| Publication |
Sentence |
Publish Date |
Extraction Date |
Species |
| John T Madden, Shannon M Thompson, Christy M Magcalas, Jennifer L Wagner, Derek A Hamilton, Daniel D Savage, Benjamin J Clark, Nathan S Pentkowsk. Moderate prenatal alcohol exposure reduces parvalbumin expressing GABAergic interneurons in the dorsal hippocampus of adult male and female rat offspring. Neuroscience letters. vol 718. 2021-03-01. PMID:31874217. |
to explore the effects of moderate pae on gabaergic interneuron expression, this study used a rat model of moderate pae to examine the effects of pae on parvalbumin (parv)-positive cells in fields ca1, ca3 and the dentate gyrus (dg) of the dorsal hippocampus (dhc). |
2021-03-01 |
2023-08-13 |
rat |
| Hiroko Nakai, Ryosuke Tsumagari, Kenta Maruo, Akio Nakashima, Ushio Kikkawa, Shuji Ueda, Minoru Yamanoue, Naoaki Saito, Nobuyuki Takei, Yasuhito Shira. mTORC1 is involved in DGKβ-induced neurite outgrowth and spinogenesis. Neurochemistry international. vol 134. 2021-02-23. PMID:31891737. |
diacylglycerol kinase β (dgkβ) is an enzyme converting dg to phosphatidic acid (pa) and is specifically expressed in neurons, especially those in the cerebral cortex, hippocampus and striatum. |
2021-02-23 |
2023-08-13 |
human |
| Guang-Xiao Ni, Ce Liang, Jing Wang, Chun-Qiao Duan, Pu Wang, Ya-Li Wan. Astragaloside IV improves neurobehavior and promotes hippocampal neurogenesis in MCAO rats though BDNF-TrkB signaling pathway. Biomedicine & pharmacotherapy = Biomedecine & pharmacotherapie. vol 130. 2021-02-23. PMID:32682983. |
the current study was aimed to evaluate the influence of ast on neurogenesis in hippocampal dentate gyrus (dg) of mcao rats and to explore the possible mechanisms. |
2021-02-23 |
2023-08-13 |
rat |
| Soichiro Nakahara, Megumi Adachi, Hiroyuki Ito, Mitsuyuki Matsumoto, Katsunori Tajinda, Theo G M van Er. Hippocampal Pathophysiology: Commonality Shared by Temporal Lobe Epilepsy and Psychiatric Disorders. Neuroscience journal. vol 2018. 2021-02-18. PMID:29610762. |
in the present review, we overview abnormal network connectivity between the dentate gyrus (dg) and the cornus ammonis area 3 (ca3) subregions of the hippocampus relative to the induction of epilepsy and schizophrenia. |
2021-02-18 |
2023-08-13 |
Not clear |
| Daniel García-Pérez, Maria Victoria Milané. Role of glucocorticoids on noradrenergic and dopaminergic neurotransmission within the basolateral amygdala and dentate gyrus during morphine withdrawal place aversion. Addiction biology. vol 25. issue 2. 2021-02-16. PMID:30784175. |
limbic structures, such as the basolateral amygdala (bla) and the dentate gyrus (dg) of the hippocampus, play a crucial role in the negative affective component of morphine withdrawal. |
2021-02-16 |
2023-08-13 |
Not clear |
| Hyeonho Kim, Hyeji Jung, Hyunsu Jung, Seok-Kyu Kwon, Jaewon Ko, Ji Won U. The small GTPase ARF6 regulates GABAergic synapse development. Molecular brain. vol 13. issue 1. 2021-02-12. PMID:31907062. |
arf6 kd also reduced gabaergic synaptic density in the mouse hippocampal dentate gyrus (dg) region. |
2021-02-12 |
2023-08-13 |
mouse |
| Qi Zhong, Yufeng Zou, Hongchao Liu, Ting Chen, Feng Zheng, Yifei Huang, Chang Chen, Zongze Zhan. Toll-like receptor 4 deficiency ameliorates β2-microglobulin induced age-related cognition decline due to neuroinflammation in mice. Molecular brain. vol 13. issue 1. 2021-02-12. PMID:32059688. |
the results showed that wt mice received b2m in the dg exhibited age-related cognitive declines, increased tlr4 mrna expression and high levels of interleukin-1β (il-1β), tumor necrosis factor-alpha (tnf-α) and apoptotic neuronal death in the hippocampus, which were partially attenuated in tlr4-ko mice. |
2021-02-12 |
2023-08-13 |
mouse |
| Wenbiao Xiao, Zhiquan Yang, Xiaoxin Yan, Li Feng, Lili Long, Tian Tu, Na Deng, Wenjuan Chen, Bo Xiao, Hongyu Long, Yi Zen. iTRAQ-Based Proteomic Analysis of Dentate Gyrus in Temporal Lobe Epilepsy With Hippocampal Sclerosis. Frontiers in neurology. vol 11. 2021-02-12. PMID:33569037. |
the dentate gyrus (dg), one specific hippocampal subarea, structural and functional changes imply a key involvement of the dg in the development of tle. |
2021-02-12 |
2023-08-13 |
Not clear |
| Wenbiao Xiao, Zhiquan Yang, Xiaoxin Yan, Li Feng, Lili Long, Tian Tu, Na Deng, Wenjuan Chen, Bo Xiao, Hongyu Long, Yi Zen. iTRAQ-Based Proteomic Analysis of Dentate Gyrus in Temporal Lobe Epilepsy With Hippocampal Sclerosis. Frontiers in neurology. vol 11. 2021-02-12. PMID:33569037. |
in this study, a isobaric tags for relative and absolute quantitation (itraq)-based quantitative proteomic technique was performed for the analysis of hippocampal dg obtained from patients with tle-hs compared to control samples obtained from autopsy. |
2021-02-12 |
2023-08-13 |
Not clear |
| Huagang Li, Dong Sun, Dongwei Lu, Junjian Zhang, Junjie Zen. Low Hippocampal Dentate Gyrus Volume Associated With Hypertension-Related Cognitive Impairment. American journal of Alzheimer's disease and other dementias. vol 35. 2021-02-10. PMID:33043683. |
higher coefficient of variation (cv) of daytime sbp was significantly associated with lower volume of the left cornu ammonis 4 and dentate gyrus (dg) region. |
2021-02-10 |
2023-08-13 |
human |
| Annakarina Mundorf, Stefanie Rommel, Malte Verheyen, Evanthia Mergia, Marcus Peters, Nadja Freun. Cigarette smoke exposure has region-specific effects on GDAP1 expression in mouse hippocampus. Psychiatry research. vol 289. 2021-02-01. PMID:32438208. |
three randomized frames for dentate gyrus (dg) and three for cornu ammonis region 1 (ca1) were used to count gdap1. |
2021-02-01 |
2023-08-13 |
mouse |
| Roberto Valcárcel-Martín, Soraya Martín-Suárez, Teresa Muro-García, Oier Pastor-Alonso, Fernando Rodríguez de Fonseca, Guillermo Estivill-Torrús, Juan Manuel Encina. Lysophosphatidic Acid Receptor 1 Specifically Labels Seizure-Induced Hippocampal Reactive Neural Stem Cells and Regulates Their Division. Frontiers in neuroscience. vol 14. 2021-01-28. PMID:32922255. |
a population of neural stem cells (nscs) dwelling in the dentate gyrus (dg) is able to generate neurons throughout adult life in the hippocampus of most mammals. |
2021-01-28 |
2023-08-13 |
Not clear |
| Heekyung Lee, Douglas GoodSmith, James J Knieri. Parallel processing streams in the hippocampus. Current opinion in neurobiology. vol 64. 2021-01-27. PMID:32502734. |
however, recent evidence of functional heterogeneity along the ca3 transverse axis of the hippocampus suggests that the dg and proximal ca3 work as a functional unit for pattern separation, while distal ca3 forms an autoassociative network for pattern completion. |
2021-01-27 |
2023-08-13 |
Not clear |
| Lyles R Clark, Sanghee Yun, Nana K Acquah, Priya L Kumar, Hannah E Metheny, Rikley C C Paixao, Akivas S Cohen, Amelia J Eisc. Mild Traumatic Brain Injury Induces Transient, Sequential Increases in Proliferation, Neuroblasts/Immature Neurons, and Cell Survival: A Time Course Study in the Male Mouse Dentate Gyrus. Frontiers in neuroscience. vol 14. 2021-01-26. PMID:33488351. |
mtbis can impair hippocampal-based functions such as memory and cause network hyperexcitability of the dentate gyrus (dg), a key entry point to hippocampal circuitry. |
2021-01-26 |
2023-08-13 |
mouse |
| Lyles R Clark, Sanghee Yun, Nana K Acquah, Priya L Kumar, Hannah E Metheny, Rikley C C Paixao, Akivas S Cohen, Amelia J Eisc. Mild Traumatic Brain Injury Induces Transient, Sequential Increases in Proliferation, Neuroblasts/Immature Neurons, and Cell Survival: A Time Course Study in the Male Mouse Dentate Gyrus. Frontiers in neuroscience. vol 14. 2021-01-26. PMID:33488351. |
one candidate for mediating mtbi-induced hippocampal cognitive and physiological dysfunction is injury-induced changes in the process of dg neurogenesis. |
2021-01-26 |
2023-08-13 |
mouse |
| Lyles R Clark, Sanghee Yun, Nana K Acquah, Priya L Kumar, Hannah E Metheny, Rikley C C Paixao, Akivas S Cohen, Amelia J Eisc. Mild Traumatic Brain Injury Induces Transient, Sequential Increases in Proliferation, Neuroblasts/Immature Neurons, and Cell Survival: A Time Course Study in the Male Mouse Dentate Gyrus. Frontiers in neuroscience. vol 14. 2021-01-26. PMID:33488351. |
here we utilized a clinically relevant rodent model of mtbi (lateral fluid percussion injury, lfpi), gold-standard markers and quantification of the neurogenesis process, and three time points post-injury to generate a comprehensive picture of how mtbi affects adult hippocampal dg neurogenesis. |
2021-01-26 |
2023-08-13 |
mouse |
| Julieta Correa, Santiago Ronchetti, Florencia Labombarda, Alejandro F De Nicola, Luciana Pietraner. Activation of the G Protein-Coupled Estrogen Receptor (GPER) Increases Neurogenesis and Ameliorates Neuroinflammation in the Hippocampus of Male Spontaneously Hypertensive Rats. Cellular and molecular neurobiology. vol 40. issue 5. 2021-01-25. PMID:31784921. |
abnormalities of the hippocampus of shr include decreased neurogenesis in the dentate gyrus (dg), partial loss of neurons in the hilus of the dg, micro and astrogliosis and inflammation. |
2021-01-25 |
2023-08-13 |
rat |
| Julieta Correa, Santiago Ronchetti, Florencia Labombarda, Alejandro F De Nicola, Luciana Pietraner. Activation of the G Protein-Coupled Estrogen Receptor (GPER) Increases Neurogenesis and Ameliorates Neuroinflammation in the Hippocampus of Male Spontaneously Hypertensive Rats. Cellular and molecular neurobiology. vol 40. issue 5. 2021-01-25. PMID:31784921. |
we found that g1 activation of gper increased dcx+ cells in the dg and reduced gfap+ astrogliosis and iba1+ microgliosis in the ca1 region of hippocampus. |
2021-01-25 |
2023-08-13 |
rat |
| Amanda M Canto, Alexandre H B Matos, Alexandre B Godoi, André S Vieira, Beatriz B Aoyama, Cristiane S Rocha, Barbara Henning, Benilton S Carvalho, Vinicius D B Pascoal, Diogo F T Veiga, Rovilson Gilioli, Fernando Cendes, Iscia Lopes-Cende. Multi-omics analysis suggests enhanced epileptogenesis in the Cornu Ammonis 3 of the pilocarpine model of mesial temporal lobe epilepsy. Hippocampus. vol 31. issue 2. 2021-01-25. PMID:33037862. |
we used a multi-omics approach to determine the profile of transcript and protein expression in the dorsal and ventral hippocampal dentate gyrus (dg) and cornu ammonis 3 (ca3) in an animal model of mtle induced by pilocarpine. |
2021-01-25 |
2023-08-13 |
rat |
| Amanda M Canto, Alexandre H B Matos, Alexandre B Godoi, André S Vieira, Beatriz B Aoyama, Cristiane S Rocha, Barbara Henning, Benilton S Carvalho, Vinicius D B Pascoal, Diogo F T Veiga, Rovilson Gilioli, Fernando Cendes, Iscia Lopes-Cende. Multi-omics analysis suggests enhanced epileptogenesis in the Cornu Ammonis 3 of the pilocarpine model of mesial temporal lobe epilepsy. Hippocampus. vol 31. issue 2. 2021-01-25. PMID:33037862. |
our results indicate differences in the transcriptomic and proteomic profiles among the dg and the ca3 subfields of the hippocampus. |
2021-01-25 |
2023-08-13 |
rat |