| Publication |
Sentence |
Publish Date |
Extraction Date |
Species |
| Eduardo Fernandes Bondan, Carolina Vieira Cardoso, Maria de Fátima Monteiro Martins, Rosemari Otto. Memory impairments and increased GFAP expression in hippocampal astrocytes following hypercaloric diet in rats. Arquivos de neuro-psiquiatria. vol 77. issue 9. 2020-04-08. PMID:31553389. |
memory impairments and increased gfap expression in hippocampal astrocytes following hypercaloric diet in rats. |
2020-04-08 |
2023-08-13 |
rat |
| Eduardo Fernandes Bondan, Carolina Vieira Cardoso, Maria de Fátima Monteiro Martins, Rosemari Otto. Memory impairments and increased GFAP expression in hippocampal astrocytes following hypercaloric diet in rats. Arquivos de neuro-psiquiatria. vol 77. issue 9. 2020-04-08. PMID:31553389. |
as the hippocampus plays important roles in the consolidation of information, this investigation aimed to observe the memory function and the astrocyte expression of gfap in the hippocampus of rats that received either a hypercaloric or a normocaloric diet. |
2020-04-08 |
2023-08-13 |
rat |
| Linda Marschner, An Schreurs, Benoit Lechat, Jesper Mogensen, Anton Roebroek, Tariq Ahmed, Detlef Balschu. Single mild traumatic brain injury results in transiently impaired spatial long-term memory and altered search strategies. Behavioural brain research. vol 365. 2020-03-09. PMID:29499284. |
furthermore, western blot analysis showed a short-term increase in hippocampal gfap expression, most likely indicating astrogliosis, which is typically related to injuries of the central nervous system. |
2020-03-09 |
2023-08-13 |
Not clear |
| Shaobin Yang, Tingji Shao, Peng Yu, Ruidong Cao, Mingyu Zhang, Kang Wen, Maorong Fan, Bosheng H. Neuronostatin promotes soluble Aβ1-42 oligomers -induced spatial learning and memory impairments in mice. Behavioural brain research. vol 364. 2020-03-09. PMID:30753874. |
nst promoted oaβ (1 nmol/mouse) -induced cognitive impairments, subsequently co-injection of nst and oaβ increased the levels of gpr107 expression and pka phosphorylation, which also led to hyperactivation of gfap in the cortex and neuroinflammation cytokines (il-1β, il-6 and tnfα) both in the cortex and hippocampus. |
2020-03-09 |
2023-08-13 |
mouse |
| Haibo Zhang, Ding Wang, Ping Gong, Aihua Lin, Yan Zhang, Richard D Ye, Yang Y. Formyl Peptide Receptor 2 Deficiency Improves Cognition and Attenuates Tau Hyperphosphorylation and Astrogliosis in a Mouse Model of Alzheimer's Disease. Journal of Alzheimer's disease : JAD. vol 67. issue 1. 2020-03-02. PMID:30475772. |
in addition, the expression of gfap was significantly increased in hippocampus and cortex of icv-stz mice. |
2020-03-02 |
2023-08-13 |
mouse |
| Ane Wyssenbach, Tania Quintela, Francisco Llavero, Jose L Zugaza, Carlos Matute, Elena Alberd. Amyloid β-induced astrogliosis is mediated by β1-integrin via NADPH oxidase 2 in Alzheimer's disease. Aging cell. vol 15. issue 6. 2020-02-25. PMID:27709751. |
this mechanism promotes β1-integrin maturation, upregulation of nox2 and of the glial fibrillary acidic protein (gfap) in astrocytes in vitro and in hippocampal astrocytes in vivo. |
2020-02-25 |
2023-08-13 |
mouse |
| Ulrika Wilhelmsson, Andrea Pozo-Rodrigalvarez, Marie Kalm, Yolanda de Pablo, Åsa Widestrand, Marcela Pekna, Milos Pekn. The role of GFAP and vimentin in learning and memory. Biological chemistry. vol 400. issue 9. 2020-02-17. PMID:31063456. |
mice deficient for gfap and vimentin (gfap-/-vim-/-) exhibit increased post-traumatic synaptic plasticity and increased basal and post-traumatic hippocampal neurogenesis. |
2020-02-17 |
2023-08-13 |
mouse |
| Arindam Ghosh Mazumder, Vikram Patial, Damanpreet Sing. Mycophenolate mofetil contributes to downregulation of the hippocampal interleukin type 2 and 1β mediated PI3K/AKT/mTOR pathway hyperactivation and attenuates neurobehavioral comorbidities in a rat model of temporal lobe epilepsy. Brain, behavior, and immunity. vol 75. 2020-01-23. PMID:30243822. |
mtor, s6, ps6 and gfap protein expression was decreased, whereas neun was increased in the rat hippocampus of the treated animals. |
2020-01-23 |
2023-08-13 |
rat |
| Fengxia Li, Karen Liu, Ao Wang, Paul W R Harris, Mark H Vickers, Jian Gua. Cyclic glycine-proline administration normalizes high-fat diet-induced synaptophysin expression in obese rats. Neuropeptides. vol 76. 2020-01-23. PMID:31146894. |
the expression of hippocampal synaptophysin, glutamate receptor-1, gfap and striatal tyrosine-hydroxylase were also reduced in the hfd groups. |
2020-01-23 |
2023-08-13 |
rat |
| Xinyu Zhang, Xianzhi Shen, Jiali Dong, Wen-Cao Liu, Min Song, Yanyun Sun, Hui Shu, Clare-Louise Towse, Wenlan Liu, Chun-Feng Liu, Xinchun Ji. Inhibition of Reactive Astrocytes with Fluorocitrate Ameliorates Learning and Memory Impairment Through Upregulating CRTC1 and Synaptophysin in Ischemic Stroke Rats. Cellular and molecular neurobiology. vol 39. issue 8. 2020-01-20. PMID:31270712. |
deregulated glia gap junction communication, which is reflected by increased protein levels of glial fibrillary acidic protein (gfap) and connexin 43 (cx43), has been observed in ischemic hippocampus and has been associated with cognitive impairment in animal stroke models. |
2020-01-20 |
2023-08-13 |
rat |
| Xinyu Zhang, Xianzhi Shen, Jiali Dong, Wen-Cao Liu, Min Song, Yanyun Sun, Hui Shu, Clare-Louise Towse, Wenlan Liu, Chun-Feng Liu, Xinchun Ji. Inhibition of Reactive Astrocytes with Fluorocitrate Ameliorates Learning and Memory Impairment Through Upregulating CRTC1 and Synaptophysin in Ischemic Stroke Rats. Cellular and molecular neurobiology. vol 39. issue 8. 2020-01-20. PMID:31270712. |
our results showed that ischemic stroke caused significant memory impairment accompanied by increased protein levels of gfap and cx43 in hippocampal tissue. |
2020-01-20 |
2023-08-13 |
rat |
| Murat F Gorgun, Ming Zhuo, Kelly T Dineley, Ella W Englande. Elevated Neuroglobin Lessens Neuroinflammation and Alleviates Neurobehavioral Deficits Induced by Acute Inhalation of Combustion Smoke in the Mouse. Neurochemical research. vol 44. issue 9. 2020-01-20. PMID:31420834. |
specifically, we found that increases in hippocampal density of gfap and iba-1 positive cells that are detected post-smoke in wild-type mice are absent in the neuroglobin overexpressing transgenic (ngb-tg) mice. |
2020-01-20 |
2023-08-13 |
mouse |
| Haiyu Mu, Zhifei Wang, Xianjuan Zhang, Dongmeng Qian, Yuyang Wang, Shasha Jiang, Shuzhen Liang, Bin Wan. HCMV-encoded IE2 induces anxiety-depression and cognitive impairment in UL122 genetically-modified mice. International journal of clinical and experimental pathology. vol 12. issue 11. 2020-01-17. PMID:31933804. |
level of fibroblast growth factor 2 (fgf2) protein in the hippocampus cornu ammonia areas (ca1, ca3) and dentate gyrus (dg) of the experimental group was significantly lower, consistent with immunohistochemical staining and western blot for neuron-specific nuclear protein (neun) and glial fibrillary acidic protein (gfap). |
2020-01-17 |
2023-08-13 |
mouse |
| Kim Braeckman, Benedicte Descamps, Leen Pieters, Anne Vral, Karen Caeyenberghs, Christian Vanhov. Dynamic changes in hippocampal diffusion and kurtosis metrics following experimental mTBI correlate with glial reactivity. NeuroImage. Clinical. vol 21. 2020-01-03. PMID:30658945. |
furthermore, correlation analysis showed that increased values of fractional anisotropy one day post injury in the hippocampus was highly correlated with gfap reactivity three months post injury. |
2020-01-03 |
2023-08-13 |
rat |
| Kim Braeckman, Benedicte Descamps, Leen Pieters, Anne Vral, Karen Caeyenberghs, Christian Vanhov. Dynamic changes in hippocampal diffusion and kurtosis metrics following experimental mTBI correlate with glial reactivity. NeuroImage. Clinical. vol 21. 2020-01-03. PMID:30658945. |
additionally, we observed a positive correlation between gfap on one hand and the kurtosis parameters in the hippocampus on the other hand three months post injury. |
2020-01-03 |
2023-08-13 |
rat |
| Wen-Juan Yang, Hui-Zhong Wen, Lu-Xu Zhou, Yin-Pei Luo, Wen-Sheng Hou, Xing Wang, Xue-Long Tia. After-effects of repetitive anodal transcranial direct current stimulation on learning and memory in a rat model of Alzheimer's disease. Neurobiology of learning and memory. vol 161. 2019-12-24. PMID:30735789. |
hippocampal choline acetyltransferase (chat) and glial fibrillary acidic protein (gfap) immunohistochemical analyses were carried out after the last mwm assessment. |
2019-12-24 |
2023-08-13 |
rat |
| Huynh Nhu Mai, Lan Thuy Ty Nguyen, Eun-Joo Shin, Dae-Joong Kim, Ji Hoon Jeong, Yoon Hee Chung, Xin Gen Lei, Naveen Sharma, Choon-Gon Jang, Toshitaka Nabeshima, Hyoung-Chun Ki. Astrocytic mobilization of glutathione peroxidase-1 contributes to the protective potential against cocaine kindling behaviors in mice via activation of JAK2/STAT3 signaling. Free radical biology & medicine. vol 131. 2019-12-20. PMID:30592974. |
cocaine-induced glial fibrillary acidic protein (gfap)-labeled astrocytic level was significantly higher in the hippocampus of gpx-1 tg mice. |
2019-12-20 |
2023-08-13 |
mouse |
| Giovana Silva Leandro, Adriane Feijó Evangelista, Romulo Rebouças Lobo, Danilo Jordão Xavier, Julio César Moriguti, Elza Tiemi Sakamoto-Hoj. Changes in Expression Profiles Revealed by Transcriptomic Analysis in Peripheral Blood Mononuclear Cells of Alzheimer's Disease Patients. Journal of Alzheimer's disease : JAD. vol 66. issue 4. 2019-11-25. PMID:30400085. |
the results were compared with those of an independent study on hippocampus samples, and a number of genes in common between both studies were identified as potential peripheral biomarkers for ad, including dusp1, fos, slc7a2, rgs1, gfap, ccl2, angptl4, and sspn. |
2019-11-25 |
2023-08-13 |
Not clear |
| I. Suarez, G. Bodega, B. Fernande. Changes in Glial Fibrillary Acidic Protein Immunoreactivity in Response to Experimental Hepatic Encephalopathy in the Rat Hippocampus. Restorative neurology and neuroscience. vol 12. issue 1. 2019-11-20. PMID:12671320. |
gfap-immunopositive astroglial profiles were observed in all hippocampal layers in pca rats, but gfap distribution differed in pca rats and controls. |
2019-11-20 |
2023-08-12 |
rat |
| I. Suarez, G. Bodega, B. Fernande. Changes in Glial Fibrillary Acidic Protein Immunoreactivity in Response to Experimental Hepatic Encephalopathy in the Rat Hippocampus. Restorative neurology and neuroscience. vol 12. issue 1. 2019-11-20. PMID:12671320. |
in pca rats, cell bodies and cell processes immunostained with gfap were observed mainly in the ca1-ca3 layers in relation to pyramidal neurons, whereas the number and length of the astroglial processes decreased in the rest of the hippocampal regions. |
2019-11-20 |
2023-08-12 |
rat |