| Publication |
Sentence |
Publish Date |
Extraction Date |
Species |
| Oge Arum, Jamal K Saleh, Ravneet K Boparai, John J Kopchick, Romesh K Khardori, Andrzej Bartk. Preservation of blood glucose homeostasis in slow-senescing somatotrophism-deficient mice subjected to intermittent fasting begun at middle or old age. Age (Dordrecht, Netherlands). vol 36. issue 3. 2015-07-15. PMID:24789008. |
we find that either of the two genetic alterations in gh signaling ameliorates fasting hyperglycemia; additionally, both longevity-inducing somatotrophic mutations improve insulin sensitivity into old age. |
2015-07-15 |
2023-08-13 |
mouse |
| Miroslav Balaž, Barbara Ukropcova, Timea Kurdiova, Miroslav Vlcek, Martina Surova, Patrik Krumpolec, Peter Vanuga, Daniela Gašperíková, Iwar Klimeš, Juraj Payer, Christian Wolfrum, Jozef Ukrope. Improved adipose tissue metabolism after 5-year growth hormone replacement therapy in growth hormone deficient adults: The role of zinc-α2-glycoprotein. Adipocyte. vol 4. issue 2. 2015-07-13. PMID:26167410. |
growth hormone (gh) supplementation therapy to adults with gh deficiency has beneficial effects on adipose tissue lipid metabolism, improving thus adipocyte functional morphology and insulin sensitivity. |
2015-07-13 |
2023-08-13 |
human |
| Miroslav Balaž, Barbara Ukropcova, Timea Kurdiova, Miroslav Vlcek, Martina Surova, Patrik Krumpolec, Peter Vanuga, Daniela Gašperíková, Iwar Klimeš, Juraj Payer, Christian Wolfrum, Jozef Ukrope. Improved adipose tissue metabolism after 5-year growth hormone replacement therapy in growth hormone deficient adults: The role of zinc-α2-glycoprotein. Adipocyte. vol 4. issue 2. 2015-07-13. PMID:26167410. |
five-year gh replacement therapy improved glucose tolerance, adipose tissue insulin sensitivity and reduced adipocyte size without affecting adiposity and whole-body insulin sensitivity. |
2015-07-13 |
2023-08-13 |
human |
| Miroslav Balaž, Barbara Ukropcova, Timea Kurdiova, Miroslav Vlcek, Martina Surova, Patrik Krumpolec, Peter Vanuga, Daniela Gašperíková, Iwar Klimeš, Juraj Payer, Christian Wolfrum, Jozef Ukrope. Improved adipose tissue metabolism after 5-year growth hormone replacement therapy in growth hormone deficient adults: The role of zinc-α2-glycoprotein. Adipocyte. vol 4. issue 2. 2015-07-13. PMID:26167410. |
moreover, gh treatment improved antilipolytic action of insulin in cultured adipocytes. |
2015-07-13 |
2023-08-13 |
human |
| Miroslav Balaž, Barbara Ukropcova, Timea Kurdiova, Miroslav Vlcek, Martina Surova, Patrik Krumpolec, Peter Vanuga, Daniela Gašperíková, Iwar Klimeš, Juraj Payer, Christian Wolfrum, Jozef Ukrope. Improved adipose tissue metabolism after 5-year growth hormone replacement therapy in growth hormone deficient adults: The role of zinc-α2-glycoprotein. Adipocyte. vol 4. issue 2. 2015-07-13. PMID:26167410. |
effects of 5-year gh supplementation therapy on adipose tissue lipid metabolism and insulin sensitivity are associated with zinc-α2-glycoprotein. |
2015-07-13 |
2023-08-13 |
human |
| Daniela A Rubin, Diobel M Castner, Hoang Pham, Jason Ng, Eric Adams, Daniel A Judelso. Hormonal and metabolic responses to a resistance exercise protocol in lean children, obese children and lean adults. Pediatric exercise science. vol 26. issue 4. 2015-07-10. PMID:25372379. |
obesity in childhood negatively influenced gh, insulin, and glucose concentrations. |
2015-07-10 |
2023-08-13 |
human |
| Eva Baquedano, Ana M Ruiz-Lopez, Elahu G Sustarsic, James Herpy, Edward O List, Julie A Chowen, Laura M Frago, John J Kopchick, Jesús Argent. The absence of GH signaling affects the susceptibility to high-fat diet-induced hypothalamic inflammation in male mice. Endocrinology. vol 155. issue 12. 2015-07-08. PMID:25237935. |
gh is important in metabolic control, and mice with disruption of the gene encoding the gh receptor (ghr) and gh binding protein (ghr-/- mice) are dwarf with low serum igf-1 and insulin levels, high gh levels, and increased longevity, despite their obesity and altered lipid and metabolic profiles. |
2015-07-08 |
2023-08-13 |
mouse |
| Corina Galesanu, C Buzduga, A Florescu, Liliana Moisii, V Ciubotar. Diabetes mellitus, chronic complication in patients with acromegaly: case report and review of the literature. Revista medico-chirurgicala a Societatii de Medici si Naturalisti din Iasi. vol 119. issue 1. 2015-06-17. PMID:25970949. |
excess amounts of gh and igf1 interacts with metabolic regulation, and indeed, gh hypersecretion is associated with hepatic and peripheral insulin resistance; this and also other mechanisms are involved in the development of diabetes mellitus. |
2015-06-17 |
2023-08-13 |
Not clear |
| T Yada, B Damdindorj, R S Rita, T Kurashina, A Ando, M Taguchi, M Koizumi, H Sone, M Nakata, M Kakei, K Dezak. Ghrelin signalling in β-cells regulates insulin secretion and blood glucose. Diabetes, obesity & metabolism. vol 16 Suppl 1. 2015-06-01. PMID:25200304. |
ghrelin, initially identified as a potent stimulator of gh release and feeding, has been shown to suppress glucose-induced insulin release. |
2015-06-01 |
2023-08-13 |
mouse |
| Rikke Beck Jensen, Ajay Thankamony, Felix Day, Robert A Scott, Claudia Langenberg, Jeremy Kirk, Malcolm Donaldson, Sten-A Ivarsson, Olle Söder, Edna Roche, Hilary Hoey, Anders Juul, Ken K Ong, David B Dunge. Genetic markers of insulin sensitivity and insulin secretion are associated with spontaneous postnatal growth and response to growth hormone treatment in short SGA children: the North European SGA Study (NESGAS). The Journal of clinical endocrinology and metabolism. vol 100. issue 3. 2015-05-12. PMID:25494864. |
the wide heterogeneity in the early growth and metabolism of children born small for gestational age (sga), both before and during gh therapy, may reflect common genetic variations related to insulin secretion or sensitivity. |
2015-05-12 |
2023-08-13 |
Not clear |
| Anna Petryk, Roopa Kanakatti Shankar, Neelam Giri, Anthony N Hollenberg, Meilan M Rutter, Brandon Nathan, Maya Lodish, Blanche P Alter, Constantine A Stratakis, Susan R Ros. Endocrine disorders in Fanconi anemia: recommendations for screening and treatment. The Journal of clinical endocrinology and metabolism. vol 100. issue 3. 2015-05-12. PMID:25575015. |
about 80% of children and adults with fa have at least one endocrine abnormality, including short stature, gh deficiency, abnormal glucose or insulin metabolism, dyslipidemia, hypothyroidism, pubertal delay, hypogonadism, or impaired fertility. |
2015-05-12 |
2023-08-13 |
Not clear |
| Anju Virman. Growth disorders in type 1 diabetes: an Indian experience. Indian journal of endocrinology and metabolism. vol 19. issue Suppl 1. 2015-05-05. PMID:25941656. |
insulin regulates expression of hepatic gh receptors, affects igfs and igfbps synthesis by modulating gh postreceptor events, and significantly increases igf-i bioactivity. |
2015-05-05 |
2023-08-13 |
Not clear |
| Anju Virman. Growth disorders in type 1 diabetes: an Indian experience. Indian journal of endocrinology and metabolism. vol 19. issue Suppl 1. 2015-05-05. PMID:25941656. |
low portal insulin seen in t1dm leads to gh hypersecretion, low circulating igf-i and igfbp-3, and high circulating igfbp-1. |
2015-05-05 |
2023-08-13 |
Not clear |
| Noorisaem Rhee, Ka Young Oh, Eun Mi Yang, Chan Jong Ki. Growth hormone responses to provocative tests in children with short stature. Chonnam medical journal. vol 51. issue 1. 2015-04-27. PMID:25914878. |
subjects underwent gh provocation tests with insulin and l-dopa. |
2015-04-27 |
2023-08-13 |
human |
| Noorisaem Rhee, Ka Young Oh, Eun Mi Yang, Chan Jong Ki. Growth hormone responses to provocative tests in children with short stature. Chonnam medical journal. vol 51. issue 1. 2015-04-27. PMID:25914878. |
peak gh levels were achieved an average of 45 min after the administration of insulin and l-dopa for both groups. |
2015-04-27 |
2023-08-13 |
human |
| Noorisaem Rhee, Ka Young Oh, Eun Mi Yang, Chan Jong Ki. Growth hormone responses to provocative tests in children with short stature. Chonnam medical journal. vol 51. issue 1. 2015-04-27. PMID:25914878. |
in the iss group, the cumulative frequency of a gh cutoff value of >10 ng/ml at 120 min was 75.6% after insulin stimulation compared with 35.1% after l-dopa stimulation. |
2015-04-27 |
2023-08-13 |
human |
| Maureen J Charron, Patricia M Vugui. Lack of glucagon receptor signaling and its implications beyond glucose homeostasis. The Journal of endocrinology. vol 224. issue 3. 2015-04-21. PMID:25568163. |
glucagon action has been involved in the modulation of sweet taste responsiveness, inotropic and chronotropic effects in the heart, satiety, glomerular filtration rate, secretion of insulin, cortisol, ghrelin, gh, glucagon, and somatostatin, and hypothalamic signaling to suppress hepatic glucose production. |
2015-04-21 |
2023-08-13 |
mouse |
| S Wang, C Yu, C Sun, Z Li. [Changes and relations of leptin, growth hormone and insulin during puberty in obese and non-obese children]. Wei sheng yan jiu = Journal of hygiene research. vol 30. issue 4. 2015-04-11. PMID:12561520. |
in order to study the regularity of changing leptin, growth hormone (gh) and insulin (ins) during puberty and their relationships, a group of 300 obese and 300 non-obese children, aged 10-15 were selected. |
2015-04-11 |
2023-08-12 |
Not clear |
| Floryne O Buishand, Judith Visser, Marja Kik, Andrea Gröne, Rebekah I Keesler, Inge H Briaire-de Bruijn, Jolle Kirpensteij. Evaluation of prognostic indicators using validated canine insulinoma tissue microarrays. Veterinary journal (London, England : 1997). vol 201. issue 1. 2015-04-10. PMID:24878267. |
inter-observer agreement of tma immunohistochemistry scores were assessed for chromogranin a (cga), insulin, growth hormone (gh), growth hormone receptor (ghr) and ki67 index, as well as the prognostic utility of clinicopathological, histopathological and immunohistochemical criteria. |
2015-04-10 |
2023-08-13 |
Not clear |
| Tokushi Komatsu, Yumi Higashiyama, Michiru Fukasawa, Kazuo Katoh, Akinori Oshib. Physiological changes during feeding and rumination in cows. Animal science journal = Nihon chikusan Gakkaiho. vol 85. issue 3. 2015-04-06. PMID:24000947. |
during feeding and rumination, there were no characteristic increases and subsequent decreases in plasma insulin and growth hormone (gh) concentrations, although insulin concentrations were positively correlated with glucose concentration. |
2015-04-06 |
2023-08-12 |
cattle |