| Publication |
Sentence |
Publish Date |
Extraction Date |
Species |
| Garrett Smith, Asha Rani, Ashok Kumar, Jolie Barter, Thomas C Foste. Hippocampal Subregion Transcriptomic Profiles Reflect Strategy Selection during Cognitive Aging. The Journal of neuroscience : the official journal of the Society for Neuroscience. vol 40. issue 25. 2020-10-26. PMID:32376783. |
age-related cognitive impairments are associated with differentially expressed genes (degs) linked to defined neural systems; however, studies examining multiple regions of the hippocampus fail to find links between behavior and transcription in the dentate gyrus (dg). |
2020-10-26 |
2023-08-13 |
rat |
| Garrett Smith, Asha Rani, Ashok Kumar, Jolie Barter, Thomas C Foste. Hippocampal Subregion Transcriptomic Profiles Reflect Strategy Selection during Cognitive Aging. The Journal of neuroscience : the official journal of the Society for Neuroscience. vol 40. issue 25. 2020-10-26. PMID:32376783. |
mrna sequencing of hippocampal subregions indicated degs in the dg of middle-age rats, linked to synaptic function and neurogenesis, correlated with beacon discrimination performance, suggesting that senescence of the dg underlies the impairment. |
2020-10-26 |
2023-08-13 |
rat |
| Haijun Zhu, Chong Ding, Yang Li, Guizhi X. [Repetitive transcranial magnetic stimulation significantly improves cognitive impairment and neuronal excitability during aging in mice]. Sheng wu yi xue gong cheng xue za zhi = Journal of biomedical engineering = Shengwu yixue gongchengxue zazhi. vol 37. issue 3. 2020-10-23. PMID:32597078. |
whole-cell patch clamp technique was used to record and analyze resting membrane potential, action potential (ap), and related electrical properties of ap of hippocampal dentate gyrus (dg) granule neurons. |
2020-10-23 |
2023-08-13 |
mouse |
| Justin J Botterill, Yi-Ling Lu, John J LaFrancois, Hannah L Bernstein, David Alcantara-Gonzalez, Swati Jain, Paige Leary, Helen E Scharfma. An Excitatory and Epileptogenic Effect of Dentate Gyrus Mossy Cells in a Mouse Model of Epilepsy. Cell reports. vol 29. issue 9. 2020-10-20. PMID:31775052. |
the sparse activity of hippocampal dentate gyrus (dg) granule cells (gcs) is thought to be critical for cognition and behavior, whereas excessive dg activity may contribute to disorders such as temporal lobe epilepsy (tle). |
2020-10-20 |
2023-08-13 |
mouse |
| Deependra Kumar, Iyo Koyanagi, Alvaro Carrier-Ruiz, Pablo Vergara, Sakthivel Srinivasan, Yuki Sugaya, Masatoshi Kasuya, Tzong-Shiue Yu, Kaspar E Vogt, Masafumi Muratani, Takaaki Ohnishi, Sima Singh, Catia M Teixeira, Yoan Chérasse, Toshie Naoi, Szu-Han Wang, Pimpimon Nondhalee, Boran A H Osman, Naoko Kaneko, Kazunobu Sawamoto, Steven G Kernie, Takeshi Sakurai, Thomas J McHugh, Masanobu Kano, Masashi Yanagisawa, Masanori Sakaguch. Sparse Activity of Hippocampal Adult-Born Neurons during REM Sleep Is Necessary for Memory Consolidation. Neuron. vol 107. issue 3. 2020-10-19. PMID:32502462. |
within the mammalian hippocampus, the dentate gyrus (dg) has the unique characteristic of exhibiting neurogenesis persisting into adulthood. |
2020-10-19 |
2023-08-13 |
Not clear |
| Bijurika Nandi, Peter Swiatek, Bernat Kocsis, Mingzhou Din. Inferring the direction of rhythmic neural transmission via inter-regional phase-amplitude coupling (ir-PAC). Scientific reports. vol 9. issue 1. 2020-10-16. PMID:31061409. |
we tested the hypothesis on theta-band long range communications between hippocampus and prefrontal cortex (pfc) and theta-band short range communications between dentate gyrus (dg) and the ammon's horn (ca1) within the hippocampus. |
2020-10-16 |
2023-08-13 |
Not clear |
| Bijurika Nandi, Peter Swiatek, Bernat Kocsis, Mingzhou Din. Inferring the direction of rhythmic neural transmission via inter-regional phase-amplitude coupling (ir-PAC). Scientific reports. vol 9. issue 1. 2020-10-16. PMID:31061409. |
the ground truth was provided by the known anatomical connections predicting hippocampus → pfc and dg → ca1, i.e., theta transmission is unidirectional in both cases: from hippocampus to pfc and from dg to ca1 along the tri-synaptic pathway within hippocampus. |
2020-10-16 |
2023-08-13 |
Not clear |
| Bijurika Nandi, Peter Swiatek, Bernat Kocsis, Mingzhou Din. Inferring the direction of rhythmic neural transmission via inter-regional phase-amplitude coupling (ir-PAC). Scientific reports. vol 9. issue 1. 2020-10-16. PMID:31061409. |
we found that (1) hippocampal high-gamma amplitude was significantly coupled to pfc theta phase, but not vice versa; (2) similarly, dg high-gamma amplitude was significantly coupled to ca1 theta phase, but not vice versa, and (3) the dg high-gamma-ca1 theta pac was significantly correlated with dg → ca1 granger causality, a well-established analytical measure of directional neural transmission. |
2020-10-16 |
2023-08-13 |
Not clear |
| Akira Nakayama, Manami Yoshida, Nao Kagawa, Tetsuji Naga. The neonicotinoids acetamiprid and imidacloprid impair neurogenesis and alter the microglial profile in the hippocampal dentate gyrus of mouse neonates. Journal of applied toxicology : JAT. vol 39. issue 6. 2020-10-15. PMID:30693975. |
few studies have assessed the activation of vertebrate nachrs and the neurodevelopmental toxicity following in utero or neonatal exposure to neonicotinoids; therefore, we evaluated the effects of ace or imi exposure on neurogenesis and microglial profiles in the developing hippocampal dentate gyrus (dg) of mouse neonates. |
2020-10-15 |
2023-08-13 |
mouse |
| Akira Nakayama, Manami Yoshida, Nao Kagawa, Tetsuji Naga. The neonicotinoids acetamiprid and imidacloprid impair neurogenesis and alter the microglial profile in the hippocampal dentate gyrus of mouse neonates. Journal of applied toxicology : JAT. vol 39. issue 6. 2020-10-15. PMID:30693975. |
on p27, brains were removed, and neurogenesis and microglial activation in the hippocampal dg were examined via immunohistochemistry. |
2020-10-15 |
2023-08-13 |
mouse |
| Akira Nakayama, Manami Yoshida, Nao Kagawa, Tetsuji Naga. The neonicotinoids acetamiprid and imidacloprid impair neurogenesis and alter the microglial profile in the hippocampal dentate gyrus of mouse neonates. Journal of applied toxicology : JAT. vol 39. issue 6. 2020-10-15. PMID:30693975. |
a reduction in neurogenesis in the hippocampal dg of neonates following ace, imi and nicotine treatment was found. |
2020-10-15 |
2023-08-13 |
mouse |
| Akira Nakayama, Manami Yoshida, Nao Kagawa, Tetsuji Naga. The neonicotinoids acetamiprid and imidacloprid impair neurogenesis and alter the microglial profile in the hippocampal dentate gyrus of mouse neonates. Journal of applied toxicology : JAT. vol 39. issue 6. 2020-10-15. PMID:30693975. |
these results suggest that exposure to ace and imi impairs neurogenesis and alters microglial profiles in the developing hippocampal dg following oral dosing in an early postnatal period. |
2020-10-15 |
2023-08-13 |
mouse |
| Maria Grazia Piancino, Alessandro Tortarolo, Antonella Polimeni, Ennio Bramanti, Placido Bramant. Altered mastication adversely impacts morpho-functional features of the hippocampus: A systematic review on animal studies in three different experimental conditions involving the masticatory function. PloS one. vol 15. issue 8. 2020-10-15. PMID:32817680. |
the literature reviewed agrees that a disturbed mastication is significantly associated with a reduced number of hippocampal pyramidal neurons in cornu ammonis (ca)1 and ca3, downregulation of brain derived neurotrophic factor (bdnf), reduced synaptic activity, reduced neurogenesis in the dentate gyrus (dg), glial proliferation, and reduced performances in behavioural tests, indicating memory impairment and reduced spatial orientation. |
2020-10-15 |
2023-08-13 |
Not clear |
| Jing Zhao, Chanel J Taylor, Estella A Newcombe, Mark D Spanevello, Imogen O'Keeffe, Leanne T Cooper, Dhanisha J Jhaveri, Andrew W Boyd, Perry F Bartlet. EphA4 Regulates Hippocampal Neural Precursor Proliferation in the Adult Mouse Brain by d-Serine Modulation of N-Methyl-d-Aspartate Receptor Signaling. Cerebral cortex (New York, N.Y. : 1991). vol 29. issue 10. 2020-10-13. PMID:30590507. |
the hippocampal dentate gyrus (dg) is a major region of the adult rodent brain in which neurogenesis occurs throughout life. |
2020-10-13 |
2023-08-13 |
mouse |
| Jing Zhao, Chanel J Taylor, Estella A Newcombe, Mark D Spanevello, Imogen O'Keeffe, Leanne T Cooper, Dhanisha J Jhaveri, Andrew W Boyd, Perry F Bartlet. EphA4 Regulates Hippocampal Neural Precursor Proliferation in the Adult Mouse Brain by d-Serine Modulation of N-Methyl-d-Aspartate Receptor Signaling. Cerebral cortex (New York, N.Y. : 1991). vol 29. issue 10. 2020-10-13. PMID:30590507. |
the epha4 receptor, which regulates neurogenesis and boundary formation in the developing brain, is also expressed in the adult dg, but whether it regulates adult hippocampal neurogenesis is not known. |
2020-10-13 |
2023-08-13 |
mouse |
| Jing Zhao, Chanel J Taylor, Estella A Newcombe, Mark D Spanevello, Imogen O'Keeffe, Leanne T Cooper, Dhanisha J Jhaveri, Andrew W Boyd, Perry F Bartlet. EphA4 Regulates Hippocampal Neural Precursor Proliferation in the Adult Mouse Brain by d-Serine Modulation of N-Methyl-d-Aspartate Receptor Signaling. Cerebral cortex (New York, N.Y. : 1991). vol 29. issue 10. 2020-10-13. PMID:30590507. |
epha4 was expressed by mature hippocampal dg neurons but not neural precursor cells, and an epha4 antagonist, epha4-fc, did not activate clonal cultures of precursors until they were co-cultured with non-precursor cells, indicating an indirect effect of epha4 on the regulation of precursor activity. |
2020-10-13 |
2023-08-13 |
mouse |
| Rita Soares, Filipa F Ribeiro, Diogo M Lourenço, Rui S Rodrigues, João B Moreira, Ana M Sebastião, Vanessa A Morais, Sara Xapell. Isolation and Expansion of Neurospheres from Postnatal (P1-3) Mouse Neurogenic Niches. Journal of visualized experiments : JoVE. issue 159. 2020-10-07. PMID:32510488. |
in the postnatal and adult brain, nspcs are mainly present in two neurogenic niches: the subventricular zone (svz) lining the lateral ventricles and the subgranular zone of the hippocampal dentate gyrus (dg). |
2020-10-07 |
2023-08-13 |
mouse |
| Sherif A Kamar, Hany W Abdel Malak, Shereen Adel Saa. Effect of caffeinated energy drinks on the structure of hippocampal cornu ammonis 1 and dentate gyrus of adult male albino rats. Anatomy & cell biology. vol 53. issue 3. 2020-10-07. PMID:32993281. |
however, the link between the impact of energy drinks on the structure of hippocampal cornu ammonis 1 (ca1) and dentate gyrus (dg), a highly vulnerable brain regions to various insults, has not yet documented. |
2020-10-07 |
2023-08-13 |
rat |
| Tingting Zhang, Juan Hong, Tingting Di, Ling Che. MPTP Impairs Dopamine D1 Receptor-Mediated Survival of Newborn Neurons in Ventral Hippocampus to Cause Depressive-Like Behaviors in Adult Mice. Frontiers in molecular neuroscience. vol 9. 2020-10-01. PMID:27790091. |
five consecutive days of 1-methyl-4-phenyl-1,2,3,6-tetrahydropyridine (mptp) injection in mice (mptp-mice) reduced dopaminergic fibers in hippocampal dentate gyrus (dg). |
2020-10-01 |
2023-08-13 |
mouse |
| Noemí Pallas-Bazarra, Asta Kastanauskaite, Jesús Avila, Javier DeFelipe, María Llorens-Martí. GSK-3β Overexpression Alters the Dendritic Spines of Developmentally Generated Granule Neurons in the Mouse Hippocampal Dentate Gyrus. Frontiers in neuroanatomy. vol 11. 2020-10-01. PMID:28344548. |
moreover, a unique feature of the dg is the occurrence of adult hippocampal neurogenesis, a process that gives rise to newborn granule neurons throughout life. |
2020-10-01 |
2023-08-13 |
mouse |