| Publication |
Sentence |
Publish Date |
Extraction Date |
Species |
| Rehana Khan, Mahesh Shanmugam, Rajesh Ramanjulu, Jay Chablani, Niharika Singh, Avadhesh Oli, Rajiv Rama. Influence of segmental supply of Cilioretinal artery on morphology of diabetic macular edema. BMC ophthalmology. vol 21. issue 1. 2021-05-14. PMID:33478406. |
the supply of cilioretinal artery (cra) to different layers of the retina influences retinal pathologies such as diabetic retinopathy (dr). |
2021-05-14 |
2023-08-13 |
Not clear |
| Gaganashree Shivashankar, Julie C Lim, Monica L Acost. Proinflammatory cytokines trigger biochemical and neurochemical changes in mouse retinal explants exposed to hyperglycemic conditions. Molecular vision. vol 26. 2021-05-10. PMID:32300272. |
diabetic retinopathy (dr) is one of the most frequent complications of diabetes affecting the retina and eventually causing vision impairment. |
2021-05-10 |
2023-08-13 |
mouse |
| S Sreenivasa Reddy, Y K Prabhakar, Ch Uday Kumar, P Yadagiri Reddy, G Bhanuprakash Redd. Effect of vitamin B Molecular vision. vol 26. 2021-05-10. PMID:32355441. |
effect of vitamin b diabetic retinopathy (dr) is the most common complication of diabetes involving microvasculature and neuronal alterations in the retina. |
2021-05-10 |
2023-08-13 |
Not clear |
| Snježana Kaštelan, Ivana Orešković, Filip Bišćan, Helena Kaštelan, Antonela Gverović Antunic. Inflammatory and angiogenic biomarkers in diabetic retinopathy. Biochemia medica. vol 30. issue 3. 2021-05-06. PMID:32774120. |
biomarkers related to dr can be measured in the blood, retina, vitreous, aqueous humour and recently in tears. |
2021-05-06 |
2023-08-13 |
Not clear |
| Snježana Kaštelan, Ivana Orešković, Filip Bišćan, Helena Kaštelan, Antonela Gverović Antunic. Inflammatory and angiogenic biomarkers in diabetic retinopathy. Biochemia medica. vol 30. issue 3. 2021-05-06. PMID:32774120. |
as the retina represents a small part of total body mass, a circulating biomarker for dr needs to be highly specific. |
2021-05-06 |
2023-08-13 |
Not clear |
| Fei Cai, Huanzong Jiang, Yan Li, Qin Li, Chao Yan. Upregulation of long non-coding RNA SNHG16 promotes diabetes-related RMEC dysfunction via activating NF-κB and PI3K/AKT pathways. Molecular therapy. Nucleic acids. vol 24. 2021-04-28. PMID:33898104. |
diabetic retinopathy (dr) is a severe diabetes-induced eye disease, in which its pathological phenomena basically include abnormal proliferation, migration, and angiogenesis of microvascular endothelial cells in the retina. |
2021-04-28 |
2023-08-13 |
human |
| Ana L Matos, Diogo F Bruno, António F Ambrósio, Paulo F Santo. The Benefits of Flavonoids in Diabetic Retinopathy. Nutrients. vol 12. issue 10. 2021-04-19. PMID:33081260. |
since it is known that diabetes induces oxidative stress and inflammation in the retina leading to neuronal death in the early stages of the disease, the use of these compounds can prove to be beneficial in the prevention or treatment of dr. |
2021-04-19 |
2023-08-13 |
Not clear |
| Liping Xue, Cheng Xiong, Juanjuan Li, Yuling Ren, Liwei Zhang, Kangwei Jiao, Chen Chen, Peng Din. miR-200-3p suppresses cell proliferation and reduces apoptosis in diabetic retinopathy via blocking the TGF-β2/Smad pathway. Bioscience reports. vol 40. issue 11. 2021-04-12. PMID:33150936. |
in the present study, we observed that mir-200a-3p was significantly decreased, while transforming growth factor-β2 (tgf-β2) expression was up-regulated in arpe-19 cells treated with hg and retina tissues of dr rats. |
2021-04-12 |
2023-08-13 |
rat |
| Kan Shao, Liuqing Xi, Zhen Cang, Cheng Chen, Shan Huan. Knockdown of NEAT1 exerts suppressive effects on diabetic retinopathy progression via inactivating TGF-β1 and VEGF signaling pathways. Journal of cellular physiology. vol 235. issue 12. 2021-04-06. PMID:32356340. |
here, we found the neat1 level was significantly elevated in patients with dr, in the retina of diabetic rats and mice. |
2021-04-06 |
2023-08-13 |
mouse |
| Xiaofeng Ye, Hui Ren, Tingting Jiang, Ting Zhang, Gang L. Effect of diabetes blood-stasis syndrome and Xuefu Zhuyu decoction on ROS-ERK1/2 signaling pathway in rat retina Müller cells. Cytotechnology. vol 72. issue 2. 2021-04-02. PMID:32112164. |
this research aimed to investigate whether diabetic blood-stasis syndrome had a relationship with ros-erk1/2 signaling pathway in rat retina müller cells and explore the effects of traditional chinese drugs designed for promoting blood circulation to remove blood stasis on diabetic retinopathy (dr) treatment. |
2021-04-02 |
2023-08-13 |
rat |
| Francesco Bandello, Maria Vittoria Cicinell. 19th EURETINA Congress Keynote Lecture: Diabetic Retinopathy Today. Ophthalmologica. Journal international d'ophtalmologie. International journal of ophthalmology. Zeitschrift fur Augenheilkunde. vol 243. issue 3. 2021-03-26. PMID:32015239. |
nowadays, thanks to more advanced imaging techniques, namely optical coherence tomography (oct), oct angiography, and wide-field imaging (imaging up to 200° of the retina in a single shot), it became clear that other elements participate in the occurrence of dr and dme, including inflammation and neurodegeneration. |
2021-03-26 |
2023-08-13 |
Not clear |
| Yue He, Yujiao Dan, Xiaorong Gao, Li Huang, Hongbin Lv, Jie Che. DNMT1-mediated lncRNA MEG3 methylation accelerates endothelial-mesenchymal transition in diabetic retinopathy through the PI3K/Akt/mTOR signaling pathway. American journal of physiology. Endocrinology and metabolism. vol 320. issue 3. 2021-03-26. PMID:33284093. |
this study aimed to determine the underlying mechanism of lncrna maternally expressed gene 3 (meg3) in association with dna methyltransferase 1 (dnmt1) in the endothelial-mesenchymal transition (endmt) that occurs in dr. a rat model of dr was induced by streptozotocin (stz) injection, and a high-glucose (hg)-induced cell model was established by exposing microvascular endothelial cells obtained from retina of rats to hg. |
2021-03-26 |
2023-08-13 |
rat |
| Kostadin Dimov Rolev, Xing-Sheng Shu, Ying Yin. Targeted pharmacotherapy against neurodegeneration and neuroinflammation in early diabetic retinopathy. Neuropharmacology. vol 187. 2021-03-23. PMID:33582150. |
these findings have opened up opportunities for therapies, such as inhibition of gsk-3β, glial cell activation, glutamate excitotoxicity and the use of neuroprotective drugs targeting early neurodegenerative processes in the retina and halting the progression of dr before the manifestation of microvascular abnormalities. |
2021-03-23 |
2023-08-13 |
Not clear |
| Shuai Wang, Shanshan Du, Wenzhan Wang, Fengyan Zhan. Therapeutic investigation of quercetin nanomedicine in a zebrafish model of diabetic retinopathy. Biomedicine & pharmacotherapy = Biomedecine & pharmacotherapie. vol 130. 2021-02-25. PMID:32745912. |
diabetic retinopathy (dr) is progressive damage to the retina and it's caused by damage to the blood-retinal barrier. |
2021-02-25 |
2023-08-13 |
zebrafish |
| Ka-Ho Wong, Katherine Hu, Cecilia Peterson, Nazanin Sheibani, Georgios Tsivgoulis, Jennifer J Majersik, Adam H de Haveno. Diabetic Retinopathy and Risk of Stroke: A Secondary Analysis of the ACCORD Eye Study. Stroke. vol 51. issue 12. 2021-02-17. PMID:33019896. |
diabetic retinopathy (dr) is a common microvascular complication of diabetes, which causes damage to the retina and may lead to rapid vision loss. |
2021-02-17 |
2023-08-13 |
Not clear |
| Noura M Almutairi, Shoroog Alahmadi, Mona Alharbi, Sarah Gotah, Majed Alharb. The Association Between HbA1c and Other Biomarkers With the Prevalence and Severity of Diabetic Retinopathy. Cureus. vol 13. issue 1. 2021-02-11. PMID:33564524. |
diabetes mellitus (dm) is considered to be a significant public health problem globally. according to the american society of retina specialists, diabetic retinopathy (dr) is a complication of diabetes that causes damage to the blood vessels of the retina. in a japanese study showed that hba1c and fasting blood glucose values can be considered as predictors for the future development of dr. |
2021-02-11 |
2023-08-13 |
Not clear |
| Malgorzata Mrugacz, Anna Bryl, Katarzyna Zoren. Retinal Vascular Endothelial Cell Dysfunction and Neuroretinal Degeneration in Diabetic Patients. Journal of clinical medicine. vol 10. issue 3. 2021-02-10. PMID:33504108. |
lesions observed in the retina in the course of diabetes, referred to as diabetic retinopathy (dr), are caused by vascular abnormalities and are ischemic in nature. |
2021-02-10 |
2023-08-13 |
Not clear |
| Wenjun Li, Hongxia Xia. Dihydromyricetin Alleviates High Glucose-Induced Oxidative Stress and Apoptosis in Human Retinal Pigment Epithelial Cells by Downregulating miR-34a Expression. Diabetes, metabolic syndrome and obesity : targets and therapy. vol 14. 2021-02-06. PMID:33536772. |
diabetic retinopathy (dr) is one of the most common microvascular complications of diabetes mellitus, which leads to neuronal and vascular dysfunction in the retina with a final outcome of complete loss of vision. |
2021-02-06 |
2023-08-13 |
human |
| Basak Can Ermerak, Ozgur Yalcinbayir, Erdal Eren, Elif Sobu, Cansu Erseven, Ahmet Ali Yuce. Evaluation of choroidal thickness in children with type 1 diabetes: the role of optical coherence tomography in diabetic retinopathy screening. Clinical pediatric endocrinology : case reports and clinical investigations : official journal of the Japanese Society for Pediatric Endocrinology. vol 30. issue 1. 2021-01-16. PMID:33446951. |
the present study aimed to evaluate choroidal changes and alternations within the structure of the retina prior to visible morphologic signs of diabetic retinopathy (dr) in pediatric type 1 diabetes (t1d) cases. |
2021-01-16 |
2023-08-13 |
Not clear |
| Ping Duan, Siyu Chen, Yuxiao Zeng, Haiwei Xu, Yong Li. Osteopontin Upregulates Col IV Expression by Repressing miR-29a in Human Retinal Capillary Endothelial Cells. Molecular therapy. Nucleic acids. vol 20. 2021-01-10. PMID:32182570. |
in this study, 51 differentially expressed micrornas (mirnas; 42 mirnas upregulated and 9 mirnas downregulated) were first identified in retina of streptozotocin (stz)-induced diabetic mice with dr. |
2021-01-10 |
2023-08-13 |
mouse |