| Publication |
Sentence |
Publish Date |
Extraction Date |
Species |
| S S Sorokina, A E Malkov, L V Shubina, S I Zaichkina, V A Pikalo. Low dose of carbon ion irradiation induces early delayed cognitive impairments in mice. Radiation and environmental biophysics. vol 60. issue 1. 2021-06-22. PMID:33392787. |
nissl staining revealed a reduction in the number of cells in the dorsal hippocampus of irradiated mice, with the most pronounced reduction in cell density observed in the dentate gyrus (dg) hilus. |
2021-06-22 |
2023-08-13 |
mouse |
| Kimia RayatSanati, Shole Jamali, Amir Arash Hassanlou, Abbas Haghparas. Blockade of orexin receptors in the hippocampal dentate gyrus reduced the extinction latency of morphine-induced place preference in male rats. Neuroscience letters. vol 756. 2021-06-22. PMID:33974952. |
the dentate gyrus (dg) of the hippocampus receives orexinergic projections from the lateral hypothalamus that has been approved as a critical area arbitrating the maintenance of drug-seeking behavior following the extinction. |
2021-06-22 |
2023-08-13 |
rat |
| Hui Li, Jie Gao, Yue Chang, Kexin Li, Lei Wang, Chuanxia Ju, Fang Zhan. JWX-A0108, a positive allosteric modulator of α7 nAChR, attenuates cognitive deficits in APP/PS1 mice by suppressing NF-κB-mediated inflammation. International immunopharmacology. vol 96. 2021-06-22. PMID:33975230. |
nissl staining showed that the ca3 and dg regions of hippocampus were damaged in app/ps1 mice, which was improved by jwx-a0108. |
2021-06-22 |
2023-08-13 |
mouse |
| Sinead Rooney, Anupam Sah, Michael S Unger, Maria Kharitonova, Simone B Sartori, Christoph Schwarzer, Ludwig Aigner, Helmut Kettenmann, Susanne A Wolf, Nicolas Singewal. Neuroinflammatory alterations in trait anxiety: modulatory effects of minocycline. Translational psychiatry. vol 10. issue 1. 2021-06-18. PMID:32732969. |
in particular, the dentate gyrus (dg) of the hippocampus of habs exhibited enhanced density and average cell area of iba1+, and density of phagocytic (cd68+/iba1+) microglia compared to normal anxiety (nab) controls. |
2021-06-18 |
2023-08-13 |
mouse |
| Farah Chamaa, Batoul Darwish, Ziad Nahas, Elie D Al-Chaer, Nayef E Saadé, Wassim Abou-Khei. Long-term stimulation of the anteromedial thalamus increases hippocampal neurogenesis and spatial reference memory in adult rats. Behavioural brain research. vol 402. 2021-06-18. PMID:33417991. |
previous work from our group showed that a single session of dbs to the anteromedial thalamic nucleus (amn) in awake rats, increased proliferation of stem/progenitor cells in the dentate gyrus (dg) of the hippocampus. |
2021-06-18 |
2023-08-13 |
rat |
| Miguel A Núñez-Ochoa, Gustavo A Chiprés-Tinajero, Laura Medina-Cej. Evaluation of the hippocampal immunoreactivity of the serotonin 5-HT1A, 5-HT2 and 5-HT7 receptors in a pilocarpine temporal lobe epilepsy rat model with fast ripples. Neuroreport. vol 32. issue 4. 2021-06-18. PMID:33470771. |
a general depletion of the 5-ht and 5-hiia levels in hippocampal tissue from epileptic animals compared with those in controls was observed; in addition, a general decrease in immunoreactivity for the three receptors was found, especially in the dg, which may support the establishment of an excitatory/inhibitory imbalance in the trisynaptic circuit that underlies the fr generation process. |
2021-06-18 |
2023-08-13 |
rat |
| Leonardo Aguilar-Hernández, Andrea Judith Vázquez-Hernández, Diana Frida de-Lima-Mar, Rubén Antonio Vázquez-Roque, Hiram Tendilla-Beltrán, Gonzalo Flore. Memory and dendritic spines loss, and dynamic dendritic spines changes are age-dependent in the rat. Journal of chemical neuroanatomy. vol 110. 2021-06-16. PMID:32950615. |
in the present study, in male rats aged 3, 6, and 18 months, we analyzed the locomotor activity and also short and long-term memory using the novel object recognition test (nort), in addition to evaluating the dendritic length and the number of dendritic spines in the prefrontal cortex (pfc) and in the ca1, ca3 and dg regions of the dorsal hippocampus using golgi-cox staining. |
2021-06-16 |
2023-08-13 |
rat |
| Alexander V Maltsev, Natalia V Bal, Pavel M Balaba. Serine/Threonine Phosphatases in LTP: Two B or Not to Be the Protein Synthesis Blocker-Induced Impairment of Early Phase. International journal of molecular sciences. vol 22. issue 9. 2021-06-15. PMID:34064311. |
direct measurement of the no production in hippocampal slices by the no-specific fluorescent probe daf-fm revealed that psbs strongly stimulate the no concentration in all studied brain areas: ca1, ca3, and dentate gyrus (dg). |
2021-06-15 |
2023-08-13 |
Not clear |
| Lucas B Comeras, Noa Hörmer, Pradeepa Mohan Bethuraj, Ramon O Tasa. NPY Released From GABA Neurons of the Dentate Gyrus Specially Reduces Contextual Fear Without Affecting Cued or Trace Fear. Frontiers in synaptic neuroscience. vol 13. 2021-06-15. PMID:34122036. |
importantly, npy in the dorsal dg was not only expressed in somatostatin neurons, but also in parvalbumin-positive basket cells and axoaxonic cells, indicating intense feedback and feedforward modulation of hippocampal signaling and precise curtailing of neuronal engrams. |
2021-06-15 |
2023-08-13 |
Not clear |
| Lucas B Comeras, Noa Hörmer, Pradeepa Mohan Bethuraj, Ramon O Tasa. NPY Released From GABA Neurons of the Dentate Gyrus Specially Reduces Contextual Fear Without Affecting Cued or Trace Fear. Frontiers in synaptic neuroscience. vol 13. 2021-06-15. PMID:34122036. |
thus, these findings suggest that co-release of npy from specific interneuron populations of the dorsal dg modifies dedicated aspects of hippocampal processing by sharpening the activation of neural engrams and the consecutive fear response. |
2021-06-15 |
2023-08-13 |
Not clear |
| Gislaine Olescowicz, Tuane B Sampaio, Cristine de Paula Nascimento-Castro, Patricia S Brocardo, Joana Gil-Mohapel, Ana Lúcia S Rodrigue. Protective Effects of Agmatine Against Corticosterone-Induced Impairment on Hippocampal mTOR Signaling and Cell Death. Neurotoxicity research. vol 38. issue 2. 2021-06-14. PMID:32399718. |
treatment on the levels of phosphorylated mtor (p-mtor), neuronal death, and overall volume in the hippocampal dentate gyrus (dg) of mice exposed to chronic corticosterone (20 mg/kg, p.o.) |
2021-06-14 |
2023-08-13 |
mouse |
| Gislaine Olescowicz, Tuane B Sampaio, Cristine de Paula Nascimento-Castro, Patricia S Brocardo, Joana Gil-Mohapel, Ana Lúcia S Rodrigue. Protective Effects of Agmatine Against Corticosterone-Induced Impairment on Hippocampal mTOR Signaling and Cell Death. Neurotoxicity research. vol 38. issue 2. 2021-06-14. PMID:32399718. |
agmatine, similarly to fluoxetine, was capable of reversing this alteration in the entire dg, an effect more evident in the ventral portion of the hippocampus. |
2021-06-14 |
2023-08-13 |
mouse |
| Justin J Botterill, K Yaragudri Vinod, Kathleen J Gerencer, Cátia M Teixeira, John J LaFrancois, Helen E Scharfma. Bidirectional Regulation of Cognitive and Anxiety-like Behaviors by Dentate Gyrus Mossy Cells in Male and Female Mice. The Journal of neuroscience : the official journal of the Society for Neuroscience. vol 41. issue 11. 2021-06-11. PMID:33472828. |
the dentate gyrus (dg) of the hippocampus is important for cognition and behavior. |
2021-06-11 |
2023-08-13 |
mouse |
| Kyle R Jensen, Coralie Berthoux, Kaoutsar Nasrallah, Pablo E Castill. Multiple cannabinoid signaling cascades powerfully suppress recurrent excitation in the hippocampus. Proceedings of the National Academy of Sciences of the United States of America. vol 118. issue 4. 2021-06-09. PMID:33468648. |
by targeting the ipsi- and contralateral dentate gyrus (dg) along the dorsoventral axis of the hippocampus, mcs form an extensive recurrent excitatory circuit (gc-mc-gc) whose dysregulation can promote epilepsy. |
2021-06-09 |
2023-08-13 |
Not clear |
| Max Rudolph, Christian W Schmeer, Madlen Günther, Florus Woitke, Carolin Kathner-Schaffert, Lina Karapetow, Julia Lindner, Thomas Lehmann, Gustav Jirikowski, Otto W Witte, Christoph Redecker, Silke Keine. Microglia-mediated phagocytosis of apoptotic nuclei is impaired in the adult murine hippocampus after stroke. Glia. vol 69. issue 8. 2021-06-09. PMID:33942391. |
here, we evaluated the effect of a prefrontal stroke lesion on the phagocytic activity of microglia in the dentate gyrus (dg) of the hippocampus. |
2021-06-09 |
2023-08-13 |
mouse |
| Dan Wu, Xiaomeng Xu, Na Sun, Dongmei Li, Beiwei Zhu, Songyi Li. AGLPM and QMDDQ peptides exert a synergistic action on memory improvement against scopolamine-induced amnesiac mice. Food & function. vol 11. issue 12. 2021-06-07. PMID:33242042. |
furthermore, combination treatment with qmddq and aglpm could significantly reduce the acetylcholinesterase (ache) level and increase the acetylcholine (ach) level in the hippocampus, and noticeably improve the pathological morphology of the neuron cells in hippocampal regions ca1 and ca2 and dentate gyrus (dg). |
2021-06-07 |
2023-08-13 |
mouse |
| Luofang Peng, Maoen Zhu, Yong Yang, Feng Lu, Xian Liu, Qulian Guo, Tao Zhon. Repeated Neonatal Isoflurane Exposure is Associated with Higher Susceptibility to Chronic Variable Stress-induced Behavioural and Neuro-inflammatory Alterations. Neuroscience. vol 465. 2021-06-04. PMID:33951503. |
in mice experiencing serial neonatal isoflurane exposure, we detected a significant enhancement in anxiety levels following cvs procedures, together with enhanced neuronal activity, and exacerbated neuroinflammation in the basolateral amygdaloid nuclei (bla) and hippocampal dentate gyrus (dg) regions. |
2021-06-04 |
2023-08-13 |
mouse |
| Minlan Yuan, Hongru Zhu, Yuchen Li, Fenfen Ge, Su Lui, Qiyong Gong, Changjian Qiu, Huan Song, Wei Zhan. The DRD2 Taq1A polymorphism moderates the effect of PTSD symptom severity on the left hippocampal CA3 volume: a pilot study. Psychopharmacology. 2021-06-04. PMID:34086098. |
the hippocampus, especially the ca1, ca3, and dentate gyrus (dg) subfields, is reported to be associated with post-traumatic stress disorder (ptsd) after trauma. |
2021-06-04 |
2023-08-13 |
Not clear |
| Minlan Yuan, Hongru Zhu, Yuchen Li, Fenfen Ge, Su Lui, Qiyong Gong, Changjian Qiu, Huan Song, Wei Zhan. The DRD2 Taq1A polymorphism moderates the effect of PTSD symptom severity on the left hippocampal CA3 volume: a pilot study. Psychopharmacology. 2021-06-04. PMID:34086098. |
the aim of this study is to examine whether the dopamine d2 receptor (drd2) taq1a polymorphism, which is associated with both hippocampal function and ptsd, moderated the association between ptsd severity and hippocampal ca1, ca3 and dg volumes. |
2021-06-04 |
2023-08-13 |
Not clear |
| Xinjian Zhu, Yuanyuan Yao, Jiurong Yang, Qiyue Ge, Diejing Niu, Xiufang Liu, Chenchen Zhang, Guangming Gan, Aifeng Zhang, Honghong Ya. Seizure-induced neuroinflammation contributes to ectopic neurogenesis and aggressive behavior in pilocarpine-induced status epilepticus mice. Neuropharmacology. vol 170. 2021-06-03. PMID:32179291. |
neurogenesis persists throughout life in the hippocampal dentate gyrus (dg) to maintain proper brain function. |
2021-06-03 |
2023-08-13 |
mouse |