| Publication |
Sentence |
Publish Date |
Extraction Date |
Species |
| Guillaume Martel, Shusaku Uchida, Charles Hevi, Itzamarie Chévere-Torres, Ileana Fuentes, Young Jin Park, Hannah Hafeez, Hirotaka Yamagata, Yoshifumi Watanabe, Gleb P Shumyatsk. Genetic Demonstration of a Role for Stathmin in Adult Hippocampal Neurogenesis, Spinogenesis, and NMDA Receptor-Dependent Memory. The Journal of neuroscience : the official journal of the Society for Neuroscience. vol 36. issue 4. 2016-06-01. PMID:26818507. |
neurogenesis and memory formation are essential features of the dentate gyrus (dg) area of the hippocampus, but to what extent the mechanisms responsible for both processes overlap remains poorly understood. |
2016-06-01 |
2023-08-13 |
mouse |
| Carmen Viva. Adult Hippocampal Neurogenesis, Aging and Neurodegenerative Diseases: Possible Strategies to Prevent Cognitive Impairment. Current topics in medicinal chemistry. vol 15. issue 21. 2016-05-31. PMID:26059358. |
however, this neurogenic capacity is limited to two brain areas, the dentate gyrus (dg of the hippocampus and the subventricular zone (svz of the lateral ventricle. |
2016-05-31 |
2023-08-13 |
Not clear |
| Angélica Pupin Schiavon, Jéssica Mendes Bonato, Humberto Milani, Francisco Silveira Guimarães, Rúbia Maria Weffort de Oliveir. Influence of single and repeated cannabidiol administration on emotional behavior and markers of cell proliferation and neurogenesis in non-stressed mice. Progress in neuro-psychopharmacology & biological psychiatry. vol 64. 2016-05-31. PMID:26187374. |
despite its antidepressant-like effects in the tst, repeated cbd administration at a higher dose (30 mg/kg) decreased cell proliferation and neurogenesis in the hippocampal dg and svz. |
2016-05-31 |
2023-08-13 |
mouse |
| Davide Guerrieri, Henriette van Praa. Exercise-mimetic AICAR transiently benefits brain function. Oncotarget. vol 6. issue 21. 2016-05-20. PMID:26286955. |
at the time-points where we observed equivalent running- and aicar-induced muscle pampk levels (7 and 14 days), cell proliferation, synaptic plasticity and gene expression, as well as markers of oxidative stress and inflammation in the dentate gyrus (dg) of the hippocampus and lateral entorhinal cortex (lec) were evaluated. |
2016-05-20 |
2023-08-13 |
mouse |
| Caine C Smith, Diane Guévremont, Joanna M Williams, Ruth M A Nappe. Apoptotic cell death and temporal expression of apoptotic proteins Bcl-2 and Bax in the hippocampus, following binge ethanol in the neonatal rat model. Alcoholism, clinical and experimental research. vol 39. issue 1. 2016-05-19. PMID:25623404. |
this study investigates acute apoptotic cell death in hippocampal regions ca1, ca3, and dentate gyrus (dg) following a binge etoh exposure on postnatal day (pn) 6, pn8, or pn6 + 8 and the alteration in pro- and anti-apoptotic proteins following a single etoh binge on pn6. |
2016-05-19 |
2023-08-13 |
rat |
| Dayu Sun, Junhua Chen, Xiaohang Bao, Yulong Cai, Jinghui Zhao, Jing Huang, Wei Huang, Xiaotang Fan, Haiwei X. Protection of Radial Glial-Like Cells in the Hippocampus of APP/PS1 Mice: a Novel Mechanism of Memantine in the Treatment of Alzheimer's Disease. Molecular neurobiology. vol 52. issue 1. 2016-05-17. PMID:25195698. |
the failure of adult neurogenesis in the hippocampal dentate gyrus (dg) is closely correlated with memory decline in alzheimer's disease (ad). |
2016-05-17 |
2023-08-13 |
mouse |
| Dayu Sun, Junhua Chen, Xiaohang Bao, Yulong Cai, Jinghui Zhao, Jing Huang, Wei Huang, Xiaotang Fan, Haiwei X. Protection of Radial Glial-Like Cells in the Hippocampus of APP/PS1 Mice: a Novel Mechanism of Memantine in the Treatment of Alzheimer's Disease. Molecular neurobiology. vol 52. issue 1. 2016-05-17. PMID:25195698. |
radial glial-like cells (rgls) localized to the adult dg generate intermediate progenitor cells and immature neurons and thus contribute to adult hippocampus neurogenesis. |
2016-05-17 |
2023-08-13 |
mouse |
| Dayu Sun, Junhua Chen, Xiaohang Bao, Yulong Cai, Jinghui Zhao, Jing Huang, Wei Huang, Xiaotang Fan, Haiwei X. Protection of Radial Glial-Like Cells in the Hippocampus of APP/PS1 Mice: a Novel Mechanism of Memantine in the Treatment of Alzheimer's Disease. Molecular neurobiology. vol 52. issue 1. 2016-05-17. PMID:25195698. |
mem could enhance hippocampal neurogenesis and increase the number of rgls in the dg subgranular zone (dg-sgz) of app/ps1 mice of both ages. |
2016-05-17 |
2023-08-13 |
mouse |
| C Yang, Y Shirayama, J-c Zhang, Q Ren, W Yao, M Ma, C Dong, K Hashimot. R-ketamine: a rapid-onset and sustained antidepressant without psychotomimetic side effects. Translational psychiatry. vol 5. 2016-05-11. PMID:26327690. |
furthermore, r-ketamine induced a more potent beneficial effect on decreased dendritic spine density, bdnf-trkb signaling and synaptogenesis in the prefrontal cortex (pfc), ca3 and dentate gyrus (dg) of the hippocampus from depressed mice compared with s-ketamine. |
2016-05-11 |
2023-08-13 |
mouse |
| Conghui Wang, Tingting Chen, Guoxi Li, Libin Zhou, Sha Sha, Ling Che. Simvastatin prevents β-amyloid(25-35)-impaired neurogenesis in hippocampal dentate gyrus through α7nAChR-dependent cascading PI3K-Akt and increasing BDNF via reduction of farnesyl pyrophosphate. Neuropharmacology. vol 97. 2016-05-10. PMID:26051402. |
in hippocampal dentate gyrus (dg), β-amyloid (aβ) selectively impairs survival and neurite growth of newborn neurons in the 2(nd) week after birth. |
2016-05-10 |
2023-08-13 |
mouse |
| Moira Marizzoni, Luigi Antelmi, Beatriz Bosch, David Bartrés-Faz, Bernhard W Müller, Jens Wiltfang, Ute Fiedler, Luca Roccatagliata, Agnese Picco, Flavio Nobili, Olivier Blin, Stephanie Bombois, Renaud Lopes, Julien Sein, Jean-Philippe Ranjeva, Mira Didic, Hélène Gros-Dagnac, Pierre Payoux, Giada Zoccatelli, Franco Alessandrini, Alberto Beltramello, Núria Bargalló, Antonio Ferretti, Massimo Caulo, Marco Aiello, Carlo Cavaliere, Andrea Soricelli, Nicola Salvadori, Lucilla Parnetti, Roberto Tarducci, Piero Floridi, Magda Tsolaki, Manos Constantinidis, Antonios Drevelegas, Paolo Maria Rossini, Camillo Marra, Karl-Titus Hoffmann, Tilman Hensch, Peter Schönknecht, Joost P Kuijer, Pieter Jelle Visser, Frederik Barkhof, Régis Bordet, Giovanni B Frisoni, Jorge Jovicic. Longitudinal reproducibility of automatically segmented hippocampal subfields: A multisite European 3T study on healthy elderly. Human brain mapping. vol 36. issue 9. 2016-05-09. PMID:26043939. |
volumetric and spatial reproducibility across mri sites were very good for the whole hippocampus, ca2-3, ca4-dentate gyrus (dg), subiculum (reproducibility error∼2% and dice > 0.90), good for ca1 and presubiculum (reproducibility error ∼ 5% and dice ∼ 0.90), and poorer for fimbria and hippocampal fissure (reproducibility error ∼ 15% and dice < 0.80). |
2016-05-09 |
2023-08-13 |
human |
| Sha Sha, Juan Hong, Wei-Jun Qu, Zi-Hong Lu, Lin Li, Wen-Feng Yu, Ling Che. Sex-related neurogenesis decrease in hippocampal dentate gyrus with depressive-like behaviors in sigma-1 receptor knockout mice. European neuropsychopharmacology : the journal of the European College of Neuropsychopharmacology. vol 25. issue 8. 2016-05-06. PMID:25983018. |
male sigma-1 receptor knockout (σ1r(-/-)) mice showed depressive-like phenotype with deficit in the survival of newly generated neuronal cells in the hippocampal dentate gyrus (dg), but female σ1r(-/-) mice did not. |
2016-05-06 |
2023-08-13 |
mouse |
| Ioannis K Papazoglou, Arnaud Jean, Arieh Gertler, Mohammed Taouis, Claire-Marie Vache. Hippocampal GSK3β as a Molecular Link Between Obesity and Depression. Molecular neurobiology. vol 52. issue 1. 2016-05-02. PMID:25169083. |
to address this issue, we investigated the impact of high-fat (hf)-diet-induced obesity on depressive-like behavior and on serotonin (5-ht)-dependent akt/glycogen synthase kinase 3β (gsk3β) signaling in the dentate gyrus (dg) of the hippocampus, which has been associated with mood regulation. |
2016-05-02 |
2023-08-13 |
rat |
| Donnahue Dennie, Jean-Pierre Louboutin, David S Straye. Migration of bone marrow progenitor cells in the adult brain of rats and rabbits. World journal of stem cells. vol 8. issue 4. 2016-04-26. PMID:27114746. |
transgene-positive cells were found in the subgranular zone of the dg of the hippocampus 16 mo after intramarrow injection of the vector. |
2016-04-26 |
2023-08-13 |
rat |
| Donnahue Dennie, Jean-Pierre Louboutin, David S Straye. Migration of bone marrow progenitor cells in the adult brain of rats and rabbits. World journal of stem cells. vol 8. issue 4. 2016-04-26. PMID:27114746. |
inducing seizures by using kainic acid increased the number of bm progenitor cells transduced by sv40 vectors migrating to the hippocampus, and these cells were seen at earlier time points in the dg. |
2016-04-26 |
2023-08-13 |
rat |
| Dong Su. Endogenous neurogenic cell response in the mature mammalian brain following traumatic injury. Experimental neurology. vol 275 Pt 3. 2016-04-25. PMID:25936874. |
in the mature mammalian brain, new neurons are generated throughout life in the neurogenic regions of the subventricular zone (svz) and the dentate gyrus (dg) of the hippocampus. |
2016-04-25 |
2023-08-13 |
Not clear |
| Zülal Kaptan, Kadriye Akgün-Dar, Ayşegül Kapucu, Huri Dedeakayoğulları, Şule Batu, Gülay Üzü. Long term consequences on spatial learning-memory of low-calorie diet during adolescence in female rats; hippocampal and prefrontal cortex BDNF level, expression of NeuN and cell proliferation in dentate gyrus. Brain research. vol 1618. 2016-04-25. PMID:26072462. |
we hypothesized that feeding with as low as 15% low-calorie diet (lcd) during adolescence would increase hippocampal and prefrontal bdnf (brain-derived neurotrophic factor) levels, proliferative cells and neuron numbers in dentate gyrus (dg), thus positively affecting spatial memory in adulthood. |
2016-04-25 |
2023-08-13 |
rat |
| Zülal Kaptan, Kadriye Akgün-Dar, Ayşegül Kapucu, Huri Dedeakayoğulları, Şule Batu, Gülay Üzü. Long term consequences on spatial learning-memory of low-calorie diet during adolescence in female rats; hippocampal and prefrontal cortex BDNF level, expression of NeuN and cell proliferation in dentate gyrus. Brain research. vol 1618. 2016-04-25. PMID:26072462. |
pcna (proliferating cell nuclear antigen-cell proliferation marker) expressing cells and neun (neuronal nuclear antigen-neuron marker) expressing cells in hippocampus dg which are critically involved in memory were increased. |
2016-04-25 |
2023-08-13 |
rat |
| Kyoung Hoon Jeong, Dong-Seok Lee, Sang Ryong Ki. Effects of eugenol on granule cell dispersion in a mouse model of temporal lobe epilepsy. Epilepsy research. vol 115. 2016-04-25. PMID:26220380. |
these results suggest that eug may have beneficial effects in the treatment of epilepsy through its ability to inhibit gcd via suppression of ka-induced mtorc1 activation in the hippocampal dg in vivo. |
2016-04-25 |
2023-08-13 |
mouse |
| Swetha K Godavarthi, Parthanarayan Dey, Ankit Sharma, Nihar Ranjan Jan. Impaired adult hippocampal neurogenesis and its partial reversal by chronic treatment of fluoxetine in a mouse model of Angelman syndrome. Biochemical and biophysical research communications. vol 464. issue 4. 2016-04-25. PMID:26231800. |
although, the number of brdu and ki67-positive cell in the hippocampal dg region was nearly equal at early postnatal days among wild type and as mice, they were significantly reduced in adult as mice compared to wild type controls. |
2016-04-25 |
2023-08-13 |
mouse |