| Publication |
Sentence |
Publish Date |
Extraction Date |
Species |
| Huei Gau Chuang, NurNaznee Hirni Abd Aziz, Jia Hui Wong, Muzaimi Mustapha, Jafri Malin Abdullah, Zamzuri Idris, Zuraidah Abdullah, Aziza Alrafiah, Sangu Muthuraj. Role of toll-like receptor 4 antagonist Lipopolysaccharide-Rhodobacter sphaeroides on acute stress-induced voluntary ethanol preference and drinking behaviour: In vivo Swiss Albino mouse model. European neuropsychopharmacology : the journal of the European College of Neuropsychopharmacology. vol 45. 2021-11-22. PMID:32014377. |
morphological analysis showed no significant change in the prefrontal cortex and hippocampus among all groups, while immunoreactivity analysis showed higher expression of c-fos in prefrontal cortex and hippocampus, higher tlr4 expression in the prefrontal cortex and glial fibrillary acidic protein (gfap) in hippocampus among stressed-animals. |
2021-11-22 |
2023-08-13 |
mouse |
| Eman S Said, Asmaa M Elsayed, Laila A Rashed, Eman H Nadwa, Njood A Alsuhaibani, Batool S Alfuraih, Rania H Mahmou. Evaluation of nootropic activity of telmisartan and metformin on diazepam-induced cognitive dysfunction in mice through AMPK pathway and amelioration of hippocampal morphological alterations. European journal of pharmacology. vol 912. 2021-11-22. PMID:34547248. |
histological and immunohistochemical techniques were performed in hippocampus using h&e, cresyl violet stain, anti gfap and anti cox-2 immunostain. |
2021-11-22 |
2023-08-13 |
mouse |
| Eman S Said, Asmaa M Elsayed, Laila A Rashed, Eman H Nadwa, Njood A Alsuhaibani, Batool S Alfuraih, Rania H Mahmou. Evaluation of nootropic activity of telmisartan and metformin on diazepam-induced cognitive dysfunction in mice through AMPK pathway and amelioration of hippocampal morphological alterations. European journal of pharmacology. vol 912. 2021-11-22. PMID:34547248. |
also they decreased tnf-α, nfκb, and caspase 3 and upregulated ampk expression, moreover they ameliorated the hippocampal morphological alterations, gfap and cox-2 immunoexpression. |
2021-11-22 |
2023-08-13 |
mouse |
| Ilektra Anagnostou, Daniel Muñoz-Mayorga, Teresa Morale. Prolactin neuroprotective action against excitotoxic insult in the hippocampus of male mice. Peptides. vol 135. 2021-11-19. PMID:33053420. |
neurodegeneration (fluoro-jade c), neuronal survival (neun) and astrogliosis (gfap) markers were identified with immunohistochemistry in the ca1, ca3 and ca4 areas of the dorsal hippocampus, as well as prl-related protein levels by western blot in the whole hippocampus 48 h after excitotoxicity. |
2021-11-19 |
2023-08-13 |
mouse |
| Akram Tayanloo-Beik, Zahra Kiasalari, Mehrdad Roghan. Paeonol Ameliorates Cognitive Deficits in Streptozotocin Murine Model of Sporadic Alzheimer's Disease via Attenuation of Oxidative Stress, Inflammation, and Mitochondrial Dysfunction. Journal of molecular neuroscience : MN. 2021-11-19. PMID:34797511. |
paeonol treatment was also associated with lower hippocampal immunoreactivity for gfap. |
2021-11-19 |
2023-08-13 |
rat |
| Rebecca L Lowery, MaKenna Y Cealie, Cassandra E Lamantia, Monique S Mendes, Paul D Drew, Ania K Majewsk. Microglia and astrocytes show limited, acute alterations in morphology and protein expression following a single developmental alcohol exposure. Journal of neuroscience research. vol 99. issue 8. 2021-11-18. PMID:33606320. |
we found that although a single ethanol exposure delivered subcutaneously on postnatal day 4 did not cause large changes in microglial morphology or the expression of aldh1l1 and gfap in the cortex and hippocampus, subtle effects were observed. |
2021-11-18 |
2023-08-13 |
mouse |
| Guiping Wang, Huan-Huan Zhou, Lan Luo, Li-Qiang Qin, Jieyun Yin, Zengli Yu, Lin Zhang, Zhongxiao Wa. Voluntary wheel running is capable of improving cognitive function only in the young but not the middle-aged male APPSwe/PS1De9 mice. Neurochemistry international. vol 145. 2021-11-18. PMID:33684544. |
for the middle-aged app/ps1 mice, exercise reduced adam10 and gfap protein expression in hippocampus, with no notable alterations in circulating metabolites; additionally, mice from exercise group had markedly reduced abundance of the phyla proteobacteria and tenericutes, genera bacteroides and faecalibacterium, and elevated abundance of the genera allobaculum. |
2021-11-18 |
2023-08-13 |
mouse |
| Luis Enrique Arroyo-García, Hiram Tendilla-Beltrán, Rubén Antonio Vázquez-Roque, Erick Ernesto Jurado-Tapia, Alfonso Díaz, Patricia Aguilar-Alonso, Eduardo Brambila, Eduardo Monjaraz, Fidel De La Cruz, Antonio Rodríguez-Moreno, Gonzalo Flore. Amphetamine sensitization alters hippocampal neuronal morphology and memory and learning behaviors. Molecular psychiatry. vol 26. issue 9. 2021-11-15. PMID:32555421. |
after the nort, we performed golgi-cox staining, a stereological cell count, immunohistochemistry to determine the presence of gfap, casp3, and mt-iii, and evaluated oxidative stress in the hippocampus. |
2021-11-15 |
2023-08-13 |
Not clear |
| Mizuki Uchida, Yukihiro Noda, Sho Hasegawa, Hirotake Hida, Masayuki Taniguchi, Akihiro Mouri, Akira Yoshimi, Toshitaka Nabeshima, Kiyofumi Yamada, Tomomi Aida, Kohichi Tanaka, Norio Ozak. Early postnatal inhibition of GLAST causes abnormalities of psychobehaviors and neuronal morphology in adult mice. Neurochemistry international. vol 150. 2021-11-11. PMID:34481039. |
at 8 weeks of age, they showed impairments in cognitive or emotional behaviors; dysfunction of glutamatergic neurotransmission (increased expressions of glast, glt-1, or gfap protein, and decreased ability of glutamate release) in the cortex or hippocampus; morphological changes (decreased cell size in the cortex and thickness of the pyramidal neuronal layer of the ca1 area in the hippocampus). |
2021-11-11 |
2023-08-13 |
mouse |
| Heather Bondi, Valeria Bortolotto, Pier Luigi Canonico, Mariagrazia Grill. Complex and regional-specific changes in the morphological complexity of GFAP Neurobiology of aging. vol 100. 2021-11-08. PMID:33493951. |
complex and regional-specific changes in the morphological complexity of gfap during aging, alterations in astrocyte phenotype occur in areas associated with age-related cognitive decline, including hippocampus. |
2021-11-08 |
2023-08-13 |
Not clear |
| Shanshan Liu, Qing Liu, Yanjie Ju, Lei Li. Downregulation of miR-383 reduces depression-like behavior through targeting Wnt family member 2 (Wnt2) in rats. Scientific reports. vol 11. issue 1. 2021-11-08. PMID:33927285. |
downregulation of mir-383 significantly inhibited the apoptosis and inflammatory response of hippocampal neurons, and increased the expression levels of gfap, bdnf and creb which were impacted in depression, as well as neurotransmitters, then attenuated neural injury in rats induced by cums. |
2021-11-08 |
2023-08-13 |
rat |
| Iohanna Deckmann, Júlio Santos-Terra, Mellanie Fontes-Dutra, Marília Körbes-Rockenbach, Guilherme Bauer-Negrini, Gustavo Brum Schwingel, Rudimar Riesgo, Victorio Bambini-Junior, Carmem Gottfrie. Resveratrol prevents brain edema, blood-brain barrier permeability, and altered aquaporin profile in autism animal model. International journal of developmental neuroscience : the official journal of the International Society for Developmental Neuroscience. vol 81. issue 7. 2021-11-02. PMID:34196408. |
finally, there was an effect of resveratrol per se on the number of astrocytes and gfap fluorescence in the amygdala region and in the hippocampus. |
2021-11-02 |
2023-08-13 |
rat |
| Stephen R Edwards, Nemat Khan, Elizabeth J Coulson, Maree T Smit. Comparative studies of glial fibrillary acidic protein and brain-derived neurotrophic factor expression in two transgenic mouse models of Alzheimer's disease. Clinical and experimental pharmacology & physiology. vol 47. issue 10. 2021-10-29. PMID:32542833. |
we compared the expression of gfap, bdnf, and its precursor probdnf in the dorsal hippocampus of two transgenic ad mouse models. |
2021-10-29 |
2023-08-13 |
mouse |
| Ying Zhou, Qiuyun Tian, Chenfei Zheng, Jinge Yang, Junming Fan, Yangping Shent. Myocardial infarction-induced anxiety-like behavior is associated with epigenetic alterations in the hippocampus of rat. Brain research bulletin. vol 164. 2021-10-29. PMID:32871241. |
in addition, mi not only increased levels of il-1β, bax, and cleaved-caspase 3, but also increased iba-1 and gfap expression in the hippocampus, as compared to those in controls, suggesting a promotion of neuro-inflammation and apoptosis in hippocampus. |
2021-10-29 |
2023-08-13 |
rat |
| Yuanxin Huang, Lin Wang, Siying Ren, Guofeng Wu, Jing W. The Expression of ZnT3 and GFAP Is Potentiated in the Hippocampus of Drug-Resistant Epileptic Rats Induced by Amygdala Kindling. Neuroimmunomodulation. vol 27. issue 2. 2021-10-28. PMID:33161399. |
the expression of znt3 and gfap is potentiated in the hippocampus of drug-resistant epileptic rats induced by amygdala kindling. |
2021-10-28 |
2023-08-13 |
rat |
| Yuanxin Huang, Lin Wang, Siying Ren, Guofeng Wu, Jing W. The Expression of ZnT3 and GFAP Is Potentiated in the Hippocampus of Drug-Resistant Epileptic Rats Induced by Amygdala Kindling. Neuroimmunomodulation. vol 27. issue 2. 2021-10-28. PMID:33161399. |
here, we aimed to observe the ultrastructure changes and the expression of znt3 and gfap in the hippocampus of drug-resistant epileptic rats. |
2021-10-28 |
2023-08-13 |
rat |
| Johann Zwirner, Julia Lier, Heike Franke, Niels Hammer, Jakob Matschke, Florian Trautz, Rexon Tse, Benjamin Ondruschk. GFAP positivity in neurons following traumatic brain injuries. International journal of legal medicine. vol 135. issue 6. 2021-10-25. PMID:34114049. |
neuronal gfap staining was observed in the pericontusional zone and the ipsilateral hippocampus, but was absent in the contralateral cortex of tbi cases. |
2021-10-25 |
2023-08-13 |
Not clear |
| Xiaojuan Yin, Lei Dong, Wei Wei, Yu Wang, Yannan Chai, Zhichun Fen. Effect of mouse nerve growth factor on the expression of glial fibrillary acidic protein in hippocampus of neonatal rats with hypoxic-ischemic brain damage. Experimental and therapeutic medicine. vol 5. issue 2. 2021-10-21. PMID:23408790. |
after the rats were sacrificed, the expression of gfap in the hippocampus in the three groups was confirmed by immunohistochemical analysis. |
2021-10-21 |
2023-08-12 |
mouse |
| Xiaojuan Yin, Lei Dong, Wei Wei, Yu Wang, Yannan Chai, Zhichun Fen. Effect of mouse nerve growth factor on the expression of glial fibrillary acidic protein in hippocampus of neonatal rats with hypoxic-ischemic brain damage. Experimental and therapeutic medicine. vol 5. issue 2. 2021-10-21. PMID:23408790. |
the results revealed that the expression level of gfap in the ischemic side of the hippocampus in the mngf and hibd groups was higher compared with that in the control group at days 7 and 14 after surgery, respectively (p<0.01). |
2021-10-21 |
2023-08-12 |
mouse |
| Xiaojuan Yin, Lei Dong, Wei Wei, Yu Wang, Yannan Chai, Zhichun Fen. Effect of mouse nerve growth factor on the expression of glial fibrillary acidic protein in hippocampus of neonatal rats with hypoxic-ischemic brain damage. Experimental and therapeutic medicine. vol 5. issue 2. 2021-10-21. PMID:23408790. |
compared with day 7, the expression of gfap in the ischemic side of the hippocampus in the mngf group increased at 14 days (p<0.01), but decreased in the hibd group (p<0.01); however, this was still higher than that in the control group (p<0.01). |
2021-10-21 |
2023-08-12 |
mouse |