| Publication |
Sentence |
Publish Date |
Extraction Date |
Species |
| Niels Hansen, Denise Manahan-Vaugha. Locus Coeruleus Stimulation Facilitates Long-Term Depression in the Dentate Gyrus That Requires Activation of β-Adrenergic Receptors. Cerebral cortex (New York, N.Y. : 1991). vol 25. issue 7. 2016-02-19. PMID:24464942. |
the activation of locus coeruleus (lc) neurons by novel experience leads to noradrenaline release in the hippocampus at the level of the dentate gyrus (dg). |
2016-02-19 |
2023-08-12 |
rat |
| Woo Hyeun Kang, Barclay Morriso. Functional tolerance to mechanical deformation developed from organotypic hippocampal slice cultures. Biomechanics and modeling in mechanobiology. vol 14. issue 3. 2016-02-09. PMID:25236799. |
electrophysiological parameters associated with unstimulated spontaneous activity (neural event firing rate, duration, and magnitude), stimulated evoked responses (the maximum response [formula: see text], the stimulus current necessary for a half-maximal response [formula: see text], and the electrophysiological parameter m that is representative of firing uniformity), and paired-pulse responses (paired-pulse ratio at varying interstimulus intervals) were quantified for each hippocampal region (ca1, ca3, and dg). |
2016-02-09 |
2023-08-13 |
Not clear |
| Benjamin Adam Samuels, Christoph Anacker, Alice Hu, Marjorie R Levinstein, Anouchka Pickenhagen, Theodore Tsetsenis, Noelia Madroñal, Zoe R Donaldson, Liam John Drew, Alex Dranovsky, Cornelius T Gross, Kenji F Tanaka, René He. 5-HT1A receptors on mature dentate gyrus granule cells are critical for the antidepressant response. Nature neuroscience. vol 18. issue 11. 2016-02-09. PMID:26389840. |
adult hippocampal neurogenesis is necessary for some of the responses to ssris, but it is not known whether mature dentate gyrus granule cells (dg gcs) also contribute. |
2016-02-09 |
2023-08-13 |
mouse |
| Jay R Hoffman, Ishay Ostfeld, Jeffrey R Stout, Roger C Harris, Zeev Kaplan, Hagit Cohe. β-Alanine supplemented diets enhance behavioral resilience to stress exposure in an animal model of PTSD. Amino acids. vol 47. issue 6. 2016-02-04. PMID:25758106. |
bdnf expression in the ca1 and dg subregions of the hippocampus was lower (p < 0.05) in animals exposed and fed a normal diet compared to animals exposed and supplemented with ba, or animals unexposed. |
2016-02-04 |
2023-08-13 |
rat |
| Lida Tahmasebi, Alireza Komaki, Ruhollah Karamian, Siamak Shahidi, Abdolrahman Sarihi, Iraj Salehi, Ali Nikkha. The interactive role of cannabinoid and vanilloid systems in hippocampal synaptic plasticity in rats. European journal of pharmacology. vol 757. 2016-02-04. PMID:25843413. |
in this study, we examined the hippocampal effects of co-administrating win55-212-2 and capsaicin, which are cb1 and trpv1 agonists, respectively, on the induction of ltp in the dentate gyrus (dg) of rats. |
2016-02-04 |
2023-08-13 |
rat |
| Luis Federico Bátiz, Maite A Castro, Patricia V Burgos, Zahady D Velásquez, Rosa I Muñoz, Carlos A Lafourcade, Paulina Troncoso-Escudero, Ursula Wyneke. Exosomes as Novel Regulators of Adult Neurogenic Niches. Frontiers in cellular neuroscience. vol 9. 2016-02-02. PMID:26834560. |
adult neurogenesis has been convincingly demonstrated in two regions of the mammalian brain: the sub-granular zone (sgz) of the dentate gyrus (dg) in the hippocampus, and the sub-ventricular zone (svz) of the lateral ventricles (lv). |
2016-02-02 |
2023-08-13 |
Not clear |
| Kyung-Joo Seong, Hyun-Gwan Lee, Min Suk Kook, Hyun-Mi Ko, Ji-Yeon Jung, Won-Jae Ki. Epigallocatechin-3-gallate rescues LPS-impaired adult hippocampal neurogenesis through suppressing the TLR4-NF-κB signaling pathway in mice. The Korean journal of physiology & pharmacology : official journal of the Korean Physiological Society and the Korean Society of Pharmacology. vol 20. issue 1. 2016-01-25. PMID:26807022. |
adult hippocampal dentate granule neurons are generated from neural stem cells (nscs) in the mammalian brain, and the fate specification of adult nscs is precisely controlled by the local niches and environment, such as the subventricular zone (svz), dentate gyrus (dg), and toll-like receptors (tlrs). |
2016-01-25 |
2023-08-13 |
mouse |
| Nanthia A Suthana, Markus Donix, David R Wozny, Adam Bazih, Michael Jones, Robin M Heidemann, Robert Trampel, Arne D Ekstrom, Maria Scharf, Barbara Knowlton, Robert Turner, Susan Y Bookheime. High-resolution 7T fMRI of Human Hippocampal Subfields during Associative Learning. Journal of cognitive neuroscience. vol 27. issue 6. 2016-01-23. PMID:25514656. |
previous human fmri studies at 3 t have successfully detected differences in activation between hippocampal cornu ammonis (ca) field ca1, combined ca2, ca3, and dentate gyrus (dg) region (ca23dg), and the subiculum during associative memory tasks. |
2016-01-23 |
2023-08-13 |
human |
| Yasuhito Watanabe, Michaela K Müller, Jakob von Engelhardt, Rolf Sprengel, Peter H Seeburg, Hannah Monye. Age-Dependent Degeneration of Mature Dentate Gyrus Granule Cells Following NMDA Receptor Ablation. Frontiers in molecular neuroscience. vol 8. 2016-01-21. PMID:26793056. |
n-methyl-d-aspartate receptors (nmdars) in all hippocampal areas play an essential role in distinct processes of memory formation as well as in sustaining cell survival of postnatally generated neurons in the dentate gyrus (dg). |
2016-01-21 |
2023-08-13 |
mouse |
| Fenglei Chao, Lei Zhang, Yanmin Luo, Qian Xiao, Fulin Lv, Qi He, Chunni Zhou, Yi Zhang, Lin Jiang, Rong Jiang, Hengwei Gu, Yong Tan. Running Exercise Reduces Myelinated Fiber Loss in the Dentate Gyrus of the Hippocampus in APP/PS1 Transgenic Mice. Current Alzheimer research. vol 12. issue 4. 2016-01-20. PMID:25817255. |
to investigate the effect of running exercise on myelinated fibers in the dentate gyrus (dg) of the hippocampus during alzheimer's disease (ad), 6-month-old male app/ps1 transgenic mice were randomly assigned to control or running groups. |
2016-01-20 |
2023-08-13 |
mouse |
| Hirofumi Noguchi, Ayaka Kimura, Naoya Murao, Taito Matsuda, Masakazu Namihira, Kinichi Nakashim. Expression of DNMT1 in neural stem/precursor cells is critical for survival of newly generated neurons in the adult hippocampus. Neuroscience research. vol 95. 2016-01-19. PMID:25659757. |
adult neurogenesis persists throughout life in the dentate gyrus (dg) of the hippocampus, and its importance has been highlighted in hippocampus-dependent learning and memory. |
2016-01-19 |
2023-08-13 |
Not clear |
| Yuki Imoto, Toshihiko Kira, Mamiko Sukeno, Naoya Nishitani, Kazuki Nagayasu, Takayuki Nakagawa, Shuji Kaneko, Katsunori Kobayashi, Eri Segi-Nishid. Role of the 5-HT4 receptor in chronic fluoxetine treatment-induced neurogenic activity and granule cell dematuration in the dentate gyrus. Molecular brain. vol 8. 2016-01-19. PMID:25976618. |
chronic treatment with selective serotonin (5-ht) reuptake inhibitors (ssris) facilitates adult neurogenesis and reverses the state of maturation in mature granule cells (gcs) in the dentate gyrus (dg) of the hippocampus. |
2016-01-19 |
2023-08-13 |
Not clear |
| Chun-Sing Lam, George Lim Tipoe, Kwok-Fai So, Man-Lung Fun. Neuroprotective mechanism of Lycium barbarum polysaccharides against hippocampal-dependent spatial memory deficits in a rat model of obstructive sleep apnea. PloS one. vol 10. issue 2. 2016-01-18. PMID:25714473. |
in addition, redox-sensitive nuclear factor kappa b (nfКb) canonical pathway was activated with a translocation of nfКb members (p65, p50) and increased expression levels of nfКb-dependent inflammatory cytokines and mediator (tnfα, il-1β, cox-2); also, a significantly elevated level of er stress (grp78/bip, perk, chop) and autophagic flux in the hypoxic group, leading to neuronal apoptosis in hippocampal subfields (dg, ca1, ca3). |
2016-01-18 |
2023-08-13 |
rat |
| Evelin L Schaeffer, Wagner F Gatta. Chronic inhibition of brain phospholipase A2 in adult rats impairs the survival of newborn mature neurons in the hippocampus. Journal of neural transmission (Vienna, Austria : 1996). vol 122. issue 5. 2016-01-13. PMID:25160937. |
adult neurogenesis occurs in the hippocampal dentate gyrus (dg) and lateral ventricles, and includes cell proliferation and neuronal differentiation, maturation and survival. |
2016-01-13 |
2023-08-13 |
human |
| Evelin L Schaeffer, Wagner F Gatta. Chronic inhibition of brain phospholipase A2 in adult rats impairs the survival of newborn mature neurons in the hippocampus. Journal of neural transmission (Vienna, Austria : 1996). vol 122. issue 5. 2016-01-13. PMID:25160937. |
these findings show that chronic pla2 inhibition in adult rat hippocampus decreases the number of newborn mature neurons in the ventral dg (reflecting in the whole dg), perhaps by impairing neuronal maturation and survival, and suggest that pla2 inhibition reported in the hippocampus of alzheimer disease subjects might partly contribute to the neurogenic abnormalities found in the dg in this disease. |
2016-01-13 |
2023-08-13 |
human |
| Miranda C Staples, Airee Kim, Chitra D Mandya. Dendritic remodeling of hippocampal neurons is associated with altered NMDA receptor expression in alcohol dependent rats. Molecular and cellular neurosciences. vol 65. 2016-01-11. PMID:25769285. |
for this study, we investigated seven weeks of cie-induced morphological changes (dendritic complexity and dendritic spine density) of dentate gyrus (dg) granule cell neurons, ca3, and ca1 pyramidal neurons and the associated alterations in biochemical markers of synaptic plasticity and toxicity (nmda receptors and psd-95) in the hippocampus in ethanol-experienced wistar rats 3h (cie) and 21days (protracted abstinence) after the last ethanol vapor exposure. |
2016-01-11 |
2023-08-13 |
rat |
| Fábio G Teixeira, Miguel M Carvalho, Andreia Neves-Carvalho, Krishna M Panchalingam, Leo A Behie, Luísa Pinto, Nuno Sousa, António J Salgad. Secretome of mesenchymal progenitors from the umbilical cord acts as modulator of neural/glial proliferation and differentiation. Stem cell reviews and reports. vol 11. issue 2. 2016-01-08. PMID:25420577. |
in the present work, we aimed to assess if the secretome of hucpvcs is able to 1) induce the differentiation of human telencephalon neural precursor cells (htnpcs) in vitro, and 2) modulate neural/glial proliferation, differentiation and survival in the dentate gyrus (dg) of adult rat hippocampus. |
2016-01-08 |
2023-08-13 |
human |
| Ming-Shian Tsai, Meng-Larn Lee, Chun-Yun Chang, Hsiang-Hsuan Fan, I-Shing Yu, You-Tzung Chen, Jhih-Yi You, Chun-Yu Chen, Fang-Chia Chang, Jane H Hsiao, Olga Khorkova, Horng-Huei Liou, Yuchio Yanagawa, Li-Jen Lee, Shu-Wha Li. Functional and structural deficits of the dentate gyrus network coincide with emerging spontaneous seizures in an Scn1a mutant Dravet Syndrome model during development. Neurobiology of disease. vol 77. 2016-01-06. PMID:25725421. |
the nature and timing of changes caused by scn1a mutation in the hippocampal dentate gyrus (dg) network, a core area for gating major excitatory input to hippocampus and a classic epileptogenic zone, are not well known. |
2016-01-06 |
2023-08-13 |
mouse |
| Ming-Shian Tsai, Meng-Larn Lee, Chun-Yun Chang, Hsiang-Hsuan Fan, I-Shing Yu, You-Tzung Chen, Jhih-Yi You, Chun-Yu Chen, Fang-Chia Chang, Jane H Hsiao, Olga Khorkova, Horng-Huei Liou, Yuchio Yanagawa, Li-Jen Lee, Shu-Wha Li. Functional and structural deficits of the dentate gyrus network coincide with emerging spontaneous seizures in an Scn1a mutant Dravet Syndrome model during development. Neurobiology of disease. vol 77. 2016-01-06. PMID:25725421. |
during the same period, the het dg exhibited a greater reduction of nav1.1-expressing gabaergic neurons compared to other hippocampal areas. |
2016-01-06 |
2023-08-13 |
mouse |
| Zhen Zhang, Feng Gao, Xiaokui Kang, Jia Li, Litong Zhang, Wentao Dong, Zhangning Jin, Fan Li, Nannan Gao, Xinwang Cai, Shuyuan Yang, Jianning Zhang, Xinliang Ren, Xinyu Yan. Exploring the potential relationship between Notch pathway genes expression and their promoter methylation in mice hippocampal neurogenesis. Brain research bulletin. vol 113. 2016-01-04. PMID:25701255. |
we observed the expression of notch1, hes1 and ngn2 in hippocampal dg with qpcr, western blot and immunofluorescence staining. |
2016-01-04 |
2023-08-13 |
mouse |