| Publication |
Sentence |
Publish Date |
Extraction Date |
Species |
| P C Konturek, T Brzozowski, S J Konturek, H Ernst, D Drozdowicz, R Pajdo, E G Hah. Expression of epidermal growth factor and transforming growth factor alpha during ulcer healing. Time sequence study. Scandinavian journal of gastroenterology. vol 32. issue 1. 1997-04-15. PMID:9018760. |
in this study the rate of cell proliferation and the gastric secretion and gene expression of mrna for egf and tgf alpha were determined during ulcer healing. |
1997-04-15 |
2023-08-12 |
Not clear |
| A Sjöhol. Effects of transforming growth factor beta, tumor necrosis factor alpha and interferon gamma on pancreatic islet beta-cell responsiveness to transforming growth factor alpha. Bioscience reports. vol 16. issue 5. 1997-04-14. PMID:8913531. |
the insulin-producing pancreatic islet beta-cell, characterized by low proliferative potential, is normally not responsive to the polypeptide epidermal growth factor (egf) or its homolog transforming growth factor alpha (tgf-alpha). |
1997-04-14 |
2023-08-12 |
rat |
| A Sjöhol. Effects of transforming growth factor beta, tumor necrosis factor alpha and interferon gamma on pancreatic islet beta-cell responsiveness to transforming growth factor alpha. Bioscience reports. vol 16. issue 5. 1997-04-14. PMID:8913531. |
since egf receptors in other tissues can be up-regulated by other growth factors and by cytokines, we have in this paper investigated whether such a beta-cell responsiveness to tgf-alpha, or egf, can be conferred by co-culture with interferon gamma (ifn-gamma), tumor necrosis factor alpha (tnf-alpha) or transforming growth factor beta (tgf-beta) in various combinations. |
1997-04-14 |
2023-08-12 |
rat |
| D Wang, E Yang, L Y Chen. Effects of IFN-gamma, TNF-alpha and EGF on the expression of HLA class I antigen and the proliferation of human hepatocellular carcinoma HepG2 cells. Anticancer research. vol 17. issue 1A. 1997-04-07. PMID:9066649. |
in this study, the effects of ifn gamma, tnf alpha and egf on the expression of hla class i antigen and the proliferation of human hepatocellular carcinoma-hepg2 cells were investigated. |
1997-04-07 |
2023-08-12 |
human |
| N Reddy, A Everhart, T Eling, W Glasgo. Characterization of a 15-lipoxygenase in human breast carcinoma BT-20 cells: stimulation of 13-HODE formation by TGF alpha/EGF. Biochemical and biophysical research communications. vol 231. issue 1. 1997-04-07. PMID:9070230. |
egf and tgf alpha stimulated dna synthesis in these cells which was attenuated by the addition of a lipoxygenase inhibitor, ndga. |
1997-04-07 |
2023-08-12 |
human |
| N Reddy, A Everhart, T Eling, W Glasgo. Characterization of a 15-lipoxygenase in human breast carcinoma BT-20 cells: stimulation of 13-HODE formation by TGF alpha/EGF. Biochemical and biophysical research communications. vol 231. issue 1. 1997-04-07. PMID:9070230. |
the formation of 13-hode was inhibited by the addition of ndga and was dependent on egf or tgf alpha. |
1997-04-07 |
2023-08-12 |
human |
| K S Schluns, J E Cook, P T L. TGF-beta differentially modulates epidermal growth factor-mediated increases in leukemia-inhibitory factor, IL-6, IL-1 alpha, and IL-1 beta in human thymic epithelial cells. Journal of immunology (Baltimore, Md. : 1950). vol 158. issue 6. 1997-04-02. PMID:9058804. |
we established that a single tec expresses both egf receptor and tgf-beta r. tgf-beta plus egf synergistically increased leukemia-inhibitory factor (lif), additively increased il-6, but had little effect on il-1 alpha and il-1 beta mrna levels. |
1997-04-02 |
2023-08-12 |
human |
| D J Perkins, D A Knis. Rapid and transient induction of cyclo-oxygenase 2 by epidermal growth factor in human amnion-derived WISH cells. The Biochemical journal. vol 321 ( Pt 3). 1997-03-13. PMID:9032453. |
preincubation of cells in dexamethasone (dex; 0.1 microm), however, resulted in only a 31% decrease in pge2 formation in response to egf (10 ng/ml) while completely attenuating pge2 biosynthesis in tumour necrosis factor alpha (tnf-alpha)-stimulated cells. |
1997-03-13 |
2023-08-12 |
human |
| M F Crouch, L Simso. The G-protein G(i) regulates mitosis but not DNA synthesis in growth factor-activated fibroblasts: a role for the nuclear translocation of G(i). FASEB journal : official publication of the Federation of American Societies for Experimental Biology. vol 11. issue 2. 1997-03-11. PMID:9039962. |
we suggest that translocation of g(i alpha) to the nucleus induced by either thrombin or egf may occur without subunit dissociation. |
1997-03-11 |
2023-08-12 |
Not clear |
| T Hosono, A Ito, T Sato, H Nagase, Y Mor. Translational augmentation of pro-matrix metalloproteinase 3 (prostromelysin 1) and a tissue inhibitor of metalloproteinases (TIMP)-1 mRNAs by epidermal growth factor and transforming growth factor alpha, but not by interleukin 1 alpha or 12-O-tetradecanoylphorbol 13-acetate in human uterine cervical fibroblasts: the possible involvement of an atypical protein kinase C. Biological & pharmaceutical bulletin. vol 19. issue 10. 1997-03-06. PMID:8913498. |
translational augmentation of pro-matrix metalloproteinase 3 (prostromelysin 1) and a tissue inhibitor of metalloproteinases (timp)-1 mrnas by epidermal growth factor and transforming growth factor alpha, but not by interleukin 1 alpha or 12-o-tetradecanoylphorbol 13-acetate in human uterine cervical fibroblasts: the possible involvement of an atypical protein kinase c. we have previously reported that epidermal growth factor (egf) augments the translation of pro-matrix metalloproteinase 3 (prommp-3/prostromelysin 1) and tissue inhibitor of metalloproteinases (timp)-1 mrnas during the first 1-h treatment of human uterine cervical fibroblasts (hosono, t. et al., febs lett., 381, 115-118, (1996)). |
1997-03-06 |
2023-08-12 |
human |
| T Hosono, A Ito, T Sato, H Nagase, Y Mor. Translational augmentation of pro-matrix metalloproteinase 3 (prostromelysin 1) and a tissue inhibitor of metalloproteinases (TIMP)-1 mRNAs by epidermal growth factor and transforming growth factor alpha, but not by interleukin 1 alpha or 12-O-tetradecanoylphorbol 13-acetate in human uterine cervical fibroblasts: the possible involvement of an atypical protein kinase C. Biological & pharmaceutical bulletin. vol 19. issue 10. 1997-03-06. PMID:8913498. |
these results suggest that egf and tgf alpha, but not il-1 alpha and tpa, specifically augment the translation of prommp-3 and timp-1 mrnas and accelerate their accumulation without modifying their transcripts during the first 1-2 h treatment of human uterine cervical fibroblasts. |
1997-03-06 |
2023-08-12 |
human |
| T K Guren, G H Thoresen, O F Dajani, E Taraldsrud, E R Moberg, T Christofferse. Epidermal growth factor behaves as a partial agonist in hepatocytes: effects on DNA synthesis in primary culture and competition with transforming growth factor alpha. Growth factors (Chur, Switzerland). vol 13. issue 3-4. 1997-03-03. PMID:8919025. |
the structurally related mitogens epidermal growth factor (egf) and transforming growth factor (alpha (tgfalpha) are believed to exert all their effects via the same receptor. |
1997-03-03 |
2023-08-12 |
rat |
| J J Bond, P C Wynn, G P Moor. Effects of epidermal growth factor and transforming growth factor alpha on the function of wool follicles in culture. Archives of dermatological research. vol 288. issue 7. 1997-02-21. PMID:8818185. |
the development of a procedure to culture wool follicles from merino sheep in serum-free conditions has enabled us to investigate the actions of epidermal growth factor (egf) and transforming growth factor alpha (tgf alpha) on follicle function, including fibre growth. |
1997-02-21 |
2023-08-12 |
Not clear |
| J J Bond, P C Wynn, G P Moor. Effects of epidermal growth factor and transforming growth factor alpha on the function of wool follicles in culture. Archives of dermatological research. vol 288. issue 7. 1997-02-21. PMID:8818185. |
the observations that cell proliferation continued in the bulb, that glycogen was present and that soft keratins were expressed in these cells suggest that the bulb cell population was induced to differentiate into an ors phenotype by egf and tgf alpha. |
1997-02-21 |
2023-08-12 |
Not clear |
| E Suarez Pestana, U Greiser, B Sánchez, L E Fernández, A Lage, R Perez, F D Böhme. Growth inhibition of human lung adenocarcinoma cells by antibodies against epidermal growth factor receptor and by ganglioside GM3: involvement of receptor-directed protein tyrosine phosphatase(s). British journal of cancer. vol 75. issue 2. 1997-02-20. PMID:9010029. |
thus, the possibility of an egf receptor-directed antiproliferative treatment was investigated in vitro using a monoclonal antibody (alpha egfr ior egf/r3) against the human egf receptor and gangliosides which are known to possess antiproliferative and anti-tyrosine kinase activity. |
1997-02-20 |
2023-08-12 |
human |
| E Suarez Pestana, U Greiser, B Sánchez, L E Fernández, A Lage, R Perez, F D Böhme. Growth inhibition of human lung adenocarcinoma cells by antibodies against epidermal growth factor receptor and by ganglioside GM3: involvement of receptor-directed protein tyrosine phosphatase(s). British journal of cancer. vol 75. issue 2. 1997-02-20. PMID:9010029. |
likewise, the combination of alpha egfr ior egf/r3 and gm3 inhibited egf receptor autophosphorylation activity in h125 cells more strongly than either agent alone. |
1997-02-20 |
2023-08-12 |
human |
| E Suarez Pestana, U Greiser, B Sánchez, L E Fernández, A Lage, R Perez, F D Böhme. Growth inhibition of human lung adenocarcinoma cells by antibodies against epidermal growth factor receptor and by ganglioside GM3: involvement of receptor-directed protein tyrosine phosphatase(s). British journal of cancer. vol 75. issue 2. 1997-02-20. PMID:9010029. |
a synergistic inhibition of egf receptor autophosphorylation by alpha egfr ior egf/r3 and gm3 was also observed in the human epidermoid carcinoma cell line a431. |
1997-02-20 |
2023-08-12 |
human |
| N S Krishna, S S Little, T V Getchel. Epidermal growth factor receptor mRNA and protein are expressed in progenitor cells of the olfactory epithelium. The Journal of comparative neurology. vol 373. issue 2. 1997-02-19. PMID:8889929. |
although the factors that regulate this process in vivo are not known, recent in vitro studies demonstrated that members of the epidermal growth factor (egf) family including transforming growth factor-alpha (tgf alpha) and egf are highly potent in promoting the proliferation of progenitor cells, suggesting a role for the egf receptor (egfr), which is the molecular receptor for both mitogens. |
1997-02-19 |
2023-08-12 |
Not clear |
| N S Krishna, S S Little, T V Getchel. Epidermal growth factor receptor mRNA and protein are expressed in progenitor cells of the olfactory epithelium. The Journal of comparative neurology. vol 373. issue 2. 1997-02-19. PMID:8889929. |
these results suggest that egfr mediates the mitogenic effect of tgf alpha and/or egf on the quiescent basal cells to initiate the cell cycle. |
1997-02-19 |
2023-08-12 |
Not clear |
| N Bernardini, F Bianchi, M Lupetti, A Dolf. Immunohistochemical localization of the epidermal growth factor, transforming growth factor alpha, and their receptor in the human mesonephros and metanephros. Developmental dynamics : an official publication of the American Association of Anatomists. vol 206. issue 3. 1997-02-19. PMID:8896979. |
the distribution of epidermal growth factor (egf), transforming growth factor alpha (tgf alpha), and egf/tgf alpha receptor were studied by means of immunohistochemical methods starting from the very early stages of human embryonic kidney development. |
1997-02-19 |
2023-08-12 |
human |