| Publication |
Sentence |
Publish Date |
Extraction Date |
Species |
| Yasaman Razavi, Fariborz Keyhanfar, Abbas Haghparast, Ronak Shabani, Mehdi Mehdizade. Cannabidiol promotes neurogenesis in the dentate gyrus during an abstinence period in rats following chronic exposure to methamphetamine. Metabolic brain disease. vol 36. issue 6. 2021-09-09. PMID:34143376. |
to determine whether cannabidiol (cbd) can promote proliferation and maturation of neuronal progenitor cells, this study investigated the cbd effect on neurogenesis in the hippocampal dentate gyrus (dg) following chronic exposure to meth in rats. |
2021-09-09 |
2023-08-13 |
human |
| Saiedeh Arabmoazzen, Mohammad Ali Mirsheka. Evaluation of the effects of metformin as adenosine monophosphate-activated protein kinase activator on spatial learning and memory in a rat model of multiple sclerosis disease. Biomedicine & pharmacotherapy = Biomedecine & pharmacotherapie. vol 141. 2021-09-08. PMID:34323699. |
here, we have tried to study the preservative effects of met as adenosine monophosphate-activated protein kinase (ampk) activator on the hippocampus dentate gyrus (dg) neuronal firing pattern, motor coordination, and learning & memory loss following ms induction. |
2021-09-08 |
2023-08-13 |
rat |
| Saiedeh Arabmoazzen, Mohammad Ali Mirsheka. Evaluation of the effects of metformin as adenosine monophosphate-activated protein kinase activator on spatial learning and memory in a rat model of multiple sclerosis disease. Biomedicine & pharmacotherapy = Biomedecine & pharmacotherapie. vol 141. 2021-09-08. PMID:34323699. |
a neuronal single-unit recording was measured from hippocampus dg. |
2021-09-08 |
2023-08-13 |
rat |
| Pen-Sen Huang, Ping-Yen Tsai, Ling-Yu Yang, Daniela Lecca, Weiming Luo, Dong Seok Kim, Barry J Hoffer, Yung-Hsiao Chiang, Nigel H Greig, Jia-Yi Wan. 3,6'-Dithiopomalidomide Ameliorates Hippocampal Neurodegeneration, Microgliosis and Astrogliosis and Improves Cognitive Behaviors in Rats with a Moderate Traumatic Brain Injury. International journal of molecular sciences. vol 22. issue 15. 2021-09-08. PMID:34361041. |
the number of degenerating neurons in the ca1 and dentate gyrus (dg) regions of the hippocampus after a tbi was reduced by pom and dp. |
2021-09-08 |
2023-08-13 |
rat |
| Katarzyna Głombik, Jan Detka, Bartosz Bobula, Joanna Bąk, Magdalena Kusek, Krzysztof Tokarski, Bogusława Budziszewsk. Contribution of Hypothyroidism to Cognitive Impairment and Hippocampal Synaptic Plasticity Regulation in an Animal Model of Depression. International journal of molecular sciences. vol 22. issue 4. 2021-09-06. PMID:33562494. |
a weakening of memory processes in the wky rats is shown behaviorally, and in the reduction of long-term potentiation (ltp) in the dentate gyrus (dg) and ca1 hippocampal regions. |
2021-09-06 |
2023-08-13 |
rat |
| Rachel K Nauer, Matthew F Dunne, Chantal E Stern, Thomas W Storer, Karin Scho. Improving fitness increases dentate gyrus/CA3 volume in the hippocampal head and enhances memory in young adults. Hippocampus. vol 30. issue 5. 2021-09-02. PMID:31588607. |
the majority of human studies have focused on the potential for exercise to reduce brain atrophy and attenuate cognitive decline in older adults, whereas animal studies often center on exercise-induced neurogenesis and hippocampal plasticity in the dentate gyrus (dg) of young adult animals. |
2021-09-02 |
2023-08-13 |
human |
| Hweeling Lee, Rüdiger Stirnberg, Sichu Wu, Xin Wang, Tony Stöcker, Sonja Jung, Christian Montag, Nikolai Axmache. Genetic Alzheimer's Disease Risk Affects the Neural Mechanisms of Pattern Separation in Hippocampal Subfields. Current biology : CB. vol 30. issue 21. 2021-09-02. PMID:32916120. |
using ultra-high-field (7t) functional magnetic resonance imaging (fmri), apoe-ε3-ε3 carriers predominantly recruited cornu ammonis 3 (ca3) during a spatial mnemonic discrimination task, whereas apoe-ε3-ε4 and apoe-ε3-ε2 carriers engaged ca3 and dentate gyrus (dg) to the same degree. |
2021-09-02 |
2023-08-13 |
Not clear |
| Zhong-Xuan Ma, Ru-Yi Zhang, Wen-Juan Rui, Zhi-Qing Wang, Xia Fen. Quercetin alleviates chronic unpredictable mild stress-induced depressive-like behaviors by promoting adult hippocampal neurogenesis via FoxG1/CREB/ BDNF signaling pathway. Behavioural brain research. vol 406. 2021-09-02. PMID:33745981. |
in addition, to clarify the relationship between quercetin and ahn, we detected neurogenesis markers in the dentate gyrus (dg) of the hippocampus. |
2021-09-02 |
2023-08-13 |
mouse |
| Kathryn L Kern, Thomas W Storer, Karin Scho. Cardiorespiratory fitness, hippocampal subfield volumes, and mnemonic discrimination task performance in aging. Human brain mapping. vol 42. issue 4. 2021-08-31. PMID:33325614. |
aging and exercise have opposing effects on mnemonic discrimination task performance, which putatively taxes pattern separation mechanisms reliant on the dentate gyrus (dg) subfield of the hippocampus. |
2021-08-31 |
2023-08-13 |
Not clear |
| Kathryn L Kern, Thomas W Storer, Karin Scho. Cardiorespiratory fitness, hippocampal subfield volumes, and mnemonic discrimination task performance in aging. Human brain mapping. vol 42. issue 4. 2021-08-31. PMID:33325614. |
altogether, these findings provide further support for a role of the dg in behavioral pattern separation in humans and suggest that crf may have differential effects on hippocampal subfield integrity in older adult men and women. |
2021-08-31 |
2023-08-13 |
Not clear |
| N M Weston, A T Rolfe, A H Freelin, T M Reeves, D Su. Traumatic brain injury modifies synaptic plasticity in newly-generated granule cells of the adult hippocampus. Experimental neurology. vol 336. 2021-08-30. PMID:33188818. |
recent studies have found that tbi induces enhanced neurogenesis in the dentate gyrus (dg) of the hippocampus, and this cellular response is related to innate cognitive recovery. |
2021-08-30 |
2023-08-13 |
rat |
| Joanna Medina, Joanna L Workma. Maternal experience and adult neurogenesis in mammals: Implications for maternal care, cognition, and mental health. Journal of neuroscience research. vol 98. issue 7. 2021-08-26. PMID:30156028. |
the subventricular zone (svz) and dentate gyrus (dg) of the hippocampus undergo high rates of neurogenesis in adulthood and are sensitive to hormonal fluctuations. |
2021-08-26 |
2023-08-13 |
mouse |
| Xingrao Ke, Yingliu Huang, Qi Fu, Robert H Lane, Amber Majni. Adverse Maternal Environment Alters MicroRNA-10b-5p Expression and Its Epigenetic Profile Concurrently with Impaired Hippocampal Neurogenesis in Male Mouse Hippocampus. Developmental neuroscience. vol 43. issue 2. 2021-08-25. PMID:33940573. |
furthermore, ame significantly decreased hippocampal neurogenesis by decreasing cell numbers of ki67+ (proliferation marker), neurod1+ (neuronal differentiation marker), and neun+ (mature neuronal marker) in the dentate gyrus (dg) region concurrently with decreased hippocampal bdnf protein levels. |
2021-08-25 |
2023-08-13 |
mouse |
| Mora B Ogando, Olivia Pedroncini, Noel Federman, Sebastián A Romano, Luciano A Brum, Guillermo M Lanuza, Damian Refojo, Antonia Marin-Burgi. Cholinergic modulation of dentate gyrus processing through dynamic reconfiguration of inhibitory circuits. Cell reports. vol 36. issue 8. 2021-08-25. PMID:34433032. |
the dentate gyrus (dg) of the hippocampus plays a key role in memory formation, and it is known to be modulated by septal projections. |
2021-08-25 |
2023-08-13 |
Not clear |
| Anna Skórzewska, Małgorzata Lehner, Aleksandra Wisłowska-Stanek, Danuta Turzyńska, Alicja Sobolewska, Paweł Krząścik, Janusz Szyndler, Piotr Maciejak, Natalia Chmielewska, Karolina Kołosowska, Adam Płaźni. Individual susceptibility or resistance to posttraumatic stress disorder-like behaviours. Behavioural brain research. vol 386. 2021-08-24. PMID:32194190. |
ptsd(-) rats showed increased concentrations of corticosterone in plasma and changes in gad67 expression: decreased in the infralimbic cortex (il) and increased in the lateral amygdala (la), dentate gyrus (dg), and ca1 area of the hippocampus. |
2021-08-24 |
2023-08-13 |
rat |
| Anna Skórzewska, Małgorzata Lehner, Aleksandra Wisłowska-Stanek, Danuta Turzyńska, Alicja Sobolewska, Paweł Krząścik, Janusz Szyndler, Piotr Maciejak, Natalia Chmielewska, Karolina Kołosowska, Adam Płaźni. Individual susceptibility or resistance to posttraumatic stress disorder-like behaviours. Behavioural brain research. vol 386. 2021-08-24. PMID:32194190. |
the ptsd(+) group, compared to ptsd(-) rats, had decreased concentrations of corticosterone in plasma and reduced crf expression in the ppvn, higher crf expression in the ca1, increased expression of crf-positive nuclei and gr receptors in the ca3 area of the hippocampus, and increased expression of gr receptors in the dg and the central amygdala (cea). |
2021-08-24 |
2023-08-13 |
rat |
| Alexander V Maltsev, Pavel M Balaba. PP1/PP2A phosphatase inhibition-induced metaplasticity in protein synthesis blocker-treated hippocampal slices: LTP and LTD, or There and Back again. Biochemical and biophysical research communications. vol 558. 2021-08-23. PMID:33901925. |
prolonged exposure to anisomycin led to the no synthesis increase (measured using fluorescent dye) both in the dendrites and somata of ca1, ca3, dentate gyrus (dg) hippocampal layers. |
2021-08-23 |
2023-08-13 |
Not clear |
| Emanuele Mocciaro, Auston Grant, Rinat O Esenaliev, Irene Y Petrov, Yuriy Petrov, Stacy L Sell, Nicole L Hausser, Jutatip Guptarak, Elizabeth Bishop, Margaret A Parsley, Ian J Bolding, Kathia M Johnson, Maxwell Lidstone, Donald S Prough, Maria-Adelaide Micc. Non-Invasive Transcranial Nano-Pulsed Laser Therapy Ameliorates Cognitive Function and Prevents Aberrant Migration of Neural Progenitor Cells in the Hippocampus of Rats Subjected to Traumatic Brain Injury. Journal of neurotrauma. vol 37. issue 8. 2021-08-18. PMID:31856661. |
the hippocampus, one of the most affected brain region after tbi, plays a critical role in learning and memory and is one of the only two regions in the brain in which new neurons are generated throughout life from neural stem cells (nsc) in the dentate gyrus (dg). |
2021-08-18 |
2023-08-13 |
rat |
| Zahra Shabani, Mohsen Jafarzadeh Gharehziaaddi. Effects and Potential Mechanisms of Alcohol Use Disorder on the Fate Determination of Newly Born Neurons in the Hippocampus. Alcohol and alcoholism (Oxford, Oxfordshire). vol 55. issue 6. 2021-08-18. PMID:32814954. |
the subventricular zone (svz), lining the lateral ventricle, and the subgranular zone (sgz) in the dentate gyrus (dg) of the hippocampus are the two major neurogenic regions in the adult brain. |
2021-08-18 |
2023-08-13 |
Not clear |
| Shao-Han Chang, Ying Hao Yu, Alan He, Chen Yin Ou, Bai Chuang Shyu, Andrew Chih Wei Huan. BDNF Protein and BDNF mRNA Expression of the Medial Prefrontal Cortex, Amygdala, and Hippocampus during Situational Reminder in the PTSD Animal Model. Behavioural neurology. vol 2021. 2021-08-18. PMID:33763156. |
whether bdnf protein and bdnf mrna expression of the medial prefrontal cortex (mpfc; cingulated cortex area 1 (cg1), prelimbic cortex (prl), and infralimbic cortex (il)), amygdala, and hippocampus (ca1, ca2, ca3, and dentate gyrus (dg)) was involved in fear of posttraumatic stress disorder (ptsd) during the situational reminder of traumatic memory remains uncertain. |
2021-08-18 |
2023-08-13 |
rat |