| Publication |
Sentence |
Publish Date |
Extraction Date |
Species |
| Hassan Tariq, Muhammad Rashid, Asfa Javed, Eeman Zafar, Saud S Alotaibi, Muhammad Yousuf Irfan Zi. Performance Analysis of Deep-Neural-Network-Based Automatic Diagnosis of Diabetic Retinopathy. Sensors (Basel, Switzerland). vol 22. issue 1. 2022-01-11. PMID:35009747. |
furthermore, in order to identify the severity of dr retina pictures, we use our own dataset to train deep convolutional neural networks (cnns). |
2022-01-11 |
2023-08-13 |
human |
| Janice X Ong, Amani A Fawz. Perspectives on diabetic retinopathy from advanced retinal vascular imaging. Eye (London, England). 2022-01-06. PMID:34987198. |
dr is associated with long-term chronic hyperglycaemia and its detrimental effects on the neurovascular structure and function of the retina. |
2022-01-06 |
2023-08-13 |
Not clear |
| Janice X Ong, Amani A Fawz. Perspectives on diabetic retinopathy from advanced retinal vascular imaging. Eye (London, England). 2022-01-06. PMID:34987198. |
direct imaging of the retinal vasculature and staging of dr has been traditionally based on fundoscopy and fluorescein angiography, which provide only 2d views of the retina, and in the case of fluorescein angiography, requires an invasive dye injection. |
2022-01-06 |
2023-08-13 |
Not clear |
| A Zh Fursova, A S Derbeneva, M V Vasilyeva, M S Tarasov, I F Nikulich, Yu A Gamz. [Structural and microvascular changes in the retina and choroid in patients with chronic kidney disease]. Vestnik oftalmologii. vol 137. issue 6. 2021-12-29. PMID:34965075. |
to study the main structural and microvascular changes in the retina and choroid in patients with diabetic retinopathy (dr) and chronic kidney disease (ckd), and their relationship with impaired renal function. |
2021-12-29 |
2023-08-13 |
Not clear |
| b' Hugo Ramos, Patricia Bogdanov, David Sabater, Jordi Huerta, Marta Valeri, Cristina Hern\\xc3\\xa1ndez, Rafael Sim\\xc3\\xb. Neuromodulation Induced by Sitagliptin: A New Strategy for Treating Diabetic Retinopathy. Biomedicines. vol 9. issue 12. 2021-12-24. PMID:34944588.' |
diabetic retinopathy (dr) involves progressive neurovascular degeneration of the retina. |
2021-12-24 |
2023-08-13 |
mouse |
| Shermaine W Y Low, Tanuja Vaidya, Santosh G K Gadde, Thirumalesh B Mochi, Devesh Kumar, Iris S Kassem, Deborah M Costakos, Baseer Ahmad, Swaminathan Sethu, Arkasubhra Ghosh, Shyam S Chaurasi. Decorin Concentrations in Aqueous Humor of Patients with Diabetic Retinopathy. Life (Basel, Switzerland). vol 11. issue 12. 2021-12-24. PMID:34947953. |
diabetic retinopathy (dr) is a microvascular complication of diabetes in the retina. |
2021-12-24 |
2023-08-13 |
human |
| Li Shan, Haiyong Zhang, Ying Han, Ruijuan Kuan. Expression and mechanism of microRNA 195 in diabetic retinopathy. Endocrine journal. 2021-12-23. PMID:34937832. |
mir-195 is overexpressed in dr, and its targeted relationship with sirt1 inhibits the growth of cells in the retina and accelerates apoptosis. |
2021-12-23 |
2023-08-13 |
human |
| Luis Mendes, Inês P Marques, José Cunha-Va. Comparison of Different Metrics for the Identification of Vascular Changes in Diabetic Retinopathy Using OCTA. Frontiers in neuroscience. vol 15. 2021-12-17. PMID:34916900. |
the best separation between the eyes with dr and the control group was obtained in the superficial capillary plexus (scp), with the full retina (fr) also performing well. |
2021-12-17 |
2023-08-13 |
Not clear |
| Eli Ip. Diabetic Retinopathy and Insulin Insufficiency: Beta Cell Replacement as a Strategy to Prevent Blindness. Frontiers in endocrinology. vol 12. 2021-12-16. PMID:34912295. |
the areas of evidence discussed are: (a) presence of insulin receptors in the retina, (b) clinical studies that show an association of beta cell insufficiency with dr, (c) treatment with insulin in type 2 diabetes, a marker for endogenous insulin deficiency, is an independent risk factor for dr, (d) recent clinical studies that link dr with an insulin deficient form of type 2 diabetes, and (e) beta cell replacement studies that demonstrate endogenous insulin prevents progression of dr. |
2021-12-16 |
2023-08-13 |
Not clear |
| David J Miller, M Ariel Cascio, Mariana G Rosc. Diabetic Retinopathy: The Role of Mitochondria in the Neural Retina and Microvascular Disease. Antioxidants (Basel, Switzerland). vol 9. issue 10. 2021-12-11. PMID:32977483. |
while its clinical diagnosis is based on vascular pathology, dr is associated with early abnormalities in the electroretinogram, indicating alterations of the neural retina and impaired visual signaling. |
2021-12-11 |
2023-08-13 |
Not clear |
| David J Miller, M Ariel Cascio, Mariana G Rosc. Diabetic Retinopathy: The Role of Mitochondria in the Neural Retina and Microvascular Disease. Antioxidants (Basel, Switzerland). vol 9. issue 10. 2021-12-11. PMID:32977483. |
there is evidence that microvascular disease in dr is caused in part by altered energetic metabolism in the neural retina and specifically from signals originating in the photoreceptors. |
2021-12-11 |
2023-08-13 |
Not clear |
| Gaganashree Shivashankar, Julie C Lim, Monica L Acost. Glyceraldehyde-3-phosphate dehydrogenase and glutamine synthetase inhibition in the presence of pro-inflammatory cytokines contribute to the metabolic imbalance of diabetic retinopathy. Experimental eye research. vol 213. 2021-12-08. PMID:34800480. |
although dr is clinically described as diabetes-induced damage to the retinal blood vessels, several studies have reported that metabolic dysregulation occurs in the retina prior to the development of microvascular damage. |
2021-12-08 |
2023-08-13 |
Not clear |
| Hannah J Nonarath, Alexandria E Hall, Gopika SenthilKumar, Betsy Abroe, Janis T Eells, Elizabeth S Liedhegne. 670nm photobiomodulation modulates bioenergetics and oxidative stress, in rat Müller cells challenged with high glucose. PloS one. vol 16. issue 12. 2021-12-07. PMID:34860856. |
muller glial cells, spanning the entirety of the retina, are involved in dr inflammation. |
2021-12-07 |
2023-08-13 |
rat |
| Jiayu Zhang, Chengwei Chen, Liang Wu, Qiang Wang, Jiawei Chen, Sifang Zhang, Zhenguo Che. Synoviolin inhibits inflammatory cytokine secretion of Müller cells by reducing NLRP3. Journal of molecular endocrinology. 2021-12-07. PMID:34874278. |
syvn1 was reduced and brcc3 was increased in dr retina and high glucose- (hg-) induced müller cells. |
2021-12-07 |
2023-08-13 |
mouse |
| Nikoo Bayan, Niloufar Yazdanpanah, Nima Rezae. Role of toll-like receptor 4 in diabetic retinopathy. Pharmacological research. 2021-12-06. PMID:34718133. |
while the detailed pathophysiology of dr is still unclear, increasing data suggests a crucial role for tlr4 in the development of dr. due to hyperglycemia, tlr4 expression increases in diabetic retina, which activates various pathways leading to dr. |
2021-12-06 |
2023-08-13 |
Not clear |
| R Pugal Priya, T S Sivarani, A Gnana Saravana. DEEP-LSTM BASED RED FOX OPTIMIZATION ALGORITHM FOR DIABETIC RETINOPATHY DETECTION AND CLASSIFICATION. International journal for numerical methods in biomedical engineering. 2021-12-05. PMID:34865312. |
because of retina abnormalities of diabetic patients, the most common vision-threatening disease is diabetic retinopathy (dr). |
2021-12-05 |
2023-08-13 |
Not clear |
| Gahyung Ryu, Kyungmin Lee, Donggeun Park, Sang Hyun Park, Min Sagon. A deep learning model for identifying diabetic retinopathy using optical coherence tomography angiography. Scientific reports. vol 11. issue 1. 2021-11-30. PMID:34837030. |
the results were similar regardless of the size and depth of the octa images, indicating that dr could be satisfactorily classified even with images comprising narrow area of the macular region and a single image slab of retina. |
2021-11-30 |
2023-08-13 |
human |
| Siddhi Dilip Chalke, Pravin Popatrao Kal. Combinational Approaches Targeting Neurodegeneration, Oxidative Stress, and Inflammation in the Treatment of Diabetic Retinopathy. Current drug targets. vol 22. issue 16. 2021-11-25. PMID:33745432. |
neurodegeneration, inflammation, and oxidative stress are the three important factors associated with the development of dr. oxidative stress is a major contributor to the onset and progression of dr. pathological events like retinal neurodegeneration and inflammation damage the retina in the early stages of dr. |
2021-11-25 |
2023-08-13 |
Not clear |
| Eimear M Byrne, María Llorián-Salvador, Timothy J Lyons, Mei Chen, Heping X. Tofacitinib Ameliorates Retinal Vascular Leakage in a Murine Model of Diabetic Retinopathy with Type 2 Diabetes. International journal of molecular sciences. vol 22. issue 21. 2021-11-18. PMID:34769307. |
pjak1 expression was also detected in human dr retina. |
2021-11-18 |
2023-08-13 |
mouse |
| Sayon Roy, Dongjoon Ki. Retinal capillary basement membrane thickening: Role in the pathogenesis of diabetic retinopathy. Progress in retinal and eye research. vol 82. 2021-11-17. PMID:32950677. |
dr develops over several years before clinical manifestations appear, and it is during this clinically silent period that hyperglycemia induces excess synthesis of bm components, contributes to vascular bm thickening, and promotes structural and functional lesions including cell death and vascular leakage in the diabetic retina. |
2021-11-17 |
2023-08-13 |
Not clear |