| Publication |
Sentence |
Publish Date |
Extraction Date |
Species |
| Yulin Zhu, Chao Lv, Jingying Liu, Shujun Shang, Wei Jin. Effects of sevoflurane general anesthesia during early pregnancy on AIM2 expression in the hippocampus and parietal cortex of Sprague-Dawley offspring rats. Experimental and therapeutic medicine. vol 21. issue 5. 2021-03-27. PMID:33767764. |
moreover, compared with the offspring of the s1 group, hippocampal and parietal cortex injury in the offspring of the s2 group was further aggravated, and the expression of gfap, aim2, cd45, il-1β, pro-caspase-1 and cleaved-caspase-1 was significantly increased (p<0.05). |
2021-03-27 |
2023-08-13 |
rat |
| Georgia-Ioanna Kartalou, Ana Rita Salgueiro-Pereira, Thomas Endres, Angelina Lesnikova, Plinio Casarotto, Paula Pousinha, Kevin Delanoe, Elke Edelmann, Eero Castrén, Kurt Gottmann, Hélène Marie, Volkmar Lessman. Anti-Inflammatory Treatment with FTY720 Starting after Onset of Symptoms Reverses Synaptic Deficits in an AD Mouse Model. International journal of molecular sciences. vol 21. issue 23. 2021-03-05. PMID:33255764. |
immunohistochemical analysis with markers of microgliosis (ionized calcium-binding adapter molecule 1; iba1) and astrogliosis (glial fibrillary acid protein; gfap) revealed that our fingolimod treatment regime strongly down regulated neuroinflammation in the hippocampus and neocortex of this ad model. |
2021-03-05 |
2023-08-13 |
mouse |
| Samantha L Hodges, Suzanne O Nolan, Lindsay A Tomac, Ilyasah D A Muhammad, Matthew S Binder, Joseph H Taube, Joaquin N Lug. Lipopolysaccharide-induced inflammation leads to acute elevations in pro-inflammatory cytokine expression in a mouse model of Fragile X syndrome. Physiology & behavior. vol 215. 2021-03-04. PMID:31838149. |
there were no differences in hippocampal protein expression between genotypes in microglia (iba1) or astrocyte (gfap) reactivity. |
2021-03-04 |
2023-08-13 |
mouse |
| Jorge Miguel Amaya, Ernst Suidgeest, Isabelle Sahut-Barnola, Typhanie Dumontet, Nathanaëlle Montanier, Guilhem Pagès, Cécile Keller, Louise van der Weerd, Alberto M Pereira, Antoine Martinez, Onno C Meije. Effects of Long-Term Endogenous Corticosteroid Exposure on Brain Volume and Glial Cells in the AdKO Mouse. Frontiers in neuroscience. vol 15. 2021-03-03. PMID:33642975. |
we also observed a decrease in the expression of glial fibrillary acidic protein (gfap, a marker for reactive astrocytes) and ionized calcium-binding adapter molecule 1 (iba1, a marker for activated microglia) in the cingulate regions of the anterior corpus callosum and the hippocampus. |
2021-03-03 |
2023-08-13 |
mouse |
| Qingzhen Liu, Lidong Zhang, Junfeng Zhan. Induced pluripotent stem cell-derived neural progenitor cell transplantation promotes regeneration and functional recovery after post-traumatic stress disorder in rats. Biomedicine & pharmacotherapy = Biomedecine & pharmacotherapie. vol 133. 2021-02-23. PMID:33186796. |
the results revealed that ipsc-npcs differentiated into neurons replacing the loss of hippocampus neurons, and ipsc-npcs transplantation showed higher expression of glial fibrillary acidic protein (gfap) and increased number of neun compared with the control group. |
2021-02-23 |
2023-08-13 |
human |
| Yiying Zhou, Xiang Wu, Luying Ye, Yujing Bai, Hui Zhang, Zhenquan Xuan, Yi Feng, Panpan Zhang, Yi Chen, Yushan Yan, Binbin Zhu, Wei Cu. Edaravone at high concentrations attenuates cognitive dysfunctions induced by abdominal surgery under general anesthesia in aged mice. Metabolic brain disease. vol 35. issue 2. 2021-01-29. PMID:31916204. |
edaravone could also decrease glial fibrillary acidic protein (gfap) and ionized calcium binding adaptor molecule-1 (iba-1) positive areas in the hippocampal regions of surgery mice, suggesting that edaravone might inhibit surgery-induced over-activation of microglia and astrocytes. |
2021-01-29 |
2023-08-13 |
mouse |
| Adriel Barrios-Anderson, Xiaodi Chen, Sakura Nakada, Ray Chen, Yow-Pin Lim, Barbara S Stonestree. Inter-alpha Inhibitor Proteins Modulate Neuroinflammatory Biomarkers After Hypoxia-Ischemia in Neonatal Rats. Journal of neuropathology and experimental neurology. 2020-12-08. PMID:31274164. |
hiaips reduced quantities of cortical gfap, hippocampal iba-1-positive microglia, corpus callosum mpo, and cortical mmp9-mpo cells and the percent of neutrophils in peripheral blood after hi in male, but not female rats. |
2020-12-08 |
2023-08-13 |
human |
| Xue Bai, Yan-Li Zhang, Li-Ning Li. Inhibition of TRIM8 restrains ischaemia-reperfusion-mediated cerebral injury by regulation of NF-κB activation associated inflammation and apoptosis. Experimental cell research. vol 388. issue 2. 2020-11-09. PMID:31917201. |
moreover, trim8 inhibition obviously repressed glial fibrillary acidic protein (gfap) expression in peri-hematoma cortex and hippocampus. |
2020-11-09 |
2023-08-13 |
mouse |
| Jianping Si, Yingyan Wang, Jing Xu, Jiwen Wan. Antiepileptic effects of exogenous β-hydroxybutyrate on kainic acid-induced epilepsy. Experimental and therapeutic medicine. vol 20. issue 6. 2020-10-28. PMID:33101467. |
hippocampal tissues were then obtained 1, 3 and 7 days following ka administration, following which the expression levels of neuron-specific enolase (nse) and glial fibrillary acidic protein (gfap) were measured using a double immunofluorescence labeling method. |
2020-10-28 |
2023-08-13 |
rat |
| Qi Guo, Jing Zhang, Zhaoshi Zheng, Xinxin Li, Fuli Wang, Songyan Li. Lentivirus-mediated microRNA-26a-modified neural stem cells improve brain injury in rats with cerebral palsy. Journal of cellular physiology. vol 235. issue 2. 2020-10-16. PMID:31264214. |
the neurobehavioral functions, morphology, and ultrastructure of cerebral cortex and hippocampus, apoptosis of brain cells, expression of apoptosis-related protein caspase-3 and bax, together with the expression of the glial fibrillary acidic protein (gfap) in cerebral cortex and hippocampus were determined. |
2020-10-16 |
2023-08-13 |
rat |
| Qi Guo, Jing Zhang, Zhaoshi Zheng, Xinxin Li, Fuli Wang, Songyan Li. Lentivirus-mediated microRNA-26a-modified neural stem cells improve brain injury in rats with cerebral palsy. Journal of cellular physiology. vol 235. issue 2. 2020-10-16. PMID:31264214. |
after nscs transplantation, the neurobehavioral status of cp rats was improved, the degree of brain pathological injury was alleviated, the apoptotic index of cells in cerebral cortex and hippocampus and the expression of the apoptotic protein (caspase-3 and bax) were decreased, the expression of gfap were significantly decreased. |
2020-10-16 |
2023-08-13 |
rat |
| Yingying Huang, Yingjun Liao, Huijun Zhang, Shuyun L. Lead exposure induces cell autophagy via blocking the Akt/mTOR signaling in rat astrocytes. The Journal of toxicological sciences. vol 45. issue 9. 2020-10-09. PMID:32879255. |
the expression levels of gfap, lc3, and p62 in the rat hippocampus were detected by immunofluorescence and western blot after lead exposure. |
2020-10-09 |
2023-08-13 |
human |
| Yingying Huang, Yingjun Liao, Huijun Zhang, Shuyun L. Lead exposure induces cell autophagy via blocking the Akt/mTOR signaling in rat astrocytes. The Journal of toxicological sciences. vol 45. issue 9. 2020-10-09. PMID:32879255. |
we found that lead exposure induced activation of astrocytes, as evidenced by increased gfap levels and gfap-positive staining cells in the rat hippocampus. |
2020-10-09 |
2023-08-13 |
human |
| Chia-Yang Hung, Tsung-I Hsu, Jian-Ying Chuang, Tsung-Ping Su, Wen-Chang Chang, Jan-Jong Hun. Sp1 in Astrocyte Is Important for Neurite Outgrowth and Synaptogenesis. Molecular neurobiology. vol 57. issue 1. 2020-10-07. PMID:31317491. |
knockout of sp1 in astrocytes altered astrocytic morphology and decreased gfap expression in the cortex and hippocampus but did not affect cell viability. |
2020-10-07 |
2023-08-13 |
mouse |
| Seung-Soo Baek, Sang-Hoon Ki. Treadmill exercise ameliorates symptoms of Alzheimer disease through suppressing microglial activation-induced apoptosis in rats. Journal of exercise rehabilitation. vol 12. issue 6. 2020-10-01. PMID:28119873. |
expressions of glial fibrillary acidic protein (gfap) and cluster of differentiation molecule 11b (cd11b) in the hippocampal dentate gyrus were increased in the ad rats, in contrast, treadmill exercise suppressed gfap and cd11b expressions. |
2020-10-01 |
2023-08-13 |
rat |
| Xiu-Fang Ding, Yan Liu, Zhi-Yi Yan, Xiao-Juan Li, Qing-Yu Ma, Zhong-Ye Jin, Yan Liu, Yue-Hua Li, Yue-Yun Liu, Zhe Xue, Jia-Xu Chen, Zhi-Ping L. Involvement of Normalized Glial Fibrillary Acidic Protein Expression in the Hippocampi in Antidepressant-Like Effects of Xiaoyaosan on Chronically Stressed Mice. Evidence-based complementary and alternative medicine : eCAM. vol 2017. 2020-10-01. PMID:28348623. |
the protein and mrna expressions and the immunoreactivities of glial fibrillary acidic protein (gfap) and neuronal nuclei (neun) in mouse hippocampus were detected using a western blot, qrt-pcr, and immunohistochemical staining, respectively. |
2020-10-01 |
2023-08-13 |
mouse |
| Xiu-Fang Ding, Yan Liu, Zhi-Yi Yan, Xiao-Juan Li, Qing-Yu Ma, Zhong-Ye Jin, Yan Liu, Yue-Hua Li, Yue-Yun Liu, Zhe Xue, Jia-Xu Chen, Zhi-Ping L. Involvement of Normalized Glial Fibrillary Acidic Protein Expression in the Hippocampi in Antidepressant-Like Effects of Xiaoyaosan on Chronically Stressed Mice. Evidence-based complementary and alternative medicine : eCAM. vol 2017. 2020-10-01. PMID:28348623. |
xys treatment also elevated the protein and mrna levels, as well as the immunoreactivity of gfap in the hippocampus. |
2020-10-01 |
2023-08-13 |
mouse |
| Xiaoqin Zhang, Dongpi Wang, Hongyu Pan, Binggui Su. Enhanced Expression of Markers for Astrocytes in the Brain of a Line of GFAP-TK Transgenic Mice. Frontiers in neuroscience. vol 11. 2020-10-01. PMID:28446865. |
037351-unc) generated in dr. heather cameron's laboratory in nih, however, no difference in gfap and vimentin expression was found in both hippocampus and cortex, regardless of gcv treatment or not. |
2020-10-01 |
2023-08-13 |
mouse |
| Giada Frenzilli, Larisa Ryskalin, Michela Ferrucci, Emanuela Cantafora, Silvia Chelazzi, Filippo S Giorgi, Paola Lenzi, Vittoria Scarcelli, Alessandro Frati, Francesca Biagioni, Stefano Gambardella, Alessandra Falleni, Francesco Forna. Loud Noise Exposure Produces DNA, Neurotransmitter and Morphological Damage within Specific Brain Areas. Frontiers in neuroanatomy. vol 11. 2020-10-01. PMID:28694773. |
this is in line with pathological findings within striatum and hippocampus consisting of a decrease in striatal tyrosine hydroxylase (th) combined with increased bax and glial fibrillary acidic protein (gfap). |
2020-10-01 |
2023-08-13 |
human |
| Paul B Bernard, Leslie A Ramsay, Debra S MacDonald, R Andrew Taske. Progressive changes in hippocampal cytoarchitecture in a neurodevelopmental rat model of epilepsy: implications for understanding presymptomatic epileptogenesis, predictive diagnosis, and targeted treatments. The EPMA journal. vol 8. issue 3. 2020-10-01. PMID:29021835. |
postmortem hippocampal tissue was obtained on postnatal days 29, 64, and 90 and processed for glial fibrillary acidic protein (gfap), neun, and calbindin expression. |
2020-10-01 |
2023-08-13 |
rat |