Publication |
Sentence |
Publish Date |
Extraction Date |
Species |
Marie-Gabrielle Goossens, Lars Emil Larsen, Marijke Vergaelen, Wytse Wadman, Chris Van den Haute, Wayra Brackx, Silke Proesmans, Jana Desloovere, Emma Christiaen, Erine Craey, Christian Vanhove, Kristl Vonck, Paul Boon, Robrecht Raed. Level of hM4D(Gi) DREADD Expression Determines Inhibitory and Neurotoxic Effects in the Hippocampus. eNeuro. vol 8. issue 6. 2021-12-10. PMID:34620623. |
our results indicate that prolonged, high levels of dreadd expression can have neurotoxic effects and that chemogenetic suppression of excitatory hippocampal neurons can paradoxically enhance dg evoked potentials. |
2021-12-10 |
2023-08-13 |
rat |
Alexey A Kulikov, Alexandra A Naumova, Ekaterina P Aleksandrova, Margarita V Glazova, Elena V Chernigovskay. Audiogenic kindling stimulates aberrant neurogenesis, synaptopodin expression, and mossy fiber sprouting in the hippocampus of rats genetically prone to audiogenic seizures. Epilepsy & behavior : E&B. vol 125. 2021-12-10. PMID:34837844. |
however, after 21 ags increased proliferation was observed only in the dg, while the numbers of immature neurons expressed vglut1/2 were still enhanced in both hippocampal areas. |
2021-12-10 |
2023-08-13 |
rat |
Ruike Wang, Zuntao Wu, Mengchen Liu, Yingying Wu, Qiong Li, Yue Ba, Huizhen Zhang, Xuemin Cheng, Guoyu Zhou, Hui Huan. Resveratrol reverses hippocampal synaptic markers injury and SIRT1 inhibition against developmental Pb exposure. Brain research. vol 1767. 2021-12-09. PMID:34175265. |
the dg, ca1 and ca3 regions of the hippocampus showed a considerable increase in the expression of pre- and postsynaptic proteins (p < 0.001 vs 0.2% pb group). |
2021-12-09 |
2023-08-13 |
rat |
Jehoon Lee, Vishal Naik, Marcus Orzabal, Raine Lunde-Young, Jayanth Ramados. Morphological alteration in rat hippocampal neuronal dendrites following chronic binge prenatal alcohol exposure. Brain research. vol 1768. 2021-12-09. PMID:34297994. |
pae increased dendritic arborization and complexities of ca1, ca2/3, and dg neurons in the pnd 10 rat hippocampus. |
2021-12-09 |
2023-08-13 |
rat |
Dongmeng Liu, Dahui Xue, Wencan Lu, Zhuochun Yang, Li Li, Beibei Xia, Jinhua Wei, Xianxiong Chen, Yi Yang, Xiaomei Wang, Guimiao Li. BDE-47 induced PC-12 cell differentiation via TrkA downstream pathways and caused the loss of hippocampal neurons in BALB/c mice. Journal of hazardous materials. vol 422. 2021-12-06. PMID:34419847. |
h&e staining of brain showed neurons in dg and ca1 areas of hippocampus decreased after bde-47 exposure. |
2021-12-06 |
2023-08-13 |
mouse |
Sandra De la Torre-Iturbe, Rubén Antonio Vázquez-Roque, Fidel de la Cruz-López, Gonzalo Flores, Linda Garcés-Ramíre. Dendritic and behavioral changes in rats neonatally treated with homocysteine; A proposal as an animal model to study the attention deficit hyperactivity disorder. Journal of chemical neuroanatomy. 2021-12-06. PMID:34871732. |
morphological changes were found mainly in the shape of dendritic spines in the prefrontal cortex (pfc-3), dorsal hippocampus (ca1), dentate gyrus (dg) and nucleus accumbens (nacc), in rats administered neonatally with homocysteine at both ages studied. |
2021-12-06 |
2023-08-13 |
rat |
He Huang, Chao Zhao, Qian Hu, Qiang Liu, Yi-Man Sun, Chen Chen, Hui Huang, Cheng-Hua Zhou, Yu-Qing W. Neonatal Anesthesia by Ketamine in Neonatal Rats Inhibits the Proliferation and Differentiation of Hippocampal Neural Stem Cells and Decreases Neurocognitive Function in Adulthood via Inhibition of the Notch1 Signaling Pathway. Molecular neurobiology. vol 58. issue 12. 2021-12-03. PMID:34480336. |
notch ligand jagged1 (0.5 mg/kg) and lentivirus overexpressing the notch1 intracellular domain (lv-nicd1) were microinjected into the hippocampal dentate gyrus (dg) 1 h or 4 days before ketamine administration, respectively. |
2021-12-03 |
2023-08-13 |
rat |
He Huang, Chao Zhao, Qian Hu, Qiang Liu, Yi-Man Sun, Chen Chen, Hui Huang, Cheng-Hua Zhou, Yu-Qing W. Neonatal Anesthesia by Ketamine in Neonatal Rats Inhibits the Proliferation and Differentiation of Hippocampal Neural Stem Cells and Decreases Neurocognitive Function in Adulthood via Inhibition of the Notch1 Signaling Pathway. Molecular neurobiology. vol 58. issue 12. 2021-12-03. PMID:34480336. |
the proliferation and differentiation of the neural stem cells (nscs) in the hippocampal dg were evaluated by double immunofluorescence staining 24 h after treatment. |
2021-12-03 |
2023-08-13 |
rat |
He Huang, Chao Zhao, Qian Hu, Qiang Liu, Yi-Man Sun, Chen Chen, Hui Huang, Cheng-Hua Zhou, Yu-Qing W. Neonatal Anesthesia by Ketamine in Neonatal Rats Inhibits the Proliferation and Differentiation of Hippocampal Neural Stem Cells and Decreases Neurocognitive Function in Adulthood via Inhibition of the Notch1 Signaling Pathway. Molecular neurobiology. vol 58. issue 12. 2021-12-03. PMID:34480336. |
microinjection of jagged1 or lv-nicd1 reversed the inhibitory effect of ketamine on the expression of notch1-related proteins in the hippocampal dg, attenuated the ketamine-mediated decrease in nsc proliferation and differentiation, and improved the cognitive function of 2-month-old rats after neonatal exposure to ketamine. |
2021-12-03 |
2023-08-13 |
rat |
James Delorme, Lijing Wang, Femke Roig Kuhn, Varna Kodoth, Jingqun Ma, Jessy D Martinez, Frank Raven, Brandon A Toth, Vinodh Balendran, Alexis Vega Medina, Sha Jiang, Sara J Ato. Sleep loss drives acetylcholine- and somatostatin interneuron-mediated gating of hippocampal activity to inhibit memory consolidation. Proceedings of the National Academy of Sciences of the United States of America. vol 118. issue 32. 2021-12-01. PMID:34344824. |
we find that ps6 is enhanced in dentate gyrus (dg) following single-trial contextual fear conditioning (cfc) but is reduced throughout the hippocampus after brief sleep deprivation (sd; which disrupts contextual fear memory [cfm] consolidation). |
2021-12-01 |
2023-08-13 |
mouse |
Gaifen Li, Jia Liu, Yuying Guan, Xunming J. The role of hypoxia in stem cell regulation of the central nervous system: From embryonic development to adult proliferation. CNS neuroscience & therapeutics. vol 27. issue 12. 2021-12-01. PMID:34817133. |
the subventricular zone (svz) and hippocampal dentate gyrus (dg) are the main sites of adult neurogenesis in the brain. |
2021-12-01 |
2023-08-13 |
Not clear |
Juan D Rodriguez-Callejas, Eberhard Fuchs, Claudia Perez-Cru. Increased oxidative stress, hyperphosphorylation of tau, and dystrophic microglia in the hippocampus of aged Tupaia belangeri. Glia. vol 68. issue 9. 2021-11-30. PMID:32096580. |
with aging, oxidative damage to rna (8ohg) increased significantly in all hippocampal regions, while tau hyperphosphorylation (at100) was enhanced in dg, ca3, and sub in aged animals. |
2021-11-30 |
2023-08-13 |
Not clear |
Olga Netsyk, Hayma Hammoud, Sergiy V Korol, Zhe Jin, Atieh S Tafreshiha, Bryndis Birni. Tonic GABA-activated synaptic and extrasynaptic currents in dentate gyrus granule cells and CA3 pyramidal neurons along the mouse hippocampal dorsoventral axis. Hippocampus. vol 30. issue 11. 2021-11-26. PMID:32533811. |
we have examined in two cell-types of the hippocampal projection neurons, the dentate gyrus (dg) granule cells and ca3 pyramidal neurons, if the gaba-activated tonic current density varied between the dorsal (septal) and the ventral (temporal) poles of the male mouse hippocampus. |
2021-11-26 |
2023-08-13 |
mouse |
Marco Carli, Stefano Aringhieri, Shivakumar Kolachalam, Biancamaria Longoni, Giovanna Grenno, Mario Rossi, Angelo Gemignani, Francesco Fornai, Roberto Maggio, Marco Scarsell. Is Adult Hippocampal Neurogenesis Really Relevant for the Treatment of Psychiatric Disorders? Current neuropharmacology. vol 19. issue 10. 2021-11-25. PMID:32811415. |
in mammals, this process is limited to very few areas of the brain, and one of these neurogenic niches is the subgranular layer of the dentate gyrus (dg) of the hippocampus. |
2021-11-25 |
2023-08-13 |
human |
Antônio Márcio Rodrigues, Delmo Benedito Silva, Maísa Ferreira Miranda, Silvia Cristina Braga da Silva, Luiz Eduardo Canton Santos, Fulvio Alexandre Scorza, Carla Alessandra Scorza, Marcelo A Moret, Antônio-Carlos Guimarães de Almeid. The Effect of Low Magnesium Concentration on Ictal Discharges In A Non-Synaptic Model. International journal of neural systems. vol 31. issue 4. 2021-11-24. PMID:33357154. |
as an experimental protocol, nsea were induced in rat hippocampal dentate gyrus (dg), using a bath solution containing high-k[formula: see text] and zero-added-ca[formula: see text]. |
2021-11-24 |
2023-08-13 |
rat |
Olayemi Joseph Olajide, Ismail Tayo Gbadamosi, Emmanuel Olusola Yawson, Tolulope Arogundade, Folashade Susan Lewu, Kehinde Yomi Ogunrinola, Oluwaseun Olaniyi Adigun, Olawande Bamisi, Ezra Lambe, Leviticus Ogbenevurinrin Arietarhire, Olushola Oladapo Oluyomi, Olumayowa Kolawole Idowu, Rukayat Kareem, Nnaemeka Tobechukwu Asogwa, Philip Adeyemi Adeniy. Hippocampal Degeneration and Behavioral Impairment During Alzheimer-Like Pathogenesis Involves Glutamate Excitotoxicity. Journal of molecular neuroscience : MN. vol 71. issue 6. 2021-11-23. PMID:33420680. |
here, we investigated the acute effects of stereotaxic dentate gyrus (dg) glutamate injection on behavior and molecular expression of specific proteins and neurochemicals modulating hippocampal functions. |
2021-11-23 |
2023-08-13 |
rat |
Joaquín González Fuentes, Ricardo Insausti Serrano, Sandra Cebada Sánchez, Maria José Lagartos Donate, Eloy Rivas Infante, María Del Mar Arroyo Jiménez, María Del Pilar Marcos Raba. Neuropeptides in the developing human hippocampus under hypoxic-ischemic conditions. Journal of anatomy. vol 239. issue 4. 2021-11-23. PMID:34028021. |
two rostrocaudal sections of the body of the hippocampus were analysed, and the number of immunostained cells in the polymorphic layer of the dentate gyrus (dg) and the pyramidal cell layer and stratum oriens of the ca3, ca2 and ca1 fields of the hippocampus proper were quantified. |
2021-11-23 |
2023-08-13 |
human |
Heng Zhang, Ling Zhang, Dongming Zhou, Hongfei Li, Yang X. ErbB4 mediates amyloid β-induced neurotoxicity through JNK/tau pathway activation: Implications for Alzheimer's disease. The Journal of comparative neurology. vol 529. issue 15. 2021-11-23. PMID:34212389. |
moreover, specific ablation of erbb4 in pv neurons altered activity-related protein c-fos and decreased hippocampal pv neurons, especially in the dentate gyrus (dg) of happ-j20 mice. |
2021-11-23 |
2023-08-13 |
mouse |
b' Lili Sahakyan, Tina Meller, Ulrika Evermann, Simon Schmitt, Julia-Katharina Pfarr, Jens Sommer, Thomas R Kwapil, Igor Nenadi\\xc4\\x8. Anterior vs Posterior Hippocampal Subfields in an Extended Psychosis Phenotype of Multidimensional Schizotypy in a Nonclinical Sample. Schizophrenia bulletin. vol 47. issue 1. 2021-11-19. PMID:32691055.' |
hippocampal subfields were analyzed from high-resolution 3 tesla structural magnetic resonance imaging scans testing anatomical models, including anterior vs posterior regions and the cornu ammonis (ca), dentate gyrus (dg), and subiculum subfields separately for the left and right hemispheres. |
2021-11-19 |
2023-08-13 |
human |
b' Lili Sahakyan, Tina Meller, Ulrika Evermann, Simon Schmitt, Julia-Katharina Pfarr, Jens Sommer, Thomas R Kwapil, Igor Nenadi\\xc4\\x8. Anterior vs Posterior Hippocampal Subfields in an Extended Psychosis Phenotype of Multidimensional Schizotypy in a Nonclinical Sample. Schizophrenia bulletin. vol 47. issue 1. 2021-11-19. PMID:32691055.' |
the interaction of negative and disorganized schizotypy robustly predicted left hemisphere volumetric reductions for the anterior and total hippocampus, and anterior ca and dg, and the largest reductions were seen in participants high in negative and disorganized schizotypy. |
2021-11-19 |
2023-08-13 |
human |