| Publication |
Sentence |
Publish Date |
Extraction Date |
Species |
| Jane Yellowlees Douglas, Ashay D Bhatwadekar, Sergio Li Calzi, Lynn C Shaw, Debra Carnegie, Sergio Caballero, Quihong Li, Alan W Stitt, Mohan K Raizada, Maria B Gran. Bone marrow-CNS connections: implications in the pathogenesis of diabetic retinopathy. Progress in retinal and eye research. vol 31. issue 5. 2012-10-04. PMID:22609081. |
the resulting systemic inflammation further impacts the hypothalamus, promoting insulin resistance and diabetes, and initiates an inflammatory cascade that adversely impacts both macrovascular and microvascular complications, including diabetic retinopathy (dr). |
2012-10-04 |
2023-08-12 |
Not clear |
| Stuart J Brin. [Harry Dorchy and pediatric diabetology]. Revue medicale de Bruxelles. vol 31. issue 2 Suppl. 2011-09-27. PMID:21812214. |
dr dorchy's research has complemented his superb work as a clinician : screening for subclinical complications, normal and flexible diet, physical activity, glycemic control and insulin treatment, quality of life, genetics and immunology, specific types of diabetes, etc. |
2011-09-27 |
2023-08-12 |
Not clear |
| J E de Leeuw van Weenen, E T Parlevliet, J P Schröder-van der Elst, S A van den Berg, K Willems van Dijk, J A Romijn, H Pij. Pharmacological modulation of dopamine receptor D2-mediated transmission alters the metabolic phenotype of diet induced obese and diet resistant C57Bl6 mice. Experimental diabetes research. vol 2011. 2011-09-09. PMID:21603181. |
compared to diet resistant (dr) rodents, diet induced obese (dio) rodents are insulin resistant and have a reduced dopamine receptor d2 (drd2) mediated tone. |
2011-09-09 |
2023-08-12 |
mouse |
| J E de Leeuw van Weenen, E T Parlevliet, J P Schröder-van der Elst, S A van den Berg, K Willems van Dijk, J A Romijn, H Pij. Pharmacological modulation of dopamine receptor D2-mediated transmission alters the metabolic phenotype of diet induced obese and diet resistant C57Bl6 mice. Experimental diabetes research. vol 2011. 2011-09-09. PMID:21603181. |
compared to dr mice, the bodyweight of dio mice was higher and their insulin sensitivity decreased. |
2011-09-09 |
2023-08-12 |
mouse |
| J E de Leeuw van Weenen, E T Parlevliet, J P Schröder-van der Elst, S A van den Berg, K Willems van Dijk, J A Romijn, H Pij. Pharmacological modulation of dopamine receptor D2-mediated transmission alters the metabolic phenotype of diet induced obese and diet resistant C57Bl6 mice. Experimental diabetes research. vol 2011. 2011-09-09. PMID:21603181. |
haloperidol treatment reduced the voluntary activity and energy expenditure of dr mice and induced insulin resistance in these mice. |
2011-09-09 |
2023-08-12 |
mouse |
| H Kübra Elçioğlu, Levent Kabasakal, Naziye Özkan, Çiğdem Çelikel, Gül Ayanoğlu-Dülge. A study comparing the effects of rosiglitazone and/or insulin treatments on streptozotocin induced diabetic (type I diabetes) rat aorta and cavernous tissues. European journal of pharmacology. vol 660. issue 2-3. 2011-09-06. PMID:21463620. |
48 h after streptozotocin injection, animals were divided into 4 subgroups (n=6 for each group); a) no treatment group (d), b) treated with rosiglitazone (4 mg/kg/day) (dr), c) treated with insulin (6 u/kg/day) (di) and d) treated with insulin and rosiglitazone (dri) for 8 weeks. |
2011-09-06 |
2023-08-12 |
rat |
| Marc Tata. The plate half-full: status of research on the mechanisms of dietary restriction in Drosophila melanogaster. Experimental gerontology. vol 46. issue 5. 2011-08-17. PMID:21187139. |
in reviewing the best data, there is little evidence to date for any gene to be required for dr to increase drosophila lifespan, including insulin signaling or 4ebp. |
2011-08-17 |
2023-08-12 |
drosophila_melanogaster |
| Rana J Ei Wafai, Hania Nakkash Chmaisse, Rajaa F Makki, Hana Fakhour. Association of HLA class II alleles and CTLA-4 polymorphism with type 1 diabetes. Saudi journal of kidney diseases and transplantation : an official publication of the Saudi Center for Organ Transplantation, Saudi Arabia. vol 22. issue 2. 2011-05-18. PMID:21422625. |
hla class ii alleles on chromosome 6p21 [insulin dependent diabetes mellitus 1 (iddm1)], especially dr and dq, show strong association with t1dm. |
2011-05-18 |
2023-08-12 |
Not clear |
| Jianghua Lu, Lezi E, Wenfang Wang, Jennifer Frontera, Hao Zhu, Wen-Tung Wang, Phil Lee, In Young Choi, William M Brooks, Jeffrey M Burns, Daniel Aires, Russell H Swerdlo. Alternate day fasting impacts the brain insulin-signaling pathway of young adult male C57BL/6 mice. Journal of neurochemistry. vol 117. issue 1. 2011-05-16. PMID:21244426. |
dr in general appeared to enhance insulin sensitivity. |
2011-05-16 |
2023-08-12 |
mouse |
| C E Ash, B J Merr. The molecular basis by which dietary restricted feeding reduces mitochondrial reactive oxygen species generation. Mechanisms of ageing and development. vol 132. issue 1-2. 2011-05-09. PMID:21172374. |
the adenine nucleotide translocase (ant) was shown to be the dominant proton leak channel induced under dr feeding regimes in these tissues, while in brown fat mitochondria, ucp1 was activated, but this was not sensitive to exogenous insulin treatment. |
2011-05-09 |
2023-08-12 |
Not clear |
| C E Ash, B J Merr. The molecular basis by which dietary restricted feeding reduces mitochondrial reactive oxygen species generation. Mechanisms of ageing and development. vol 132. issue 1-2. 2011-05-09. PMID:21172374. |
mobilisation of nefa under dr feeding, when insulin plasma concentrations are extremely low, explains the indirect action of insulin to counteract the effects of dr feeding on mitochondrial ros generation. |
2011-05-09 |
2023-08-12 |
Not clear |
| Philippe Katchunga, Michel P Hermans, Baudouin Manwa, François Lepira, Zacharie Kashongwe, Jean-René M'Buyamba-Kabang. [Hypertension, insulin resistance and chronic kidney disease in type 2 diabetes patients from South Kivu, DR Congo]. Nephrologie & therapeutique. vol 6. issue 6. 2011-03-29. PMID:20605543. |
[hypertension, insulin resistance and chronic kidney disease in type 2 diabetes patients from south kivu, dr congo]. |
2011-03-29 |
2023-08-12 |
Not clear |
| Larry A Weinrauch, Jennifer Sun, Ray E Gleason, Guenther H Boden, R H Creech, George Dailey, Frank P Kennedy, Matthew R Weir, John A D'Eli. Pulsatile intermittent intravenous insulin therapy for attenuation of retinopathy and nephropathy in type 1 diabetes mellitus. Metabolism: clinical and experimental. vol 59. issue 10. 2010-10-27. PMID:20189608. |
statistically significant preservation of renal function by pulsatile insulin infusion was not matched by a statistically significant prevention of dr progression compared with standard diabetes care. |
2010-10-27 |
2023-08-12 |
human |
| Li-Ying Liu, Fang-Tian Dong, Hui L. [Relationship between the classification of diabetic macular edema and its related factors]. Zhongguo yi xue ke xue yuan xue bao. Acta Academiae Medicinae Sinicae. vol 29. issue 6. 2010-06-10. PMID:18595262. |
to explore the relationship between the classification and degree of diabetic macular edema (dme) and the stages of diabetic retinopathy (dr), diabetic duration, classification of diabetes, use of insulin, and visual loss. |
2010-06-10 |
2023-08-12 |
Not clear |
| Raylene A Reimer, Alannah D Maurer, David C W Lau, Roland N Aue. Long-term dietary restriction influences plasma ghrelin and GOAT mRNA level in rats. Physiology & behavior. vol 99. issue 5. 2010-06-09. PMID:20149910. |
plasma leptin and insulin were lower in adult dr and young al rats compared to adult al. |
2010-06-09 |
2023-08-12 |
rat |
| Brian Onken, Monica Driscol. Metformin induces a dietary restriction-like state and the oxidative stress response to extend C. elegans Healthspan via AMPK, LKB1, and SKN-1. PloS one. vol 5. issue 1. 2010-05-20. PMID:20090912. |
genetic data suggest that metformin acts through a mechanism similar to that operative in eating-impaired dietary restriction (dr) mutants, but independent of the insulin signaling pathway. |
2010-05-20 |
2023-08-12 |
mouse |
| Futoshi Anan, Takayuki Masaki, Yuji Ito, Takahiko Eto, Yoshikazu Umeno, Nobuoki Eshima, Tetsunori Saikawa, Hironobu Yoshimats. Diabetic retinopathy is associated with visceral fat accumulation in Japanese type 2 diabetes mellitus patients. Metabolism: clinical and experimental. vol 59. issue 3. 2010-03-15. PMID:20004426. |
this preliminary study was therefore designed to test the hypothesis that dr is associated with insulin resistance and vfa in type 2 diabetes mellitus patients without insulin treatment. |
2010-03-15 |
2023-08-12 |
Not clear |
| Futoshi Anan, Takayuki Masaki, Yuji Ito, Takahiko Eto, Yoshikazu Umeno, Nobuoki Eshima, Tetsunori Saikawa, Hironobu Yoshimats. Diabetic retinopathy is associated with visceral fat accumulation in Japanese type 2 diabetes mellitus patients. Metabolism: clinical and experimental. vol 59. issue 3. 2010-03-15. PMID:20004426. |
fasting plasma glucose (p < .0005), insulin concentrations (p < .0001), homeostasis model assessment index (p < .0001), and vfa (p < .0001) levels were higher in the dr group than in the ndr group. |
2010-03-15 |
2023-08-12 |
Not clear |
| Futoshi Anan, Takayuki Masaki, Yuji Ito, Takahiko Eto, Yoshikazu Umeno, Nobuoki Eshima, Tetsunori Saikawa, Hironobu Yoshimats. Diabetic retinopathy is associated with visceral fat accumulation in Japanese type 2 diabetes mellitus patients. Metabolism: clinical and experimental. vol 59. issue 3. 2010-03-15. PMID:20004426. |
multivariate logistic analysis revealed that dr was independently predicted by high vfa and insulin resistance. |
2010-03-15 |
2023-08-12 |
Not clear |
| Futoshi Anan, Takayuki Masaki, Yuji Ito, Takahiko Eto, Yoshikazu Umeno, Nobuoki Eshima, Tetsunori Saikawa, Hironobu Yoshimats. Diabetic retinopathy is associated with visceral fat accumulation in Japanese type 2 diabetes mellitus patients. Metabolism: clinical and experimental. vol 59. issue 3. 2010-03-15. PMID:20004426. |
the results of this preliminary study indicate that the presence of dr was associated with high vfa and insulin resistance in japanese patients with type 2 diabetes mellitus. |
2010-03-15 |
2023-08-12 |
Not clear |