| Publication |
Sentence |
Publish Date |
Extraction Date |
Species |
| Thomas Frodl, Katharina Strehl, Angela Carballedo, Leonardo Tozzi, Myles Doyle, Francesco Amico, John Gormley, Grace Lavelle, Veronica O'Kean. Aerobic exercise increases hippocampal subfield volumes in younger adults and prevents volume decline in the elderly. Brain imaging and behavior. vol 14. issue 5. 2021-04-27. PMID:30927200. |
exercise improves both physical and mental health and increases neurogenesis in the dendate gyrus (dg) of the hippocampus. |
2021-04-27 |
2023-08-13 |
human |
| Thomas Frodl, Katharina Strehl, Angela Carballedo, Leonardo Tozzi, Myles Doyle, Francesco Amico, John Gormley, Grace Lavelle, Veronica O'Kean. Aerobic exercise increases hippocampal subfield volumes in younger adults and prevents volume decline in the elderly. Brain imaging and behavior. vol 14. issue 5. 2021-04-27. PMID:30927200. |
the aim of this study was to examine whether exercising, as compared to no change in regular physical activity, would impact on hippocampal volume, and in particular the core hippocampal structures, dg and cornu ammonis (ca) subfields, and whether any changes would be moderated by age. |
2021-04-27 |
2023-08-13 |
human |
| Jinxuan Cheng, Federico Scala, Francisco A Blanco, Sanyong Niu, Karen Firozi, Laura Keehan, Shalaka Mulherkar, Emmanouil Froudarakis, Lingyong Li, Joseph G Duman, Xiaolong Jiang, Kimberley F Tolia. The Rac-GEF Tiam1 Promotes Dendrite and Synapse Stabilization of Dentate Granule Cells and Restricts Hippocampal-Dependent Memory Functions. The Journal of neuroscience : the official journal of the Society for Neuroscience. vol 41. issue 6. 2021-04-27. PMID:33328293. |
the dentate gyrus (dg) controls information flow into the hippocampus and is critical for learning, memory, pattern separation, and spatial coding, while dg dysfunction is associated with neuropsychiatric disorders. |
2021-04-27 |
2023-08-13 |
Not clear |
| Jinxuan Cheng, Federico Scala, Francisco A Blanco, Sanyong Niu, Karen Firozi, Laura Keehan, Shalaka Mulherkar, Emmanouil Froudarakis, Lingyong Li, Joseph G Duman, Xiaolong Jiang, Kimberley F Tolia. The Rac-GEF Tiam1 Promotes Dendrite and Synapse Stabilization of Dentate Granule Cells and Restricts Hippocampal-Dependent Memory Functions. The Journal of neuroscience : the official journal of the Society for Neuroscience. vol 41. issue 6. 2021-04-27. PMID:33328293. |
in the hippocampus, tiam1 is predominantly expressed in the dg throughout life. |
2021-04-27 |
2023-08-13 |
Not clear |
| Dong Sun, Leena Milibari, Jin-Xiu Pan, Xiao Ren, Ling-Ling Yao, Yang Zhao, Chen Shen, Wen-Bing Chen, Fu-Lei Tang, Daehoon Lee, Jun-Shi Zhang, Lin Mei, Wen-Cheng Xion. Critical Roles of Embryonic Born Dorsal Dentate Granule Neurons for Activity-Dependent Increases in BDNF, Adult Hippocampal Neurogenesis, and Antianxiety-like Behaviors. Biological psychiatry. vol 89. issue 6. 2021-04-23. PMID:33183762. |
dentate gyrus (dg), a "gate" that controls information flow into the hippocampus, plays important roles in regulating both cognitive (e.g., spatial learning and memory) and mood behaviors. |
2021-04-23 |
2023-08-13 |
Not clear |
| Rocío Guerrero-Bautista, Aurelio Franco-García, Juana M Hidalgo, Francisco José Fernández-Gómez, Bruno Ribeiro Do Couto, M Victoria Milanés, Cristina Núñe. Distinct Regulation of Dopamine D3 Receptor in the Basolateral Amygdala and Dentate Gyrus during the Reinstatement of Cocaine CPP Induced by Drug Priming and Social Stress. International journal of molecular sciences. vol 22. issue 6. 2021-04-21. PMID:33803578. |
cocaine relapse engages the activity of memory-related nuclei, such as the basolateral amygdala (bla) and the hippocampal dentate gyrus (dg), which are responsible for emotional and episodic memories. |
2021-04-21 |
2023-08-13 |
Not clear |
| Dan-Ying Wang, An-Feng Luo, Qing-Ran Bai, Xiao-Li Gong, Yan Zheng, Qin Shen, Xiao-Ling Hu, Xiao-Min Wan. VCAM1 Labels a Subpopulation of Neural Stem Cells in the Adult Hippocampus and Contributes to Spatial Memory. Stem cell reports. vol 14. issue 6. 2021-04-19. PMID:32521248. |
active neural stem cells (anscs) and quiescent neural stem cells (qnscs) are two distinct subpopulations found in the adult hippocampal dentate gyrus (dg). |
2021-04-19 |
2023-08-13 |
mouse |
| Wei Ge, Chao Ren, Lei Xing, Lina Guan, Caiyi Zhang, Xuwen Sun, Guoping Wang, Haichen Niu, Sen Qu. Ginkgo biloba extract improves cognitive function and increases neurogenesis by reducing Aβ pathology in 5×FAD mice. American journal of translational research. vol 13. issue 3. 2021-04-13. PMID:33841671. |
after consecutive 4-month injections, mice were tested in learning memory tasks, aβ, and neurogenesis in the dentate gyrus (dg) of hippocampus and morphological characteristics of neurons in dg of hippocampus. |
2021-04-13 |
2023-08-13 |
mouse |
| Dongseok Park, Seungjoon Kim, Hyeonho Kim, Jungsu Shin, Hyeji Jung, Ji Won U. Seizure progression triggered by IQSEC3 loss is mitigated by reducing activated microglia in mice. Glia. vol 68. issue 12. 2021-04-06. PMID:32645240. |
in the current study, we show that mice with hippocampal dentate gyrus (dg)-specific iqsec3 knockdown (kd) exhibit microglial activation and death of dg granule cell. |
2021-04-06 |
2023-08-13 |
mouse |
| Ning-Ning Cai, Zheng-Zhu Wang, Xian-Chun Zhu, Yu Jiang, Wen-Qian Zhu, Rui Yang, Xue-Ming Zhan. Schisandrin A and B enhance the dentate gyrus neurogenesis in mouse hippocampus. Journal of chemical neuroanatomy. vol 105. 2021-04-02. PMID:32027950. |
since the neurogenesis in the hippocampal dentate gyrus (dg) is more important to learning, memory and cognition, here we further examined their effects on the adult dg neurogenesis. |
2021-04-02 |
2023-08-13 |
mouse |
| Branden R Nelson, Rebecca D Hodge, Ray Am Daza, Prem Prakash Tripathi, Sebastian J Arnold, Kathleen J Millen, Robert F Hevne. Intermediate progenitors support migration of neural stem cells into dentate gyrus outer neurogenic niches. eLife. vol 9. 2021-03-30. PMID:32238264. |
the hippocampal dentate gyrus (dg) is a unique brain region maintaining neural stem cells (ncss) and neurogenesis into adulthood. |
2021-03-30 |
2023-08-13 |
mouse |
| Aline Siteneski, Gislaine Olescowicz, Francis L Pazini, Anderson Camargo, Daiane B Fraga, Patricia S Brocardo, Joana Gil-Mohapel, Mauricio P Cunha, Ana Lúcia S Rodrigue. Antidepressant-like and pro-neurogenic effects of physical exercise: the putative role of FNDC5/irisin pathway. Journal of neural transmission (Vienna, Austria : 1996). vol 127. issue 3. 2021-03-26. PMID:31974720. |
immunohistochemical analyses to evaluate hippocampal cell proliferation, neuronal survival, and neuronal commitment and maturation, as well as expression of fndc5 c-terminal fragment were performed in the entire, dorsal, and ventral dentate gyrus (dg) of the hippocampus. |
2021-03-26 |
2023-08-13 |
mouse |
| Aline Siteneski, Gislaine Olescowicz, Francis L Pazini, Anderson Camargo, Daiane B Fraga, Patricia S Brocardo, Joana Gil-Mohapel, Mauricio P Cunha, Ana Lúcia S Rodrigue. Antidepressant-like and pro-neurogenic effects of physical exercise: the putative role of FNDC5/irisin pathway. Journal of neural transmission (Vienna, Austria : 1996). vol 127. issue 3. 2021-03-26. PMID:31974720. |
this antidepressant-like effect was accompanied by an increase in hippocampal cell proliferation, hippocampal neuronal differentiation, and neuronal survival in the dorsal and ventral dg. |
2021-03-26 |
2023-08-13 |
mouse |
| Aline Siteneski, Gislaine Olescowicz, Francis L Pazini, Anderson Camargo, Daiane B Fraga, Patricia S Brocardo, Joana Gil-Mohapel, Mauricio P Cunha, Ana Lúcia S Rodrigue. Antidepressant-like and pro-neurogenic effects of physical exercise: the putative role of FNDC5/irisin pathway. Journal of neural transmission (Vienna, Austria : 1996). vol 127. issue 3. 2021-03-26. PMID:31974720. |
finally, physical exercise also resulted in increased number of fndc5-positive cells in the hippocampal dg as well as elevated fndc5 c-terminal and fndc5/irisin immunocontent in the entire hippocampus. |
2021-03-26 |
2023-08-13 |
mouse |
| Xiaomin Zhang, Peter Jona. Integration of spatial and non-spatial information by heterogeneous dentate gyrus granule cells. Journal of life sciences (Westlake Village, Calif.). vol 2. issue 4. 2021-03-26. PMID:33409506. |
thus, the dg sits in a strategic position to gate the flow of information from the neocortex into the hippocampal network. |
2021-03-26 |
2023-08-13 |
Not clear |
| A González-Maciel, R M Romero-Velázquez, A Alfaro-Rodríguez, P Sanchez Aparicio, R Reynoso-Roble. Prenatal exposure to oxcarbazepine increases hippocampal apoptosis in rat offspring. Journal of chemical neuroanatomy. vol 103. 2021-03-23. PMID:31794794. |
apoptosis was detected at three postnatal ages using the tunel technique in the ca1, and ca3 regions of the hippocampus and in the dentate gyrus (dg); neurogenesis was assessed in the dg using an antibody against doublecortin. |
2021-03-23 |
2023-08-13 |
rat |
| Jiawen Huang, Chongkun Shen, Ran Ye, Yafei Shi, Weirong L. The Effect of Early Maternal Separation Combined With Adolescent Chronic Unpredictable Mild Stress on Behavior and Synaptic Plasticity in Adult Female Rats. Frontiers in psychiatry. vol 12. 2021-03-23. PMID:33746787. |
also, few nissl bodies in the hippocampus ca1 and dg regions, less percentage of syn-positive cells, and downregulated expressions of syn, psd-95, and gap43 were found in the hippocampus of rats in ms+cums group. |
2021-03-23 |
2023-08-13 |
rat |
| Zane R Lybrand, Sonal Goswami, Jingfei Zhu, Veronica Jarzabek, Nikolas Merlock, Mahafuza Aktar, Courtney Smith, Ling Zhang, Parul Varma, Kyung-Ok Cho, Shaoyu Ge, Jenny Hsie. A critical period of neuronal activity results in aberrant neurogenesis rewiring hippocampal circuitry in a mouse model of epilepsy. Nature communications. vol 12. issue 1. 2021-03-18. PMID:33658509. |
in the mammalian hippocampus, adult-born granule cells (abgcs) contribute to the function of the dentate gyrus (dg). |
2021-03-18 |
2023-08-13 |
mouse |
| Jasper O Nuninga, René C W Mandl, Marco P Boks, Steven Bakker, Metten Somers, Sophie M Heringa, Wendy Nieuwdorp, Hans Hoogduin, René S Kahn, Peter Luijten, Iris E C Somme. Volume increase in the dentate gyrus after electroconvulsive therapy in depressed patients as measured with 7T. Molecular psychiatry. vol 25. issue 7. 2021-03-17. PMID:30867562. |
in the animal analog of ect, neurogenesis in the dentate gyrus (dg) of the hippocampus is observed. |
2021-03-17 |
2023-08-13 |
human |
| Jasper O Nuninga, René C W Mandl, Marco P Boks, Steven Bakker, Metten Somers, Sophie M Heringa, Wendy Nieuwdorp, Hans Hoogduin, René S Kahn, Peter Luijten, Iris E C Somme. Volume increase in the dentate gyrus after electroconvulsive therapy in depressed patients as measured with 7T. Molecular psychiatry. vol 25. issue 7. 2021-03-17. PMID:30867562. |
if the volume increase of the hippocampus in humans is attributable to neurogenesis, it is expected to be exclusively present in the dg, whereas other processes (angiogenesis, synaptogenesis) also affect other subfields. |
2021-03-17 |
2023-08-13 |
human |