| Publication |
Sentence |
Publish Date |
Extraction Date |
Species |
| Christopher J Romero, Andrew Wolfe, Yi Ying Law, ChenChen Z Costelloe, Ryan Miller, Fredric Wondisford, Sally Radovic. Altered somatotroph feedback regulation improves metabolic efficiency and limits adipose deposition in male mice. Metabolism: clinical and experimental. vol 65. issue 4. 2016-07-25. PMID:26975547. |
furthermore, both gh and insulin growth factor 1 (igf-1) may also play a direct or indirect role in adipose development. |
2016-07-25 |
2023-08-13 |
mouse |
| Manouk van der Steen, Annemieke J Lem, Daniëlle C M van der Kaay, Anita C S Hokken-Koeleg. Insulin Sensitivity and β-Cell Function in SGA Children Treated With GH and GnRHa: Results of a Long-Term Trial. The Journal of clinical endocrinology and metabolism. vol 101. issue 2. 2016-06-29. PMID:26653111. |
insulin sensitivity and β-cell function in sga children treated with gh and gnrha: results of a long-term trial. |
2016-06-29 |
2023-08-13 |
Not clear |
| Manouk van der Steen, Annemieke J Lem, Daniëlle C M van der Kaay, Anita C S Hokken-Koeleg. Insulin Sensitivity and β-Cell Function in SGA Children Treated With GH and GnRHa: Results of a Long-Term Trial. The Journal of clinical endocrinology and metabolism. vol 101. issue 2. 2016-06-29. PMID:26653111. |
because both gh and gnrha can negatively influence insulin sensitivity, combining these treatments has raised concerns. |
2016-06-29 |
2023-08-13 |
Not clear |
| Manouk van der Steen, Annemieke J Lem, Daniëlle C M van der Kaay, Anita C S Hokken-Koeleg. Insulin Sensitivity and β-Cell Function in SGA Children Treated With GH and GnRHa: Results of a Long-Term Trial. The Journal of clinical endocrinology and metabolism. vol 101. issue 2. 2016-06-29. PMID:26653111. |
the long-term gh dose effects on insulin sensitivity in children treated with combined gh/gnrha are unknown. |
2016-06-29 |
2023-08-13 |
Not clear |
| Sana Doubi, Zoubida Amrani, Hanan El Ouahabi, Saïd Boujraf, Farida Ajd. Exceptional Association Between Klinefelter Syndrome and Growth Hormone Deficiency. Genome integrity. vol 6. 2016-06-22. PMID:27330737. |
gh deficiency was isolated and confirmed by two dynamic tests (insulin - hypoglycemia tolerance test and clonidine) with normal hypothalamic magnetic resonance imaging (mri). |
2016-06-22 |
2023-08-13 |
Not clear |
| Erin R Hascup, Feiya Wang, John J Kopchick, Andrzej Bartk. Inflammatory and Glutamatergic Homeostasis Are Involved in Successful Aging. The journals of gerontology. Series A, Biological sciences and medical sciences. vol 71. issue 3. 2016-06-14. PMID:25711529. |
whole body studies using long-lived growth hormone receptor gene disrupted or knock out (ghr-ko) mice report global gh resistance, increased insulin sensitivity, reduced insulin-like growth factor 1 (igf-1), and cognitive retention in old-age, however, little is known about the neurobiological status of these mice. |
2016-06-14 |
2023-08-13 |
mouse |
| P Harkitis, E P Daskalopoulos, F Malliou, M A Lang, M Marselos, A Fotopoulos, G Albucharali, M Konstand. Dopamine D2-Receptor Antagonists Down-Regulate CYP1A1/2 and CYP1B1 in the Rat Liver. PloS one. vol 10. issue 10. 2016-06-06. PMID:26466350. |
dopaminergic systems regulate the release of several hormones including growth hormone (gh), thyroid hormones, insulin, glucocorticoids and prolactin (prl) that play significant roles in the regulation of various cytochrome p450 (cyp) enzymes. |
2016-06-06 |
2023-08-13 |
rat |
| Carolina Di Somma, Alessandro Ciresi, Marco C Amato, Silvia Savastano, Maria Cristina Savanelli, Elisabetta Scarano, Annamaria Colao, Carla Giordan. Alteration of the growth hormone axis, visceral fat dysfunction, and early cardiometabolic risk in adults: the role of the visceral adiposity index. Endocrine. vol 49. issue 2. 2016-05-26. PMID:25381601. |
anthropometric measures, lipid profile, and glucose and insulin levels during oral glucose tolerance test, homa-ir and isi matsuda, igf-i and gh peak after ghrh plus arginine test were analyzed. |
2016-05-26 |
2023-08-13 |
human |
| Carolina Di Somma, Alessandro Ciresi, Marco C Amato, Silvia Savastano, Maria Cristina Savanelli, Elisabetta Scarano, Annamaria Colao, Carla Giordan. Alteration of the growth hormone axis, visceral fat dysfunction, and early cardiometabolic risk in adults: the role of the visceral adiposity index. Endocrine. vol 49. issue 2. 2016-05-26. PMID:25381601. |
the subjects with gh peak and igf-i unr under the cut-off showed significantly higher levels of vai, systolic and diastolic blood pressure, glucose and insulin levels, homa-ir, and lower isi matsuda, with a concomitant worse lipid profile (all p < 0.001). |
2016-05-26 |
2023-08-13 |
human |
| A Ciresi, M C Amato, C Giordan. Reduction in insulin sensitivity and inadequate β-cell capacity to counteract the increase in insulin resistance in children with idiopathic growth hormone deficiency during 12 months of growth hormone treatment. Journal of endocrinological investigation. vol 38. issue 3. 2016-05-24. PMID:25273336. |
to evaluate the performance of various indexes of insulin sensitivity and secretion and to identify the most useful indicator of deterioration of glucose metabolism in a cohort of children with growth hormone (gh) deficiency (ghd) during gh treatment. |
2016-05-24 |
2023-08-13 |
Not clear |
| Ronaldo D Piovezan, Julio Abucham, Ronaldo Vagner Thomatieli Dos Santos, Marco Tulio Mello, Sergio Tufik, Dalva Poyare. The impact of sleep on age-related sarcopenia: Possible connections and clinical implications. Ageing research reviews. vol 23. issue Pt B. 2016-05-23. PMID:26216211. |
several protein synthesis and degradation pathways are mediated by growth hormone (gh), insulin-like growth factor-1 (igf-1), testosterone, cortisol and insulin, which act on the cellular and molecular levels to increase or reestablish muscle fiber, strength and function. |
2016-05-23 |
2023-08-13 |
Not clear |
| Lisa Arnetz, Mozhgan Dorkhan, Michael Alvarsson, Kerstin Brismar, Neda Rajamand Ekber. Gender differences in non-glycemic responses to improved insulin sensitivity by pioglitazone treatment in patients with type 2 diabetes. Acta diabetologica. vol 51. issue 2. 2016-05-19. PMID:23389468. |
excess cortisol and gh induce insulin resistance, a central feature of type 2 diabetes (t2d). |
2016-05-19 |
2023-08-12 |
Not clear |
| Danika Krupp, Thomas Remer, Katharina J Penczynski, Katja Bolzenius, Stefan A Wudy, Anette E Buyke. Relevance of fruits, vegetables and flavonoids from fruits and vegetables during early life, mid-childhood and adolescence for levels of insulin-like growth factor (IGF-1) and its binding proteins IGFBP-2 and IGFBP-3 in young adulthood. The British journal of nutrition. vol 115. issue 3. 2016-05-18. PMID:26628272. |
the growth hormone (gh) insulin-like growth factor (igf) axis has been linked to insulin metabolism and cancer risk. |
2016-05-18 |
2023-08-13 |
human |
| Ajay Thankamony, Rikke Beck Jensen, Susan M O'Connell, Felix Day, Jeremy Kirk, Malcolm Donaldson, Sten A Ivarsson, Olle Söder, Edna Roche, Hilary Hoey, Ken K Ong, David B Dunger, Anders Juu. Adiposity in Children Born Small for Gestational Age Is Associated With β-Cell Function, Genetic Variants for Insulin Resistance, and Response to Growth Hormone Treatment. The Journal of clinical endocrinology and metabolism. vol 101. issue 1. 2016-05-09. PMID:26588449. |
insulin resistance, and therefore adiposity, may alter sensitivity to gh. |
2016-05-09 |
2023-08-13 |
Not clear |
| Ajay Thankamony, Rikke Beck Jensen, Susan M O'Connell, Felix Day, Jeremy Kirk, Malcolm Donaldson, Sten A Ivarsson, Olle Söder, Edna Roche, Hilary Hoey, Ken K Ong, David B Dunger, Anders Juu. Adiposity in Children Born Small for Gestational Age Is Associated With β-Cell Function, Genetic Variants for Insulin Resistance, and Response to Growth Hormone Treatment. The Journal of clinical endocrinology and metabolism. vol 101. issue 1. 2016-05-09. PMID:26588449. |
we aimed to determine the relationship between adiposity, genetic susceptibility to insulin resistance or insulin secretion, and response to gh treatment in short children born small for gestational age (sga). |
2016-05-09 |
2023-08-13 |
Not clear |
| A Valea, M Carsote, C Ghervan, C Georgesc. Glycemic profile in patients with acromegaly treated with somatostatin analogue. Journal of medicine and life. vol 8 Spec Issue. 2016-05-02. PMID:26361517. |
the growth hormone (gh) excess displayed in acromegaly induces insulin resistance up to diabetes mellitus (dm). |
2016-05-02 |
2023-08-13 |
Not clear |
| Jaime Guevara-Aguirre, Arlan L Rosenbloo. Obesity, diabetes and cancer: insight into the relationship from a cohort with growth hormone receptor deficiency. Diabetologia. vol 58. issue 1. 2016-04-12. PMID:25316432. |
in ecuador there are ~100 living adults with lifelong igf-1 deficiency caused by a gh receptor (ghr) mutation who, despite a high percentage of body fat, have markedly increased insulin sensitivity compared with age- and bmi-matched control relatives, and no instances of diabetes, which is present in 6% of unaffected relatives. |
2016-04-12 |
2023-08-13 |
Not clear |
| Jose Cordoba-Chacon, Neena Majumdar, Naveen K Pokala, Manuel D Gahete, Rhonda D Kinema. Islet insulin content and release are increased in male mice with elevated endogenous GH and IGF-I, without evidence of systemic insulin resistance or alterations in β-cell mass. Growth hormone & IGF research : official journal of the Growth Hormone Research Society and the International IGF Research Society. vol 25. issue 4. 2016-04-07. PMID:25936582. |
islet insulin content and release are increased in male mice with elevated endogenous gh and igf-i, without evidence of systemic insulin resistance or alterations in β-cell mass. |
2016-04-07 |
2023-08-13 |
mouse |
| Jose Cordoba-Chacon, Neena Majumdar, Naveen K Pokala, Manuel D Gahete, Rhonda D Kinema. Islet insulin content and release are increased in male mice with elevated endogenous GH and IGF-I, without evidence of systemic insulin resistance or alterations in β-cell mass. Growth hormone & IGF research : official journal of the Growth Hormone Research Society and the International IGF Research Society. vol 25. issue 4. 2016-04-07. PMID:25936582. |
it is clear that elevations in circulating gh can lead to an increase in insulin levels. |
2016-04-07 |
2023-08-13 |
mouse |
| Jose Cordoba-Chacon, Neena Majumdar, Naveen K Pokala, Manuel D Gahete, Rhonda D Kinema. Islet insulin content and release are increased in male mice with elevated endogenous GH and IGF-I, without evidence of systemic insulin resistance or alterations in β-cell mass. Growth hormone & IGF research : official journal of the Growth Hormone Research Society and the International IGF Research Society. vol 25. issue 4. 2016-04-07. PMID:25936582. |
however, there is also in vitro and in vivo evidence that gh acts directly to increase β-cell proliferation and insulin production. |
2016-04-07 |
2023-08-13 |
mouse |