| Publication |
Sentence |
Publish Date |
Extraction Date |
Species |
| A D Stan, S Ghose, C Zhao, K Hulsey, P Mihalakos, M Yanagi, S U Morris, J J Bartko, C Choi, C A Tamming. Magnetic resonance spectroscopy and tissue protein concentrations together suggest lower glutamate signaling in dentate gyrus in schizophrenia. Molecular psychiatry. vol 20. issue 4. 2015-12-09. PMID:24912493. |
in a mouse model with a dg knockout of the grin1 gene, we further confirmed that a selective decrease in dg glun1 is sufficient to decrease the glutamate concentrations in the whole hippocampus. |
2015-12-09 |
2023-08-13 |
mouse |
| A D Stan, S Ghose, C Zhao, K Hulsey, P Mihalakos, M Yanagi, S U Morris, J J Bartko, C Choi, C A Tamming. Magnetic resonance spectroscopy and tissue protein concentrations together suggest lower glutamate signaling in dentate gyrus in schizophrenia. Molecular psychiatry. vol 20. issue 4. 2015-12-09. PMID:24912493. |
these findings provide strong evidence implicating the excitatory system within hippocampus in the pathophysiology of schizophrenia, particularly indicating the dg as a site of pathology. |
2015-12-09 |
2023-08-13 |
mouse |
| Pen-Ning Yu, Min-Chi Hsiao, Dong Song, Charles Y Liu, Christi N Heck, David Millett, Theodore W Berge. Unstable periodic orbits in human epileptic hippocampal slices. Annual International Conference of the IEEE Engineering in Medicine and Biology Society. IEEE Engineering in Medicine and Biology Society. Annual International Conference. vol 2014. 2015-12-08. PMID:25571314. |
unstable periodic orbits (upos) are detected in the hippocampal slice at the dg area according to both the topological recurrence method and the periodic orbit transform method. |
2015-12-08 |
2023-08-13 |
human |
| Jürgen Berg, Manfred Roch, Jennifer Altschüler, Christine Winter, Anne Schwerk, Andreas Kurtz, Barbara Steine. Human adipose-derived mesenchymal stem cells improve motor functions and are neuroprotective in the 6-hydroxydopamine-rat model for Parkinson's disease when cultured in monolayer cultures but suppress hippocampal neurogenesis and hippocampal memory function when cultured in spheroids. Stem cell reviews and reports. vol 11. issue 1. 2015-12-04. PMID:25120226. |
in the present study we compared monolayer-cultured (amsc) and spheroid (smsc) msc following transplantation into the substantia nigra (sn) of 6-ohda lesioned rats regarding effects on the local microenvironment, degeneration of dopaminergic neurons, neurogenesis in the hippocampal dg as well as motor and memory function in the 6-ohda-rat model for pd. |
2015-12-04 |
2023-08-13 |
human |
| Jürgen Berg, Manfred Roch, Jennifer Altschüler, Christine Winter, Anne Schwerk, Andreas Kurtz, Barbara Steine. Human adipose-derived mesenchymal stem cells improve motor functions and are neuroprotective in the 6-hydroxydopamine-rat model for Parkinson's disease when cultured in monolayer cultures but suppress hippocampal neurogenesis and hippocampal memory function when cultured in spheroids. Stem cell reviews and reports. vol 11. issue 1. 2015-12-04. PMID:25120226. |
in contrast, smsc grafting induced an increased local microgliosis, decreased th levels in the sn and reduced numbers of newly generated cells in the dentate gyrus (dg) without yet affecting hippocampal learning and memory function. |
2015-12-04 |
2023-08-13 |
human |
| V Cuccioli, C Bueno, R Belvindrah, P-M Lledo, S Martine. Attractive action of FGF-signaling contributes to the postnatal developing hippocampus. Hippocampus. vol 25. issue 4. 2015-12-02. PMID:25348908. |
as development proceeds, new neurons are continuously produced, and this protracted neurogenesis is maintained throughout life in specialized germinative areas inside the telencephalon: the subventricular zone (svz) and the dentate gyrus (dg) of the hippocampus. |
2015-12-02 |
2023-08-13 |
Not clear |
| Phillip D Rivera, Ramya K Raghavan, Sanghee Yun, Sarah E Latchney, Mary-Katherin McGovern, Emily F García, Shari G Birnbaum, Amelia J Eisc. Retrieval of morphine-associated context induces cFos in dentate gyrus neurons. Hippocampus. vol 25. issue 4. 2015-12-02. PMID:25424867. |
this associative learning has a cellular correlate, as there are more cfos+ neurons in the hippocampal dentate gyrus (dg) after psychostimulant conditioned place preference (cpp) versus saline controls. |
2015-12-02 |
2023-08-13 |
mouse |
| Mohammad Torabi-Nami, Mohammad Nasehi, Mohammad-Reza Zarrindas. [Not Available]. EXCLI journal. vol 12. 2015-12-01. PMID:26622210. |
cpsr rats which underwent delayed brain excision following behavioral testing, showed deposition of the hpτ and revealed the least numerical density in the hippocampal dg neurons. |
2015-12-01 |
2023-08-13 |
rat |
| Mohammad Torabi-Nami, Mohammad Nasehi, Mohammad-Reza Zarrindas. [Not Available]. EXCLI journal. vol 12. 2015-12-01. PMID:26622210. |
meanwhile, ihc study revealed no aβ deposition in the hippocampal dg of all examined rats. |
2015-12-01 |
2023-08-13 |
rat |
| Mohammad Torabi-Nami, Mohammad Nasehi, Mohammad-Reza Zarrindas. [Not Available]. EXCLI journal. vol 12. 2015-12-01. PMID:26622210. |
interestingly, treatment with ifx, abrogated sleep restriction-induced cognitive decline, biochemical changes and the immunohistopathology in the hippocampal dg. |
2015-12-01 |
2023-08-13 |
rat |
| Mohammad Torabi-Nami, Mohammad Nasehi, Mohammad-Reza Zarrindas. [Not Available]. EXCLI journal. vol 12. 2015-12-01. PMID:26622210. |
taken together, our findings indicated that cpsr (the sd model mimicking shift work) induces not only cognitive and biochemical changes, but also pathology in the hippocampal dg. |
2015-12-01 |
2023-08-13 |
rat |
| Omamuyovwi M Ijomone, Polycarp U Nwoh. Nicotine inhibits hippocampal and striatal acetylcholinesterase activities, and demonstrates dual action on adult neuronal proliferation and maturation. Pathophysiology : the official journal of the International Society for Pathophysiology. vol 22. issue 4. 2015-11-30. PMID:26428579. |
the present study investigated the effects of nicotine on acetylcholinesterase (ache) activities in the hippocampus and striatum; and on immunoreactivity of certain neurogenic markers in the dentate gyrus (dg) of the hippocampus. |
2015-11-30 |
2023-08-13 |
Not clear |
| Klemencja Berghauzen-Maciejewska, Jadwiga Wardas, Barbara Kosmowska, Urszula Głowacka, Katarzyna Kuter, Krystyna Ossowsk. Alterations of BDNF and trkB mRNA expression in the 6-hydroxydopamine-induced model of preclinical stages of Parkinson's disease: an influence of chronic pramipexole in rats. PloS one. vol 10. issue 3. 2015-11-20. PMID:25739024. |
the lesion lowered the bdnf and trkb mrna levels in the hippocampus [ca1, ca3 and dentate gyrus (dg)] and amygdala (basolateral/lateral) as well as the bdnf mrna content in the habenula (medial/lateral). |
2015-11-20 |
2023-08-13 |
rat |
| Alexandra Antonides, Anne C Schoonderwoerd, Gabi Scholz, Brian M Berg, Rebecca E Nordquist, Franz Josef van der Staa. Pre-weaning dietary iron deficiency impairs spatial learning and memory in the cognitive holeboard task in piglets. Frontiers in behavioral neuroscience. vol 9. 2015-11-20. PMID:26578919. |
iron staining at necropsy at 12 weeks of age showed that id piglets had fewer iron-containing cells in hippocampal regions ca1 and dentate gyrus (dg). |
2015-11-20 |
2023-08-13 |
Not clear |
| Hui Qun Fu, Ting Yang, Wei Xiao, Long Fan, Yan Wu, Niccolò Terrando, Tian Long Wan. Prolonged neuroinflammation after lipopolysaccharide exposure in aged rats. PloS one. vol 9. issue 8. 2015-11-17. PMID:25170959. |
these changes associated with astrogliosis in the hippocampus dentate gyrus (dg), il-1β immunoreactivity and elevated nf-κb p65 expression up to day 30 post lps exposure. |
2015-11-17 |
2023-08-13 |
rat |
| Zhi Zhang, Henriette van Praa. Maternal immune activation differentially impacts mature and adult-born hippocampal neurons in male mice. Brain, behavior, and immunity. vol 45. 2015-11-17. PMID:25449671. |
the dentate gyrus (dg) of the hippocampus develops both before and after birth. |
2015-11-17 |
2023-08-13 |
mouse |
| U Sayin, E Hutchinson, M E Meyerand, T Sutul. Age-dependent long-term structural and functional effects of early-life seizures: evidence for a hippocampal critical period influencing plasticity in adulthood. Neuroscience. vol 288. 2015-10-29. PMID:25555928. |
seizures prior to p20 resulted in dti abnormalities in cc and hippocampus in the absence of gross cerebral atrophy, and increased paired-pulse inhibition (ppi) in the dentate gyrus (dg) at ⩾p95. |
2015-10-29 |
2023-08-13 |
rat |
| U Sayin, E Hutchinson, M E Meyerand, T Sutul. Age-dependent long-term structural and functional effects of early-life seizures: evidence for a hippocampal critical period influencing plasticity in adulthood. Neuroscience. vol 288. 2015-10-29. PMID:25555928. |
seizures after p30 induced a different pattern of dti abnormalities in the fimbria and hippocampus accompanied by gross cerebral atrophy with increases in lateral ventricular volume, as well as increased ppi in the dg at ⩾p95. |
2015-10-29 |
2023-08-13 |
rat |
| U Sayin, E Hutchinson, M E Meyerand, T Sutul. Age-dependent long-term structural and functional effects of early-life seizures: evidence for a hippocampal critical period influencing plasticity in adulthood. Neuroscience. vol 288. 2015-10-29. PMID:25555928. |
in contrast, seizures between p20 and p30 did not result in cerebral atrophy or significant imaging abnormalities in the hippocampus or white matter, but irreversibly decreased ppi in the dg compared to normal adult controls. |
2015-10-29 |
2023-08-13 |
rat |
| Na Li, Qun Liu, Xiao-Juan Li, Xiao-Hui Bai, Yue-Yun Liu, Hong-Bo Zhao, Zhong-Ye Jin, Yu-Xia Jing, Zhi-Yi Yan, Jia-Xu Che. TCM Formula Xiaoyaosan Decoction Improves Depressive-Like Behaviors in Rats with Type 2 Diabetes. Evidence-based complementary and alternative medicine : eCAM. vol 2015. 2015-10-28. PMID:26508978. |
in the h&e staining, changes were found predominately in the ca1 and dg subregions of the hippocampus. |
2015-10-28 |
2023-08-13 |
rat |