| Publication |
Sentence |
Publish Date |
Extraction Date |
Species |
| Bai-Chuang Shyu, Zhi-Yue Gao, José Jiun-Shian Wu, Alan Bo Han He, Cai-N Cheng, Andrew Chih Wei Huan. Methamphetamine and Modulation Functionality of the Prelimbic Cortex for Developing a Possible Treatment of Alzheimer's Disease in an Animal Model. Frontiers in aging neuroscience. vol 13. 2021-11-10. PMID:34744692. |
the mpfc, and particularly the prl and il and the dg of the hippocampus, appeared to show increased neural activity in c-fos expression or neural plasticity in p-erk expression. |
2021-11-10 |
2023-08-13 |
rat |
| Andrew J Kwilasz, Laurel S Todd, Julissa C Duran-Malle, Anouk E W Schrama, Eric H Mitten, Tracey A Larson, Madison A Clements, Kevin M Harris, Scott T Litwiler, Xiaohui Wang, Anne-Marie Van Dam, Steven F Maier, Kenner C Rice, Linda R Watkins, Ruth M Barriento. Experimental autoimmune encephalopathy (EAE)-induced hippocampal neuroinflammation and memory deficits are prevented with the non-opioid TLR2/TLR4 antagonist (+)-naltrexone. Behavioural brain research. vol 396. 2021-11-09. PMID:32905811. |
this was associated with increased mrna for hippocampal interleukin-1β (il-1β), tlr2, tlr4, nlrp3, and il-17 and elevated expression of the microglial marker iba1 in ca1 and dg regions of the hippocampus, confirming the neuroinflammation observed in higher-dose eae models. |
2021-11-09 |
2023-08-13 |
human |
| Mohammad Alipour, Mina Kamkar Asl, Elnaz Khordad, Fatemeh Alipour, Amir Raoofi, Alireza Ebrahimzadeh-Bideskan, Vahid Ebrahim. Histopathological study on neuroapoptotic alterations induced by etomidate in rat hippocampus. Acta histochemica. vol 123. issue 3. 2021-11-08. PMID:33601320. |
our results showed that the number of tunel positive cells and dark neurons (dns) in etomidate group were significantly higher in the ca1, ca2, ca3, and dentate gyrus (dg) of hippocampus compared with the control and normal groups (p < 0.05). |
2021-11-08 |
2023-08-13 |
human |
| Mohammad Alipour, Mina Kamkar Asl, Elnaz Khordad, Fatemeh Alipour, Amir Raoofi, Alireza Ebrahimzadeh-Bideskan, Vahid Ebrahim. Histopathological study on neuroapoptotic alterations induced by etomidate in rat hippocampus. Acta histochemica. vol 123. issue 3. 2021-11-08. PMID:33601320. |
our findings showed that etomidate can increase apoptotic cells and dark neurons induction in different regions of hippocampus mainly in dg. |
2021-11-08 |
2023-08-13 |
human |
| Ye Li, Cuiqin Fan, Liyan Wang, Tian Lan, Rui Gao, Wenjing Wang, Shu Yan Y. MicroRNA-26a-3p rescues depression-like behaviors in male rats via preventing hippocampal neuronal anomalies. The Journal of clinical investigation. vol 131. issue 16. 2021-11-08. PMID:34228643. |
in the present study, we screened microrna (mirna) expression profiles in the dentate gyrus (dg) of the hippocampus and found that mir-26a-3p was markedly downregulated in a rat model of depression, whereas upregulation of mir-26a-3p within dg regions rescued the neuronal deterioration and depression-like phenotypes resulting from stress exposure, effects that appear to be mediated by the pten pathway. |
2021-11-08 |
2023-08-13 |
rat |
| Ye Li, Cuiqin Fan, Liyan Wang, Tian Lan, Rui Gao, Wenjing Wang, Shu Yan Y. MicroRNA-26a-3p rescues depression-like behaviors in male rats via preventing hippocampal neuronal anomalies. The Journal of clinical investigation. vol 131. issue 16. 2021-11-08. PMID:34228643. |
in conclusion, these results suggest that mir-26a-3p deficits within the hippocampal dg mediated the neuronal anomalies contributing to the display of depression-like behaviors. |
2021-11-08 |
2023-08-13 |
rat |
| Wenhua Xu, Hui Li, Caigu He, Jacqueline Frank, Gang Che. Early Ethanol Exposure Inhibits the Differentiation of Hippocampal Dentate Gyrus Granule Cells in a Mouse Model of Fetal Alcohol Spectrum Disorders. Alcoholism, clinical and experimental research. vol 44. issue 5. 2021-11-04. PMID:32220014. |
the hippocampal formation is critically involved in spatial learning/memory and contains 2 major neuron populations: the pyramidal cells in the hippocampus proper and the dentate gyrus granule cells (dggcs) in the dentate gyrus (dg). |
2021-11-04 |
2023-08-13 |
mouse |
| I G Shalaginova, O P Tuchina, M V Sidorova, A S Levina, D A-A Khlebaeva, A I Vaido, N A Dyuzhikov. Effects of psychogenic stress on some peripheral and central inflammatory markers in rats with the different level of excitability of the nervous system. PloS one. vol 16. issue 7. 2021-11-03. PMID:34324596. |
highly excitable animals show an increase in anxiety-like behavior, in the number of neutrophils compared to lymphocytes as well as in the number of iba1+ cells in ca1, ca3 and dg areas of the hippocampus in response to stress. |
2021-11-03 |
2023-08-13 |
rat |
| Munekazu Komada, Tetsuji Nagao, Nao Kagaw. Postnatal di-2-ethylhexyl phthalate exposure affects hippocampal dentate gyrus morphogenesis. Journal of applied toxicology : JAT. vol 40. issue 12. 2021-11-02. PMID:32633424. |
we found that in mice, postnatal dehp exposure led to a decrease in the number of type-1, -2a, -2b, and -3 neural progenitor cells, as well as granule cells in the hippocampal dg at pnd 26. |
2021-11-02 |
2023-08-13 |
mouse |
| Munekazu Komada, Tetsuji Nagao, Nao Kagaw. Postnatal di-2-ethylhexyl phthalate exposure affects hippocampal dentate gyrus morphogenesis. Journal of applied toxicology : JAT. vol 40. issue 12. 2021-11-02. PMID:32633424. |
further, the results showed that neural progenitor cell proliferation and differentiation were also reduced in the hippocampal dg of the dehp-exposed mice. |
2021-11-02 |
2023-08-13 |
mouse |
| Jing Zhang, Lanyan Lin, Xiaoman Dai, Nai'an Xiao, Qinyong Ye, Xiaochun Che. ApoE4 increases susceptibility to stress-induced age-dependent depression-like behavior and cognitive impairment. Journal of psychiatric research. vol 143. 2021-11-02. PMID:34530340. |
stress induced a loss of gabaergic neurons and decline of reelin level in the prefrontal cortex (pfc) and in the dentate gyrus (dg) of the hippocampus in both 3-month-old and 8-month-old apoe-tr mice, which were more pronounced in the 8-month-old apoe4-tr mice. |
2021-11-02 |
2023-08-13 |
mouse |
| Karina Alviña, Mohammad Jodeiri Farshbaf, Amit Kumar Monda. Long term effects of stress on hippocampal function: Emphasis on early life stress paradigms and potential involvement of neuropeptide Y. Journal of neuroscience research. vol 99. issue 1. 2021-11-01. PMID:32162350. |
the hippocampal dentate gyrus (dg)-ca3 circuit, composed of dg granule cells axons (mossy fibers) synapsing onto ca3 pyramidal cells, plays an essential role in memory encoding and retrieval, functions that are vulnerable to stress. |
2021-11-01 |
2023-08-13 |
Not clear |
| Yubin Wang, Yan Liu, Emad Yahya, Diana Quach, Xiaoning Bi, Michel Baudr. Calpain-2 activation in mouse hippocampus plays a critical role in seizure-induced neuropathology. Neurobiology of disease. vol 147. 2021-11-01. PMID:33132163. |
neurodegeneration was evident in various hippocampal subfields, in particular in mossy cells in the hilus of the dentate gyrus (dg) in c57/bl6 mice 7 days after kainic acid (ka)-induced seizures. |
2021-11-01 |
2023-08-13 |
mouse |
| Zhiyong Zhao, Lei Zhang, Qingqing Wen, Wanrong Luo, Weihao Zheng, Tingting Liu, Yi Zhang, Keqing Zhu, Dan W. The effect of beta-amyloid and tau protein aggregations on magnetic susceptibility of anterior hippocampal laminae in Alzheimer's diseases. NeuroImage. vol 244. 2021-11-01. PMID:34537383. |
we manually segmented each sample into seven layers, including four layers in the cornu ammonis1 (ca1) and three layers in the dentate gyrus (dg), and then evaluated ad-related alterations of susceptibility and t2* values and their correlations with aβ and tau in each hippocampal layer. |
2021-11-01 |
2023-08-13 |
Not clear |
| Zongxia Lv, Zirong Chen, Wei Ye, Xiaomin Pang, Liluo Nie, Weiwei Chang, Qijia Long, Jinou Zhen. Disruption in Surface-Based Functional Connectivity in the Right Posterior Hippocampal CA3 Subfield: A Probable Neural Basis of Visuospatial Working Memory Impairment in Patients With Right Temporal Lobe Epilepsy. Frontiers in neurology. vol 12. 2021-10-30. PMID:34712198. |
the right posterior hippocampus was automatically segmented, and the surface-based functional connectivity (sbfc) of the subiculum (sub), ca1, ca3, dentate gyrus (dg), hippocampal tail, and right entorhinal cortex (ec) were compared between groups. |
2021-10-30 |
2023-08-13 |
Not clear |
| Dan Xu, Fengyang Li, Gou Xue, Kai Hou, Weirong Fang, Yunman L. Effect of Wnt signaling pathway on neurogenesis after cerebral ischemia and its therapeutic potential. Brain research bulletin. vol 164. 2021-10-29. PMID:32763283. |
neurogenesis process in the chronic phase of ischemic stroke has become the focus of research on stroke treatment recently, mainly through the activation of related pathways to increase the differentiation of neural stem cells (nscs) in the brain sub-ventricular zone (svz) and subgranular zone (sgz) of hippocampal dentate gyrus (dg) areas into neurons, promoting neurogenesis. |
2021-10-29 |
2023-08-13 |
Not clear |
| Gaëtan Philippot, Sofie V Hellsten, Henrik Viberg, Robert Fredriksso. Evaluation of the dentate gyrus in adult mice exposed to acetaminophen (paracetamol) on postnatal day 10. International journal of developmental neuroscience : the official journal of the International Society for Developmental Neuroscience. vol 81. issue 1. 2021-10-28. PMID:33222217. |
we did not observe any visual effects in adult dg cytoarchitecture, nor any changes of markers for differentiation/migration in the hippocampus in 24 hr after exposure. |
2021-10-28 |
2023-08-13 |
mouse |
| Olga Krupska, Tomasz Kowalczyk, Małgorzata Beręsewicz-Haller, Paulina Samczuk, Karolina Pietrowska, Krzysztof Zabłocki, Adam Kretowski, Michal Ciborowski, Barbara Zabłock. Hippocampal Sector-Specific Metabolic Profiles Reflect Endogenous Strategy for Ischemia-Reperfusion Insult Resistance. Molecular neurobiology. vol 58. issue 4. 2021-10-27. PMID:33222147. |
the ca1 of the hippocampus is vulnerable to 5 min of ischemia, while the ca2-4 and dentate gyrus (dg) are resistant to it. |
2021-10-27 |
2023-08-13 |
Not clear |
| Bolanle Fatimat Olabiyi, Catherine Fleitas, Bahira Zammou, Isidro Ferrer, Claire Rampon, Joaquim Egea, Carme Espine. proNGF Involvement in the Adult Neurogenesis Dysfunction in Alzheimer's Disease. International journal of molecular sciences. vol 22. issue 19. 2021-10-25. PMID:34639085. |
interestingly, work with rodents has shown that adult neurogenesis in the dentate gyrus (dg) of the hippocampus is vital for some cognitive aspects, as increasing neurogenesis improves memory, while its disruption triggers the opposite effect. |
2021-10-25 |
2023-08-13 |
mouse |
| Antoine Bouyeure, Sandesh Patil, Franck Mauconduit, Clément Poiret, Damien Isai, Marion Noulhian. Hippocampal subfield volumes and memory discrimination in the developing brain. Hippocampus. vol 31. issue 11. 2021-10-22. PMID:34448509. |
ps is known to rely on the hippocampus, particularly on hippocampal subfields dg and ca3. |
2021-10-22 |
2023-08-13 |
Not clear |