| Publication |
Sentence |
Publish Date |
Extraction Date |
Species |
| A J Hiltunen, T U Järb. Interactions between delta 9-tetrahydrocannabinol and cannabidiol as evaluated by drug discrimination procedures in rats and pigeons. Neuropharmacology. vol 25. issue 2. 1986-05-23. PMID:3010159. |
cannabidiol prolonged the cue effects of 1 mg/kg of delta 9-thc (intraperitoneal route of administration) in rats but did not change the time-effect curve for delta 9-thc in pigeons (dose range examined: 0.10--0.56 mg/kg); the challenge doses of cannabidiol were, respectively: 30.0 mg/kg (i.p.) |
1986-05-23 |
2023-08-11 |
rat |
| A J Hiltunen, T U Järb. Interactions between delta 9-tetrahydrocannabinol and cannabidiol as evaluated by drug discrimination procedures in rats and pigeons. Neuropharmacology. vol 25. issue 2. 1986-05-23. PMID:3010159. |
the rate of responding did not differ in tests with combinations of delta 9-thc and cannabidiol as compared to delta 9-thc given alone in pigeons. |
1986-05-23 |
2023-08-11 |
rat |
| G Nahas, R Trouv. Effects and interactions of natural cannabinoids on the isolated heart. Proceedings of the Society for Experimental Biology and Medicine. Society for Experimental Biology and Medicine (New York, N.Y.). vol 180. issue 2. 1985-11-20. PMID:4048169. |
cardiac toxicity is observed with 3 x 10(-5) m. cannabidiol (cbd) at concentrations of 9 x 10(-6) m to 10(-4) m has limited effect on rate while increasing delta p and coronary flow. |
1985-11-20 |
2023-08-11 |
rat |
| J T Ungerleider, T Andrysia. Therapeutic issues of marijuana and THC (tetrahydrocannabinol). The International journal of the addictions. vol 20. issue 5. 1985-11-14. PMID:2995262. |
this article summarizes current knowledge about the medicinal value of cannabis and its principal psychoactive ingredient, delta 9-tetrahydrocannabinol (thc), particularly in the control of nausea and vomiting, in glaucoma, and in reduction of spasticity in multiple sclerosis. |
1985-11-14 |
2023-08-11 |
Not clear |
| H R Frischknecht, B Siegfried, M Schiller, P G Wase. Hashish extract impairs retention of defeat-induced submissive behavior in mice. Psychopharmacology. vol 86. issue 3. 1985-10-01. PMID:2994143. |
a hashish extract containing 38.6-39.4% delta 9-tetrahydrocannabinol (delta 9-thc), 11.6-12.0% cannabinol and 47.7-48.5% cannabidiol was administered orally in all experiments. |
1985-10-01 |
2023-08-11 |
mouse |
| L D Chait, M W Fischman, C R Schuste. 'Hangover' effects the morning after marijuana smoking. Drug and alcohol dependence. vol 15. issue 3. 1985-09-30. PMID:2992898. |
subjects smoked either active (2.9% delta 9thc) or placebo (0.0% delta 9thc) marijuana cigarettes according to a standardized smoking regimen. |
1985-09-30 |
2023-08-11 |
human |
| G D Braunstein, R Thompson, S Gross, J R Soare. Marijuana use does not spuriously elevate serum human chorionic gonadotropin levels. Urology. vol 25. issue 6. 1985-07-30. PMID:2990078. |
to reinvestigate this finding, we measured serum hcg and delta 9-tetrahydrocannabinol (delta 9-thc) levels in 16 men known or suspected to be marijuana users. |
1985-07-30 |
2023-08-11 |
human |
| V S Jorapur, Z H Khalil, R P Duffley, R K Razdan, B R Martin, L S Harris, W L Dewe. Hashish: synthesis and central nervous system activity of some novel analogues of cannabidiol and oxepin derivatives of delta 9-tetrahydrocannabinol. Journal of medicinal chemistry. vol 28. issue 6. 1985-07-29. PMID:2989518. |
hashish: synthesis and central nervous system activity of some novel analogues of cannabidiol and oxepin derivatives of delta 9-tetrahydrocannabinol. |
1985-07-29 |
2023-08-11 |
mouse |
| V S Jorapur, Z H Khalil, R P Duffley, R K Razdan, B R Martin, L S Harris, W L Dewe. Hashish: synthesis and central nervous system activity of some novel analogues of cannabidiol and oxepin derivatives of delta 9-tetrahydrocannabinol. Journal of medicinal chemistry. vol 28. issue 6. 1985-07-29. PMID:2989518. |
several c-10 substituted cannabidiol (cbd) derivatives and novel oxepin derivatives of delta 9-tetrahydrocannabinol (delta 9-thc) were synthesized and evaluated for biological activity in mice and dogs. |
1985-07-29 |
2023-08-11 |
mouse |
| S J Gross, T E Worthy, L Nerder, E G Zimmermann, J R Soares, P Loma. Detection of recent cannabis use by saliva delta 9-THC radioimmunoassay. Journal of analytical toxicology. vol 9. issue 1. 1985-05-08. PMID:2984463. |
detection of recent cannabis use by saliva delta 9-thc radioimmunoassay. |
1985-05-08 |
2023-08-11 |
human |
| S J Gross, T E Worthy, L Nerder, E G Zimmermann, J R Soares, P Loma. Detection of recent cannabis use by saliva delta 9-THC radioimmunoassay. Journal of analytical toxicology. vol 9. issue 1. 1985-05-08. PMID:2984463. |
a non-invasive saliva sample delta 9-thc radioimmunoassay has been applied to 352 samples from 25 male and 10 female marijuana users after administration of one-half to two standard cigarettes (27 mg delta 9-thc/cigarette) and 72 control negative subjects who ingested a large variety of foods, condiments, or medications in an attempt to demonstrate interferences. |
1985-05-08 |
2023-08-11 |
human |
| B K Colasanti, R E Brown, C R Crai. Ocular hypotension, ocular toxicity, and neurotoxicity in response to marihuana extract and cannabidiol. General pharmacology. vol 15. issue 6. 1985-04-18. PMID:6098513. |
while marihuana extract and delta 9-thc produced a dose-related increase in the appearance of 8-13 hz polyspike discharges in the electrocorticograms of rats, both polyethylene glycol and cannabidiol lacked this effect. |
1985-04-18 |
2023-08-12 |
rat |
| J M van Ree, R J Niesink, I Ni. delta 1-Tetrahydrocannabinol but not cannabidiol reduces contact and aggressive behavior of rats tested in dyadic encounters. Psychopharmacology. vol 84. issue 4. 1985-03-25. PMID:6098915. |
delta 1-tetrahydrocannabinol but not cannabidiol reduces contact and aggressive behavior of rats tested in dyadic encounters. |
1985-03-25 |
2023-08-12 |
rat |
| J M van Ree, R J Niesink, I Ni. delta 1-Tetrahydrocannabinol but not cannabidiol reduces contact and aggressive behavior of rats tested in dyadic encounters. Psychopharmacology. vol 84. issue 4. 1985-03-25. PMID:6098915. |
a low and a high dose of delta 1-tetrahydrocannabinol (delta 1-thc) and of cannabidiol (cbd) were ip injected in rats that had been isolated for 7 days. |
1985-03-25 |
2023-08-12 |
rat |
| E J Essma. Marijuana intoxication in rats: interruption of recent memory and effect on brain concentration of delta 9-tetrahydrocannabinol. Psychological reports. vol 55. issue 2. 1985-01-31. PMID:6096910. |
marijuana intoxication in rats: interruption of recent memory and effect on brain concentration of delta 9-tetrahydrocannabinol. |
1985-01-31 |
2023-08-12 |
rat |
| S K Tilak, A M Zimmerma. Effects of cannabinoids on macromolecular synthesis in isolated spermatogenic cells. Pharmacology. vol 29. issue 6. 1985-01-14. PMID:6209733. |
effects of delta 9-tetrahydrocannabinol (thc), cannabinol (cbn) and cannabidiol (cbd) (1, 3 or 5 microm for 2 h) on macromolecular synthesis were investigated in homogeneous populations of pachytene spermatocytes and round spermatids obtained from cd-1 mice. |
1985-01-14 |
2023-08-12 |
mouse |
| B Law, P A Mason, A C Moffat, L J King, V Mark. Passive inhalation of cannabis smoke. The Journal of pharmacy and pharmacology. vol 36. issue 9. 1984-12-20. PMID:6149279. |
six volunteers each smoked simultaneously, in a small unventilated room (volume 27 950 litre), a cannabis cigarette containing 17.1 mg delta 9-tetrahydrocannabinol (thc). |
1984-12-20 |
2023-08-12 |
human |
| J H Mendelson, N K Mell. Reinforcing properties of oral delta 9-tetrahydrocannabinol, smoked marijuana, and nabilone: influence of previous marijuana use. Psychopharmacology. vol 83. issue 4. 1984-12-12. PMID:6149589. |
reinforcing properties of oral delta 9-tetrahydrocannabinol, smoked marijuana, and nabilone: influence of previous marijuana use. |
1984-12-12 |
2023-08-12 |
human |
| J H Mendelson, N K Mell. Reinforcing properties of oral delta 9-tetrahydrocannabinol, smoked marijuana, and nabilone: influence of previous marijuana use. Psychopharmacology. vol 83. issue 4. 1984-12-12. PMID:6149589. |
the reinforcing properties of delta 9thc (17.5 mg), a 1 g marijuana cigarette containing 1.83% delta 9-thc, a synthetic cannabis compound (nabilone 2 mg orally), and their respective placebos were assessed with self-report and operant work-contingent choice procedures. |
1984-12-12 |
2023-08-12 |
human |
| A W Zuardi, N A Teixeira, I C Karnio. Pharmacological interaction of the effects of delta 9-trans-tetrahydrocannabinol and cannabidiol on serum corticosterone levels in rats. Archives internationales de pharmacodynamie et de therapie. vol 269. issue 1. 1984-09-17. PMID:6087750. |
pharmacological interaction of the effects of delta 9-trans-tetrahydrocannabinol and cannabidiol on serum corticosterone levels in rats. |
1984-09-17 |
2023-08-12 |
rat |