| Publication |
Sentence |
Publish Date |
Extraction Date |
Species |
| L A Kelly, R W Butche. Effects of delta 1-tetrahydrocannabinol on cyclic AMP in cultured human diploid fibroblasts. Journal of cyclic nucleotide research. vol 5. issue 4. 1980-01-19. PMID:91629. |
cannabidiol acted similar to delta 1-thc in affecting cyclic amp metabolis whereas cannabinol and cannabicyclol showed mixed effects on the various parameters studied. |
1980-01-19 |
2023-08-11 |
human |
| P Chiu, D M Olsen, H K Borys, R Karler, S A Turkani. The influence of cannabidiol and delta 9-tetrahydrocannabinol on cobalt epilepsy in rats. Epilepsia. vol 20. issue 4. 1979-11-29. PMID:113206. |
the influence of cannabidiol and delta 9-tetrahydrocannabinol on cobalt epilepsy in rats. |
1979-11-29 |
2023-08-11 |
rat |
| P Chiu, D M Olsen, H K Borys, R Karler, S A Turkani. The influence of cannabidiol and delta 9-tetrahydrocannabinol on cobalt epilepsy in rats. Epilepsia. vol 20. issue 4. 1979-11-29. PMID:113206. |
the mechanisms of the anticonvulsant activity of cannabidiol (cbd) and the central excitation of delta 9-tetrahydrocannabinol (delta 9-thc) were investigated electrophysiologically with conscious, unrestrained cobalt epileptic rats. |
1979-11-29 |
2023-08-11 |
rat |
| S A Turkanis, K A Smiley, H K Borys, D M Olsen, R Karle. An electrophysiological analysis of the anticonvulsant action of cannabidiol on limbic seizures in conscious rats. Epilepsia. vol 20. issue 4. 1979-11-29. PMID:477630. |
the effects of cannabidiol (cbd) on electrically evoked kindled seizures were studied in conscious, unrestrained rats with chronically implanted cortical and limbic electrodes, and the results were compared with those of delta 9-tetrahydrocannabinol (delta 9-thc), phenytoin (pht), and ethosuximide (esm). |
1979-11-29 |
2023-08-11 |
rat |
| J M Carney, R L Balster, B R Martin, L S Harri. Effects of systemic and intraventricular administration of cannabinoids on schedule-controlled responding in the squirrel monkey. The Journal of pharmacology and experimental therapeutics. vol 210. issue 3. 1979-11-28. PMID:113528. |
the order of potency was (+/-)-9-nor-9 beta-oh hexahydrocannabinol, 11-oh-delta 9-tetrahydrocannabinol, delta 9-tetrahydrocannabinol (delta 9-thc), cannabinol and cannabidiol. |
1979-11-28 |
2023-08-11 |
monkey |
| G Fournier, P M Lenicque, M R Pari. [Toxic effects of essential oil of Cannabis sativa L. and main constituents on planarian (Dugesia tigrina) (author's transl)]. Toxicological European research. Recherche europeenne en toxicologie. vol 1. issue 6. 1979-10-26. PMID:754350. |
it was not possible to detect any protection by 5-hydroxytryptamine as it was the case against delta 1-tétrahydro-cannabinol and cannabidiol. |
1979-10-26 |
2023-08-11 |
Not clear |
| H K Borys, R Karle. Cannabidiol and delta 9-tetrahydrocannabinol metabolism. In vitro comparison of mouse and rat liver crude microsome preparations. Biochemical pharmacology. vol 28. issue 9. 1979-10-17. PMID:475867. |
cannabidiol and delta 9-tetrahydrocannabinol metabolism. |
1979-10-17 |
2023-08-11 |
mouse |
| J A Jacobs, A J Dellarco, R A Manfredi, J Harclerod. The effects of delta 9-tetrahydrocannabinol, cannabidiol, and shock on plasma corticosterone concentrations in rats. The Journal of pharmacy and pharmacology. vol 31. issue 5. 1979-09-17. PMID:37310. |
the effects of delta 9-tetrahydrocannabinol, cannabidiol, and shock on plasma corticosterone concentrations in rats. |
1979-09-17 |
2023-08-11 |
rat |
| J Sanders, D M Jackson, G A Starme. Interactions among the cannabinoids in the antagonism of the abdominal constriction response in the mouse. Psychopharmacology. vol 61. issue 3. 1979-08-16. PMID:156380. |
the ability of delta 9-tetrahydrocannabinol (thc), cannabinol (cbn), cannabidiol (cbd), 11-oh thc and 8 alpha, 11-dioh thc to antagonise the abdominal constriction response in the mouse induced by formic acid, phenylquinone, 5-hydroxytryptamine, prostaglandin e1 (pge1) and bradykinin was tested. |
1979-08-16 |
2023-08-11 |
mouse |
| P L Clopton, D S Janowsky, J M Clopton, L L Judd, L Hue. Marijuana and the perception of affect. Psychopharmacology. vol 61. issue 2. 1979-07-25. PMID:108738. |
subjects smoked either placebo or active marijuana containing 6 mg delta 9-thc. |
1979-07-25 |
2023-08-11 |
human |
| A Lecorsier, H Hoellinger, Nguyen-Hoang-Nam, E Fournie. [Allergenic character of tetrahydrocannabinol (delta 9 THC), active principle of Indian hemp (Cannabis saliva var. indica)]. Comptes rendus hebdomadaires des seances de l'Academie des sciences. Serie D: Sciences naturelles. vol 285. issue 15. 1978-04-26. PMID:414851. |
[allergenic character of tetrahydrocannabinol (delta 9 thc), active principle of indian hemp (cannabis saliva var. |
1978-04-26 |
2023-08-11 |
Not clear |
| J Frizza, G B Chesher, D M Jackson, R Malor, G A Starme. The effect of delta 9-tetrahydrocannabinol, cannabidiol, and cannabinol on the anaesthesia induced by various anaesthetic agents in mice. Psychopharmacology. vol 55. issue 1. 1978-03-10. PMID:414255. |
the effect of delta 9-tetrahydrocannabinol, cannabidiol, and cannabinol on the anaesthesia induced by various anaesthetic agents in mice. |
1978-03-10 |
2023-08-11 |
mouse |
| J Frizza, G B Chesher, D M Jackson, R Malor, G A Starme. The effect of delta 9-tetrahydrocannabinol, cannabidiol, and cannabinol on the anaesthesia induced by various anaesthetic agents in mice. Psychopharmacology. vol 55. issue 1. 1978-03-10. PMID:414255. |
the interaction of delta 9-tetrahydrocannabinol with the anaesthetic agents was postulated to be due to a centrally mediated action, whereas the effect of cannabidiol on pentobarbitone-induced anaesthesia probably depended on a metabolic interaction. |
1978-03-10 |
2023-08-11 |
mouse |
| D J Harvey, B R Martin, W D Pato. In vivo metabolism of cannabinol by the mouse and rat and a comparison with a metabolism of delta 1-tetrahydrocannabinol and cannabidiol. Biomedical mass spectrometry. vol 4. issue 6. 1978-03-10. PMID:597586. |
in vivo metabolism of cannabinol by the mouse and rat and a comparison with a metabolism of delta 1-tetrahydrocannabinol and cannabidiol. |
1978-03-10 |
2023-08-11 |
mouse |
| M P Maskarinec, G Shipley, M Novotny, D J Brown, R B Forne. Different effects of synthetic delta 9-tetrahydrocannabinol and cannabis extract on steroid metabolism in male rats. Experientia. vol 34. issue 1. 1978-03-10. PMID:620748. |
different effects of synthetic delta 9-tetrahydrocannabinol and cannabis extract on steroid metabolism in male rats. |
1978-03-10 |
2023-08-11 |
rat |
| P Consroe, A Wolki. Cannabidiol--antiepileptic drug comparisons and interactions in experimentally induced seizures in rats. The Journal of pharmacology and experimental therapeutics. vol 201. issue 1. 1977-05-27. PMID:850145. |
a comparison of the anticonvulsant and neurotoxic effects of cannabidiol (cbd), delta 9tetrahydrocannabinol, cannabinol and antiepileptic drugs (phenytoin, phenobarbital, carbamazepine, chlordiazepoxide, clonazepam, ethosuximide and trimethadione) was made in rats. |
1977-05-27 |
2023-08-11 |
rat |
| L Miller, T Cornett, D Brightwell, D McFarland, W G Drew, A Wikle. Marijuana and memory impairment: the effect of retrieval cues on free recall. Pharmacology, biochemistry, and behavior. vol 5. issue 6. 1977-05-25. PMID:1023232. |
in an attempt to ascertain the effect of retrieval cues on recall deficits which occur following intoxication with marijuana, 40 male volunteers were presented with word lists following the smoking of a single one gram marijuana (0.94% delta 9 -thc) or placebo cigarette and then were required to recall these words immediately after presentation. |
1977-05-25 |
2023-08-11 |
human |
| A Wikle. Aspects of tolerance to and dependence on cannabis. Annals of the New York Academy of Sciences. vol 282. 1977-04-25. PMID:828472. |
"dispositional tolerance" (increased rate of metabolism of delta 9-thc due to enzyme induction) may play a role in the development of tolerance or "reverse tolerance" to cannabis in man. |
1977-04-25 |
2023-08-11 |
monkey |
| A Wikle. Aspects of tolerance to and dependence on cannabis. Annals of the New York Academy of Sciences. vol 282. 1977-04-25. PMID:828472. |
dependence on cannabis, in the sense of abstinence phenomena on abrupt withdrawal of delta 9-thc, has been demonstrated in monkeys made tolerant to delta 9-thc given four times daily for about 1 month. |
1977-04-25 |
2023-08-11 |
monkey |
| A Wikle. Aspects of tolerance to and dependence on cannabis. Annals of the New York Academy of Sciences. vol 282. 1977-04-25. PMID:828472. |
in the west, where marijuana with relatively low delta 9-thc content is widely smoked, dependence in the sense of drug-seeking behavior appears to be less a function of any pharmacologic reinforcing properties the drug may have than of secondary (conditioned) reinforcement derived from the social milieu in which the marijuana is smoked. |
1977-04-25 |
2023-08-11 |
monkey |