| Publication |
Sentence |
Publish Date |
Extraction Date |
Species |
| C J Hillard, A S Bloo. Possible role of prostaglandins in the effects of the cannabinoids on adenylate cyclase activity. European journal of pharmacology. vol 91. issue 1. 1983-11-23. PMID:6311573. |
in vitro, the cannabinoids delta 9-tetrahydrocannabinol (delta 9-thc), 11-oh-delta 9-thc, cannabidiol and cannabinol all increased adenylate cyclase activity in mouse cerebral cortical homogenates. |
1983-11-23 |
2023-08-12 |
mouse |
| K T Churchil. Synthetic tetrahydrocannabinol. Journal of forensic sciences. vol 28. issue 3. 1983-11-23. PMID:6311937. |
this paper presents the synthetic route used and the identification of the precursors and reaction products in a clandestine laboratory manufacture of cannabidiol (cbd), delta 9-cis-tetrahydrocannabinol (delta 9-cis-thc), and delta 9-trans-tetrahydrocannabinol (delta 9-trans-thc). |
1983-11-23 |
2023-08-12 |
Not clear |
| J E Lindgre. Quantification of delta 1-tetrahydrocannabinol in tissues and body fluids. Archives of toxicology. Supplement. = Archiv fur Toxikologie. Supplement. vol 6. 1983-11-23. PMID:6312925. |
the synthesis of delta 1-tetrahydrocannabinol finally established the main active component of cannabis. |
1983-11-23 |
2023-08-12 |
Not clear |
| E S Watson, J C Murphy, C E Turne. Allergenic properties of naturally occurring cannabinoids. Journal of pharmaceutical sciences. vol 72. issue 8. 1983-11-23. PMID:6620158. |
cannabidiol, delta 8-tetrahydrocannabinol, and cannabichromene were moderate (grade iii) sensitizers. |
1983-11-23 |
2023-08-12 |
Not clear |
| L G Green, J L Stein, G S Stei. A decreased influence of cannabinoids on macromolecular biosynthesis and cell proliferation in human cells which metabolize polycyclic hydrocarbon carcinogens. Anticancer research. vol 3. issue 3. 1983-08-26. PMID:6191620. |
delta 9-thc, delta 8-thc, 11-oh-delta 9-thc, cannabinol and cannabidiol cause a dose-dependent inhibition of [3h]thymidine, [3h]uridine and [3h]leucine incorporation and a dose-dependent inhibition of cell growth in both normal and transformed human cells. |
1983-08-26 |
2023-08-12 |
human |
| P W Kujtan, P L Carlen, B M Kapu. delta 9-Tetrahydrocannabinol and cannabidiol: dose-dependent effects on evoked potentials in the hippocampal slice. Canadian journal of physiology and pharmacology. vol 61. issue 4. 1983-08-26. PMID:6305469. |
delta 9-tetrahydrocannabinol and cannabidiol: dose-dependent effects on evoked potentials in the hippocampal slice. |
1983-08-26 |
2023-08-12 |
Not clear |
| R Karler, S A Turkani. Subacute cannabinoid treatment: anticonvulsant activity and withdrawal excitability in mice. British journal of pharmacology. vol 68. issue 3. 1983-06-10. PMID:6301593. |
1 the effects of subacute treatment with cannabidiol, delta 9-tetrahydrocannabinol (delta 9-thc), phenytoin and phenobarbitone on anticonvulsant activity and on withdrawal excitability in mice were compared in three electrically induced seizure-threshold tests. |
1983-06-10 |
2023-08-12 |
mouse |
| R Karler, S A Turkani. Subacute cannabinoid treatment: anticonvulsant activity and withdrawal excitability in mice. British journal of pharmacology. vol 68. issue 3. 1983-06-10. PMID:6301593. |
2 in the maximal electroshock-threshold test, subacute treatment did not alter the anticonvulsant activity of cannabidiol, phenytoin or phenobarbitone, but tolerance developed to delta 9-thc. |
1983-06-10 |
2023-08-12 |
mouse |
| R Karler, S A Turkani. Subacute cannabinoid treatment: anticonvulsant activity and withdrawal excitability in mice. British journal of pharmacology. vol 68. issue 3. 1983-06-10. PMID:6301593. |
3 in the 60 hz electroshock-threshold test, the activity of delta 9-thc and cannabidiol did not change, but tolerance developed to phenobarbitone, and there was an increase in sensitivity to phenytoin. |
1983-06-10 |
2023-08-12 |
mouse |
| R Karler, S A Turkani. Subacute cannabinoid treatment: anticonvulsant activity and withdrawal excitability in mice. British journal of pharmacology. vol 68. issue 3. 1983-06-10. PMID:6301593. |
4 in the 6 hz electroshock-threshold test, there was an increase in sensitivity to both delta 9-thc and cannabidiol, there was tolerance to phenobarbitone, while the activity of phenytoin did not change. |
1983-06-10 |
2023-08-12 |
mouse |
| R Karler, S A Turkani. Subacute cannabinoid treatment: anticonvulsant activity and withdrawal excitability in mice. British journal of pharmacology. vol 68. issue 3. 1983-06-10. PMID:6301593. |
5 although tolerance developed in some of the seizure-threshold tests to delta 9-thc and phenobarbitone, tolerance to cannabidiol and phenytoin did not develop in any of the tests. |
1983-06-10 |
2023-08-12 |
mouse |
| W O Baczynsky, A M Zimmerma. Effects of delta 9-tetrahydrocannabinol, cannabinol and cannabidiol on the immune system in mice. I. In vivo investigation of the primary and secondary immune response. Pharmacology. vol 26. issue 1. 1983-04-07. PMID:6298841. |
effects of delta 9-tetrahydrocannabinol, cannabinol and cannabidiol on the immune system in mice. |
1983-04-07 |
2023-08-12 |
mouse |
| W O Baczynsky, A M Zimmerma. Effects of delta 9-tetrahydrocannabinol, cannabinol and cannabidiol on the immune system in mice. I. In vivo investigation of the primary and secondary immune response. Pharmacology. vol 26. issue 1. 1983-04-07. PMID:6298841. |
the effects of the cannabinoids delta 9-tetrahydrocannabinol (thc), cannabinol and cannabidiol on the primary humoral immune response, the secondary humoral immune response and the memory aspect of humoral immunity in response to sheep red blood cell (srbc) immunization was investigated. |
1983-04-07 |
2023-08-12 |
mouse |
| W O Baczynsky, A M Zimmerma. Effects of delta 9-tetrahydrocannabinol, cannabinol and cannabidiol on the immune system in mice. II. In vitro investigation using cultured mouse splenocytes. Pharmacology. vol 26. issue 1. 1983-04-07. PMID:6298842. |
effects of delta 9-tetrahydrocannabinol, cannabinol and cannabidiol on the immune system in mice. |
1983-04-07 |
2023-08-12 |
mouse |
| W O Baczynsky, A M Zimmerma. Effects of delta 9-tetrahydrocannabinol, cannabinol and cannabidiol on the immune system in mice. II. In vitro investigation using cultured mouse splenocytes. Pharmacology. vol 26. issue 1. 1983-04-07. PMID:6298842. |
the effects of the cannabinoids, delta 9-tetrahydrocannabinol (thc), cannabinol (cbn) and cannabidiol (cbd), on the primary-like immune response were investigated in primary cultures of mouse splenocytes. |
1983-04-07 |
2023-08-12 |
mouse |
| R G Almirez, C G Smith, R H Asc. The effects of marijuana extract and delta 9-tetrahydrocannabinol on luteal function in the rhesus monkey. Fertility and sterility. vol 39. issue 2. 1983-03-24. PMID:6295828. |
the effects of marijuana extract and delta 9-tetrahydrocannabinol on luteal function in the rhesus monkey. |
1983-03-24 |
2023-08-12 |
human |
| R G Almirez, C G Smith, R H Asc. The effects of marijuana extract and delta 9-tetrahydrocannabinol on luteal function in the rhesus monkey. Fertility and sterility. vol 39. issue 2. 1983-03-24. PMID:6295828. |
the effects of marijuana extract (me) and delta 9-tetrahydrocannabinol (thc) on corpus luteum function were studied in the rhesus monkey by the use of in vivo and in vitro techniques. |
1983-03-24 |
2023-08-12 |
human |
| R Reich, N Laufer, O Lewysohn, T Cordova, D Ayalon, A Tsafrir. In vitro effects of cannabinoids on follicular function in the rat. Biology of reproduction. vol 27. issue 1. 1982-12-02. PMID:6288130. |
the aim of the present study was to examine the direct effect of delta 1-thc, the psychoactive constituent of marihuana and cannabidiol (cbd), one of its nonpsychoactive constituents, on preovulatory rat follicles in vitro. |
1982-12-02 |
2023-08-12 |
rat |
| A Stiglick, H Kalan. Learning impairment in the radial-arm maze following prolonged cannabis treatment in rats. Psychopharmacology. vol 77. issue 2. 1982-12-02. PMID:6289370. |
chronic oral administration of cannabis extract to rats (daily delta 9-tetrahydrocannabinol dose 20 mg/kg) was examined in three experiments for its residual effect on radial-arm maze learning following a 1-month drug-free period. |
1982-12-02 |
2023-08-12 |
rat |
| A Stiglick, H Kalan. Residual effects of prolonged cannabis administration on exploration and DRL performance in rats. Psychopharmacology. vol 77. issue 2. 1982-12-02. PMID:6812129. |
chronic oral administration of cannabis extract to rats (daily delta 9-tetrahydrocannabinol dose 20 mg/kg) was examined for its residual effect on open field activity and drl (differential reinforcement of low-rat responding) performance, following a 2-3 month drug-free period. |
1982-12-02 |
2023-08-12 |
human |