| Publication |
Sentence |
Publish Date |
Extraction Date |
Species |
| Jose Cordoba-Chacon, Neena Majumdar, Naveen K Pokala, Manuel D Gahete, Rhonda D Kinema. Islet insulin content and release are increased in male mice with elevated endogenous GH and IGF-I, without evidence of systemic insulin resistance or alterations in β-cell mass. Growth hormone & IGF research : official journal of the Growth Hormone Research Society and the International IGF Research Society. vol 25. issue 4. 2016-04-07. PMID:25936582. |
this metabolic phenotype suggests that modest elevations in circulating gh and igf-i may enhance β-cell mass and/or function, in the absence of systemic insulin resistance, thus improving glucose homeostasis. |
2016-04-07 |
2023-08-13 |
mouse |
| N R Irani, K Venugopal, N Kontorinis, M Lee, R Sinniah, T R Bate. Glycogenic hepatopathy is an under-recognised cause of hepatomegaly and elevated liver transaminases in type 1 diabetes mellitus. Internal medicine journal. vol 45. issue 7. 2016-04-05. PMID:26134697. |
he was subsequently diagnosed with gh on liver biopsy, with the mainstay of treatment being reduction in caloric intake and insulin. |
2016-04-05 |
2023-08-13 |
Not clear |
| Klas Ekström, Mari-Anne Pulkkinen, Christine Carlsson-Skwirut, Anna-Lena Brorsson, Zhulin Ma, Jan Frystyk, Peter Ban. Tissue IGF-I Measured by Microdialysis Reflects Body Glucose Utilization After rhIGF-I Injection in Type 1 Diabetes. The Journal of clinical endocrinology and metabolism. vol 100. issue 11. 2016-02-17. PMID:26331550. |
type 1 diabetes is associated with portal insulin deficiency and disturbances in the gh-igf axis including low circulating igf-i and gh hypersecretion. |
2016-02-17 |
2023-08-13 |
Not clear |
| L Prokop, M Kaske, P Maccari, R Lucius, H-J Kunz, S Wiedeman. Intensive rearing of male calves during the first three weeks of life has long-term effects on number of islets of Langerhans and insulin stained area in the pancreas. Journal of animal science. vol 93. issue 3. 2016-02-12. PMID:26020877. |
plasma glucose, insulin, igf-1, and gh levels were assessed in wk 1, 2, 3, and 10 of life. |
2016-02-12 |
2023-08-13 |
Not clear |
| L Prokop, M Kaske, P Maccari, R Lucius, H-J Kunz, S Wiedeman. Intensive rearing of male calves during the first three weeks of life has long-term effects on number of islets of Langerhans and insulin stained area in the pancreas. Journal of animal science. vol 93. issue 3. 2016-02-12. PMID:26020877. |
intensive rearing led to increased plasma glucose, insulin, and igf-1 concentrations after 3 wk of life compared with rearing to the established standard protocol (all < 0.05), whereas gh was lower in int calves during the second week of life. |
2016-02-12 |
2023-08-13 |
Not clear |
| Andrew Do, Vinal Menon, Xu Zhi, Adam Gesing, Denise S Wiesenborn, Adam Spong, Liou Sun, Andrzej Bartke, Michal M Masterna. Thyroxine modifies the effects of growth hormone in Ames dwarf mice. Aging. vol 7. issue 4. 2016-02-02. PMID:25935838. |
treatment of juvenile df/df mice with gh alone stimulates somatic growth, reduces insulin sensitivity and shortens lifespan. |
2016-02-02 |
2023-08-13 |
mouse |
| Andrew Do, Vinal Menon, Xu Zhi, Adam Gesing, Denise S Wiesenborn, Adam Spong, Liou Sun, Andrzej Bartke, Michal M Masterna. Thyroxine modifies the effects of growth hormone in Ames dwarf mice. Aging. vol 7. issue 4. 2016-02-02. PMID:25935838. |
expression of genes related to gh and insulin signaling in the skeletal muscle and white adipose tissue (wat) of female dwarfs was differentially affected by treatment with gh + t4 vs. gh alone. |
2016-02-02 |
2023-08-13 |
mouse |
| Andrew Do, Vinal Menon, Xu Zhi, Adam Gesing, Denise S Wiesenborn, Adam Spong, Liou Sun, Andrzej Bartke, Michal M Masterna. Thyroxine modifies the effects of growth hormone in Ames dwarf mice. Aging. vol 7. issue 4. 2016-02-02. PMID:25935838. |
differences in the effects of gh + t4 vs. gh alone on insulin target tissues may contribute to the differential effects of these treatments on longevity. |
2016-02-02 |
2023-08-13 |
mouse |
| Marion Piechotta, Lars Holzhausen, Marcelo Gil Araujo, Maike Heppelmann, Anja Sipka, Chistiane Pfarrer, Hans-Joachim Schuberth, Heinrich Bollwei. Antepartal insulin-like growth factor concentrations indicating differences in the metabolic adaptive capacity of dairy cows. Journal of veterinary science. vol 15. issue 3. 2016-01-15. PMID:24962413. |
blood samples were drawn daily (day -17 until calving) and igf-i, gh, insulin, thyroid hormones, estradiol, and progesterone concentrations were measured. |
2016-01-15 |
2023-08-13 |
Not clear |
| F Y Obese, C MacCarthy, R Osei-Amponsah, R A Ayizanga, J K Dampte. Blood metabolite profiles in cycling and non-cycling Friesian-Sanga cross-bred cows grazing natural pasture during the post-partum period. Reproduction in domestic animals = Zuchthygiene. vol 50. issue 2. 2015-12-03. PMID:25683608. |
an experiment was conducted to investigate the effect of plasma concentrations of the metabolic hormones [growth hormone (gh), insulin and insulin-like growth factor -i (igf-i)] and nutritional metabolites (glucose, cholesterol, total protein, albumin, globulin, urea and creatinine) on the resumption of post-partum ovarian activity in sixteen friesian-sanga cows grazing extensively on native grassland. |
2015-12-03 |
2023-08-13 |
Not clear |
| F Y Obese, C MacCarthy, R Osei-Amponsah, R A Ayizanga, J K Dampte. Blood metabolite profiles in cycling and non-cycling Friesian-Sanga cross-bred cows grazing natural pasture during the post-partum period. Reproduction in domestic animals = Zuchthygiene. vol 50. issue 2. 2015-12-03. PMID:25683608. |
the concentrations of the metabolic hormones, gh and insulin were similar (p > 0.05) in the three ovarian activity groups, likewise the concentrations of the nutritional metabolites, glucose, total protein, globulin, urea and creatinine. |
2015-12-03 |
2023-08-13 |
Not clear |
| W Y So, Q Cheng, A Xu, K S L Lam, P S Leun. Loss of fibroblast growth factor 21 action induces insulin resistance, pancreatic islet hyperplasia and dysfunction in mice. Cell death & disease. vol 6. 2015-11-30. PMID:25811804. |
furthermore, distorted islet morphology and impaired gsis were observed in ko mice, suggestive of islet dysfunction, whereas the enhanced insulin expression and impaired gsis in fgf21-ko mouse islets could be reversed by blockade of gh signaling. |
2015-11-30 |
2023-08-13 |
mouse |
| W Y So, Q Cheng, A Xu, K S L Lam, P S Leun. Loss of fibroblast growth factor 21 action induces insulin resistance, pancreatic islet hyperplasia and dysfunction in mice. Cell death & disease. vol 6. 2015-11-30. PMID:25811804. |
our data indicate that fgf21 is important in the regulation of beta-cell proliferation and insulin synthesis, probably via modulation of gh signaling. |
2015-11-30 |
2023-08-13 |
mouse |
| L Cruz-Garcia, J Sánchez-Gurmaches, M Monroy, J Gutiérrez, I Navarr. Regulation of lipid metabolism and peroxisome proliferator-activated receptors in rainbow trout adipose tissue by lipolytic and antilipolytic endocrine factors. Domestic animal endocrinology. vol 51. 2015-11-24. PMID:25594950. |
cells were also incubated with gh, tumor necrosis factor α (tnfα), or insulin to analyze the gene expression of peroxisome proliferator-activated receptors (ppars) and lipid metabolism markers: hormone sensitive lipase, fatty acid synthase (fas), and lipoprotein lipase. |
2015-11-24 |
2023-08-13 |
Not clear |
| L Cruz-Garcia, J Sánchez-Gurmaches, M Monroy, J Gutiérrez, I Navarr. Regulation of lipid metabolism and peroxisome proliferator-activated receptors in rainbow trout adipose tissue by lipolytic and antilipolytic endocrine factors. Domestic animal endocrinology. vol 51. 2015-11-24. PMID:25594950. |
the anabolic action of insulin was demonstrated through its upregulation of lipogenic genes such as lipoprotein lipase, fas, and pparγ, whereas gh, by contrast, inhibited fas expression in adipose tissue. |
2015-11-24 |
2023-08-13 |
Not clear |
| N Dubey Nee Pathak, Pankaj Kumar, Bechan La. Endocrine regulation of testosterone production by Leydig cells in the catfish, Clarias batrachus: probable mediators of growth hormone. Animal reproduction science. vol 154. 2015-11-23. PMID:25650168. |
exogenous administration of gth, gh and insulin to the male catfish increased testicular and circulating testosterone level. |
2015-11-23 |
2023-08-13 |
Not clear |
| Carlos M Reyes-Vidal, Hamed Mojahed, Wei Shen, Zhezhen Jin, Fernando Arias-Mendoza, Jean Carlos Fernandez, Dympna Gallagher, Jeffrey N Bruce, Kalmon D Post, Pamela U Fred. Adipose Tissue Redistribution and Ectopic Lipid Deposition in Active Acromegaly and Effects of Surgical Treatment. The Journal of clinical endocrinology and metabolism. vol 100. issue 8. 2015-11-17. PMID:26037515. |
however, when in excess in acromegaly, the lipolytic and insulin antagonistic effects of gh may alter adipose tissue (at) deposition. |
2015-11-17 |
2023-08-13 |
Not clear |
| Zongyong Jiang, Shaoyong Wei, Zhilin Wang, Cui Zhu, Shenglan Hu, Chuntian Zheng, Zhuang Chen, Youjun Hu, Li Wang, Xianyong Ma, Xuefen Yan. Effects of different forms of yeast Saccharomyces cerevisiae on growth performance, intestinal development, and systemic immunity in early-weaned piglets. Journal of animal science and biotechnology. vol 6. 2015-11-16. PMID:26568826. |
serum concentrations of growth hormone (gh), triiodothyronine (t3), tetraiodothyronine (t4), and insulin growth factor 1 (igf-1) in piglets at day 21 of the experiment were higher when fed diets supplemented with ly and sfy than those in control group (p < 0.05). |
2015-11-16 |
2023-08-13 |
Not clear |
| Johannes D Veldhuis, Thomas P Olson, Paul Y Takahashi, John M Miles, Michael J Joyner, Rebecca J Yang, Jean Wigha. Multipathway modulation of exercise and glucose stress effects upon GH secretion in healthy men. Metabolism: clinical and experimental. vol 64. issue 9. 2015-11-09. PMID:26028283. |
here we test the hypothesis that age, sex steroids, insulin, body composition and physical power jointly determine these dynamic gh responses. |
2015-11-09 |
2023-08-13 |
Not clear |
| B Nellemann, M H Vendelbo, T S Nielsen, A M Bak, M Høgild, S B Pedersen, R S Biensø, H Pilegaard, N Møller, N Jessen, J O L Jørgense. Growth hormone-induced insulin resistance in human subjects involves reduced pyruvate dehydrogenase activity. Acta physiologica (Oxford, England). vol 210. issue 2. 2015-10-30. PMID:24148194. |
insulin resistance induced by growth hormone (gh) is linked to promotion of lipolysis by unknown mechanisms. |
2015-10-30 |
2023-08-12 |
human |