| Publication |
Sentence |
Publish Date |
Extraction Date |
Species |
| Yongjian Huang, Chaoxu Qian, Jilin Zhou, Jinsong Xu. Investigation of expression and influence of CTGF and HO-1 in rats with diabetic retinopathy. Experimental and therapeutic medicine. vol 19. issue 3. 2020-09-28. PMID:32104296. |
the retinal apoptosis rate of dr rats gradually increased at the 2nd, 4th and 6th month, after which, the ctgf expression gradually increased, but the ho-1 expression gradually decreased in retina in the dr group. |
2020-09-28 |
2023-08-13 |
rat |
| Rajini Nagaraj, Trevor Stack, Sijia Yi, Benjamin Mathew, Kenneth R Shull, Evan A Scott, Mathew T Mathew, Divya Rani Bijukuma. High Density Display of an Anti-Angiogenic Peptide on Micelle Surfaces Enhances Their Inhibition of αvβ3 Integrin-Mediated Neovascularization In Vitro. Nanomaterials (Basel, Switzerland). vol 10. issue 3. 2020-09-28. PMID:32235802. |
diabetic retinopathy (dr), retinopathy of pre-maturity (rop), and age-related macular degeneration (amd) are multifactorial manifestations associated with abnormal growth of blood vessels in the retina. |
2020-09-28 |
2023-08-13 |
Not clear |
| Oluwatobi Noah Akande, Oluwakemi Christiana Abikoye, Aderonke Anthonia Kayode, Yema Lamar. Implementation of a Framework for Healthy and Diabetic Retinopathy Retinal Image Recognition. Scientifica. vol 2020. 2020-09-28. PMID:32509373. |
however, literature has shown that certain eye diseases such as diabetic retinopathy (dr), hypertensive retinopathy, glaucoma, and cataract could alter the recognition accuracy of the retina recognition system. |
2020-09-28 |
2023-08-13 |
Not clear |
| Atheer Alhumud, Fadwa Al Adel, Manal Alwazae, Ghadeer Althaqib, Atheer Almutair. Patient Satisfaction Toward a Tele-Retinal Screening Program in Endocrinology Clinics at a Tertiary Hospital in Riyadh, Saudi Arabia. Cureus. vol 12. issue 5. 2020-09-28. PMID:32523842. |
some 23.9% did not like the idea of only seeing the ophthalmologist when it is necessary and only 9.8% had some doubts of the doctor's ability to diagnose dr by evaluating retina photos only. |
2020-09-28 |
2023-08-13 |
human |
| Heiner Kremer, Julian Gebauer, Susanne Elvers-Hornung, Stefanie Uhlig, Hans-Peter Hammes, Elena Beltramo, Lothar Steeb, Martin C Harmsen, Carsten Sticht, Harald Klueter, Karen Bieback, Agnese Fior. Pro-angiogenic Activity Discriminates Human Adipose-Derived Stromal Cells From Retinal Pericytes: Considerations for Cell-Based Therapy of Diabetic Retinopathy. Frontiers in cell and developmental biology. vol 8. 2020-09-28. PMID:32582693. |
in models of dr, asc not only generated a cytoprotective and reparative environment by the secretion of trophic factors but also engrafted and integrated into the retina in a pericyte-like fashion. |
2020-09-28 |
2023-08-13 |
human |
| D V Petrachkov, M V Budzinskaya, K V Baryshe. [Current possibilities in visualization of retinal periphery in diabetic retinopathy]. Vestnik oftalmologii. vol 136. issue 4. Vyp. 2. 2020-09-04. PMID:32880150. |
the article contains detailed examination of the modern widefield imaging methods that allow studying the middle and extreme periphery of the retina and help obtain a wide range of dr biomarkers. |
2020-09-04 |
2023-08-13 |
Not clear |
| V G Pavlov, A L Sidamonidze, D V Petrachko. [Current trends in the screening for diabetic retinopathy]. Vestnik oftalmologii. vol 136. issue 4. Vyp. 2. 2020-09-04. PMID:32880155. |
various research methods are described, such as fluorescence angiography, optical coherence tomography, optical coherence tomography agniography, laser scanning ophthalmoscopy, which can be used to visualize pathological changes in the retina associated with dr. |
2020-09-04 |
2023-08-13 |
Not clear |
| A Aouiss, D Anka Idrissi, M Kabine, Y Zai. Update of inflammatory proliferative retinopathy: Ischemia, hypoxia and angiogenesis. Current research in translational medicine. vol 67. issue 2. 2020-08-28. PMID:30685380. |
diabetic retinopathy (dr) and retinopathy of prematurity (rop) present two examples of proliferative retinopathy, characterized by the same stages of progression; ischemia of the retinal vessels, leads to hypoxia and to correct the problem there is the setting up of uncontrolled angiogenesis, which subsequently causes blindness or even detachment of the retina. |
2020-08-28 |
2023-08-13 |
Not clear |
| A Aouiss, D Anka Idrissi, M Kabine, Y Zai. Update of inflammatory proliferative retinopathy: Ischemia, hypoxia and angiogenesis. Current research in translational medicine. vol 67. issue 2. 2020-08-28. PMID:30685380. |
the difference is the following; that dr initiated by the metabolic complications that are due to hyperglycemia, and rop is induced by overexposure of the neonatal retina to oxygen. |
2020-08-28 |
2023-08-13 |
Not clear |
| A Aouiss, D Anka Idrissi, M Kabine, Y Zai. Update of inflammatory proliferative retinopathy: Ischemia, hypoxia and angiogenesis. Current research in translational medicine. vol 67. issue 2. 2020-08-28. PMID:30685380. |
in this review, we will demonstrate the physiopathological mechanism of the two forms of proliferative retinopathy dr and rop, in particular the role of the cd40/cd40l axis and il-1 on vascular complications and onset of inflammation of the retina, the implications of their effects on the onset of pathogenic angiogenesis, thus understanding the link between platelets and retinal ischemia. |
2020-08-28 |
2023-08-13 |
Not clear |
| Mahmut Karakaya, Recep E Hacisoftaogl. Comparison of smartphone-based retinal imaging systems for diabetic retinopathy detection using deep learning. BMC bioinformatics. vol 21. issue Suppl 4. 2020-08-11. PMID:32631221. |
diabetic retinopathy (dr), the most common cause of vision loss, is caused by damage to the small blood vessels in the retina. |
2020-08-11 |
2023-08-13 |
Not clear |
| Jacoba A van de Kreeke, Stanley Darma, Jill M P L Chan Pin Yin, H Stevie Tan, Michael D Abramoff, Jos W R Twisk, Frank D Verbraa. The spatial relation of diabetic retinal neurodegeneration with diabetic retinopathy. PloS one. vol 15. issue 4. 2020-07-27. PMID:32298369. |
in this longitudinal study, we aimed to clarify whether the rate of drn is associated with the development/presence of dr within 4 different quadrants of the retina. |
2020-07-27 |
2023-08-13 |
Not clear |
| Hisashi Yokomizo, Yasutaka Maeda, Kyoungmin Park, Allen C Clermont, Sonia L Hernandez, Ward Fickweiler, Qian Li, Chih-Hao Wang, Samantha M Paniagua, Fabricio Simao, Atsushi Ishikado, Bei Sun, I-Hsien Wu, Sayaka Katagiri, David M Pober, Liane J Tinsley, Robert L Avery, Edward P Feener, Timothy S Kern, Hillary A Keenan, Lloyd Paul Aiello, Jennifer K Sun, George L Kin. Retinol binding protein 3 is increased in the retina of patients with diabetes resistant to diabetic retinopathy. Science translational medicine. vol 11. issue 499. 2020-07-24. PMID:31270273. |
proteomic analysis of retina and vitreous identified retinol binding protein 3 (rbp3), a retinol transport protein secreted mainly by the photoreceptors, as elevated in medalist patients protected from advanced dr. mass spectrometry and protein expression analysis identified an inverse association between vitreous rbp3 concentration and dr severity. |
2020-07-24 |
2023-08-13 |
Not clear |
| Xianliang Qiu, Xian Wang, Peipei Hong, Min Liu, Qing Wen, Qiu Che. Retinal blood oxygen saturation and vascular endothelial growth factor-A in early diabetic retinopathy: A protocol for systematic review and meta-analysis. Medicine. vol 99. issue 24. 2020-06-29. PMID:32541481. |
therefore, we decided to conduct a systematic review and meta-analysis to find out the connection of them and provide robust evidence on the mechanism underlying this connection to help us better understand the pathophysiology behind the hypoxic retina and find better ways to treat dr. |
2020-06-29 |
2023-08-13 |
Not clear |
| Constanze Stumpf, Tobias Wimmer, Birgit Lorenz, Knut Stiege. Creation of different bioluminescence resonance energy transfer based biosensors with high affinity to VEGF. PloS one. vol 15. issue 3. 2020-06-26. PMID:32214330. |
in age-related macular degeneration (amd) or diabetic retinopathy (dr), hypoxia and inflammatory processes lead to an upregulation of the vascular endothelial growth factor (vegf) expression and thereby to pathological neovascularisation with incorrectly formed vessels prone to damage, thus increasing the vascular permeability and the risk of bleeding and oedema in the retina. |
2020-06-26 |
2023-08-13 |
Not clear |
| Tian Niu, Mengya Zhao, Yan Jiang, Xindan Xing, Xin Shi, Lu Cheng, Huiyi Jin, Kun Li. Endomucin restores depleted endothelial glycocalyx in the retinas of streptozotocin-induced diabetic rats. FASEB journal : official publication of the Federation of American Societies for Experimental Biology. vol 33. issue 12. 2020-06-09. PMID:31545913. |
we then overexpressed emcn in the retina with adeno-associated virus and induced dr with streptozotocin (stz). |
2020-06-09 |
2023-08-13 |
human |
| Odunayo O Mugisho, Colin R Green, Jie Zhang, Monica L Acosta, Ilva D Rupentha. Connexin43 hemichannels: A potential drug target for the treatment of diabetic retinopathy. Drug discovery today. vol 24. issue 8. 2020-05-11. PMID:30690195. |
diabetic retinopathy (dr) is a chronic vascular disease of the retina that causes vision loss in patients with type 1 and type 2 diabetes, and is associated with vascular dysfunction and occlusion, retinal oedema, haemorrhage and inadequate growth of new blood vessels. |
2020-05-11 |
2023-08-13 |
Not clear |
| Javier Zarranz-Ventura, Marina Barraso, Anibal Alé-Chilet, Teresa Hernandez, Cristian Oliva, Jesus Gascón, Anna Sala-Puigdollers, Marc Figueras-Roca, Irene Vinagre, Emilio Ortega, Enric Esmatjes, Alfredo Ada. Evaluation of microvascular changes in the perifoveal vascular network using optical coherence tomography angiography (OCTA) in type I diabetes mellitus: a large scale prospective trial. BMC medical imaging. vol 19. issue 1. 2020-05-08. PMID:31752726. |
diabetic retinopathy (dr) is the leading cause of blindness in type 1 diabetes mellitus (dm) patients, as a consequence of impaired blood flow in the retina. |
2020-05-08 |
2023-08-13 |
Not clear |
| Satish Patnaik, Subhadra Jalali, Manjunath B Joshi, Kapaettu Satyamoorthy, Inderjeet Kau. Metabolomics Applicable to Retinal Vascular Diseases. Methods in molecular biology (Clifton, N.J.). vol 1996. 2020-04-06. PMID:31127565. |
human retina is metabolically highly active, and retinal vascular diseases such as age-related macular degeneration (amd), diabetic retinopathy (dr), retinal vein occlusion (rvo), central retinal artery occlusion, and retinopathy of prematurity (rop) are often associated with the disruptions in metabolic activities. |
2020-04-06 |
2023-08-13 |
human |
| Pablo Amil, Cesar F Reyes-Manzano, Lev Guzmán-Vargas, Irene Sendiña-Nadal, Cristina Masolle. Network-based features for retinal fundus vessel structure analysis. PloS one. vol 14. issue 7. 2020-03-16. PMID:31344132. |
retinal fundus imaging is a non-invasive method that allows visualizing the structure of the blood vessels in the retina whose features may indicate the presence of diseases such as diabetic retinopathy (dr) and glaucoma. |
2020-03-16 |
2023-08-13 |
Not clear |