-regulated. |
2020-08-04 |
2023-08-13 |
rat |
| Christian Zinck Jensen, Kirstine N Bojsen-Møller, Maria S Svane, Line M Holst, Kjeld Hermansen, Bolette Hartmann, Nicolai Jacob Wewer Albrechtsen, Rune Ehrenreich Kuhre, Viggo B Kristiansen, Jens Frederik Rehfeld, Trine R Clausen, Jens J Holst, Sten Madsba. Responses of gut and pancreatic hormones, bile acids, and fibroblast growth factor-21 differ to glucose, protein, and fat ingestion after gastric bypass surgery. American journal of physiology. Gastrointestinal and liver physiology. vol 318. issue 4. 2020-07-24. PMID:32068442. |
secondary outcomes included responses of peptide yy (pyy), glucose-dependent insulinotropic polypeptide (gip), cholecystokinin (cck), glicentin, neurotensin, ghrelin, insulin, glucagon, bile acids, and fgf-21. |
2020-07-24 |
2023-08-13 |
human |
| Manabu Hoizumi, Takehiro Sato, Tatsunori Shimizu, Shunsuke Kato, Katsushi Tsukiyama, Takuma Narita, Hiroki Fujita, Tsukasa Morii, Mariko Harada Sassa, Yutaka Seino, Yuichiro Yamad. Inhibition of GIP signaling extends lifespan without caloric restriction. Biochemical and biophysical research communications. vol 513. issue 4. 2020-07-10. PMID:31003779. |
gip promotes glucose-dependent augmentation of insulin secretion and uptake of nutrients into the adipose tissue. |
2020-07-10 |
2023-08-13 |
Not clear |
| William G Tharp, Dhananjay Gupta, Olga Sideleva, Carolyn F Deacon, Jens J Holst, Dariush Elahi, Richard E Pratle. Effects of Pioglitazone on Glucose-Dependent Insulinotropic Polypeptide-Mediated Insulin Secretion and Adipocyte Receptor Expression in Patients With Type 2 Diabetes. Diabetes. vol 69. issue 2. 2020-07-02. PMID:31757794. |
insulin sensitivity improved, but the insulinotropic effect of infused gip was unchanged following 12 weeks of pioglitazone treatment. |
2020-07-02 |
2023-08-13 |
human |
| Vincent Mark. The early history of GIP 1969-2000: From enterogastrone to major metabolic hormone. Peptides. vol 122. 2020-06-29. PMID:31539554. |
augmentation of glucose mediated insulin release, the incretin effect, was discovered soon after gip was first isolated and only much later was its important role in the pathogenesis of obesity, through mechanism other than insulin secretion, appreciated. |
2020-06-29 |
2023-08-13 |
human |
| Jacqueline L Beaudry, Kiran D Kaur, Elodie M Varin, Laurie L Baggio, Xiemin Cao, Erin E Mulvihill, Holly E Bates, Jonathan E Campbell, Daniel J Drucke. Physiological roles of the GIP receptor in murine brown adipose tissue. Molecular metabolism. vol 28. 2020-06-22. PMID:31451430. |
glucose-dependent insulinotropic polypeptide (gip) is secreted from the gut in response to nutrient ingestion and promotes meal-dependent insulin secretion and lipid metabolism. |
2020-06-22 |
2023-08-13 |
Not clear |
| Jaber Alyami, Ella Whitehouse, Gleb E Yakubov, Susan E Pritchard, Caroline L Hoad, Elaine Blackshaw, Khaled Heissam, Sally M Cordon, H Frances J Bligh, Robin C Spiller, Ian A Macdonald, Guruprasad P Aithal, Penny A Gowland, Moira A Taylor, Luca Marcian. Glycaemic, gastrointestinal, hormonal and appetitive responses to pearl millet or oats porridge breakfasts: a randomised, crossover trial in healthy humans. The British journal of nutrition. vol 122. issue 10. 2020-06-04. PMID:31709970. |
blood samples for glucose, insulin, glucagon-like peptide 1, glucose-dependent insulinotropic polypeptide (gip), peptide yy, gastric volumes and appetite ratings were collected 2 h postprandially, followed by an ad libitum meal and food intake records for the remainder of the day. |
2020-06-04 |
2023-08-13 |
human |
| Chelsea R Hutch, Karen Roelofs, April Haller, Joyce Sorrell, Kyle Leix, David D D'Alessio, Robert Augustin, Randy J Seeley, Thomas Klein, Darleen A Sandova. The role of GIP and pancreatic GLP-1 in the glucoregulatory effect of DPP-4 inhibition in mice. Diabetologia. vol 62. issue 10. 2020-06-01. PMID:31414143. |
glucagon-like peptide-1 (glp-1) and glucose-dependent insulinotropic polypeptide (gip) are two peptides that function to promote insulin secretion. |
2020-06-01 |
2023-08-13 |
mouse |
| S L Craig, V A Gault, S McClean, G Hamscher, N Irwi. Effects of an enzymatically stable C-terminal hexapseudopeptide fragment peptide of xenin-25, ψ-xenin-6, on pancreatic islet function and metabolism. Molecular and cellular endocrinology. vol 496. 2020-05-28. PMID:31352038. |
in brin-bd11 cells and isolated murine islets, Ψ-xenin-6 significantly stimulated insulin secretion, and prominently enhanced the insulinotropic actions of gip. |
2020-05-28 |
2023-08-13 |
mouse |
| Qinchuan Wang, Huakang Tu, Meiling Zhu, Dong Liang, Yuanqing Ye, David W Chang, Yin Long, Xifeng W. Circulating obesity-driven biomarkers are associated with risk of clear cell renal cell carcinoma: a two-stage, case-control study. Carcinogenesis. vol 40. issue 10. 2020-05-27. PMID:31001636. |
obesity-driven biomarkers [gastric inhibitory polypeptide (gip), c-peptide, insulin, resistin, adipsin, peptide yy, pancreatic polypeptide, interleukin-6 (il-6), tumor necrosis factor-α (tnf-α), plasminogen activator inhibitor-1, monocyte chemoattractant protein 1, lipocalin2, leptin, adiponectin] were measured using the milliplex method. |
2020-05-27 |
2023-08-13 |
Not clear |
| Yanyan Liu, Shin-Ichi Harashima, Yu Wang, Kazuyo Suzuki, Shinsuke Tokumoto, Ryota Usui, Hisato Tatsuoka, Daisuke Tanaka, Daisuke Yabe, Norio Harada, Yoshitaka Hayashi, Nobuya Inagak. Sphingosine kinase 1-interacting protein is a dual regulator of insulin and incretin secretion. FASEB journal : official publication of the Federation of American Societies for Experimental Biology. vol 33. issue 5. 2020-05-18. PMID:30789757. |
we find here that skip is also expressed in intestinal k- and l-cells and that secretion of gastric inhibitory polypeptide (gip) and glucagon-like peptide-1 (glp-1) as well as insulin are significantly increased, and blood glucose levels are decreased in skip-deficient (skip |
2020-05-18 |
2023-08-13 |
Not clear |
| Daniel E Newmire, Eric Rivas, Sarah E Deemer, Darryn S Willoughby, Victor Ben-Ezr. The Impact of a Large Bolus Dose of l-leucine and l-isoleucine on Enteroendocrine and Pancreatic Hormones, and Glycemia in Healthy, Inactive Adults. Nutrients. vol 11. issue 11. 2020-05-08. PMID:31689951. |
the ingestion of whey protein and amino acids with carbohydrate (cho) enhances the release of glucagon-like peptide-1 (glp-1) and glucose-dependent-insulinotropic peptide (gip) that promote insulin secretion. |
2020-05-08 |
2023-08-13 |
Not clear |
| A Hasib, D Khan, S L Craig, V A Gault, P R Flatt, N Irwi. Antidiabetic effects and sustained metabolic benefits of sub-chronic co-administration of exendin-4/gastrin and xenin-8-Gln in high fat fed mice. European journal of pharmacology. vol 865. 2020-04-22. PMID:31614140. |
each treatment improved glucose tolerance and the glucose-lowering actions of glucose dependent insulinotropic polypeptide (gip), as well as augmenting glucose- and gip-induced insulin secretion, with benefits being most prominent in the combination group. |
2020-04-22 |
2023-08-13 |
mouse |
| Akiko Sankoda, Norio Harada, Tomoko Kato, Eri Ikeguchi, Kanako Iwasaki, Shunsuke Yamane, Yuki Murata, Akira Hirasawa, Nobuya Inagak. Free fatty acid receptors, G protein-coupled receptor 120 and G protein-coupled receptor 40, are essential for oil-induced gastric inhibitory polypeptide secretion. Journal of diabetes investigation. vol 10. issue 6. 2020-04-13. PMID:31002464. |
incretin hormone glucose-dependent insulinotropic polypeptide/gastric inhibitory polypeptide (gip) plays a key role in high-fat diet-induced obesity and insulin resistance. |
2020-04-13 |
2023-08-13 |
mouse |
| Simon F Jacobi, Noushafarin Khajavi, Gunnar Kleinau, Alexander Teumer, Patrick Scheerer, Georg Homuth, Henry Völzke, Susanna Wiegand, Peter Kühnen, Heiko Krude, Maolian Gong, Klemens Raile, Heike Bieberman. Evaluation of a rare glucose-dependent insulinotropic polypeptide receptor variant in a patient with diabetes. Diabetes, obesity & metabolism. vol 21. issue 5. 2020-03-30. PMID:30784161. |
glucose-dependent insulinotropic polypeptide (gip) is an incretin hormone that augments insulin secretion in pancreatic β-cells via its glucose-dependent insulinotropic polypeptide receptor (gipr). |
2020-03-30 |
2023-08-13 |
Not clear |
| E Miqueo, A Chiarle, M J Giuliodori, A E Rellin. Association between prepartum metabolic status and resumption of postpartum ovulation in dairy cows. Domestic animal endocrinology. vol 69. 2020-03-11. PMID:31301559. |
in this context, there is an increase in plasma nefa and ghrelin concentrations and a decrease in plasma insulin and glucose-dependent insulinotropic polypeptide (gip) concentrations. |
2020-03-11 |
2023-08-13 |
Not clear |
| E Miqueo, A Chiarle, M J Giuliodori, A E Rellin. Association between prepartum metabolic status and resumption of postpartum ovulation in dairy cows. Domestic animal endocrinology. vol 69. 2020-03-11. PMID:31301559. |
thus, the objective of the present study was to evaluate the association between plasma nefa concentration and metabolic hormones (insulin, ghrelin, and gip) before parturition and their associations with the resumption of postpartum ovulations in dairy cows. |
2020-03-11 |
2023-08-13 |
Not clear |
| E Miqueo, A Chiarle, M J Giuliodori, A E Rellin. Association between prepartum metabolic status and resumption of postpartum ovulation in dairy cows. Domestic animal endocrinology. vol 69. 2020-03-11. PMID:31301559. |
plasma nefa concentration (h-nefa mean = 294 μm, sd = 141.2; and l-nefa mean = 122 μm, sd = 25.3) was correlated (p < 0.01) with plasma insulin (r = -0.374) and ghrelin (r = -0.346) concentrations but not with plasma gip concentration (p = 0.64). |
2020-03-11 |
2023-08-13 |
Not clear |