| Publication |
Sentence |
Publish Date |
Extraction Date |
Species |
| I. Suarez, G. Bodega, B. Fernande. Changes in Glial Fibrillary Acidic Protein Immunoreactivity in Response to Experimental Hepatic Encephalopathy in the Rat Hippocampus. Restorative neurology and neuroscience. vol 12. issue 1. 2019-11-20. PMID:12671320. |
these results show that long-term pca elicited different responses in gfap expression in different hippocampal regions, which might suggest a regional variation in glial sensitivity. |
2019-11-20 |
2023-08-12 |
rat |
| Mu-Huo Ji, Hui Tang, Dan Luo, Li-Li Qiu, Min Jia, Hong-Mei Yuan, Shan-Wu Feng, Jian-Jun Yan. Environmental conditions differentially affect neurobehavioral outcomes in a mouse model of sepsis-associated encephalopathy. Oncotarget. vol 8. issue 47. 2019-11-20. PMID:29137271. |
the expressions of proinflammatory cytokines (tumor necrosis factor (tnf-α), interleukin-1β (il-1β), il-6, il-10), ionized calcium-binding adaptor molecule-1 (iba1)-positive cells as well as glial fibrillary acidic protein (gfap)-positive cells, brain derived neurotrophic factor (bdnf), 5-bromo-2-deoxyuridine-labeled cells in the dentate gyrus of the hippocampus, and the number of dendritic spines in the hippocampal ca1 were determined. |
2019-11-20 |
2023-08-13 |
mouse |
| Teng Zhao, Ying Ding, Min Li, Chunkui Zhou, Weihong Li. Silencing lncRNA PVT1 inhibits activation of astrocytes and increases BDNF expression in hippocampus tissues of rats with epilepsy by downregulating the Wnt signaling pathway. Journal of cellular physiology. 2019-11-20. PMID:30805931. |
successfully modeled rats were grouped, and their spatial learning and memory, neuronal loss, number of tdt-mediated dutp nick labeling (tunel)-positive cells, and the expression of cleaved-caspase-3, pro-caspase-3, bax, bcl-2, gfap, bdnf, tumor necrosis factor-α (tnf-α), interleukin-1β (il-1β), il-6, axin, and cyclin d1 in hippocampus tissues were evaluated. |
2019-11-20 |
2023-08-13 |
rat |
| Teng Zhao, Ying Ding, Min Li, Chunkui Zhou, Weihong Li. Silencing lncRNA PVT1 inhibits activation of astrocytes and increases BDNF expression in hippocampus tissues of rats with epilepsy by downregulating the Wnt signaling pathway. Journal of cellular physiology. 2019-11-20. PMID:30805931. |
silencing of pvt1 improved spatial learning and memory, decreased neuronal loss, decreased the number of tunel-positive cell, decreased the expression of cleaved-caspase-3 and bax while increased pro-caspase-3 and bcl-2 expression, decreased the expression of gfap, increased the expression of bdnf, decreased the expression of tnf-α, il-1β, and il-6, and decreased the expression of axin and cyclin d1 in hippocampus tissues in epileptic rats. |
2019-11-20 |
2023-08-13 |
rat |
| Ronald B Pringle, Edward C Meek, Howard W Chambers, Janice E Chamber. Neuroprotection From Organophosphate-Induced Damage by Novel Phenoxyalkyl Pyridinium Oximes in Rat Brain. Toxicological sciences : an official journal of the Society of Toxicology. vol 166. issue 2. 2019-11-13. PMID:30496567. |
the histochemical astrocyte marker glial fibrillary acidic protein (gfap) was investigated as an indication of neuropathology in two brain regions, the piriform cortex and the dentate gyrus of the hippocampus, which are regions known to be damaged by nerve agent toxicity. |
2019-11-13 |
2023-08-13 |
rat |
| Maha Mohammed Abdel-Fattah, Basim Anwar Shehata Messiha, Ahmed Mohamed Mansou. Modulation of brain ACE and ACE2 may be a promising protective strategy against cerebral ischemia/reperfusion injury: an experimental trial in rats. Naunyn-Schmiedeberg's archives of pharmacology. vol 391. issue 9. 2019-10-31. PMID:29909460. |
histopathological examination and immunohistochemical evaluation of glial fibrillary acidic protein (gfap) were performed in cerebral cortex and hippocampus sections. |
2019-10-31 |
2023-08-13 |
rat |
| Erin R Hascup, Sarah O Broderick, Mary K Russell, Yimin Fang, Andrzej Bartke, Heather A Boger, Kevin N Hascu. Diet-induced insulin resistance elevates hippocampal glutamate as well as VGLUT1 and GFAP expression in AβPP/PS1 mice. Journal of neurochemistry. vol 148. issue 2. 2019-10-28. PMID:30472734. |
diet-induced insulin resistance elevates hippocampal glutamate as well as vglut1 and gfap expression in aβpp/ps1 mice. |
2019-10-28 |
2023-08-13 |
mouse |
| Laura Medina-Ceja, Fridha Villalpando-Vargas, Gloria I Girón de la Cruz, Adriana M Lara-Vazquez, Leopoldo Flores-Mancilla, Juan C Salazar-Sánchez, Alberto Morales-Villagrá. Effect of Chronic Krill Oil Supplement on Seizures Induced by Pentylenetetrazole in the Hippocampus of Adult Rats with Previous Febrile Seizures. Journal of food science. vol 84. issue 7. 2019-10-14. PMID:31218711. |
all animals' brains were processed by immunofluorescence against gfap, neun, and connexins (cx); cellular quantification was performed in hippocampus and pyramidal or granular layer thickness was evaluated with cresyl violet (cv) staining. |
2019-10-14 |
2023-08-13 |
rat |
| Manar A Nader, Hayam Ateyya, Mohamed El-Shafey, Nagla A El-Sherbeen. Sitagliptin enhances the neuroprotective effect of pregabalin against pentylenetetrazole-induced acute epileptogenesis in mice: Implication of oxidative, inflammatory, apoptotic and autophagy pathways. Neurochemistry international. vol 115. 2019-09-17. PMID:29032011. |
neuronal damage was also assessed by performing tissue staining by hematoxylin and eosin, estimating hippocampus level of glutamate, gamma-aminobutyric acid (gaba), glial fibrillary acidic protein (gfap) and brain-derived neurotrophic factor (bdnf). |
2019-09-17 |
2023-08-13 |
mouse |
| Penghui Song, Jing Hu, Xijin Liu, Xuejun Den. Increased expression of the P2X7 receptor in temporal lobe epilepsy: Animal models and clinical evidence. Molecular medicine reports. vol 19. issue 6. 2019-08-29. PMID:31059094. |
the aim of the present study was to assess the expression of p2x7r, glutamate (glu) and glial fibrillary acidic protein (gfap) in the temporal neocortex and hippocampus of rats with lithium‑pilocarpine‑induced epilepsy as well as in patients with intractable tle. |
2019-08-29 |
2023-08-13 |
rat |
| C Sathiya Priya, R Vidhya, K Kalpana, C V Anuradh. Indirubin-3'-monoxime prevents aberrant activation of GSK-3β/NF-κB and alleviates high fat-high fructose induced Aβ-aggregation, gliosis and apoptosis in mice brain. International immunopharmacology. vol 70. 2019-08-13. PMID:30856390. |
hffd fed-mice had significant amyloid deposits in cerebral cortex and hippocampus, and protein expression analyses showed activation of gsk-3β, nuclear translocation of nf-κb p65 and upregulation of inflammatory (tnf-α, il-6, cox-2), astrocytic (gfap), glial surface (cd-68) and pro-apoptotic markers (bax and caspase-3). |
2019-08-13 |
2023-08-13 |
mouse |
| Kaja Plucińska, Barry Crouch, Jie M Yeap, Sandra Stoppelkamp, Gernot Riedel, Bettina Plat. Histological and Behavioral Phenotypes of a Novel Mutated APP Knock-In Mouse. Journal of Alzheimer's disease : JAD. vol 65. issue 1. 2019-07-29. PMID:30040726. |
immunohistochemistry determined amyloid-β (aβ) pathology, astrogliosis (via gfap labelling), and neuronal densities in hippocampal and cortical brain regions. |
2019-07-29 |
2023-08-13 |
mouse |
| Gislaine Z Réus, Ritele H Silva, Airam B de Moura, Jaqueline F Presa, Helena M Abelaira, Mariane Abatti, Andriele Vieira, Bruna Pescador, Monique Michels, Zuleide M Ignácio, Felipe Dal-Pizzol, João Queved. Early Maternal Deprivation Induces Microglial Activation, Alters Glial Fibrillary Acidic Protein Immunoreactivity and Indoleamine 2,3-Dioxygenase during the Development of Offspring Rats. Molecular neurobiology. vol 56. issue 2. 2019-07-12. PMID:29873040. |
on pnd 10, it was found that there was a decrease in the level of glial fibrillary acidic protein (gfap) immunopositive cells, a decrease in the level of ido expression, and an increase in the level of iba-1 (microglial marker) in the hippocampus of rats that were subjected to md. |
2019-07-12 |
2023-08-13 |
rat |
| Gislaine Z Réus, Ritele H Silva, Airam B de Moura, Jaqueline F Presa, Helena M Abelaira, Mariane Abatti, Andriele Vieira, Bruna Pescador, Monique Michels, Zuleide M Ignácio, Felipe Dal-Pizzol, João Queved. Early Maternal Deprivation Induces Microglial Activation, Alters Glial Fibrillary Acidic Protein Immunoreactivity and Indoleamine 2,3-Dioxygenase during the Development of Offspring Rats. Molecular neurobiology. vol 56. issue 2. 2019-07-12. PMID:29873040. |
on pnd 20, levels of gfap were also found to have decreased in the hippocampus, and there was an increase in the level of iba-1 in the hippocampus. |
2019-07-12 |
2023-08-13 |
rat |
| Gislaine Z Réus, Ritele H Silva, Airam B de Moura, Jaqueline F Presa, Helena M Abelaira, Mariane Abatti, Andriele Vieira, Bruna Pescador, Monique Michels, Zuleide M Ignácio, Felipe Dal-Pizzol, João Queved. Early Maternal Deprivation Induces Microglial Activation, Alters Glial Fibrillary Acidic Protein Immunoreactivity and Indoleamine 2,3-Dioxygenase during the Development of Offspring Rats. Molecular neurobiology. vol 56. issue 2. 2019-07-12. PMID:29873040. |
on pnd 40, the levels of gfap were found to have increased in the hippocampus of rats that were subjected to md. |
2019-07-12 |
2023-08-13 |
rat |
| Patricia Rivera, María Del Mar Fernández-Arjona, Daniel Silva-Peña, Eduardo Blanco, Antonio Vargas, María Dolores López-Ávalos, Jesús M Grondona, Antonia Serrano, Francisco Javier Pavón, Fernando Rodríguez de Fonseca, Juan Suáre. Pharmacological blockade of fatty acid amide hydrolase (FAAH) by URB597 improves memory and changes the phenotype of hippocampal microglia despite ethanol exposure. Biochemical pharmacology. vol 157. 2019-07-08. PMID:30098312. |
regarding innate immune activity, urb597 specifically increased mrna levels of toll-like receptor 4 (tlr4), glial fibrillary acidic protein (gfap) and the chemokine stromal cell-derived factor 1 (sdf-1α/cxcl12), and elevated the cell population expressing the chemokine receptors cx3cr1, ccr2 and ccr4 in the ethanol-exposed rat hippocampus. |
2019-07-08 |
2023-08-13 |
rat |
| Javad Fahanik-Babaei, Tourandokht Baluchnejadmojarad, Farnaz Nikbakht, Mehrdad Roghan. Trigonelline protects hippocampus against intracerebral Aβ(1-40) as a model of Alzheimer's disease in the rat: insights into underlying mechanisms. Metabolic brain disease. vol 34. issue 1. 2019-06-06. PMID:30421246. |
additionally, trigonelline ameliorated hippocampal levels of glial fibrillary acidic protein (gfap), s100b, cyclooxygenase 2 (cox2), tumor necrosis factor α (tnfα), and interleukin 6 (il-6) with no significant alteration of inducible nitric oxide synthase (inos). |
2019-06-06 |
2023-08-13 |
rat |
| Sepideh Sadraie, Zahra Kiasalari, Mohadeseh Razavian, Shekoofe Azimi, Ladan Sedighnejad, Siamak Afshin-Majd, Tourandokht Baluchnejadmojarad, Mehrdad Roghan. Berberine ameliorates lipopolysaccharide-induced learning and memory deficit in the rat: insights into underlying molecular mechanisms. Metabolic brain disease. vol 34. issue 1. 2019-06-06. PMID:30456649. |
berberine also appropriately restored hippocampal 3-nitrotyrosine (3-nt), cyclooxygenase 2 (cox 2), glial fibrillary acidic protein (gfap), sirtuin 1, and mitogen-activated protein kinase (p38 mapk) with no significant alteration of brain-derived neurotrophic factor (bdnf). |
2019-06-06 |
2023-08-13 |
rat |
| Joan Y W Liu, Mar Matarin, Cheryl Reeves, Andrew W McEvoy, Anna Miserocchi, Pamela Thompson, Sanjay M Sisodiya, Maria Tho. Doublecortin-expressing cell types in temporal lobe epilepsy. Acta neuropathologica communications. vol 6. issue 1. 2019-06-04. PMID:30005693. |
the hippocampus (pes and body), parahippocampal gyrus, amygdala, temporal pole and temporal cortex were examined with dcx immunohistochemistry using four commercially-available dcx antibodies, labelled cells were quantified in different regions of interest as well as their co-expression with cell type specific markers (cd68, iba1, gfap, gfap∂, nestin, sox2, cd34, olig2, pdgfrβ, neun) and cell cycle marker (mcm2). |
2019-06-04 |
2023-08-13 |
Not clear |
| Ahsia M Clayton, Qingmei Shao, Nina D Paauw, Ashtin B Giambrone, Joey P Granger, Junie P Warringto. Postpartum increases in cerebral edema and inflammation in response to placental ischemia during pregnancy. Brain, behavior, and immunity. vol 70. 2019-05-21. PMID:29588233. |
western blot analysis showed no changes in astrocyte marker, glial fibrillary acidic protein (gfap); however, the microglia marker, ionized calcium binding adaptor molecule (iba1) tended to increase in hippocampus of rupp-exposed rats. |
2019-05-21 |
2023-08-13 |
rat |