| Publication |
Sentence |
Publish Date |
Extraction Date |
Species |
| D H Kim, H E Lee, K J Kwon, S J Park, H Heo, Y Lee, J W Choi, C Y Shin, J H Ry. Early immature neuronal death initiates cerebral ischemia-induced neurogenesis in the dentate gyrus. Neuroscience. vol 284. 2015-12-22. PMID:25301746. |
throughout adulthood, neurons are continuously replaced by new cells in the dentate gyrus (dg) of the hippocampus, and this neurogenesis is increased by various neuronal injuries including ischemic stroke and seizure. |
2015-12-22 |
2023-08-13 |
mouse |
| D H Kim, H E Lee, K J Kwon, S J Park, H Heo, Y Lee, J W Choi, C Y Shin, J H Ry. Early immature neuronal death initiates cerebral ischemia-induced neurogenesis in the dentate gyrus. Neuroscience. vol 284. 2015-12-22. PMID:25301746. |
here, we investigated which signal(s) trigger(s) ischemia-induced cell proliferation and neurogenesis in the hippocampal dg region. |
2015-12-22 |
2023-08-13 |
mouse |
| Franco Ortiz, Rafael Gutiérre. Entorhinal cortex lesions result in adenosine-sensitive high frequency oscillations in the hippocampus. Experimental neurology. vol 271. 2015-12-22. PMID:26072121. |
entorhinal cortex (ec) projections to the hippocampus run along the perforant path and activate the hippocampal area ca3 and the dentate gyrus (dg), which, in turn, drives ca3. |
2015-12-22 |
2023-08-13 |
Not clear |
| Giovanna Maraula, Daniele Lana, Elisabetta Coppi, Francesca Gentile, Tommaso Mello, Alessia Melani, Andrea Galli, Maria Grazia Giovannini, Felicita Pedata, Anna Maria Puglies. The selective antagonism of P2X7 and P2Y1 receptors prevents synaptic failure and affects cell proliferation induced by oxygen and glucose deprivation in rat dentate gyrus. PloS one. vol 9. issue 12. 2015-12-21. PMID:25526634. |
the aim of this research was to determine the synaptic and proliferative response of the dg to severe oxygen and glucose deprivation (ogd) in acute rat hippocampal slices and to investigate the contribution of p2x7 and p2y1 receptor antagonism to recovery of synaptic activity after ogd. |
2015-12-21 |
2023-08-13 |
rat |
| Giovanna Maraula, Daniele Lana, Elisabetta Coppi, Francesca Gentile, Tommaso Mello, Alessia Melani, Andrea Galli, Maria Grazia Giovannini, Felicita Pedata, Anna Maria Puglies. The selective antagonism of P2X7 and P2Y1 receptors prevents synaptic failure and affects cell proliferation induced by oxygen and glucose deprivation in rat dentate gyrus. PloS one. vol 9. issue 12. 2015-12-21. PMID:25526634. |
extracellular field excitatory post-synaptic potentials (fepsps) in granule cells of the dg were recorded from rat hippocampal slices. |
2015-12-21 |
2023-08-13 |
rat |
| Patrícia Patrício, António Mateus-Pinheiro, Martin Irmler, Nuno D Alves, Ana R Machado-Santos, Mónica Morais, Joana S Correia, Michal Korostynski, Marcin Piechota, Rainer Stoffel, Johannes Beckers, João M Bessa, Osborne F X Almeida, Nuno Sousa, Luísa Pint. Differential and converging molecular mechanisms of antidepressants' action in the hippocampal dentate gyrus. Neuropsychopharmacology : official publication of the American College of Neuropsychopharmacology. vol 40. issue 2. 2015-12-18. PMID:25035085. |
neuroplastic changes in brain regions such as the hippocampal dentate gyrus (dg) accompany depression and its amelioration with ads. |
2015-12-18 |
2023-08-13 |
rat |
| Patrícia Patrício, António Mateus-Pinheiro, Martin Irmler, Nuno D Alves, Ana R Machado-Santos, Mónica Morais, Joana S Correia, Michal Korostynski, Marcin Piechota, Rainer Stoffel, Johannes Beckers, João M Bessa, Osborne F X Almeida, Nuno Sousa, Luísa Pint. Differential and converging molecular mechanisms of antidepressants' action in the hippocampal dentate gyrus. Neuropsychopharmacology : official publication of the American College of Neuropsychopharmacology. vol 40. issue 2. 2015-12-18. PMID:25035085. |
in this study, the unpredictable chronic mild stress (ucms) rat model of depression was used to determine the molecular mediators of chronic stress and the targets of four ads with different pharmacological profiles (fluoxetine, imipramine, tianeptine, and agomelatine) in the hippocampal dg. |
2015-12-18 |
2023-08-13 |
rat |
| N Osumi, N Guo, M Matsumata, K Yoshizak. Neurogenesis and sensorimotor gating: bridging a microphenotype and an endophenotype. Current molecular medicine. vol 15. issue 2. 2015-12-18. PMID:25732150. |
we noted impairments in the maturation of newborn neurons in the hippocampal dentate gyrus (dg) and gabaergic neurons in the hippocampus, which could be considered as microphenotypes associated with ppi defects. |
2015-12-18 |
2023-08-13 |
mouse |
| b' E Badowska-Szalewska, R Krawczyk, B Ludkiewicz, J Mory\\xc5\\x9. The effect of mild stress stimulation on the nerve growth factor (NGF) and tyrosine kinase receptor A (TrkA) immunoreactivity in the paraventricular nucleus (PVN) of the hypothalamus and hippocampus in aged vs. adult rats. Neuroscience. vol 290. 2015-12-15. PMID:25644424.' |
immunofluorescence staining was used to reveal the density of ngf and trka immunoreactive (ir) cells in the paraventricular nucleus (pvn) of the hypothalamus or hippocampal subfields ca1, ca3 and dentate gyrus (dg) in adult (postnatal day 90; p90) and aged (p720) rats. |
2015-12-15 |
2023-08-13 |
rat |
| Christina R Tyler, Alexander K Hafez, Elizabeth R Solomon, Andrea M Alla. Developmental exposure to 50 parts-per-billion arsenic influences histone modifications and associated epigenetic machinery in a region- and sex-specific manner in the adult mouse brain. Toxicology and applied pharmacology. vol 288. issue 1. 2015-12-15. PMID:26193056. |
we have previously demonstrated that exposure to a low level of arsenic (50ppb) during all three trimesters of fetal/neonatal development induces deficits in adult hippocampal neurogenesis in the dentate gyrus (dg), depressive-like symptoms, and alterations in gene expression in the adult mouse brain. |
2015-12-15 |
2023-08-13 |
mouse |
| Yucen Xia, Fangfang Qi, Juntao Zou, Junhua Yang, Zhibin Ya. Influenza vaccination during early pregnancy contributes to neurogenesis and behavioral function in offspring. Brain, behavior, and immunity. vol 42. 2015-12-14. PMID:25014010. |
quantification of brdu(+)/dcx(+) and brdu(+)/neun(+) cells in the dentate gyrus (dg) indicated an increase in the hippocampal neurogenesis of the pups born to both vaccinated mothers. |
2015-12-14 |
2023-08-13 |
mouse |
| B T J van Hagen, N P van Goethem, D C Lagatta, J Prickaert. The object pattern separation (OPS) task: a behavioral paradigm derived from the object recognition task. Behavioural brain research. vol 285. 2015-12-14. PMID:25446746. |
this task aims to measure spatial pattern separation per se, which utilizes memory processes centered in the dg and ca3 region of the hippocampus. |
2015-12-14 |
2023-08-13 |
mouse |
| A D Stan, S Ghose, C Zhao, K Hulsey, P Mihalakos, M Yanagi, S U Morris, J J Bartko, C Choi, C A Tamming. Magnetic resonance spectroscopy and tissue protein concentrations together suggest lower glutamate signaling in dentate gyrus in schizophrenia. Molecular psychiatry. vol 20. issue 4. 2015-12-09. PMID:24912493. |
the results show significantly lower glutamate concentrations in hippocampus in schizophrenia, an in vivo finding mirrored by lower glun1 protein levels selectively in the dentate gyrus (dg) in vitro. |
2015-12-09 |
2023-08-13 |
mouse |
| A D Stan, S Ghose, C Zhao, K Hulsey, P Mihalakos, M Yanagi, S U Morris, J J Bartko, C Choi, C A Tamming. Magnetic resonance spectroscopy and tissue protein concentrations together suggest lower glutamate signaling in dentate gyrus in schizophrenia. Molecular psychiatry. vol 20. issue 4. 2015-12-09. PMID:24912493. |
in a mouse model with a dg knockout of the grin1 gene, we further confirmed that a selective decrease in dg glun1 is sufficient to decrease the glutamate concentrations in the whole hippocampus. |
2015-12-09 |
2023-08-13 |
mouse |
| A D Stan, S Ghose, C Zhao, K Hulsey, P Mihalakos, M Yanagi, S U Morris, J J Bartko, C Choi, C A Tamming. Magnetic resonance spectroscopy and tissue protein concentrations together suggest lower glutamate signaling in dentate gyrus in schizophrenia. Molecular psychiatry. vol 20. issue 4. 2015-12-09. PMID:24912493. |
these findings provide strong evidence implicating the excitatory system within hippocampus in the pathophysiology of schizophrenia, particularly indicating the dg as a site of pathology. |
2015-12-09 |
2023-08-13 |
mouse |
| Pen-Ning Yu, Min-Chi Hsiao, Dong Song, Charles Y Liu, Christi N Heck, David Millett, Theodore W Berge. Unstable periodic orbits in human epileptic hippocampal slices. Annual International Conference of the IEEE Engineering in Medicine and Biology Society. IEEE Engineering in Medicine and Biology Society. Annual International Conference. vol 2014. 2015-12-08. PMID:25571314. |
unstable periodic orbits (upos) are detected in the hippocampal slice at the dg area according to both the topological recurrence method and the periodic orbit transform method. |
2015-12-08 |
2023-08-13 |
human |
| Jürgen Berg, Manfred Roch, Jennifer Altschüler, Christine Winter, Anne Schwerk, Andreas Kurtz, Barbara Steine. Human adipose-derived mesenchymal stem cells improve motor functions and are neuroprotective in the 6-hydroxydopamine-rat model for Parkinson's disease when cultured in monolayer cultures but suppress hippocampal neurogenesis and hippocampal memory function when cultured in spheroids. Stem cell reviews and reports. vol 11. issue 1. 2015-12-04. PMID:25120226. |
in the present study we compared monolayer-cultured (amsc) and spheroid (smsc) msc following transplantation into the substantia nigra (sn) of 6-ohda lesioned rats regarding effects on the local microenvironment, degeneration of dopaminergic neurons, neurogenesis in the hippocampal dg as well as motor and memory function in the 6-ohda-rat model for pd. |
2015-12-04 |
2023-08-13 |
human |
| Jürgen Berg, Manfred Roch, Jennifer Altschüler, Christine Winter, Anne Schwerk, Andreas Kurtz, Barbara Steine. Human adipose-derived mesenchymal stem cells improve motor functions and are neuroprotective in the 6-hydroxydopamine-rat model for Parkinson's disease when cultured in monolayer cultures but suppress hippocampal neurogenesis and hippocampal memory function when cultured in spheroids. Stem cell reviews and reports. vol 11. issue 1. 2015-12-04. PMID:25120226. |
in contrast, smsc grafting induced an increased local microgliosis, decreased th levels in the sn and reduced numbers of newly generated cells in the dentate gyrus (dg) without yet affecting hippocampal learning and memory function. |
2015-12-04 |
2023-08-13 |
human |
| V Cuccioli, C Bueno, R Belvindrah, P-M Lledo, S Martine. Attractive action of FGF-signaling contributes to the postnatal developing hippocampus. Hippocampus. vol 25. issue 4. 2015-12-02. PMID:25348908. |
as development proceeds, new neurons are continuously produced, and this protracted neurogenesis is maintained throughout life in specialized germinative areas inside the telencephalon: the subventricular zone (svz) and the dentate gyrus (dg) of the hippocampus. |
2015-12-02 |
2023-08-13 |
Not clear |
| Phillip D Rivera, Ramya K Raghavan, Sanghee Yun, Sarah E Latchney, Mary-Katherin McGovern, Emily F García, Shari G Birnbaum, Amelia J Eisc. Retrieval of morphine-associated context induces cFos in dentate gyrus neurons. Hippocampus. vol 25. issue 4. 2015-12-02. PMID:25424867. |
this associative learning has a cellular correlate, as there are more cfos+ neurons in the hippocampal dentate gyrus (dg) after psychostimulant conditioned place preference (cpp) versus saline controls. |
2015-12-02 |
2023-08-13 |
mouse |