Publication |
Sentence |
Publish Date |
Extraction Date |
Species |
Emanuele Mocciaro, Auston Grant, Rinat O Esenaliev, Irene Y Petrov, Yuriy Petrov, Stacy L Sell, Nicole L Hausser, Jutatip Guptarak, Elizabeth Bishop, Margaret A Parsley, Ian J Bolding, Kathia M Johnson, Maxwell Lidstone, Donald S Prough, Maria-Adelaide Micc. Non-Invasive Transcranial Nano-Pulsed Laser Therapy Ameliorates Cognitive Function and Prevents Aberrant Migration of Neural Progenitor Cells in the Hippocampus of Rats Subjected to Traumatic Brain Injury. Journal of neurotrauma. vol 37. issue 8. 2021-08-18. PMID:31856661. |
the hippocampus, one of the most affected brain region after tbi, plays a critical role in learning and memory and is one of the only two regions in the brain in which new neurons are generated throughout life from neural stem cells (nsc) in the dentate gyrus (dg). |
2021-08-18 |
2023-08-13 |
rat |
Zahra Shabani, Mohsen Jafarzadeh Gharehziaaddi. Effects and Potential Mechanisms of Alcohol Use Disorder on the Fate Determination of Newly Born Neurons in the Hippocampus. Alcohol and alcoholism (Oxford, Oxfordshire). vol 55. issue 6. 2021-08-18. PMID:32814954. |
the subventricular zone (svz), lining the lateral ventricle, and the subgranular zone (sgz) in the dentate gyrus (dg) of the hippocampus are the two major neurogenic regions in the adult brain. |
2021-08-18 |
2023-08-13 |
Not clear |
Shao-Han Chang, Ying Hao Yu, Alan He, Chen Yin Ou, Bai Chuang Shyu, Andrew Chih Wei Huan. BDNF Protein and BDNF mRNA Expression of the Medial Prefrontal Cortex, Amygdala, and Hippocampus during Situational Reminder in the PTSD Animal Model. Behavioural neurology. vol 2021. 2021-08-18. PMID:33763156. |
whether bdnf protein and bdnf mrna expression of the medial prefrontal cortex (mpfc; cingulated cortex area 1 (cg1), prelimbic cortex (prl), and infralimbic cortex (il)), amygdala, and hippocampus (ca1, ca2, ca3, and dentate gyrus (dg)) was involved in fear of posttraumatic stress disorder (ptsd) during the situational reminder of traumatic memory remains uncertain. |
2021-08-18 |
2023-08-13 |
rat |
Ying-Chou Wang, Wei-Che Chiu, Cai-N Cheng, Chiang Lee, Andrew Chih Wei Huan. Examination of neuroinflammatory cytokine interleukin-1 beta expression in the medial prefrontal cortex, amygdala, and hippocampus for the paradoxical effects of reward and aversion induced by morphine. Neuroscience letters. vol 760. 2021-08-17. PMID:34153368. |
however, no research examined whether neuroinflammatory changes in the mpfc [including cingulate cortex area 1 (cg1); prelimbic cortex (prl); infralimbic cortex (il)], basolateral amygdala, and hippocampus [e.g., ca1, ca2, ca3, and dentate gyrus (dg)] after morphine-induced reward in conditioned place preference (cpp) and aversion in conditioned taste aversion (cta). |
2021-08-17 |
2023-08-13 |
Not clear |
Ying-Chou Wang, Wei-Che Chiu, Cai-N Cheng, Chiang Lee, Andrew Chih Wei Huan. Examination of neuroinflammatory cytokine interleukin-1 beta expression in the medial prefrontal cortex, amygdala, and hippocampus for the paradoxical effects of reward and aversion induced by morphine. Neuroscience letters. vol 760. 2021-08-17. PMID:34153368. |
the prl and il of the mpfc, the bla of the amygdala, the ca1, ca2, ca3, and dg of the hippocampus but not the cg1 presented hyperactive il-1β expression in response to morphine's aversion and reward. |
2021-08-17 |
2023-08-13 |
Not clear |
Youngjae Ryu, Misato Iwashita, Wonyoung Lee, Kenji Uchimura, Yoichi Kosod. A Shift in Tissue Stiffness During Hippocampal Maturation Correlates to the Pattern of Neurogenesis and Composition of the Extracellular Matrix. Frontiers in aging neuroscience. vol 13. 2021-08-17. PMID:34393762. |
neurogenesis is observed in restricted niches, including the dentate gyrus (dg) of the hippocampus, throughout mammalian lifetimes. |
2021-08-17 |
2023-08-13 |
Not clear |
Miguel Flor-García, Jesús Ávila, María Llorens-Martí. GSK-3β S9A overexpression leads murine hippocampal neural precursors to acquire an astroglial phenotype in vivo. Developmental neurobiology. vol 81. issue 5. 2021-08-16. PMID:33955712. |
the addition of new neurons to the existing hippocampal circuitry persists in the adult dentate gyrus (dg). |
2021-08-16 |
2023-08-13 |
mouse |
Muhammad M Hossain, Abdelmadjid Belkadi, Sara Al-Haddad, Jason R Richardso. Deltamethrin Exposure Inhibits Adult Hippocampal Neurogenesis and Causes Deficits in Learning and Memory in Mice. Toxicological sciences : an official journal of the Society of Toxicology. vol 178. issue 2. 2021-08-13. PMID:32976580. |
recent studies demonstrate that adult born neurons in the dentate gyrus (dg) in the hippocampus can functionally integrate into the existing neuronal circuitry and contribute to hippocampal-dependent learning and memory. |
2021-08-13 |
2023-08-13 |
mouse |
Muhammad M Hossain, Abdelmadjid Belkadi, Sara Al-Haddad, Jason R Richardso. Deltamethrin Exposure Inhibits Adult Hippocampal Neurogenesis and Causes Deficits in Learning and Memory in Mice. Toxicological sciences : an official journal of the Society of Toxicology. vol 178. issue 2. 2021-08-13. PMID:32976580. |
deltamethrin exposure significantly decreased bromodeoxyuridine (brdu)-positive cells (39%) and ki67+ cells (47%) in the dg of the hippocampus, indicating decreased cellular proliferation. |
2021-08-13 |
2023-08-13 |
mouse |
I V Kastyro, I V Reshetov, G V Khamidulin, S S Shilin, V I Torshin, M G Kostyaeva, V I Popadyuk, T Y Yunusov, P E Shmaevsky, K P Shalamov, A D Kupryakova, E S Doroginskaya, A D Sedelnikov. Influence of Surgical Trauma in the Nasal Cavity on the Expression of p53 Protein in the Hippocampus of Rats. Doklady. Biochemistry and biophysics. vol 497. issue 1. 2021-08-13. PMID:33895923. |
a quantitative assessment of the apoptosis of neurons in the pyramidal layer of the hippocampus in the subfields ca1, ca2, ca3, and dentate gyrus (dg) on days 2, 4, and 6 after surgery was carried out. |
2021-08-13 |
2023-08-13 |
rat |
Hao Wu, Yong Liu, Lishuo Liu, Qiang Meng, Changwang Du, Kuo Li, Shan Dong, Yong Zhang, Huanfa Li, Hua Zhan. Decreased expression of the clock gene Bmal1 is involved in the pathogenesis of temporal lobe epilepsy. Molecular brain. vol 14. issue 1. 2021-08-12. PMID:34261484. |
knockout of bmal1 in hippocampal dentate gyrus (dg) neurons of bmal1 |
2021-08-12 |
2023-08-13 |
human |
Victor Rodrigues Santos, Igor Santana Melo, Amanda Larissa Dias Pacheco, Olagide Wagner de Castr. Life and death in the hippocampus: What's bad? Epilepsy & behavior : E&B. vol 121. issue Pt B. 2021-08-11. PMID:31759972. |
classically, neurodegeneration affects sensitive areas of the hippocampus, such as dentate gyrus (dg) hilus, as well as specific fields of the ammon's horn, ca3, and ca1. |
2021-08-11 |
2023-08-13 |
Not clear |
Priya Gami-Patel, Irene van Dijken, Lieke H Meeter, Shamiram Melhem, Tjado H J Morrema, Wiep Scheper, John C van Swieten, Annemieke J M Rozemuller, Anke A Dijkstra, Jeroen J M Hoozeman. Unfolded protein response activation in C9orf72 frontotemporal dementia is associated with dipeptide pathology and granulovacuolar degeneration in granule cells. Brain pathology (Zurich, Switzerland). vol 31. issue 1. 2021-08-11. PMID:32865835. |
in the hippocampus, overall levels of pperk and peif2α were higher in c9-ftd, including in granule cells of the dentate gyrus (dg). |
2021-08-11 |
2023-08-13 |
human |
Priya Gami-Patel, Irene van Dijken, Lieke H Meeter, Shamiram Melhem, Tjado H J Morrema, Wiep Scheper, John C van Swieten, Annemieke J M Rozemuller, Anke A Dijkstra, Jeroen J M Hoozeman. Unfolded protein response activation in C9orf72 frontotemporal dementia is associated with dipeptide pathology and granulovacuolar degeneration in granule cells. Brain pathology (Zurich, Switzerland). vol 31. issue 1. 2021-08-11. PMID:32865835. |
in addition, increased levels of ck1δ were observed in granule cells in the dg of the hippocampus and granular layer of the cerebellum in c9-ftd. |
2021-08-11 |
2023-08-13 |
human |
Elham Taha, Sudarshan Patil, Iliana Barrera, Julia Panov, Mohammad Khamaisy, Christopher G Proud, Clive R Bramham, Kobi Rosenblu. eEF2/eEF2K Pathway in the Mature Dentate Gyrus Determines Neurogenesis Level and Cognition. Current biology : CB. vol 30. issue 18. 2021-08-09. PMID:32707059. |
levels of adult neurogenesis in the dentate gyrus (dg) of the hippocampus are correlated with unique cognitive functions. |
2021-08-09 |
2023-08-13 |
mouse |
Ruxin Xie, Zhongke Wang, Tianyao Liu, Rui Xiao, Keyi Lv, Chuan Wu, Yi Luo, Yun Cai, Xiaotang Fa. AAV Delivery of shRNA Against TRPC6 in Mouse Hippocampus Impairs Cognitive Function. Frontiers in cell and developmental biology. vol 9. 2021-07-31. PMID:34327201. |
gene silencing of trpc6 was performed by injecting adeno-associated virus (aav) expressing trpc6-specific shrna (shrna-trpc6) into the hippocampal dentate gyrus (dg). |
2021-07-31 |
2023-08-13 |
mouse |
David Alcantara-Gonzalez, Elissavet Chartampila, Chiara Criscuolo, Helen E Scharfma. Early changes in synaptic and intrinsic properties of dentate gyrus granule cells in a mouse model of Alzheimer's disease neuropathology and atypical effects of the cholinergic antagonist atropine. Neurobiology of disease. vol 152. 2021-07-30. PMID:33484828. |
several studies have suggested that the hippocampal dentate gyrus (dg) may be an important area where hyperexcitability occurs. |
2021-07-30 |
2023-08-13 |
mouse |
Pim R A Heckman, Femke Roig Kuhn, Frank Raven, Youri G Bolsius, Jos Prickaerts, Peter Meerlo, Robbert Haveke. Phosphodiesterase inhibitors roflumilast and vardenafil prevent sleep deprivation-induced deficits in spatial pattern separation. Synapse (New York, N.Y.). vol 74. issue 6. 2021-07-29. PMID:32056276. |
in the present study, we assessed in mice whether sd also affects spatial pattern separation, a cognitive process that specifically requires the dentate gyrus (dg) subregion of the hippocampus. |
2021-07-29 |
2023-08-13 |
mouse |
Ye Li, Cuiqin Fan, Rui Gao, Tian Lan, Wenjing Wang, Shu Yan Y. Hippocampal miR-211-5p regulates neurogenesis and depression-like behaviors in the rat. Neuropharmacology. vol 194. 2021-07-28. PMID:34062164. |
in the present study, we screened mirna expression profiles and found that mir-211-5p was significantly down-regulated within the dentate gyrus (dg) hippocampus in the chronic unpredictable mild stress (cums) induced rat model of depression. |
2021-07-28 |
2023-08-13 |
rat |
Ye Li, Cuiqin Fan, Rui Gao, Tian Lan, Wenjing Wang, Shu Yan Y. Hippocampal miR-211-5p regulates neurogenesis and depression-like behaviors in the rat. Neuropharmacology. vol 194. 2021-07-28. PMID:34062164. |
taken together, the results of our study reveal that altered levels of mir-211-5p in the hippocampal dg area exert a significant impact on neurogenesis, apoptosis and thus depression-like behaviors in rats. |
2021-07-28 |
2023-08-13 |
rat |