| Publication |
Sentence |
Publish Date |
Extraction Date |
Species |
| Vishvesh H Shende, Simon McArthur, Glenda E Gillies, Jolanta Opacka-Juffr. Astroglial Plasticity Is Implicated in Hippocampal Remodelling in Adult Rats Exposed to Antenatal Dexamethasone. Neural plasticity. vol 2015. 2016-04-19. PMID:26345609. |
morphological analysis indicated that numbers of astroglial primary processes were not affected in any of the hippocampal subregions analysed but significant reductions in the total primary process length were observed in ca1 by 32%, ca3 by 50%, and dg by 25%. |
2016-04-19 |
2023-08-13 |
rat |
| Carla Nasca, Danielle Zelli, Benedetta Bigio, Sonia Piccinin, Sergio Scaccianoce, Robert Nisticò, Bruce S McEwe. Stress dynamically regulates behavior and glutamatergic gene expression in hippocampus by opening a window of epigenetic plasticity. Proceedings of the National Academy of Sciences of the United States of America. vol 112. issue 48. 2016-04-15. PMID:26627246. |
they reveal a key role for epigenetic up- and down-regulation of the putative presynaptic type 2 metabotropic glutamate (mglu2) receptors and the postsynaptic nr1/nmda receptors in the hippocampus and particularly in the dentate gyrus (dg), a region of active neurogenesis and a target of antidepressant treatment. |
2016-04-15 |
2023-08-13 |
mouse |
| Peter Falkai, Johann Steiner, Berend Malchow, Jawid Shariati, Andreas Knaus, Hans-Gert Bernstein, Thomas Schneider-Axmann, Theo Kraus, Alkomiet Hasan, Bernhard Bogerts, Andrea Schmit. Oligodendrocyte and Interneuron Density in Hippocampal Subfields in Schizophrenia and Association of Oligodendrocyte Number with Cognitive Deficits. Frontiers in cellular neuroscience. vol 10. 2016-04-12. PMID:27065804. |
in schizophrenia, previous stereological post-mortem investigations of anterior, posterior, and total hippocampal subfields showed no alterations in total neuron number but did show decreased oligodendrocyte numbers in ca4, an area that corresponds to the polymorph layer of the dentate gyrus (dg). |
2016-04-12 |
2023-08-13 |
Not clear |
| Peter Falkai, Johann Steiner, Berend Malchow, Jawid Shariati, Andreas Knaus, Hans-Gert Bernstein, Thomas Schneider-Axmann, Theo Kraus, Alkomiet Hasan, Bernhard Bogerts, Andrea Schmit. Oligodendrocyte and Interneuron Density in Hippocampal Subfields in Schizophrenia and Association of Oligodendrocyte Number with Cognitive Deficits. Frontiers in cellular neuroscience. vol 10. 2016-04-12. PMID:27065804. |
in the present study, we found no significant influence of definite cognitive deficits in the posterior part of the hippocampus, whereas in the entire hippocampus sz with definite cognitive deficits showed decreased oligodendrocyte numbers in the left (p = 0.050) and right (p = 0.050) dg and left ca2/3 (p = 0.050). |
2016-04-12 |
2023-08-13 |
Not clear |
| Qingtao Gao, Se Jin Jeon, Hyun Ah Jung, Hyung Eun Lee, Se Jin Park, Younghwan Lee, Younghwa Lee, Sang Yoon Ko, Boseong Kim, Jae Sue Choi, Jong Hoon Ry. Nodakenin Enhances Cognitive Function and Adult Hippocampal Neurogenesis in Mice. Neurochemical research. vol 40. issue 7. 2016-04-11. PMID:25998887. |
in addition, sub-chronic administration of nodakenin increased the number of 5-bromo-2-deoxyuridine (brdu)-positive cells in the hippocampal dentate gyrus (dg) region. |
2016-04-11 |
2023-08-13 |
mouse |
| Qingtao Gao, Se Jin Jeon, Hyun Ah Jung, Hyung Eun Lee, Se Jin Park, Younghwan Lee, Younghwa Lee, Sang Yoon Ko, Boseong Kim, Jae Sue Choi, Jong Hoon Ry. Nodakenin Enhances Cognitive Function and Adult Hippocampal Neurogenesis in Mice. Neurochemical research. vol 40. issue 7. 2016-04-11. PMID:25998887. |
these findings suggest that the sub-chronic administration of nodakenin enhances adult hippocampal neurogenesis in the dg region via akt-gsk-3β signaling and this increase may be associated with nodakenin's positive effect on cognitive processing. |
2016-04-11 |
2023-08-13 |
mouse |
| Vassilis Cutsuridis, Panayiota Poiraz. A computational study on how theta modulated inhibition can account for the long temporal windows in the entorhinal-hippocampal loop. Neurobiology of learning and memory. vol 120. 2016-04-08. PMID:25721691. |
the model shows that the experimentally reported long temporal delays in the dg, ca3 and ca1 hippocampal regions are due to theta modulated somatic and axonic inhibition. |
2016-04-08 |
2023-08-13 |
Not clear |
| Ryan T Jones, Albert M Barth, Laurel D Ormiston, Istvan Mod. Evolution of temporal and spectral dynamics of pathologic high-frequency oscillations (pHFOs) during epileptogenesis. Epilepsia. vol 56. issue 12. 2016-04-08. PMID:26514993. |
in temporal lobe epilepsy (tle), pathologic high frequency oscillations (phfos, 200-600 hz) are present in the hippocampus, especially the dentate gyrus (dg). |
2016-04-08 |
2023-08-13 |
mouse |
| Xia Jiang, Gao-Shang Chai, Zhi-Hao Wang, Yu Hu, Xiao-Guang Li, Zhi-Wei Ma, Qun Wang, Jian-Zhi Wang, Gong-Ping Li. Spatial training preserves associative memory capacity with augmentation of dendrite ramification and spine generation in Tg2576 mice. Scientific reports. vol 5. 2016-04-05. PMID:25820815. |
we also found that spatial training enhanced long term potentiation, dendrite ramification and spine generation in hippocampal dentate gyrus (dg) and ca1 neurons at 24 h after the training. |
2016-04-05 |
2023-08-13 |
mouse |
| Takeshi Takarada, Noritaka Nakamichi, Takami Kakuda, Ryota Nakazato, Hiroshi Kokubo, Shinsuke Ikeno, Saki Nakamura, Eiichi Hinoi, Yukio Yoned. Daily oral intake of theanine prevents the decline of 5-bromo-2'-deoxyuridine incorporation in hippocampal dentate gyrus with concomitant alleviation of behavioral abnormalities in adult mice with severe traumatic stress. Journal of pharmacological sciences. vol 127. issue 3. 2016-04-05. PMID:25837925. |
we demonstrated a positive correlation between the transient decline of 5-bromo-2'-deoxyuridine (brdu) incorporation in the hippocampal dentate gyrus (dg) and long-lasting behavioral abnormalities in mice with traumatic stress. |
2016-04-05 |
2023-08-13 |
mouse |
| Takeshi Takarada, Noritaka Nakamichi, Takami Kakuda, Ryota Nakazato, Hiroshi Kokubo, Shinsuke Ikeno, Saki Nakamura, Eiichi Hinoi, Yukio Yoned. Daily oral intake of theanine prevents the decline of 5-bromo-2'-deoxyuridine incorporation in hippocampal dentate gyrus with concomitant alleviation of behavioral abnormalities in adult mice with severe traumatic stress. Journal of pharmacological sciences. vol 127. issue 3. 2016-04-05. PMID:25837925. |
these results suggest that theanine alleviates behavioral abnormalities together with prevention of the transient decline of brdu incorporation in the hippocampal dg in adult mice with severe traumatic stress. |
2016-04-05 |
2023-08-13 |
mouse |
| Z Zhang, H Wang, Z Jin, X Cai, N Gao, X Cui, P Liu, J Zhang, S Yang, X Yan. Downregulation of survivin regulates adult hippocampal neurogenesis and apoptosis, and inhibits spatial learning and memory following traumatic brain injury. Neuroscience. vol 300. 2016-03-29. PMID:25987205. |
our data showed that survivin knockdown inhibits the proliferation and differentiation of neural precursor cells (npcs) in the dg of the hippocampus soon after tbi. |
2016-03-29 |
2023-08-13 |
mouse |
| Rachele Salvi, Tobias Steigleder, Johannes C M Schlachetzki, Elisabeth Waldmann, Stefan Schwab, Beate Winner, Jürgen Winkler, Zacharias Koh. Distinct Effects of Chronic Dopaminergic Stimulation on Hippocampal Neurogenesis and Striatal Doublecortin Expression in Adult Mice. Frontiers in neuroscience. vol 10. 2016-03-25. PMID:27013940. |
while adult neurogenesis is considered to be restricted to the hippocampal dentate gyrus (dg) and the subventricular zone (svz), recent studies in humans and rodents provide evidence for newly generated neurons in regions generally considered as non-neurogenic, e.g., the striatum. |
2016-03-25 |
2023-08-13 |
mouse |
| Jianxing Xiang, Sen Yan, Shi-Hua Li, Xiao-Jiang L. Postnatal loss of hap1 reduces hippocampal neurogenesis and causes adult depressive-like behavior in mice. PLoS genetics. vol 11. issue 4. 2016-03-24. PMID:25875952. |
furthermore, early hap1 depletion impaired postnatal neurogenesis in the dentate gyrus (dg) of the hippocampus and reduced the level of c-kit, a protein expressed in neuroproliferative zones of the rodent brain and that is stabilized by hap1. |
2016-03-24 |
2023-08-13 |
mouse |
| D H Bergin, Y Jing, H Zhang, P Li. A single intracerebroventricular Aβ25-35 infusion leads to prolonged alterations in arginine metabolism in the rat hippocampus and prefrontal cortex. Neuroscience. vol 298. 2016-03-21. PMID:25907447. |
infusion of pre-aggregated aβ25-35 (the neurotoxic domain of the full-length aβ) altered arginine metabolism in the rat hippocampus (particularly the ca2/3 and dentate gyrus (dg) sub-regions) and prefrontal cortex (pfc) at the time point of 8 days post-infusion. |
2016-03-21 |
2023-08-13 |
rat |
| Yayoi Ikeda, Masa-Aki Iked. Cyclin E marks quiescent neural stem cells and caspase-3-positive newborn cells during adult hippocampal neurogenesis in mice. Neuroscience letters. vol 607. 2016-03-21. PMID:26391744. |
in the present study, we examined expression of cyclin e in the mouse hippocampal dentate gyrus (dg), a region of neurogenesis in adulthood, using immunofluorescence. |
2016-03-21 |
2023-08-13 |
mouse |
| Somayeh Zargooshnia, Siamak Shahidi, Fatemeh Ghahremanitamadon, Ali Nikkhah, Mehdi Mehdizadeh, Sara Soleimani As. The protective effect of Borago Officinalis extract on amyloid β (25-35)-induced long term potentiation disruption in the dentate gyrus of male rats. Metabolic brain disease. vol 30. issue 1. 2016-03-17. PMID:25060965. |
in the present study we have examined the protective effects of borago officinalis (borage) extract on amyloid β (aβ)--induced long term potentiation (ltp) disruption in hippocampal dentate gyrus (dg). |
2016-03-17 |
2023-08-13 |
rat |
| Somayeh Zargooshnia, Siamak Shahidi, Fatemeh Ghahremanitamadon, Ali Nikkhah, Mehdi Mehdizadeh, Sara Soleimani As. The protective effect of Borago Officinalis extract on amyloid β (25-35)-induced long term potentiation disruption in the dentate gyrus of male rats. Metabolic brain disease. vol 30. issue 1. 2016-03-17. PMID:25060965. |
this data suggest that aβ (25-35) can effectively inhibit ltp in the granular cells of the dg in hippocampus, and borage supplementation reverse the synaptic plasticity in dg following aβ treatment and that borage consumption may lead to an improvement of ad-induced cognitive dysfunction. |
2016-03-17 |
2023-08-13 |
rat |
| Weijun Xuan, Tanupriya Agrawal, Liyi Huang, Gaurav K Gupta, Michael R Hambli. Low-level laser therapy for traumatic brain injury in mice increases brain derived neurotrophic factor (BDNF) and synaptogenesis. Journal of biophotonics. vol 8. issue 6. 2016-03-03. PMID:25196192. |
brain-derived neurotrophic factor (bdnf) was significantly upregulated by laser treatment in the dentate gyrus of the hippocampus (dg) and the subventricular zone (svz) but not in the perilesional cortex (lesion) at day 7 but not at day 28. |
2016-03-03 |
2023-08-13 |
mouse |
| Anna Engstrom, Hao Wang, Zhengui Xi. Lead decreases cell survival, proliferation, and neuronal differentiation of primary cultured adult neural precursor cells through activation of the JNK and p38 MAP kinases. Toxicology in vitro : an international journal published in association with BIBRA. vol 29. issue 5. 2016-02-29. PMID:25967738. |
adult hippocampal neurogenesis is the process whereby adult neural precursor cells (anpcs) in the subgranular zone (sgz) of the dentate gyrus (dg) generate adult-born, functional neurons in the hippocampus. |
2016-02-29 |
2023-08-13 |
mouse |