| Publication |
Sentence |
Publish Date |
Extraction Date |
Species |
| Mathias Lundberg, Sophie Curbo, Hannes Bohman, Ingrid Agartz, Sven-Ove Ögren, Cesare Patrone, Shiva Mansour. Clozapine protects adult neural stem cells from ketamine-induced cell death in correlation with decreased apoptosis and autophagy. Bioscience reports. vol 40. issue 1. 2021-03-16. PMID:31919522. |
the antipsychotic drug clozapine was shown to counteract the observed decrease in brdu-labelled cells in hippocampal dentate gyrus (dg). |
2021-03-16 |
2023-08-13 |
mouse |
| Amir Segev, Masaya Yanagi, Daniel Scott, Sarah A Southcott, Jacob M Lister, Chunfeng Tan, Wei Li, Shari G Birnbaum, Saïd Kourrich, Carol A Tamming. Reduced GluN1 in mouse dentate gyrus is associated with CA3 hyperactivity and psychosis-like behaviors. Molecular psychiatry. vol 25. issue 11. 2021-03-15. PMID:30038231. |
in this study, we used a subfield-specific glun1 knockout mouse with a disease-like molecular perturbation expressed only in hippocampal dentate gyrus (dg) and assessed its association with hippocampal physiology and psychosis-like behaviors. |
2021-03-15 |
2023-08-13 |
mouse |
| Hao Wang, Juntao Liu, Zeying Lu, Yuchuan Dai, Jingyu Xie, Shengwei Xu, Yilin Song, Guihua Xiao, Fei Gao, Lina Qu, Xinxia Ca. Implanted multichannel microelectrode array for simultaneous electrophysiological signal detection of hippocampal CA1 and DG neurons of simulated microgravity rats. Biochemical and biophysical research communications. vol 531. issue 3. 2021-03-10. PMID:32800539. |
in these experiments, microelectrode array was inserted into normal, 28-day tail suspension model, and 3-day recovered after modulation rats to record electrophysiological signals in the ca1 and dg regions of the hippocampus. |
2021-03-10 |
2023-08-13 |
rat |
| Scott D Sawchuk, Hannah M O Reid, Katie J Neale, James Shin, Brian R Christi. Effects of Ethanol on Synaptic Plasticity and NMDA Currents in the Juvenile Rat Dentate Gyrus. Brain plasticity (Amsterdam, Netherlands). vol 6. issue 1. 2021-03-10. PMID:33680851. |
we examined how acute ethanol (etoh) exposure affects long term depression (ltd) in the dentate gyrus (dg) of the hippocampus in juvenile rats. |
2021-03-10 |
2023-08-13 |
rat |
| Kyohei Kin, Takao Yasuhara, Masahiro Kameda, Yousuke Tomita, Michiari Umakoshi, Ken Kuwahara, Ittetsu Kin, Naoya Kidani, Jun Morimoto, Mihoko Okazaki, Tatsuya Sasaki, Naoki Tajiri, Cesario V Borlongan, Isao Dat. Cell encapsulation enhances antidepressant effect of the mesenchymal stem cells and counteracts depressive-like behavior of treatment-resistant depressed rats. Molecular psychiatry. vol 25. issue 6. 2021-03-09. PMID:30108315. |
the implantation of encapsulated mscs (emscs) into the lateral ventricle counteracted depressive-like behavior and enhanced the endogenous neurogenesis in the subventricular zone (svz) and the dentate gyrus (dg) of the hippocampus, whereas the implantation of mscs without encapsulation or the implantation of emscs into the striatum did not show such ameliorative effects. |
2021-03-09 |
2023-08-13 |
rat |
| Yotam Sagi, Lucian Medrihan, Katia George, Miles Barney, Kathryn A McCabe, Paul Greengar. Emergence of 5-HT5A signaling in parvalbumin neurons mediates delayed antidepressant action. Molecular psychiatry. vol 25. issue 6. 2021-03-09. PMID:30804492. |
the behavioral response to antidepressants is closely associated with physiological changes in the function of neurons in the hippocampal dentate gyrus (dg). |
2021-03-09 |
2023-08-13 |
mouse |
| Ricardo Gómez-Oliva, Noelia Geribaldi-Doldán, Samuel Domínguez-García, Livia Carrascal, Cristina Verástegui, Pedro Nunez-Abades, Carmen Castr. Vitamin D deficiency as a potential risk factor for accelerated aging, impaired hippocampal neurogenesis and cognitive decline: a role for Wnt/β-catenin signaling. Aging. vol 12. issue 13. 2021-03-08. PMID:32554862. |
neurogenesis occurs in the adult brain in neurogenic regions, such as the dentate gyrus of the hippocampus (dg). |
2021-03-08 |
2023-08-13 |
Not clear |
| John T Madden, Shannon M Thompson, Christy M Magcalas, Jennifer L Wagner, Derek A Hamilton, Daniel D Savage, Benjamin J Clark, Nathan S Pentkowsk. Moderate prenatal alcohol exposure reduces parvalbumin expressing GABAergic interneurons in the dorsal hippocampus of adult male and female rat offspring. Neuroscience letters. vol 718. 2021-03-01. PMID:31874217. |
to explore the effects of moderate pae on gabaergic interneuron expression, this study used a rat model of moderate pae to examine the effects of pae on parvalbumin (parv)-positive cells in fields ca1, ca3 and the dentate gyrus (dg) of the dorsal hippocampus (dhc). |
2021-03-01 |
2023-08-13 |
rat |
| Hiroko Nakai, Ryosuke Tsumagari, Kenta Maruo, Akio Nakashima, Ushio Kikkawa, Shuji Ueda, Minoru Yamanoue, Naoaki Saito, Nobuyuki Takei, Yasuhito Shira. mTORC1 is involved in DGKβ-induced neurite outgrowth and spinogenesis. Neurochemistry international. vol 134. 2021-02-23. PMID:31891737. |
diacylglycerol kinase β (dgkβ) is an enzyme converting dg to phosphatidic acid (pa) and is specifically expressed in neurons, especially those in the cerebral cortex, hippocampus and striatum. |
2021-02-23 |
2023-08-13 |
human |
| Guang-Xiao Ni, Ce Liang, Jing Wang, Chun-Qiao Duan, Pu Wang, Ya-Li Wan. Astragaloside IV improves neurobehavior and promotes hippocampal neurogenesis in MCAO rats though BDNF-TrkB signaling pathway. Biomedicine & pharmacotherapy = Biomedecine & pharmacotherapie. vol 130. 2021-02-23. PMID:32682983. |
the current study was aimed to evaluate the influence of ast on neurogenesis in hippocampal dentate gyrus (dg) of mcao rats and to explore the possible mechanisms. |
2021-02-23 |
2023-08-13 |
rat |
| Soichiro Nakahara, Megumi Adachi, Hiroyuki Ito, Mitsuyuki Matsumoto, Katsunori Tajinda, Theo G M van Er. Hippocampal Pathophysiology: Commonality Shared by Temporal Lobe Epilepsy and Psychiatric Disorders. Neuroscience journal. vol 2018. 2021-02-18. PMID:29610762. |
in the present review, we overview abnormal network connectivity between the dentate gyrus (dg) and the cornus ammonis area 3 (ca3) subregions of the hippocampus relative to the induction of epilepsy and schizophrenia. |
2021-02-18 |
2023-08-13 |
Not clear |
| Daniel García-Pérez, Maria Victoria Milané. Role of glucocorticoids on noradrenergic and dopaminergic neurotransmission within the basolateral amygdala and dentate gyrus during morphine withdrawal place aversion. Addiction biology. vol 25. issue 2. 2021-02-16. PMID:30784175. |
limbic structures, such as the basolateral amygdala (bla) and the dentate gyrus (dg) of the hippocampus, play a crucial role in the negative affective component of morphine withdrawal. |
2021-02-16 |
2023-08-13 |
Not clear |
| Hyeonho Kim, Hyeji Jung, Hyunsu Jung, Seok-Kyu Kwon, Jaewon Ko, Ji Won U. The small GTPase ARF6 regulates GABAergic synapse development. Molecular brain. vol 13. issue 1. 2021-02-12. PMID:31907062. |
arf6 kd also reduced gabaergic synaptic density in the mouse hippocampal dentate gyrus (dg) region. |
2021-02-12 |
2023-08-13 |
mouse |
| Qi Zhong, Yufeng Zou, Hongchao Liu, Ting Chen, Feng Zheng, Yifei Huang, Chang Chen, Zongze Zhan. Toll-like receptor 4 deficiency ameliorates β2-microglobulin induced age-related cognition decline due to neuroinflammation in mice. Molecular brain. vol 13. issue 1. 2021-02-12. PMID:32059688. |
the results showed that wt mice received b2m in the dg exhibited age-related cognitive declines, increased tlr4 mrna expression and high levels of interleukin-1β (il-1β), tumor necrosis factor-alpha (tnf-α) and apoptotic neuronal death in the hippocampus, which were partially attenuated in tlr4-ko mice. |
2021-02-12 |
2023-08-13 |
mouse |
| Wenbiao Xiao, Zhiquan Yang, Xiaoxin Yan, Li Feng, Lili Long, Tian Tu, Na Deng, Wenjuan Chen, Bo Xiao, Hongyu Long, Yi Zen. iTRAQ-Based Proteomic Analysis of Dentate Gyrus in Temporal Lobe Epilepsy With Hippocampal Sclerosis. Frontiers in neurology. vol 11. 2021-02-12. PMID:33569037. |
the dentate gyrus (dg), one specific hippocampal subarea, structural and functional changes imply a key involvement of the dg in the development of tle. |
2021-02-12 |
2023-08-13 |
Not clear |
| Wenbiao Xiao, Zhiquan Yang, Xiaoxin Yan, Li Feng, Lili Long, Tian Tu, Na Deng, Wenjuan Chen, Bo Xiao, Hongyu Long, Yi Zen. iTRAQ-Based Proteomic Analysis of Dentate Gyrus in Temporal Lobe Epilepsy With Hippocampal Sclerosis. Frontiers in neurology. vol 11. 2021-02-12. PMID:33569037. |
in this study, a isobaric tags for relative and absolute quantitation (itraq)-based quantitative proteomic technique was performed for the analysis of hippocampal dg obtained from patients with tle-hs compared to control samples obtained from autopsy. |
2021-02-12 |
2023-08-13 |
Not clear |
| Huagang Li, Dong Sun, Dongwei Lu, Junjian Zhang, Junjie Zen. Low Hippocampal Dentate Gyrus Volume Associated With Hypertension-Related Cognitive Impairment. American journal of Alzheimer's disease and other dementias. vol 35. 2021-02-10. PMID:33043683. |
higher coefficient of variation (cv) of daytime sbp was significantly associated with lower volume of the left cornu ammonis 4 and dentate gyrus (dg) region. |
2021-02-10 |
2023-08-13 |
human |
| Annakarina Mundorf, Stefanie Rommel, Malte Verheyen, Evanthia Mergia, Marcus Peters, Nadja Freun. Cigarette smoke exposure has region-specific effects on GDAP1 expression in mouse hippocampus. Psychiatry research. vol 289. 2021-02-01. PMID:32438208. |
three randomized frames for dentate gyrus (dg) and three for cornu ammonis region 1 (ca1) were used to count gdap1. |
2021-02-01 |
2023-08-13 |
mouse |
| Roberto Valcárcel-Martín, Soraya Martín-Suárez, Teresa Muro-García, Oier Pastor-Alonso, Fernando Rodríguez de Fonseca, Guillermo Estivill-Torrús, Juan Manuel Encina. Lysophosphatidic Acid Receptor 1 Specifically Labels Seizure-Induced Hippocampal Reactive Neural Stem Cells and Regulates Their Division. Frontiers in neuroscience. vol 14. 2021-01-28. PMID:32922255. |
a population of neural stem cells (nscs) dwelling in the dentate gyrus (dg) is able to generate neurons throughout adult life in the hippocampus of most mammals. |
2021-01-28 |
2023-08-13 |
Not clear |
| Heekyung Lee, Douglas GoodSmith, James J Knieri. Parallel processing streams in the hippocampus. Current opinion in neurobiology. vol 64. 2021-01-27. PMID:32502734. |
however, recent evidence of functional heterogeneity along the ca3 transverse axis of the hippocampus suggests that the dg and proximal ca3 work as a functional unit for pattern separation, while distal ca3 forms an autoassociative network for pattern completion. |
2021-01-27 |
2023-08-13 |
Not clear |