| Publication |
Sentence |
Publish Date |
Extraction Date |
Species |
| L D Chait, S M Evans, K A Grant, J B Kamien, C E Johanson, C R Schuste. Discriminative stimulus and subjective effects of smoked marijuana in humans. Psychopharmacology. vol 94. issue 2. 1988-05-03. PMID:3127846. |
the discriminative stimulus (ds) effects of smoked marijuana were studied by training marijuana smokers to discriminate between the effects of marijuana containing 2.7% delta 9-thc (m) and marijuana containing 0.0% delta 9-thc (p). |
1988-05-03 |
2023-08-11 |
human |
| L D Chait, S M Evans, K A Grant, J B Kamien, C E Johanson, C R Schuste. Discriminative stimulus and subjective effects of smoked marijuana in humans. Psychopharmacology. vol 94. issue 2. 1988-05-03. PMID:3127846. |
the ds effects were dose dependent, with 0.9% delta 9-thc marijuana producing primarily placebo-appropriate discrimination responding, and 1.4% delta 9-thc marijuana producing 100% drug-appropriate responding. |
1988-05-03 |
2023-08-11 |
human |
| M K Ashfaq, E S Watson, H N elSohl. The effect of subacute marijuana smoke inhalation on experimentally induced dermonecrosis by S. aureus infection. Immunopharmacology and immunotoxicology. vol 9. issue 2-3. 1988-03-25. PMID:2830328. |
this model was used to assess the effects of marijuana smoke, marijuana placebo smoke and delta 9-tetrahydrocannabinol (delta 9-thc) on the local immune response to bacterial infection. |
1988-03-25 |
2023-08-11 |
mouse |
| M K Ashfaq, E S Watson, H N elSohl. The effect of subacute marijuana smoke inhalation on experimentally induced dermonecrosis by S. aureus infection. Immunopharmacology and immunotoxicology. vol 9. issue 2-3. 1988-03-25. PMID:2830328. |
the estimated dose of delta 9thc per day generated from 40 or 80 puffs of marijuana smoke was 3.2 and 6.4 mg/kg, respectively. |
1988-03-25 |
2023-08-11 |
mouse |
| M K Ashfaq, E S Watson, H N elSohl. The effect of subacute marijuana smoke inhalation on experimentally induced dermonecrosis by S. aureus infection. Immunopharmacology and immunotoxicology. vol 9. issue 2-3. 1988-03-25. PMID:2830328. |
placebo marijuana smoke exposed mice had a ni comparable to that of marijuana smoke exposed mice which suggested that the reduction in ni was unrelated to the pychomimetic component delta 9thc. |
1988-03-25 |
2023-08-11 |
mouse |
| R W Foltin, M W Fischman, J J Pedroso, G D Pearlso. Marijuana and cocaine interactions in humans: cardiovascular consequences. Pharmacology, biochemistry, and behavior. vol 28. issue 4. 1988-03-10. PMID:2829241. |
following the determination of baseline cardiovascular indexes, a one gram marijuana cigarette (0-2.7% delta 9-thc w/w) was smoked. |
1988-03-10 |
2023-08-11 |
human |
| T C Wu, D P Tashkin, B Djahed, J E Ros. Pulmonary hazards of smoking marijuana as compared with tobacco. The New England journal of medicine. vol 318. issue 6. 1988-02-26. PMID:3340105. |
we measured each subject's blood carboxyhemoglobin level before and after smoking and the amount of tar inhaled and deposited in the respiratory tract from the smoke of single filter-tipped tobacco cigarettes (900 to 1200 mg) and marijuana cigarettes (741 to 985 mg) containing 0.004 percent or 1.24 percent delta 9-tetrahydrocanabinol. |
1988-02-26 |
2023-08-11 |
human |
| E L Abel, S E Tan, M Subramania. Effects of delta 9-tetrahydrocannabinol, phenobarbital, and their combination on pregnancy and offspring in rats. Teratology. vol 36. issue 2. 1988-01-29. PMID:2827333. |
levels of delta 9-thc in blood approximated levels attained in humans after smoking one to two marijuana cigarettes. |
1988-01-29 |
2023-08-11 |
mouse |
| R W Foltin, J V Brady, M W Fischman, C S Emurian, J Dominit. Effects of smoked marijuana on social interaction in small groups. Drug and alcohol dependence. vol 20. issue 1. 1987-12-21. PMID:3678046. |
four cigarettes containing active marijuana (1.84%, delta 9-tetrahydrocannabinol (delta 9 (thc)), w/w) or placebo were smoked daily: one each prior to the work and social access period, and two during the social access period. |
1987-12-21 |
2023-08-11 |
human |
| D L King, P A Martel, C M O'Donnel. Laboratory detection of cannabinoids. Clinics in laboratory medicine. vol 7. issue 3. 1987-11-05. PMID:3308300. |
although therapeutic applications of cannabis constituents often produce undesirable side effects, two cannabinoids, delta 9-thc and nabilone, have been approved for use as antiemetics in chemotherapy. |
1987-11-05 |
2023-08-11 |
Not clear |
| J R Bailey, H C Cunny, M G Paule, W Slikke. Fetal disposition of delta 9-tetrahydrocannabinol (THC) during late pregnancy in the rhesus monkey. Toxicology and applied pharmacology. vol 90. issue 2. 1987-10-16. PMID:2820086. |
three late-term (gestational days 146-151) rhesus monkeys were given 0.3 mg/kg delta 9-tetrahydrocannabinol (thc) intravenously via the maternal radial vein to quantify the placental transfer and fetal disposition of thc, the major psychoactive component of marijuana. |
1987-10-16 |
2023-08-11 |
monkey |
| H L Tripathi, F J Vocci, D A Brase, W L Dewe. Effects of cannabinoids on levels of acetylcholine and choline and on turnover rate of acetylcholine in various regions of the mouse brain. Alcohol and drug research. vol 7. issue 5-6. 1987-10-16. PMID:3620017. |
the psychoactive cannabinoids, delta 9-tetrahydrocannabinol (delta 9-thc), delta 8-tetrahydrocannabinol (delta 8-thc), 11-hydroxy-delta 9-tetrahydrocannabinol (11-oh-delta 9-thc) and 9-nor-9 beta-hydroxyhexahydrocannabinol (beta-hhc), as well as the nonpsychoactive cannabinoids, cannabinol (cbn), cannabidiol (cbd), abnormal cbd, delta 8-thc methyl ether (1-och3-delta 8-thc) and 9-nor-9 alpha-hydroxyhexahydrocannabinol (alpha-hhc), were used to assess the role of cholinergic mechanisms in the different behavioral actions of these cannabinoids. |
1987-10-16 |
2023-08-11 |
mouse |
| G Murison, C B Chubb, S Maeda, M A Gemmell, E Huberma. Cannabinoids induce incomplete maturation of cultured human leukemia cells. Proceedings of the National Academy of Sciences of the United States of America. vol 84. issue 15. 1987-08-26. PMID:3037549. |
monocyte maturation markers were induced in cultured human myeloblastic ml-2 leukemia cells after treatment for 1-6 days with 0.03-30 microm delta 9-tetrahydrocannabinol (thc), the major psychoactive component of marijuana. |
1987-08-26 |
2023-08-11 |
human |
| V M Wiegant, C G Sweep, I Ni. Effect of acute administration of delta 1-tetrahydrocannabinol on beta-endorphin levels in plasma and brain tissue of the rat. Experientia. vol 43. issue 4. 1987-06-01. PMID:3032670. |
these effects were not obtained with the psychotropically inert analog of delta 1-thc, cannabidiol. |
1987-06-01 |
2023-08-11 |
rat |
| H Schuel, R Schuel, A M Zimmerman, S Zimmerma. Cannabinoids reduce fertility of sea urchin sperm. Biochemistry and cell biology = Biochimie et biologie cellulaire. vol 65. issue 2. 1987-05-20. PMID:3030370. |
the effects of delta 9-tetrahydrocannabinol (thc), cannabinol (cbn), and cannabidiol (cbd) on fertilization in the sea urchin strongylocentrotus purpuratus were investigated. |
1987-05-20 |
2023-08-11 |
Not clear |
| A T Evans, E Formukong, F J Evan. Activation of phospholipase A2 by cannabinoids. Lack of correlation with CNS effects. FEBS letters. vol 211. issue 2. 1987-03-03. PMID:3803591. |
cannabinoids delta 1-tetrahydrocannabinol, cannabinol, cannabidiol and cannabigerol have been shown to affect directly the activity of phospholipase a2 in a cell-free assay. |
1987-03-03 |
2023-08-11 |
human |
| A T Evans, E Formukong, F J Evan. Activation of phospholipase A2 by cannabinoids. Lack of correlation with CNS effects. FEBS letters. vol 211. issue 2. 1987-03-03. PMID:3803591. |
however, since delta 1-tetrahydrocannabinol is unique among these compounds in possessing cataleptic activity, it is unlikely that phospholipase a2 is the major receptor mediating the psychotropic effects of cannabis. |
1987-03-03 |
2023-08-11 |
human |
| J H Liu, A C Dacu. Central nervous system and peripheral mechanisms in ocular hypotensive effect of cannabinoids. Archives of ophthalmology (Chicago, Ill. : 1960). vol 105. issue 2. 1987-03-02. PMID:3813958. |
when delta 9-tetrahydrocannabinol (delta 9-thc), delta 8-tetrahydrocannabinol, cannabinol, and cannabidiol were given intravenously, only delta 9-thc produced dose-dependent ocular hypotension and miosis. |
1987-03-02 |
2023-08-11 |
Not clear |
| R H Asch, C G Smit. Effects of delta 9-THC, the principal psychoactive component of marijuana, during pregnancy in the rhesus monkey. The Journal of reproductive medicine. vol 31. issue 12. 1987-02-10. PMID:3025441. |
effects of delta 9-thc, the principal psychoactive component of marijuana, during pregnancy in the rhesus monkey. |
1987-02-10 |
2023-08-11 |
monkey |
| R H Asch, C G Smit. Effects of delta 9-THC, the principal psychoactive component of marijuana, during pregnancy in the rhesus monkey. The Journal of reproductive medicine. vol 31. issue 12. 1987-02-10. PMID:3025441. |
the effect of delta 9-tetrahydrocannabinol (thc), the principal psychoactive component in marijuana, was studied in pregnant and lactating rhesus monkeys. |
1987-02-10 |
2023-08-11 |
monkey |