| Publication |
Sentence |
Publish Date |
Extraction Date |
Species |
| Jilai Shi, Li L. circKMT2E Protect Retina from Early Diabetic Retinopathy through SIRT1 Signaling Pathway via Sponging miR-204-5p. Computational and mathematical methods in medicine. vol 2022. 2022-10-14. PMID:36238483. |
to explore the changes of circrnas in the retina of diabetic patients without diabetic retinopathy (dr) to screen latent protective factor. |
2022-10-14 |
2023-08-14 |
Not clear |
| Pravin R Kshirsagar, Hariprasath Manoharan, Pratiksha Meshram, Jarallah Alqahtani, Quadri Noorulhasan Naveed, Saiful Islam, Tewodros Getinet Abeb. Recognition of Diabetic Retinopathy with Ground Truth Segmentation Using Fundus Images and Neural Network Algorithm. Computational intelligence and neuroscience. vol 2022. 2022-10-10. PMID:36211022. |
diabetes problems can lead to a condition called diabetic retinopathy (dr), which permanently damages the blood vessels in the retina. |
2022-10-10 |
2023-08-14 |
Not clear |
| Yufei Wang, Hongdan Yu, Jing Li, Wenqiang Liu, Shengxue Yu, Pan Lv, Lipan Zhao, Xiaobai Wang, Zhongfu Zuo, Xuezheng Li. Th22 cells induce Müller cell activation via the Act1/TRAF6 pathway in diabetic retinopathy. Cell and tissue research. 2022-10-06. PMID:36201050. |
all in all, the results suggested that th22 cells infiltrated into the retina and secreted il-22 in dr, and then il-22 binding with il-22rα1 activated the act1/traf6 signal pathway, and promoted the inflammatory of müller cells and involved the pathogenesis of dr. |
2022-10-06 |
2023-08-14 |
mouse |
| Michael O'Hare, Gema Esquiva, Mary K McGahon, Jose Manuel Romero Hombrebueno, Josy Augustine, Paul Canning, Kevin S Edgar, Peter Barabas, Thomas Friedel, Patrizia Cincolà, Jennifer Henry, Katie Mayne, Hannah Ferrin, Alan W Stitt, Timothy J Lyons, Derek P Brazil, David J Grieve, J Graham McGeown, Tim M Curti. Loss of TRPV2-mediated blood flow autoregulation recapitulates diabetic retinopathy in rats. JCI insight. vol 7. issue 18. 2022-09-22. PMID:36134661. |
we also demonstrate that trpv2 heterozygous rats, a nondiabetic model of impaired myogenic reactivity and blood flow autoregulation in the retina, develop a range of microvascular, glial, and neuronal lesions resembling those observed in dr, including neovascular complexes. |
2022-09-22 |
2023-08-14 |
human |
| Kangjia Lv, Hui Ying, Guangyi Hu, Jing Hu, Qizhi Jian, Fang Zhan. Integrated multi-omics reveals the activated retinal microglia with intracellular metabolic reprogramming contributes to inflammation in STZ-induced early diabetic retinopathy. Frontiers in immunology. vol 13. 2022-09-19. PMID:36119084. |
these findings suggest that activated microglia with intracellular metabolic reprogramming in retina may contribute to pro-inflammation in the early dr. |
2022-09-19 |
2023-08-14 |
mouse |
| Majed Alsaleh, Aishah H Alasmari, Abdullah S Y Al-Ame. Awareness of diabetic retinopathy among patients with type-2 diabetes mellitus in Abha, Saudi Arabia: A survey-based research study. Journal of family medicine and primary care. vol 11. issue 6. 2022-09-19. PMID:36119347. |
diabetic retinopathy (dr) is an avoidable retinal disorder affecting the retina and is deemed the most common microvascular complication of diabetes mellitus (dm). |
2022-09-19 |
2023-08-14 |
Not clear |
| Subhasish Pramanik, Kaustav Banerjee, Lakshmi Kanta Monda. The Amelioration of Detrimental Biochemical Anomalies by Supplementing B, C, and E Vitamins in Subjects with Type 2 Diabetes Mellitus May Reduce the Rate of Development of Diabetic Retinopathy. Journal of diabetes research. vol 2022. 2022-09-12. PMID:36090588. |
all these detrimental biochemical anomalies ultimately attack biological membranes and especially capillary beds of the retina, resulting in the breakdown of the inner blood-retinal barrier and the initiation of diabetic retinopathy (dr). |
2022-09-12 |
2023-08-14 |
human |
| Jannah Waled Hassan, Ashay D Bhatwadeka. Senolytics in the treatment of diabetic retinopathy. Frontiers in pharmacology. vol 13. 2022-09-12. PMID:36091769. |
senolytics are a new class of drugs that can selectively clear out senescent cells from the retina, thus holding a significant promise in dr treatment and prevention. |
2022-09-12 |
2023-08-14 |
Not clear |
| Mahmut Karakaya, Ramazan S Aygun, Ahmed B Salla. Collaborative Deep Learning for Privacy Preserving Diabetic Retinopathy Detection. Annual International Conference of the IEEE Engineering in Medicine and Biology Society. IEEE Engineering in Medicine and Biology Society. Annual International Conference. vol 2022. 2022-09-10. PMID:36086040. |
based on our experimental results on five different retina image datasets, dr detection accuracy is increased to 93.5% compared with the accuracies of merged datasets (84%) and individual datasets (73%, 78%, 83%, 85%). |
2022-09-10 |
2023-08-14 |
Not clear |
| Zahra Baharlouei, Hossein Rabbani, Gerlind Plonk. Detection of Retinal Abnormalities in OCT Images Using Wavelet Scattering Network. Annual International Conference of the IEEE Engineering in Medicine and Biology Society. IEEE Engineering in Medicine and Biology Society. Annual International Conference. vol 2022. 2022-09-10. PMID:36086219. |
in this paper, wavelet scattering network is used to identify normal retina and four pathologies namely, central serous retinopathy (csr), macular hole (mh), age-related macular degeneration (amd) and diabetic retinopathy (dr). |
2022-09-10 |
2023-08-14 |
Not clear |
| Zahra Baharlouei, Hossein Rabbani, Gerlind Plonk. Detection of Retinal Abnormalities in OCT Images Using Wavelet Scattering Network. Annual International Conference of the IEEE Engineering in Medicine and Biology Society. IEEE Engineering in Medicine and Biology Society. Annual International Conference. vol 2022. 2022-09-10. PMID:36086219. |
the results of this research show the accuracy of 97.4% and 100% in diagnosis abnormal retina and dr from normal ones, respectively. |
2022-09-10 |
2023-08-14 |
Not clear |
| Serena Mirra, Laura Sánchez-Bellver, Carmela Casale, Alessandra Pescatore, Gemma Marfan. Ubiquitin Specific Protease USP48 Destabilizes NF-κB/p65 in Retinal Pigment Epithelium Cells. International journal of molecular sciences. vol 23. issue 17. 2022-09-09. PMID:36077078. |
in the retina, the modulation of the nf-κb pathway is essential to prevent excessive inflammatory responses, which plays a pivotal role in many retinal neurodegenerative diseases, such as age-related macular degeneration (amd), diabetic retinopathy (dr), and inherited retinal dystrophies (irds). |
2022-09-09 |
2023-08-14 |
Not clear |
| Victoria Maneu, Pedro Lax, Antonio Miguel G De Diego, Nicolás Cuenca, Antonio G Garcí. Combined drug triads for synergic neuroprotection in retinal degeneration. Biomedicine & pharmacotherapy = Biomedecine & pharmacotherapie. vol 149. 2022-09-07. PMID:36068774. |
this review focuses on retina degeneration occurring during glaucoma, age-related macular degeneration (amd), diabetic retinopathy (dr), and retinitis pigmentosa (rp), and on the potential therapeutic use of triads of repositioned medicines, addressed to distinct but complementary targets, to prevent, delay or stop retina cell death. |
2022-09-07 |
2023-08-14 |
Not clear |
| Ahmed Mohamud Yusuf, Rebecca Claire Lusobya, John Mukisa, Charles Batte, Damalie Nakanjako, Otiti Juliet-Senger. Validity of smartphone-based retinal photography (PEEK-retina) compared to the standard ophthalmic fundus camera in diagnosing diabetic retinopathy in Uganda: A cross-sectional study. PloS one. vol 17. issue 9. 2022-09-06. PMID:36067194. |
the study aimed to determine the sensitivity and specificity of the portable eye examination kit (peek) retina compared to a standard ophthalmic fundus camera (zeiss visucam 200) for the diagnosis of dr. |
2022-09-06 |
2023-08-14 |
Not clear |
| Tingyu Qin, Xiangying Xi, Zhipeng W. Downregulation of glycoprotein non-metastatic melanoma protein B prevents high glucose-induced angiogenesis in diabetic retinopathy. Molecular and cellular biochemistry. 2022-08-29. PMID:36036335. |
additionally, increased gpnmb levels were detected in the retina of dr rats induced by a single intraperitoneal injection of streptozotocin (60 mg/kg) using real-time pcr, western blot, and immunofluorescence assays. |
2022-08-29 |
2023-08-14 |
human |
| Tingyu Qin, Xiangying Xi, Zhipeng W. Downregulation of glycoprotein non-metastatic melanoma protein B prevents high glucose-induced angiogenesis in diabetic retinopathy. Molecular and cellular biochemistry. 2022-08-29. PMID:36036335. |
downregulation of gpnmb inhibited the angiogenesis and vascular endothelial growth factor production in the retina of rats with dr. |
2022-08-29 |
2023-08-14 |
human |
| Chaoqun Liu, Yue Ren, Xin Sui, Kaiyang Liu, Jianing Zhang, Zian Wang, Yingying Li, Yanling Zhan. Integrating network pharmacology, transcriptomics, and molecular simulation to reveal the mechanism of tert-butylhydroquinone for treating diabetic retinopathy. European journal of pharmacology. 2022-08-20. PMID:35987258. |
as one of the crucial factors in the pathogenesis of dr, oxidative stress provides new insights for the treatment of dr. tert-butylhydroquinone (tbhq), an efficient phenolic antioxidant, has been proved to inhibit diabetic retina injury. |
2022-08-20 |
2023-08-14 |
Not clear |
| Jing Huang, Qiong Zho. CD8+T Cell-Related Gene Biomarkers in Macular Edema of Diabetic Retinopathy. Frontiers in endocrinology. vol 13. 2022-08-08. PMID:35937822. |
however, the infiltration of cd8+t cells in the dr retina, especially in diabetic macular edema (dme), and its related genes are still unclear. |
2022-08-08 |
2023-08-14 |
Not clear |
| Hua-Qin Xia, Jia-Rui Yang, Ke-Xin Zhang, Rui-Lan Dong, Hao Yuan, Yu-Chen Wang, Hong Zhou, Xue-Min L. Molecules related to diabetic retinopathy in the vitreous and involved pathways. International journal of ophthalmology. vol 15. issue 7. 2022-08-03. PMID:35919310. |
the vitreous takes up 80% of the whole globe volume and is in direct contact with the retina, making it possible to explore the pathogenesis of dr by studying related factors in the vitreous. |
2022-08-03 |
2023-08-14 |
Not clear |
| Dalia I Aldosari, Ajamaluddin Malik, Abdullah S Alhomida, Mohammad S Ol. Implications of Diabetes-Induced Altered Metabolites on Retinal Neurodegeneration. Frontiers in neuroscience. vol 16. 2022-08-01. PMID:35911994. |
this implies understanding the pathophysiological mechanisms at the early stage of disease progression especially due to diabetes-induced metabolic alterations to damage the neural retina so that early intervention and treatments options can be identified to prevent and inhibit the progression of dr. hyperglycemia has been widely considered the major contributor to the progression of the retinal damage, even though tight control of glucose does not seem to have a bigger effect on the incidence or progression of retinal damage that leads to dr. |
2022-08-01 |
2023-08-14 |
Not clear |