| Publication |
Sentence |
Publish Date |
Extraction Date |
Species |
| P MacKay, A Boulton, A Rabinovitc. Lymphoid cells of BB/W diabetic rats are cytotoxic to islet beta cells in vitro. Diabetes. vol 34. issue 7. 1985-08-02. PMID:3891476. |
dp cells also significantly reduced the insulin content in wf rat islet (-20%) and rin cultures (-63%), whereas dr cells had no significant effect. |
1985-08-02 |
2023-08-11 |
rat |
| J B Roullet, B Lacour, J P Yvert, J J Prat, T Druek. Factors of increase in serum triglyceride-rich lipoproteins in uremic rats. Kidney international. vol 27. issue 2. 1985-06-19. PMID:3886997. |
serum insulin concentration was significantly decreased in u rats as compared to c and dr rats in both series. |
1985-06-19 |
2023-08-11 |
rat |
| H Allannic, R Fauchet, M Gueguen, H Pheng Savath, T Dinh Knoi, B Genete. Factor B (Bf) and glyoxalase genes in insulin-dependent diabetes mellitus. Diabete & metabolisme. vol 11. issue 1. 1985-05-08. PMID:3856541. |
b and dr and to the bf loci confer susceptibility to insulin dependent diabetes. |
1985-05-08 |
2023-08-11 |
Not clear |
| R P Robertson, S A Littl. Down-regulation of prostaglandin E receptors and homologous desensitization of isolated adipocytes. Endocrinology. vol 113. issue 5. 1983-12-17. PMID:6138247. |
these studies were performed to ascertain whether pge binding sites in isolated adipocytes can be down-regulated and whether down-regulation (dr) decreases the sensitivity of the fat cell to the antilipolytic effects of pge2, adenosine, and insulin. |
1983-12-17 |
2023-08-12 |
rat |
| R P Robertson, S A Littl. Down-regulation of prostaglandin E receptors and homologous desensitization of isolated adipocytes. Endocrinology. vol 113. issue 5. 1983-12-17. PMID:6138247. |
in contrast, there was no desensitization of the adipocytes to the antilipolytic effects of phenylisopropyladenosine (ic50/control = 4.65 +/- 0.96 x 10(-10) m vs. dr = 4.90 +/- 0.82 x 10(-10) m; p = ns) or insulin (ic50/control = 4.40 +/- 0.57 x 10(-11) m vs. dr = 2.70 +/- 0.24 x 10(-11); p = ns). |
1983-12-17 |
2023-08-12 |
rat |
| C E Anderson, S E Hodge, R Rubin, J I Rotter, P I Terasaki, W J Irvine, D L Rimoi. A search for heterogeneity in insulin dependent diabetes mellitus (IDDM): HLA and autoimmune studies in simplex, multiplex and multigenerational families. Metabolism: clinical and experimental. vol 32. issue 5. 1983-06-10. PMID:6341762. |
hla antigens (a, b, c and dr loci), serum islet cell antibodies, thyrogastric antibodies, and insulin antibodies were studied in 77 families (25 simplex, 42 multiplex, and 10 multigenerational). |
1983-06-10 |
2023-08-12 |
Not clear |
| G Thomso. Investigation of the mode of inheritance of the HLA associated diseases by the method of antigen genotype frequencies among diseased individuals. Tissue antigens. vol 21. issue 2. 1983-06-10. PMID:6405504. |
dr data for insulin dependent diabetes mellitus (iddm) strongly indicate that there are two separate "disease" alleles, which exhibit negative complementation, predisposing individuals to iddm, where the mode of inheritance of the "disease" alleles considered separately is close to recessive. |
1983-06-10 |
2023-08-12 |
Not clear |
| J A Danilovs, F M Hofman, C R Taylor, J Brow. Expression of HLA-DR antigens in human fetal pancreas tissue. Diabetes. vol 31 Suppl 4. 1983-05-27. PMID:6762306. |
dual staining of dr antigens and insulin using a two-color immunoperoxidase technique clearly showed that some of these dr-positive dendritic cells were located within and in close association with insulin-producing islets. |
1983-05-27 |
2023-08-12 |
human |
| S Kontiaine. Human insulin specific suppressor factors. I. Induction, characteristics and comparison to murine factors. Clinical and experimental immunology. vol 47. issue 3. 1982-08-14. PMID:6211311. |
the insulin suppressor factors abolishing pork insulin specific helper cell activity were, like other human antigen specific suppressor factors described, antigen specific, carried ia-like (dr) determinants and the factor 'constant' region markers. |
1982-08-14 |
2023-08-12 |
mouse |
| J Barbosa, F H Bach, S S Ric. Genetic heterogeneity of diabetes and HLA. Clinical genetics. vol 21. issue 1. 1982-06-24. PMID:6950819. |
histocompatibility (hla) antigens and genotypes b, d and dr were studied in large sample of caucasian insulin dependent diabetic (idd) probands. |
1982-06-24 |
2023-08-12 |
Not clear |
| J Moriuchi, M Katagiri, A Wakisaka, N Matsuura, N Maruyama, H Ikeda, M Aizawa, K Itakur. Association of B cell alloantigen with juvenile onset diabetes mellitus in the Japanese. Human immunology. vol 1. issue 4. 1981-10-25. PMID:6973561. |
sixty-four japanese insulin dependent juvenile onset diabetes mellitus (jod) were studied in relation to hla-a, b, and dr. |
1981-10-25 |
2023-08-12 |
Not clear |
| W C Arnold, M A Hollida. Tissue resistance to insulin stimulation of amino acid uptake in acutely uremic rats. Kidney international. vol 16. issue 2. 1980-02-15. PMID:513501. |
the present study examined the effect of insulin on the uptake or distribution ratios (dr) of alpha-aminoisobutyric acid (aiba) attained in the tissues of rats made acutely uremic by bilateral nephrectomy. |
1980-02-15 |
2023-08-11 |
rat |
| W C Arnold, M A Hollida. Tissue resistance to insulin stimulation of amino acid uptake in acutely uremic rats. Kidney international. vol 16. issue 2. 1980-02-15. PMID:513501. |
both uremic and control rats concentrated equally aiba in the gastrocnemius muscle in the absence of insulin (dr = 2.82 +/- 0.39 in controls, 2.52 +/- 0.40 in uremics). |
1980-02-15 |
2023-08-11 |
rat |
| W C Arnold, M A Hollida. Tissue resistance to insulin stimulation of amino acid uptake in acutely uremic rats. Kidney international. vol 16. issue 2. 1980-02-15. PMID:513501. |
insulin had the expected effect of increasing the uptake in the gastrocnemius, diaphragm, and liver of control rats but had no effect on uptake in the gastrocnemius muscle of uremic rats (dr = 5.82 +/- 0.78 in controls, 3.07 +/- 0.60 in uremics). |
1980-02-15 |
2023-08-11 |
rat |