Publication |
Sentence |
Publish Date |
Extraction Date |
Species |
K Pradeep, Vijay Jeyakumar, Muna Bhende, Areeba Shakeel, Shriraam Mahadeva. Artificial intelligence and hemodynamic studies in optical coherence tomography angiography for diabetic retinopathy evaluation: A review. Proceedings of the Institution of Mechanical Engineers. Part H, Journal of engineering in medicine. 2023-12-04. PMID:38044619. |
diabetic retinopathy (dr) is a rapidly emerging retinal abnormality worldwide, which can cause significant vision loss by disrupting the vascular structure in the retina. |
2023-12-04 |
2023-12-10 |
Not clear |
K Pradeep, Vijay Jeyakumar, Muna Bhende, Areeba Shakeel, Shriraam Mahadeva. Artificial intelligence and hemodynamic studies in optical coherence tomography angiography for diabetic retinopathy evaluation: A review. Proceedings of the Institution of Mechanical Engineers. Part H, Journal of engineering in medicine. 2023-12-04. PMID:38044619. |
quantitative indicators obtained from octa, such as blood vessel segmentation of the retina, foveal avascular zone (faz) extraction, retinal blood vessel density, blood velocity, flow rate, capillary vessel pressure, and retinal oxygen extraction, have been identified as crucial hemodynamic features for screening dr using computer-aided systems in artificial intelligence (ai). |
2023-12-04 |
2023-12-10 |
Not clear |
Li Chen, En Qi, Xuan Liu, Lijun Cui, Xiaojuan Fan, Ting Wei, Yaguang H. The lack of homology domain and leucine rich repeat protein phosphatase 2 ameliorates visual impairment in rats with diabetic retinopathy through regulation of the AKT-GSK-3β-Nrf2 signal cascade. Toxicology and applied pharmacology. 2023-11-23. PMID:37995808. |
decreasing the expression of phlpp2 ameliorated visual function impairment and improved the pathological changes of retina in dr rats. |
2023-11-23 |
2023-11-29 |
rat |
Li Chen, En Qi, Xuan Liu, Lijun Cui, Xiaojuan Fan, Ting Wei, Yaguang H. The lack of homology domain and leucine rich repeat protein phosphatase 2 ameliorates visual impairment in rats with diabetic retinopathy through regulation of the AKT-GSK-3β-Nrf2 signal cascade. Toxicology and applied pharmacology. 2023-11-23. PMID:37995808. |
these observations show that the down-regulation of phlpp2 has protective effects on dr by preserving the structure and function of the retina by regulating the akt-gsk-3β-nrf2 signal cascade. |
2023-11-23 |
2023-11-29 |
rat |
Saket Y Maheshwari, Sunil Kumar, Arya Harshyt Sinha, Mayank Kuma. Diabetic Retinopathy: A Pharmacological Consideration. Cureus. vol 15. issue 10. 2023-11-13. PMID:37954772. |
a major stumbling block that diabetes creates in the healthy living of any of its sufferers is a complication called diabetic retinopathy (dr), which, in its most elementary and perspicuous form, refers to damage to the blood vessels in the retina of the human eye that occurs as a result of high serum glucose levels. |
2023-11-13 |
2023-11-20 |
human |
Sharadha Madhusudhan, Naresh Vishal Gupta, Mohamed Rahamathulla, Saravana Babu Chidambaram, Riyaz Ali M Osmani, Mohammed Ghazwani, Mohammed Muqtader Ahmed, Syeda Ayesha Farhana, Mohammed Y Sarhan, Ahmed Hediyal Tousi. Subconjunctival Delivery of Sorafenib-Tosylate-Loaded Cubosomes for Facilitated Diabetic Retinopathy Treatment: Formulation Development, Evaluation, Pharmacokinetic and Pharmacodynamic (PKPD) Studies. Pharmaceutics. vol 15. issue 10. 2023-10-30. PMID:37896180. |
the study outcomes established that the developed nanocarriers were ideal for delivering the st-cubs via the scj route to target the retina for facilitated dr management. |
2023-10-30 |
2023-11-08 |
rat |
Rosario Amato, Alberto Melecchi, Laura Pucci, Alessio Canovai, Silvia Marracci, Maurizio Cammalleri, Massimo Dal Monte, Carla Caddeo, Giovanni Casin. Liposome-Mediated Delivery Improves the Efficacy of Lisosan G against Retinopathy in Diabetic Mice. Cells. vol 12. issue 20. 2023-10-27. PMID:37887292. |
lisosan g (lg), a fermented powder from whole grains, protects the retina from diabetic retinopathy (dr)-induced damage. |
2023-10-27 |
2023-11-08 |
mouse |
Mohammed Arif Iftakher Mahmood, Nasrin Aktar, Md Fazlul Kade. A hybrid approach for diagnosing diabetic retinopathy from fundus image exploiting deep features. Heliyon. vol 9. issue 9. 2023-10-09. PMID:37809795. |
microaneurysms and hemorrhages that appear in the retina are the early signs of dr. |
2023-10-09 |
2023-10-15 |
human |
LinHui Yuan, LiJun Zhang, Xin Liu, Sheng Li, JiXin Zo. Identification of differential immune cells and related diagnostic genes in patients with diabetic retinopathy. Medicine. vol 102. issue 39. 2023-09-29. PMID:37773794. |
therefore, this investigation screens immune-associated biomarkers in the retina of dr patients. |
2023-09-29 |
2023-10-07 |
Not clear |
Rui Wang, Qiu-Yuan Wang, Yang Bai, Ye-Ge Bi, Shan-Jun Ca. Research progress of diabetic retinopathy and gut microecology. Frontiers in microbiology. vol 14. 2023-09-25. PMID:37744925. |
substantial research has highlighted that microangiopathy and chronic low-grade inflammation are widespread in the retina of dr. |
2023-09-25 |
2023-10-07 |
Not clear |
Hui You, Hongyu Li, Wenjun Go. lncRNA HOTAIR promotes ROS generation and NLRP3 inflammasome activation by inhibiting Nrf2 in diabetic retinopathy. Medicine. vol 102. issue 37. 2023-09-15. PMID:37713847. |
diabetic retinopathy (dr) is a microvascular complication associated with damage to the retina due to inflammation induced by high glucose. |
2023-09-15 |
2023-10-07 |
Not clear |
Christopher R Starr, Assylbek Zhylkibayev, James A Mobley, Marina S Gorbatyu. Proteomic analysis of diabetic retinas. Frontiers in endocrinology. vol 14. 2023-09-11. PMID:37693346. |
the mechanism of dr is complex and known to impact both neural and vascular components in the retina. |
2023-09-11 |
2023-10-07 |
Not clear |
Christopher R Starr, Assylbek Zhylkibayev, James A Mobley, Marina S Gorbatyu. Proteomic analysis of diabetic retinas. Frontiers in endocrinology. vol 14. 2023-09-11. PMID:37693346. |
while recent advances in the field have identified major cellular signaling contributing to dr pathogenesis, little has been reported on the protein post-translational modifications (ptm) - known to define protein localization, function, and activity - in the diabetic retina overall. |
2023-09-11 |
2023-10-07 |
Not clear |
Dewei Yi, Petar Baltov, Yining Hua, Sam Philip, Pradip Kumar Sharm. Compound Scaling Encoder-Decoder (CoSED) Network for Diabetic Retinopathy Related Bio-marker Detection. IEEE journal of biomedical and health informatics. vol PP. 2023-09-11. PMID:37695962. |
dr is an ocular disease that affects the retina in people with diabetes and could lead to visual impairment if management measures are not taken in a timely manner. |
2023-09-11 |
2023-10-07 |
Not clear |
Mohammed Alshahrani, Mohammed Al-Jabbar, Ebrahim Mohammed Senan, Ibrahim Abdulrab Ahmed, Jamil Abdulhamid Mohammed Sai. Hybrid Methods for Fundus Image Analysis for Diagnosis of Diabetic Retinopathy Development Stages Based on Fusion Features. Diagnostics (Basel, Switzerland). vol 13. issue 17. 2023-09-09. PMID:37685321. |
diabetic retinopathy (dr) is a complication of diabetes that damages the delicate blood vessels of the retina and leads to blindness. |
2023-09-09 |
2023-10-07 |
Not clear |
Gamze Gizem Erayman, Selma Urfalıoglu, Gökhan Ozdemi. Evaluation of Posterior Ocular Blood Flow in Diabetic Retinopathy Patients Without Macular Edema Using Optical Coherence Tomography Angiography. Photodiagnosis and photodynamic therapy. 2023-09-05. PMID:37669724. |
the objective of this study is to investigate and compare the superficial and deep vascular structures of the retina, as well as the changes in the choriocapillaris (cc) and optic disc microvasculature, using optical coherence tomography angiography (octa) in patients diagnosed with diabetes mellitus (dm) without diabetic retinopathy (dr), patients with non-proliferative and proliferative dr, and healthy individuals. |
2023-09-05 |
2023-10-07 |
Not clear |
Toshiyuki Oshitar. Neurovascular Cell Death and Therapeutic Strategies for Diabetic Retinopathy. International journal of molecular sciences. vol 24. issue 16. 2023-08-26. PMID:37629100. |
dr was recently defined as a neurovascular disease associated with tissue-specific neurovascular impairment of the retina in patients with diabetes. |
2023-08-26 |
2023-09-07 |
Not clear |
Amy D Stockwell, Michael C Chang, Anubha Mahajan, William Forrest, Neha Anegondi, Rion K Pendergrass, Suresh Selvaraj, Jens Reeder, Eric Wei, V A Iglesias, Natalie M Creps, Laura Macri, Andrea N Neeranjan, Marcel P van der Brug, Suzie J Scales, Mark I McCarthy, Brian L Yaspa. Multi-ancestry GWAS analysis identifies two novel loci associated with diabetic eye disease and highlights APOL1 as a high risk locus in patients with diabetic macular edema. PLoS genetics. vol 19. issue 8. 2023-08-16. PMID:37585454. |
approximately 20% of dr patients have diabetic macular edema (dme) characterized by fluid leakage into the retina. |
2023-08-16 |
2023-09-07 |
Not clear |
Huade Mai, Chenghong Liu, Biwei Fu, Xinbo Ji, Minghui Chen, Yunbo Zhang, Yunyun Lin, Juming Chen, Yanling Song, Shenhong G. Methylene Blue Reduces Retinal Cell Inflammation, Apoptosis, and Oxidative Stress in a Rat Model of Diabetic Retinopathy via Sirtuin 1 Activation. Alternative therapies in health and medicine. 2023-08-03. PMID:37535922. |
diabetic retinopathy (dr), characterized by neuronal damage in the retina, is primarily driven by oxidative stress resulting from diabetes (dm). |
2023-08-03 |
2023-08-14 |
rat |
Janani Surya, Garima, Neha Pandy, Tyler Hyungtaek Rim, Geunyoung Lee, M N Swathi Priya, Brughanya Subramanian, Rajiv Rama. Efficacy of deep learning-based artificial intelligence models in screening and referring patients with diabetic retinopathy and glaucoma. Indian journal of ophthalmology. vol 71. issue 8. 2023-08-02. PMID:37530278. |
to analyze the efficacy of a deep learning (dl)-based artificial intelligence (ai)-based algorithm in detecting the presence of diabetic retinopathy (dr) and glaucoma suspect as compared to the diagnosis by specialists secondarily to explore whether the use of this algorithm can reduce the cross-referral in three clinical settings: a diabetologist clinic, retina clinic, and glaucoma clinic. |
2023-08-02 |
2023-08-14 |
Not clear |