Publication |
Sentence |
Publish Date |
Extraction Date |
Species |
Burak Mugdat Karan, Karis Little, Josy Augustine, Alan W Stitt, Tim M Curti. Aldehyde Dehydrogenase and Aldo-Keto Reductase Enzymes: Basic Concepts and Emerging Roles in Diabetic Retinopathy. Antioxidants (Basel, Switzerland). vol 12. issue 7. 2023-07-29. PMID:37508004. |
it also provides an overview of the aldh and akr enzymes expressed in the retina, emphasizing their growing importance in dr. understanding the relationship between aldehyde metabolism and dr could guide innovative therapeutic strategies to protect the retina and preserve vision in diabetic patients. |
2023-07-29 |
2023-08-14 |
Not clear |
Gokul Sudhakaran, Abhirami Chandran, A R Sreekutty, S Madesh, Raman Pachaiappan, Bader O Almutairi, Selvaraj Arokiyaraj, Zulhisyam Abdul Kari, Guillermo Tellez-Isaias, Ajay Guru, Jesu Arockiara. Ophthalmic Intervention of Naringenin Decreases Vascular Endothelial Growth Factor by Counteracting Oxidative Stress and Cellular Damage in In Vivo Zebrafish. Molecules (Basel, Switzerland). vol 28. issue 14. 2023-07-29. PMID:37513223. |
ng regressed the glucose levels and cellular damage along with an inhibition of macular degeneration in the retina of adult zebrafish and normalized the overexpression of vegf as a promising strategy for treating dr. |
2023-07-29 |
2023-08-14 |
zebrafish |
Agata Grazia D'Amico, Grazia Maugeri, Benedetta Magrì, Claudia Lombardo, Salvatore Saccone, Concetta Federico, Paola Cavallaro, Salvatore Giunta, Claudio Bucolo, Velia D'Agat. PACAP-ADNP AXIS PREVENTS OUTER RETINAL BARRIER BREAKDOWN AND CHOROIDAL NEOVASCULARIZATION BY INTERFERING WITH VEGF SECRETED FROM RETINAL PIGMENTED EPITELIUM CELLS. Peptides. 2023-07-26. PMID:37495040. |
during diabetic retinopathy (dr) progression, the retina undergoes various metabolic changes, including hypoxia-signalling cascade induction in the cells of retinal pigmented epithelium (rpe). |
2023-07-26 |
2023-08-14 |
Not clear |
Anna Bryl, Małgorzata Mrugacz, Mariusz Falkowski, Katarzyna Zoren. A Mediterranean Diet May Be Protective in the Development of Diabetic Retinopathy. International journal of molecular sciences. vol 24. issue 13. 2023-07-14. PMID:37446322. |
resveratrol can inhibit increased vascular leakage and loss of pericytes and regulate the level of vegf protein in the retina, thus inhibiting the development of dr. |
2023-07-14 |
2023-08-14 |
Not clear |
S V Hemanth, Saravanan Alagarsamy, T Dhiliphan Rajkuma. Convolutional neural network-based sea lion optimization algorithm for the detection and classification of diabetic retinopathy. Acta diabetologica. 2023-06-27. PMID:37368025. |
diabetic retinopathy (dr) becomes a complicated type of diabetic that causes damage to the blood vessels of the retina's light-sensitive tissue. |
2023-06-27 |
2023-08-14 |
Not clear |
Haitao Liu, Sayan Ghosh, Tanuja Vaidya, Sridhar Bammidi, Chao Huang, Peng Shang, Archana Padmanabhan Nair, Olivia Chowdhury, Nadezda A Stepicheva, Anastasia Strizhakova, Stacey Hose, Nikolaos Mitrousis, Santosh Gopikrishna Gadde, Thirumalesh Mb, Pamela Strassburger, Gabriella Widmer, Eleonora M Lad, Patrice E Fort, José-Alain Sahel, J Samuel Zigler, Swaminathan Sethu, Peter D Westenskow, Alan D Proia, Akrit Sodhi, Arkasubhra Ghosh, Derrick Feenstra, Debasish Sinh. Activated cGAS/STING signaling elicits endothelial cell senescence in early diabetic retinopathy. JCI insight. vol 8. issue 12. 2023-06-22. PMID:37345657. |
sting has been previously shown to regulate cell senescence and inflammation, key contributors to the development and progression of dr. to investigate the mechanism whereby sting contributes to the pathogenesis of dr, diabetes was induced in sting-ko mice and stinggt (loss-of-function mutation) mice, and molecular alterations and pathological changes in the retina were characterized. |
2023-06-22 |
2023-08-14 |
mouse |
Jacob J Aiello, Maislin C Bogart, Wai-Ting Chan, Nicholas C Holoman, Timothy D Trobenter, Chloe E Relf, Dana M Kleinman, Darryl C De Vivo, Ivy S Samuel. Systemic Reduction of Glut1 Normalizes Retinal Dysfunction, Inflammation, and Oxidative Stress in the Retina of Spontaneous Type 2 Diabetic Mice. The American journal of pathology. vol 193. issue 7. 2023-06-19. PMID:37062410. |
defects in the light-evoked responses of the retina occur early in the sequalae of diabetic retinopathy (dr). |
2023-06-19 |
2023-11-20 |
mouse |
Ricardo Lamy, Showgy Ma'ayeh, Sarantis Chlamydas, Jay M Stewar. Proximity Extension Assay (PEA) Platform to Detect Vitreous Biomarkers of Diabetic Retinopathy. Methods in molecular biology (Clifton, N.J.). vol 2678. 2023-06-16. PMID:37326709. |
the use of molecular biology to discover biomarkers of dr has great potential to impact the standard of care, and the vitreous humor can serve as an indirect source for those molecular biomarkers because it is rich in proteins secreted by the retina. |
2023-06-16 |
2023-08-14 |
Not clear |
Zahid Ullah, Muhammad Usman, Siddique Latif, Asifullah Khan, Jeonghwan Gwa. SSMD-UNet: semi-supervised multi-task decoders network for diabetic retinopathy segmentation. Scientific reports. vol 13. issue 1. 2023-06-05. PMID:37277554. |
diabetic retinopathy (dr) is a diabetes complication that can cause vision loss among patients due to damage to blood vessels in the retina. |
2023-06-05 |
2023-08-14 |
Not clear |
Zhipeng Li, Hongli Yu, Chaolong Liu, Changduo Wang, Xianhu Zeng, Jianqin Yan, Yong Su. Efficiency co-delivery of ellagic acid and oxygen by a non-invasive liposome for ameliorating diabetic retinopathy. International journal of pharmaceutics. 2023-05-19. PMID:37207860. |
significantly, after being administered as an injection or eye drops, ea-hb/tat&isodgr-lipo obviously ameliorated the structure (central retinal thickness and retinal vascular network) of retina by eliminating ros and down-regulating the expression of gfap, hif-1α, vegf and p-vegfr2 in a dr mouse model. |
2023-05-19 |
2023-08-14 |
mouse |
Erika D Egger. Visual Dysfunction in Diabetes. Annual review of vision science. 2023-05-10. PMID:37164027. |
prior to the onset of dr, human patients have compromised electroretinograms that indicate a disruption of normal function, particularly in the inner retina. |
2023-05-10 |
2023-08-14 |
human |
Semra Koca, Esra Vural, Ender Sırakaya, Deniz Kılı. Evaluation of the lamina cribrosa in different stages of diabetic retinopathy. Japanese journal of ophthalmology. 2023-04-11. PMID:37039947. |
to evaluate the relationship of the peripapillary retina nerve fiber layer (rnfl) and lamina cribrosa (lc) with diabetic retinopathy (dr) in type 2 diabetes mellitus (dm) cases. |
2023-04-11 |
2023-08-14 |
Not clear |
Veeresh Toragall, J C Muzaffar, Vallikanan Baskara. Lutein loaded double-layered polymer nanocarrier modulate H International journal of biological macromolecules. 2023-04-08. PMID:37030468. |
lutein loaded double-layered polymer nanocarrier modulate h lutein plays a crucial role in the protection of retina by diminishing oxidative stress in diabetic retinopathy (dr). |
2023-04-08 |
2023-08-14 |
Not clear |
Veeresh Toragall, J C Muzaffar, Vallikanan Baskara. Lutein loaded double-layered polymer nanocarrier modulate H International journal of biological macromolecules. 2023-04-08. PMID:37030468. |
also, beneficial effects of lutein supplementation and lower lutein levels in the serum and retina of dr patients created an interest in nanopreparation. |
2023-04-08 |
2023-08-14 |
Not clear |
Anton M Kolomeyer, David A Eichenbaum, Daniel F Kiernan, Ivan J Suñer, Seenu M Hariprasa. The 0.19-mg Fluocinolone Acetonide Implant for the Treatment of Diabetic Macular Edema: An Expert Consensus. Ophthalmic surgery, lasers & imaging retina. vol 54. issue 3. 2023-03-21. PMID:36944067. |
to better understand the level of agreement among retina specialists on the role of inflammation in diabetic retinopathy (dr) and diabetic macular edema (dme), and the use of 0.19-mg fluocinolone acetonide (fac) implant in dme treatment, a consensus survey was drafted and disseminated to retina specialists across the united states. |
2023-03-21 |
2023-08-14 |
Not clear |
Benjamin Ho. High-fidelity diabetic retina fundus image synthesis from freestyle lesion maps. Biomedical optics express. vol 14. issue 2. 2023-03-06. PMID:36874499. |
retina fundus imaging for diagnosing diabetic retinopathy (dr) is an efficient and patient-friendly modality, where many high-resolution images can be easily obtained for accurate diagnosis. |
2023-03-06 |
2023-08-14 |
human |
Xiongyi Yang, Zexin Huang, Mei Xu, Yanxia Chen, Mingzhe Cao, Guoguo Yi, Min F. Autophagy in the retinal neurovascular unit: New perspectives into diabetic retinopathy. Journal of diabetes. 2023-03-02. PMID:36864557. |
we discuss the strong association between dr and autophagy in this review, as well as the many kinds of autophagy and its crucial physiological activities in the retina. |
2023-03-02 |
2023-08-14 |
Not clear |
Midhula Vijayan, Venkatakrishnan . A Regression-Based Approach to Diabetic Retinopathy Diagnosis Using Efficientnet. Diagnostics (Basel, Switzerland). vol 13. issue 4. 2023-02-25. PMID:36832262. |
the aim of this study is to develop a computer-assisted solution for the efficient and effective detection of diabetic retinopathy (dr), a complication of diabetes that can damage the retina and cause vision loss if not treated in a timely manner. |
2023-02-25 |
2023-08-14 |
Not clear |
Maryam Monemian, Hossein Rabban. Exudate identification in retinal fundus images using precise textural verifications. Scientific reports. vol 13. issue 1. 2023-02-22. PMID:36808177. |
one of the most salient diseases of retina is diabetic retinopathy (dr) which may lead to irreparable damages to eye vision in the advanced phases. |
2023-02-22 |
2023-08-14 |
Not clear |
Awais Bajwa, Neelam Nosheen, Khalid Iqbal Talpur, Sheeraz Akra. A Prospective Study on Diabetic Retinopathy Detection Based on Modify Convolutional Neural Network Using Fundus Images at Sindh Institute of Ophthalmology & Visual Sciences. Diagnostics (Basel, Switzerland). vol 13. issue 3. 2023-02-11. PMID:36766498. |
diabetic retinopathy (dr) is the most common complication that arises due to diabetes, and it affects the retina. |
2023-02-11 |
2023-08-14 |
Not clear |