| Publication |
Sentence |
Publish Date |
Extraction Date |
Species |
| Yoshinori Kanemaru, Norio Harada, Satoko Shimazu-Kuwahara, Shunsuke Yamane, Eri Ikeguchi, Yuki Murata, Sakura Kiyobayashi, Tomonobu Hatoko, Nobuya Inagak. Absence of GIP secretion alleviates age-related obesity and insulin resistance. The Journal of endocrinology. vol 245. issue 1. 2020-10-19. PMID:31977316. |
absence of gip secretion alleviates age-related obesity and insulin resistance. |
2020-10-19 |
2023-08-13 |
mouse |
| Yoshinori Kanemaru, Norio Harada, Satoko Shimazu-Kuwahara, Shunsuke Yamane, Eri Ikeguchi, Yuki Murata, Sakura Kiyobayashi, Tomonobu Hatoko, Nobuya Inagak. Absence of GIP secretion alleviates age-related obesity and insulin resistance. The Journal of endocrinology. vol 245. issue 1. 2020-10-19. PMID:31977316. |
fat strongly induces gip secretion, and gip hypersecretion is involved in high-fat diet-induced obesity and insulin resistance. |
2020-10-19 |
2023-08-13 |
mouse |
| Yoshinori Kanemaru, Norio Harada, Satoko Shimazu-Kuwahara, Shunsuke Yamane, Eri Ikeguchi, Yuki Murata, Sakura Kiyobayashi, Tomonobu Hatoko, Nobuya Inagak. Absence of GIP secretion alleviates age-related obesity and insulin resistance. The Journal of endocrinology. vol 245. issue 1. 2020-10-19. PMID:31977316. |
aging also induces gip hypersecretion, but its effect on body weight gain and insulin sensitivity remains unclear. |
2020-10-19 |
2023-08-13 |
mouse |
| Yoshinori Kanemaru, Norio Harada, Satoko Shimazu-Kuwahara, Shunsuke Yamane, Eri Ikeguchi, Yuki Murata, Sakura Kiyobayashi, Tomonobu Hatoko, Nobuya Inagak. Absence of GIP secretion alleviates age-related obesity and insulin resistance. The Journal of endocrinology. vol 245. issue 1. 2020-10-19. PMID:31977316. |
in the present study, we investigated the effect of gip on age-related body weight gain and insulin resistance using gip-knockout homozygous (gip-/-) and heterozygous (gip+/-) mice, which have entirely absent and 50% reduced gip secretion compared to wild-type (wt) mice, respectively. |
2020-10-19 |
2023-08-13 |
mouse |
| Yoshinori Kanemaru, Norio Harada, Satoko Shimazu-Kuwahara, Shunsuke Yamane, Eri Ikeguchi, Yuki Murata, Sakura Kiyobayashi, Tomonobu Hatoko, Nobuya Inagak. Absence of GIP secretion alleviates age-related obesity and insulin resistance. The Journal of endocrinology. vol 245. issue 1. 2020-10-19. PMID:31977316. |
these results demonstrate that gip is involved in age-related obesity and insulin resistance and that inhibition of gip secretion alleviates age-related fat mass gain and insulin resistance under carbohydrate-based diet feeding condition. |
2020-10-19 |
2023-08-13 |
mouse |
| Fahima Mayer, Amanda L Gunawan, Patrick Tso, Gregory W Apont. Glucagon-like peptide 1 and glucose-dependent insulinotropic polypeptide stimulate release of substance P from TRPV1- and TRPA1-expressing sensory nerves. American journal of physiology. Gastrointestinal and liver physiology. vol 319. issue 1. 2020-10-16. PMID:32421358. |
glucagon-like peptide-1 (glp-1) and glucose-dependent insulinotropic polypeptide (gip) are released from enteroendocrine cells (eecs) in response to nutrient ingestion and lower blood glucose levels by stimulation of insulin secretion and thus are defined as incretins. |
2020-10-16 |
2023-08-13 |
Not clear |
| Chia Lin Chang, Shang Yu Huang, Ya Chiung Hsu, Tzu Hsuan Chin, Yung Kuei Soon. The serum level of irisin, but not asprosin, is abnormal in polycystic ovary syndrome patients. Scientific reports. vol 9. issue 1. 2020-10-06. PMID:31015585. |
accordingly, we investigated serum levels of asprosin, irisin, gip, androgens, lh, glucose, insulin, and lipids as well as homa-ir, quicki and isi |
2020-10-06 |
2023-08-13 |
Not clear |
| Shingo Kainuma, Haruhiko Tokuda, Kazuhiko Fujita, Tetsu Kawabata, Go Sakai, Rie Matsushima-Nishiwaki, Atsushi Harada, Osamu Kozawa, Takanobu Otsuk. Attenuation by incretins of thyroid hormone-stimulated osteocalcin synthesis in osteoblasts. Biomedical reports. vol 5. issue 6. 2020-10-01. PMID:28105345. |
incretins, the polypeptide hormone glucose- dependent insulinotropic polypeptide (gip) and glucagon-like peptide-1 (glp-1) secreted from the small intestine after nutrient ingestion, are generally known to stimulate insulin secretion from pancreatic β-cells. |
2020-10-01 |
2023-08-13 |
Not clear |
| Gaurav Garg, Fiona E McGuigan, Jitender Kumar, Holger Luthman, Valeriya Lyssenko, Kristina Akesso. Glucose-dependent insulinotropic polypeptide ( Bone reports. vol 4. 2020-10-01. PMID:28326339. |
glucose-dependent insulinotropic polypeptide ( the gastro-intestinal hormone glucose-dependent insulinotropic polypeptide (gip) potentiates glucose-induced insulin secretion, with bone anabolic effects through gip receptor (gipr) in animal models. |
2020-10-01 |
2023-08-13 |
Not clear |
| Ghaith Al-Badri, Gian Marco Leggio, Giuseppe Musumeci, Rubina Marzagalli, Filippo Drago, Alessandro Castorin. Tackling dipeptidyl peptidase IV in neurological disorders. Neural regeneration research. vol 13. issue 1. 2020-10-01. PMID:29451201. |
dipeptidyl peptidase iv (dpp-iv) is a serine protease best known for its role in inactivating glucagon-like peptide-1 (glp-1), pituitary adenylate cyclase-activating polypeptide (pacap) and glucose-dependent insulinotropic peptide (gip), three stimulators of pancreatic insulin secretion with beneficial effects on glucose disposal. |
2020-10-01 |
2023-08-13 |
Not clear |
| Kirk A Abraham, Monica L Kearney, Leryn J Reynolds, John P Thyfaul. Red wine enhances glucose-dependent insulinotropic peptide (GIP) and insulin responses in type 2 diabetes during an oral glucose tolerance test. Diabetology international. vol 7. issue 2. 2020-10-01. PMID:30603261. |
red wine enhances glucose-dependent insulinotropic peptide (gip) and insulin responses in type 2 diabetes during an oral glucose tolerance test. |
2020-10-01 |
2023-08-13 |
Not clear |
| Kirk A Abraham, Monica L Kearney, Leryn J Reynolds, John P Thyfaul. Red wine enhances glucose-dependent insulinotropic peptide (GIP) and insulin responses in type 2 diabetes during an oral glucose tolerance test. Diabetology international. vol 7. issue 2. 2020-10-01. PMID:30603261. |
the purposes of this study were to evaluate the potential involvement of glucose-dependent insulinotropic peptide (gip) and glucagon-like peptide 1 (glp-1) in alcohol-induced augmentation of the insulin response and to determine if red wine acutely improves glucose tolerance during an oral glucose tolerance test (ogtt). |
2020-10-01 |
2023-08-13 |
Not clear |
| Jixin Zhong, Andrei Maiseyeu, Sanjay Rajagopala. Lipoprotein effects of incretin analogs and dipeptidyl peptidase 4 inhibitors. Clinical lipidology. vol 10. issue 1. 2020-09-30. PMID:26005496. |
the incretins glucagon like peptide-1 (glp-1) and glucose insulinotropic peptide (gip) modulate post-prandial lipoproteins through a multitude of pathways that are independent of insulin and weight loss. |
2020-09-30 |
2023-08-13 |
human |
| Yayoi Hosoda, Fumiaki Okahara, Takuya Mori, Jun Deguchi, Noriyasu Ota, Noriko Osaki, Akira Shimotoyodom. Dietary steamed wheat bran increases postprandial fat oxidation in association with a reduced blood glucose-dependent insulinotropic polypeptide response in mice. Food & nutrition research. vol 61. issue 1. 2020-09-30. PMID:28970776. |
energy metabolism was evaluated using an indirect calorimeter, and plasma glucose, insulin, and glucose-dependent insulinotropic polypeptide (gip) levels were measured for 120 min after feeding. |
2020-09-30 |
2023-08-13 |
mouse |
| Danielle T Vannan, Marc R Bomhof, Raylene A Reime. Comparison of Glucose and Satiety Hormone Response to Oral Glucose vs. Two Mixed-Nutrient Meals in Rats. Frontiers in nutrition. vol 5. 2020-09-30. PMID:30320120. |
blood was collected via tail snip and analyzed for glucose, insulin, glp-1, gip, pyy, amylin, leptin, and ghrelin. |
2020-09-30 |
2023-08-13 |
rat |
| Alyce M Martin, Emily W Sun, Geraint B Rogers, Damien J Keatin. The Influence of the Gut Microbiome on Host Metabolism Through the Regulation of Gut Hormone Release. Frontiers in physiology. vol 10. 2020-09-30. PMID:31057420. |
enteroendocrine cells within the mucosal lining of the gut synthesize and secrete a number of hormones including cck, pyy, glp-1, gip, and 5-ht, which have regulatory roles in key metabolic processes such as insulin sensitivity, glucose tolerance, fat storage, and appetite. |
2020-09-30 |
2023-08-13 |
human |
| Christian Hölsche. Insulin Signaling Impairment in the Brain as a Risk Factor in Alzheimer's Disease. Frontiers in aging neuroscience. vol 11. 2020-09-30. PMID:31068799. |
treatments to re-sensitize insulin signaling in the brain are also described, such as nasal insulin tests in ad patients, or treatments with re-sensitizing hormones, such as leptin, ghrelin, glucagon-like peptide 1 (glp-1),and glucose-dependent insulinotropic polypeptide (gip). |
2020-09-30 |
2023-08-13 |
Not clear |
| Xiaohui Feng, Haili Liu, Zhaoping Li, Arianna Carughi, Sheng G. Acute Effect of Pistachio Intake on Postprandial Glycemic and Gut Hormone Responses in Women With Gestational Diabetes or Gestational Impaired Glucose Tolerance: A Randomized, Controlled, Crossover Study. Frontiers in nutrition. vol 6. 2020-09-30. PMID:31921879. |
in summary, isocaloric pistachio intake induced significantly lower postprandial glucose, insulin and gip but higher glp-1 levels compared to wwb. |
2020-09-30 |
2023-08-13 |
Not clear |
| Rakesh C Chandarana, Vikrant, Ashok K Varma, Anil Saran, Evans C Coutinho, Jacinta S D'Souz. Over-expression, purification and isotopic labeling of a tag-less human glucose-dependent insulinotropic polypeptide (hGIP). 3 Biotech. vol 4. issue 5. 2020-09-29. PMID:28324382. |
glucose-dependent insulinotropic polypeptide (gip), a gut peptide released in response to food intake brings about secretion of insulin in a glucose-dependent manner upon binding to its receptor, gipr. |
2020-09-29 |
2023-08-13 |
human |
| Miaad Bader, Yazhou Li, David Tweedie, Nathan A Shlobin, Adi Bernstein, Vardit Rubovitch, Luis B Tovar-Y-Romo, Richard D DiMarchi, Barry J Hoffer, Nigel H Greig, Chaim G Pic. Neuroprotective Effects and Treatment Potential of Incretin Mimetics in a Murine Model of Mild Traumatic Brain Injury. Frontiers in cell and developmental biology. vol 7. 2020-09-29. PMID:31998717. |
the incretins glucagon-like peptide-1 (glp-1) and glucose-dependent insulinotropic polypeptide (gip) are gastrointestinal hormones that induce glucose-dependent insulin secretion, promote β-cell proliferation, and enhance resistance to apoptosis. |
2020-09-29 |
2023-08-13 |
mouse |